3282 lines
151 KiB
C#
3282 lines
151 KiB
C#
using IRaCIS.Core.Application.Service.Reading.Dto;
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using IRaCIS.Core.Domain.Share;
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using Microsoft.AspNetCore.Mvc;
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using IRaCIS.Core.Domain.Models;
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using Microsoft.AspNetCore.Mvc;
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using IRaCIS.Core.Application.Interfaces;
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using IRaCIS.Core.Application.ViewModel;
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using Panda.DynamicWebApi.Attributes;
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using IRaCIS.Core.Infra.EFCore.Common;
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using Microsoft.Extensions.Caching.Memory;
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using IRaCIS.Core.Infrastructure;
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using MassTransit;
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namespace IRaCIS.Core.Application.Service.ReadingCalculate
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{
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[ApiExplorerSettings(GroupName = "Reading")]
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public class IRECIST1Point1CalculateService : BaseService, ICriterionCalculateService
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{
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private readonly IRepository<ReadingTableQuestionAnswer> _readingTableQuestionAnswerRepository;
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private readonly IRepository<VisitTask> _visitTaskRepository;
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private readonly IRepository<ReadingQuestionCriterionTrial> _readingQuestionCriterionTrialRepository;
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private readonly IRepository<ReadingTableQuestionTrial> _readingTableQuestionTrialRepository;
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private readonly IRepository<ReadingTableAnswerRowInfo> _readingTableAnswerRowInfoRepository;
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private readonly IRepository<ReadingQuestionTrial> _readingQuestionTrialRepository;
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private readonly IRepository<OrganInfo> _organInfoRepository;
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private readonly IRepository<SubjectVisit> _subjectVisitRepository;
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private readonly IRepository<TumorAssessment_IRECIST1Point1> _tumorAssessmentRepository;
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private readonly IGeneralCalculateService _generalCalculateService;
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private readonly IRepository<ReadingTaskQuestionAnswer> _readingTaskQuestionAnswerRepository;
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public IRECIST1Point1CalculateService(
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IRepository<ReadingTableQuestionAnswer> readingTableQuestionAnswerRepository,
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IRepository<VisitTask> visitTaskRepository,
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IRepository<ReadingQuestionCriterionTrial> readingQuestionCriterionTrialRepository,
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IRepository<ReadingTableQuestionTrial> readingTableQuestionTrialRepository,
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IRepository<ReadingTableAnswerRowInfo> readingTableAnswerRowInfoRepository,
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IRepository<ReadingQuestionTrial> readingQuestionTrialRepository,
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IRepository<OrganInfo> organInfoRepository,
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IRepository<SubjectVisit> subjectVisitRepository,
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IRepository<TumorAssessment_IRECIST1Point1> tumorAssessmentRepository,
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IGeneralCalculateService generalCalculateService,
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IRepository<ReadingTaskQuestionAnswer> readingTaskQuestionAnswerRepository
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)
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{
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this._readingTableQuestionAnswerRepository = readingTableQuestionAnswerRepository;
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this._visitTaskRepository = visitTaskRepository;
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this._readingQuestionCriterionTrialRepository = readingQuestionCriterionTrialRepository;
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this._readingTableQuestionTrialRepository = readingTableQuestionTrialRepository;
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this._readingTableAnswerRowInfoRepository = readingTableAnswerRowInfoRepository;
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this._readingQuestionTrialRepository = readingQuestionTrialRepository;
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this._organInfoRepository = organInfoRepository;
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this._subjectVisitRepository = subjectVisitRepository;
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this._tumorAssessmentRepository = tumorAssessmentRepository;
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this._generalCalculateService = generalCalculateService;
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this._readingTaskQuestionAnswerRepository = readingTaskQuestionAnswerRepository;
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}
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#region 临时对象 单个请求的生命周期 避免重复查询数据库
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private List<VisitTaskAnswerInfo> visitTaskAnswerList;
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/// <summary>
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/// 获取Sod的值
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/// </summary>
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private decimal? sODData;
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/// <summary>
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/// 获取iSod的值
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/// </summary>
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private decimal? iSODData;
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private string nAString = "NA";
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/// <summary>
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/// 上一次访视Id
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/// </summary>
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public Guid? lastVisitTaskId;
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#endregion
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#region 删除病灶获取起始病灶序号
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/// <summary>
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/// 删除病灶获取起始病灶序号（RECIST1Point1 固定是1）
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/// </summary>
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/// <returns></returns>
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public async Task<int> GetDeleteLesionStatrIndex(DeleteReadingRowAnswerInDto inDto)
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{
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return 1;
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}
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#endregion
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#region 获取阅片报告
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/// <summary>
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/// 获取阅片报告
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/// </summary>
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/// <param name="indto"></param>
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/// <returns></returns>
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[HttpPost]
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public async Task<GetReadingReportEvaluationOutDto> GetReadingReportEvaluation(GetReadingReportEvaluationInDto indto)
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{
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GetReadingReportEvaluationOutDto result = new GetReadingReportEvaluationOutDto();
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var isConvertTask = await _visitTaskRepository.Where(x => x.Id == indto.VisitTaskId).Select(x => x.IsConvertedTask).FirstNotNullAsync();
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var visitTaskInfo = await _visitTaskRepository.Where(x => x.Id == indto.VisitTaskId).FirstNotNullAsync();
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result.CalculateResult = await this.GetReportVerify(new GetReportVerifyInDto()
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{
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VisitTaskId = indto.VisitTaskId,
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IsConvertTask= isConvertTask,
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BeforeConvertedTaskId =visitTaskInfo.BeforeConvertedTaskId,
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});
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result.ReadingTaskState = visitTaskInfo.ReadingTaskState;
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var taskInfoList = await _generalCalculateService.GetReadingReportTaskList(indto.VisitTaskId);
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result.VisitTaskList = taskInfoList;
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var visitTaskIds = taskInfoList.Select(x => x.VisitTaskId).ToList();
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var criterionId = visitTaskInfo.TrialReadingCriterionId;
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var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId&&x.ShowQuestion!= ShowQuestion.Hide)
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.WhereIf(isConvertTask,x=>x.ConvertShowType==ConvertShowType.All||x.ConvertShowType==ConvertShowType.AfterShow)
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.WhereIf(!isConvertTask, x => x.ConvertShowType == ConvertShowType.All || x.ConvertShowType == ConvertShowType.BeforeShow)
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.ToListAsync();
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var tableQuestionList = await _readingTableQuestionTrialRepository.Where(x => x.TrialCriterionId == criterionId).OrderBy(x => x.ShowOrder).ToListAsync();
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var tableAnsweRowInfos = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == indto.VisitTaskId).ProjectTo<TableAnsweRowInfo>(_mapper.ConfigurationProvider).ToListAsync();
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result.LesionCountList = tableAnsweRowInfos.GroupBy(x => x.LesionType).Select(x => new LesionDto
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{
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LesionType = x.Key.Value,
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Count = x.ToList().Count()
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}).ToList();
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var lesionsIndexs = await _readingTableAnswerRowInfoRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).GroupBy(x => new { x.QuestionId }).Select(x => new lesionsIndexDto()
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{
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QuestionId = x.Key.QuestionId,
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Rowindexs = x.Select(x => x.RowIndex).Distinct().OrderBy(x => x).ToList()
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}).ToListAsync();
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var answers = await _readingTaskQuestionAnswerRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).ToListAsync();
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var tableAnswers = await _readingTableQuestionAnswerRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).ToListAsync();
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var alltableAnsweRowInfos = await _readingTableAnswerRowInfoRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).ToListAsync();
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var organIds = alltableAnsweRowInfos.Where(x => x.OrganInfoId != null).Select(x => x.OrganInfoId).Distinct().ToList();
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var organInfos = await _organInfoRepository.Where(x => organIds.Contains(x.Id)).ToListAsync();
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var needChangeType = new List<QuestionMark?>() {
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QuestionMark.Organ,
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QuestionMark.Location,
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QuestionMark.Part,
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};
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// 第一级
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#region 构造问题
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List<ReadingReportDto> questions = questionList.Where(x => x.Type == ReadingQestionType.Group).OrderBy(x => x.ShowOrder).Select(x => new ReadingReportDto()
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{
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QuestionId = x.Id,
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GroupName = x.GroupName,
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GroupEnName=x.GroupEnName,
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IsShowInDicom = x.IsShowInDicom,
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Type = x.Type,
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GroupId=x.GroupId,
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QuestionType = x.QuestionType,
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LesionType = x.LesionType,
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QuestionGenre = x.QuestionGenre,
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DataSource = x.DataSource,
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DictionaryCode = x.DictionaryCode,
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TypeValue = x.TypeValue,
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QuestionName = x.QuestionName.LanguageName(x.QuestionEnName, _userInfo.IsEn_Us),
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ShowOrder = x.ShowOrder,
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ValueType = x.ValueType,
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Unit = x.Unit,
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CustomUnit=x.CustomUnit,
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ReportLayType= ReportLayType.Group,
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}).ToList();
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// 分组
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foreach (var item in questions)
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{
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item.Childrens = questionList.Where(x => x.GroupId==item.QuestionId).OrderBy(x => x.ShowOrder).Select(x => new ReadingReportDto()
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{
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GroupName = x.GroupName,
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QuestionId = x.Id,
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IsShowInDicom = x.IsShowInDicom,
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GroupEnName=x.GroupEnName,
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QuestionName = x.QuestionName.LanguageName(x.QuestionEnName, _userInfo.IsEn_Us),
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LesionType = x.LesionType,
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QuestionGenre = x.QuestionGenre,
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DataSource = x.DataSource,
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DictionaryCode = x.DictionaryCode,
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Type = x.Type,
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QuestionType = x.QuestionType,
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TypeValue = x.TypeValue,
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ShowOrder = x.ShowOrder,
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OrderMark = x.OrderMark,
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ValueType = x.ValueType,
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Unit = x.Unit,
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CustomUnit=x.CustomUnit,
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ReportLayType = ReportLayType.Question,
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}).ToList();
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// 问题
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foreach (var question in item.Childrens)
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{
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foreach (var task in taskInfoList)
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{
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var answer = answers.Where(x => x.VisitTaskId == task.VisitTaskId && x.ReadingQuestionTrialId == question.QuestionId).FirstOrDefault();
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question.Answer.Add(new TaskQuestionAnswer()
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{
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Answer = answer==null?string.Empty:answer.Answer,
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IsGlobalChange = answer == null ? false : answer.IsGlobalChange,
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GlobalChangeAnswer = answer == null ? string.Empty : answer.GlobalChangeAnswer,
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TaskName = task.TaskName,
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VisitTaskId = task.VisitTaskId,
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});
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}
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// 构造表格行数据
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var rowlist = tableAnsweRowInfos.Where(x => x.QuestionId == question.QuestionId).OrderBy(x => x.RowIndex).ToList();
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question.Childrens = new List<ReadingReportDto>();
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var rowoindexs = lesionsIndexs.Where(x => x.QuestionId == question.QuestionId).Select(x => x.Rowindexs.OrderBy(y => y).ToList()).FirstOrDefault();
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rowoindexs = rowoindexs == null ? new List<decimal>() : rowoindexs;
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foreach (var rowoindex in rowoindexs)
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{
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var rowinfo = rowlist.Where(x => x.RowIndex == rowoindex).FirstOrDefault();
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question.Childrens.Add(new ReadingReportDto()
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{
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QuestionName = question.OrderMark + rowoindex.GetLesionMark(),
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RowId = rowinfo?.Id,
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IsShowInDicom = question.IsShowInDicom,
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SplitOrMergeLesionName = rowinfo != null ? (rowinfo.MergeName.IsNullOrEmpty() ? rowinfo.SplitName : rowinfo.MergeName) : string.Empty,
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SplitOrMergeType = rowinfo != null ? (rowinfo.SplitOrMergeType) : null,
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LesionType = question.LesionType,
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IsCanEditPosition = rowinfo != null ? (rowinfo.IsCanEditPosition) : false,
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RowIndex = rowoindex,
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BlindName = rowinfo != null ? rowinfo.BlindName : string.Empty,
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ReportLayType = ReportLayType.Lesions,
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});
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}
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foreach (var row in question.Childrens)
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{
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// tableQuestion
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row.Childrens = tableQuestionList.Where(x => x.ReadingQuestionId == question.QuestionId).Select(x => new ReadingReportDto()
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{
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QuestionName = x.QuestionName.LanguageName(x.QuestionEnName, _userInfo.IsEn_Us),
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QuestionId = x.ReadingQuestionId,
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TableQuestionId = x.Id,
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Type = x.Type,
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LesionType = question.LesionType,
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TableQuestionType = x.TableQuestionType,
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RowId=row.RowId,
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IsShowInDicom = question.IsShowInDicom,
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DataSource = x.DataSource,
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DictionaryCode = x.DictionaryCode,
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QuestionMark = x.QuestionMark,
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TypeValue = x.TypeValue,
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RowIndex = row.RowIndex,
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ShowOrder = x.ShowOrder,
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ValueType = x.ValueType,
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Unit = x.Unit,
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ReportLayType = ReportLayType.TableQuestion,
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}).ToList();
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foreach (var tableQuestion in row.Childrens)
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{
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foreach (var task in taskInfoList)
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{
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var rowinfo = alltableAnsweRowInfos.Where(x => x.VisitTaskId == task.VisitTaskId && x.QuestionId == tableQuestion.QuestionId && x.RowIndex == tableQuestion.RowIndex).FirstOrDefault();
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var taskQuestionAnswer = new TaskQuestionAnswer()
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{
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Answer = tableAnswers.Where(x => x.VisitTaskId == task.VisitTaskId && x.QuestionId == tableQuestion.QuestionId && x.RowIndex == tableQuestion.RowIndex && x.TableQuestionId == tableQuestion.TableQuestionId).Select(x => x.Answer).FirstIsNullReturnEmpty(),
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TaskName = task.TaskName,
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VisitTaskId = task.VisitTaskId,
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};
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if (rowinfo != null && rowinfo.OrganInfoId != null)
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{
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var organInfo = organInfos.Where(x => x.Id == rowinfo.OrganInfoId).FirstOrDefault();
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if (organInfo != null && needChangeType.Contains(tableQuestion.QuestionMark))
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{
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if (_userInfo.IsEn_Us)
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{
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switch (tableQuestion.QuestionMark)
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{
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case QuestionMark.Organ:
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taskQuestionAnswer.Answer= organInfo.TULOCEN;
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break;
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case QuestionMark.Location:
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if (organInfo.IsCanEditPosition)
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{
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}
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else
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{
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taskQuestionAnswer.Answer = organInfo.TULATEN;
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}
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break;
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case QuestionMark.Part:
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taskQuestionAnswer.Answer = organInfo.PartEN;
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break;
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}
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}
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else
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{
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switch (tableQuestion.QuestionMark)
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{
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case QuestionMark.Organ:
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taskQuestionAnswer.Answer = organInfo.TULOC;
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break;
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case QuestionMark.Location:
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if (organInfo.IsCanEditPosition)
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{
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}
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else
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{
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taskQuestionAnswer.Answer = organInfo.TULAT;
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}
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break;
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case QuestionMark.Part:
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taskQuestionAnswer.Answer = organInfo.Part;
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break;
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}
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}
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}
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}
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tableQuestion.Answer.Add(taskQuestionAnswer);
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}
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}
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}
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};
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}
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#endregion
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result.TaskQuestions = questions;
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return result;
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}
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#endregion
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/// <summary>
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/// 测试计算
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/// </summary>
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/// <param name="visitTaskId"></param>
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/// <param name="type"></param>
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/// <returns></returns>
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[HttpPost]
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public async Task TestCalculate(Guid visitTaskId, QuestionType type)
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{
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ReadingCalculateDto readingData = await _generalCalculateService.GetReadingCalculateDto(visitTaskId);
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await ReadingCalculate(readingData,new List<QuestionType>() { type});
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}
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/// <summary>
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/// 计算任务
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/// </summary>
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/// <param name="inDto"></param>
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/// <returns></returns>
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[HttpPost]
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public async Task CalculateTask(CalculateTaskInDto inDto)
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{
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ReadingCalculateDto readingData = await _generalCalculateService.GetReadingCalculateDto(inDto.VisitTaskId);
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readingData.IsChangeOtherTask = inDto.IsChangeOtherTask;
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await ReadingCalculate(readingData);
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}
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/// <summary>
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/// 获取报告验证的信息(这里每个标准可能不一样 返回用object)
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/// </summary>
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/// <param name="inDto"></param>
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/// <returns></returns>
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public async Task<object> GetReportVerify(GetReportVerifyInDto inDto)
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{
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var tumorEvaluate = string.Empty;
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var readingCalculateDto= await _generalCalculateService.GetReadingCalculateDto(inDto.VisitTaskId);
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if (!inDto.IsConvertTask)
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{
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tumorEvaluate = await GetTumor(readingCalculateDto);
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}
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else if (inDto.BeforeConvertedTaskId != null)
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{
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tumorEvaluate = await GetConvertingTumor(readingCalculateDto);
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}
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else
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{
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tumorEvaluate = await GetIRECSITTargetLesionEvaluate(readingCalculateDto);
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}
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return new
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{
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TumorEvaluate = tumorEvaluate,
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IsExistDisease = await this.GetReportIsExistDisease(inDto.VisitTaskId),
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};
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}
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/// <summary>
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/// 自动计算
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/// </summary>
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/// <param name="inDto"></param>
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/// <param name="calculateType"></param>
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/// <returns></returns>
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public async Task ReadingCalculate(ReadingCalculateDto inDto,List<QuestionType> calculateType=null)
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{
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#region 计算 这里顺序非常重要 后面计算的值要依赖前面计算的结果
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var needAddList = new List<ReadingTaskQuestionAnswer>();
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List<ReadingCalculateData> calculateList = new List<ReadingCalculateData>()
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{
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//靶病灶径线之和（SOD）
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new ReadingCalculateData (){QuestionType=QuestionType.SOD,GetDecimalNullFun=GetSODData},
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//非淋巴结靶病灶长径之和
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new ReadingCalculateData (){QuestionType=QuestionType.SumOfDiameter,GetDecimalNullFun=GetSumOfDiameter},
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//与基线SOD相比变化量（mm）
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new ReadingCalculateData (){QuestionType=QuestionType.SODChange,GetDecimalNullFun=GetSODChange},
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//与基线访视相比SOD变化百分比
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new ReadingCalculateData (){QuestionType=QuestionType.SODPercent,GetDecimalNullFun=GetSODPercent},
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//与整个访视期间SOD最低点相比增加的值（mm）
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new ReadingCalculateData (){QuestionType=QuestionType.LowestIncrease,GetDecimalNullFun=GetLowestIncrease,/*ChangeAllTaskFun=ChangeAllLowestIncrease*/},
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//与整个访视期间SOD最低点相比增加的百分比
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new ReadingCalculateData (){QuestionType=QuestionType.LowPercent,GetDecimalNullFun=GetLowPercent,/*ChangeAllTaskFun=ChangeAllLowPercent*/},
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//整个访视期间SOD最低点访视名称
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new ReadingCalculateData (){QuestionType=QuestionType.LowVisit,GetStringFun=GetLowVisit,/*ChangeAllTaskFun=ChangeAllLowVisitName*/},
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//是否存在非淋巴结靶病灶
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new ReadingCalculateData (){QuestionType=QuestionType.IsLymphTarget,GetStringFun=GetIsLymphTarget},
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//是否存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上
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new ReadingCalculateData (){QuestionType=QuestionType.IsAddFive,GetStringFun=GetIsAddFive},
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//被评估为NE的单个靶病灶
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NETarget,GetStringFun=GetNETarget},
|
||
|
||
// 与前一访视SOD相比变化量
|
||
new ReadingCalculateData (){QuestionType=QuestionType.LastVisitSODChange,GetDecimalNullFun=GetLastTaskSODChange},
|
||
|
||
//新靶病灶直径之和（iSOD）
|
||
new ReadingCalculateData (){QuestionType=QuestionType.ISOD,GetDecimalNullFun=GetiSODData},
|
||
|
||
// 与前一访视相比iSOD变化量
|
||
new ReadingCalculateData (){QuestionType=QuestionType.LastVisitiSODChange,GetDecimalNullFun=GetISODChange},
|
||
|
||
// 靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.TargetLesion,GetStringFun=GetTargetLesionEvaluate,IsConvertedTask=false},
|
||
|
||
// IRECIST靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.TargetLesion,GetStringFun=GetIRECISTTargetLesionEvaluate,IsConvertedTask=true},
|
||
|
||
// 转化时靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.TargetLesion,GetStringFun=GetConvertingTargetLesionEvaluate,IsConvertedTask=true,IsBeTransforming=true},
|
||
|
||
//非靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NoTargetLesion,GetStringFun=GetNoTargetLesionEvaluate,IsConvertedTask=false},
|
||
|
||
//IRECIST非靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NoTargetLesion,GetStringFun=GetIRECISTNoTargetLesionEvaluate,IsConvertedTask=true},
|
||
|
||
// 转化时非靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NoTargetLesion,GetStringFun=GetConvertingNoTargetLesionEvaluate,IsConvertedTask=true ,IsBeTransforming=true},
|
||
|
||
// IRECIST新靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NewTargetLesion,GetStringFun=GetNewTargetLesionEvaluate,IsConvertedTask=true},
|
||
|
||
// IRECIST新非靶病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NewNoTargetLesion,GetStringFun=GetNewNoTargetLesionEvaluate,IsConvertedTask=true},
|
||
|
||
// IRECIST其它既往新病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.OtherNewTargetLesion,GetStringFun=GetOtherNewTargetLesionEvaluate,IsConvertedTask=true},
|
||
|
||
// IRECIST触发iRECIST后新病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.IRECISTNewTargetLesion,GetStringFun=GetNewLesionAfterTriggeringiRECSITAssessment,IsConvertedTask=true},
|
||
|
||
//IRECIST新病灶评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NewLesionEvaluation,GetStringFun=GetNewLesionAssessment,IsConvertedTask=true},
|
||
|
||
//是否存在新病灶
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NewLesions,GetStringFun=GetNewLesionEvaluate,IsConvertedTask=false},
|
||
|
||
// IRECIST是否存在新病灶 IRECIST
|
||
new ReadingCalculateData (){QuestionType=QuestionType.NewLesions,GetStringFun=GetNewLesionIRECSITEvaluate,IsConvertedTask=true},
|
||
|
||
//是否存在疾病
|
||
new ReadingCalculateData (){QuestionType=QuestionType.ExistDisease,GetStringFun=GetIsExistDisease},
|
||
|
||
//整体肿瘤评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.Tumor,GetStringFun=GetTumor,IsConvertedTask=false},
|
||
|
||
|
||
// 转化时整体肿瘤评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.Tumor,GetStringFun=GetConvertingTumor,IsConvertedTask=true,IsBeTransforming=true},
|
||
|
||
|
||
//IRECIST整体肿瘤评估
|
||
new ReadingCalculateData (){QuestionType=QuestionType.Tumor,GetStringFun=GetIRECSITTargetLesionEvaluate,IsConvertedTask=true},
|
||
|
||
|
||
|
||
};
|
||
|
||
// 过滤转化的
|
||
|
||
calculateList = calculateList.Where(x => x.IsConvertedTask == inDto.IsConvertedTask||x.IsConvertedTask==null).ToList();
|
||
if (inDto.IsConvertedTask)
|
||
{
|
||
|
||
|
||
if (inDto.BeforeConvertedTaskId != null)
|
||
{
|
||
List<QuestionType> questionTypes = calculateList.Where(x => x.IsBeTransforming).Select(x => x.QuestionType).ToList();
|
||
|
||
// 排除这几个 且不为正在转化的
|
||
calculateList = calculateList.Where(x => !(questionTypes.Contains(x.QuestionType)&& x.IsBeTransforming == false)).ToList();
|
||
|
||
}
|
||
else
|
||
{
|
||
calculateList = calculateList.Where(x => x.IsBeTransforming == false).ToList();
|
||
|
||
}
|
||
|
||
}
|
||
|
||
// 没有靶病灶只计算最后几个
|
||
if (inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).Sum(x => x.TableRowInfoList.Count()) == 0)
|
||
{
|
||
|
||
List<QuestionType> questionTypes = new List<QuestionType>()
|
||
{
|
||
QuestionType.TargetLesion,
|
||
QuestionType.NoTargetLesion,
|
||
QuestionType.NewLesions,
|
||
QuestionType.Tumor,
|
||
QuestionType.ExistDisease,
|
||
QuestionType.NewTargetLesion
|
||
QuestionType.NewNoTargetLesion,
|
||
QuestionType.OtherNewTargetLesion,
|
||
QuestionType.IRECISTNewTargetLesion,
|
||
QuestionType.NewLesionEvaluation,
|
||
};
|
||
|
||
// 没有靶病灶就删除其他几个答案的值
|
||
var isNeedDeleteTypes = calculateList.Where(x => !questionTypes.Contains(x.QuestionType)).Select(x => x.QuestionType).ToList();
|
||
|
||
|
||
var isNeedDeleteIds = inDto.QuestionInfo.Where(x =>x.QuestionType!=null&& isNeedDeleteTypes.Contains(x.QuestionType.Value)).Select(x => x.QuestionId).ToList();
|
||
|
||
await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => x.VisitTaskId == inDto.VisitTaskId && isNeedDeleteIds.Contains(x.ReadingQuestionTrialId), x => new ReadingTaskQuestionAnswer
|
||
{
|
||
Answer = string.Empty
|
||
});
|
||
|
||
|
||
|
||
calculateList = calculateList.Where(x => questionTypes.Contains(x.QuestionType)).ToList();
|
||
|
||
|
||
|
||
|
||
|
||
}
|
||
|
||
if (calculateType != null)
|
||
{
|
||
calculateList = calculateList.Where(x => calculateType.Contains(x.QuestionType)).ToList();
|
||
}
|
||
|
||
var typeNAList = new List<QuestionType>
|
||
{
|
||
QuestionType.SODChange,
|
||
QuestionType.SODPercent,
|
||
QuestionType.LowestIncrease,
|
||
QuestionType.LowPercent,
|
||
};
|
||
|
||
foreach (var calculate in calculateList)
|
||
{
|
||
var item = inDto.QuestionInfo.FirstOrDefault(x => x.QuestionType == calculate.QuestionType);
|
||
|
||
if (item != null)
|
||
{
|
||
//计算答案
|
||
if (inDto.IsOnlyChangeAllTask == false)
|
||
{
|
||
|
||
#region 计算答案
|
||
if (calculate.GetDecimalFun != null)
|
||
{
|
||
item.Answer = (await calculate.GetDecimalFun(inDto)).ToString();
|
||
|
||
}
|
||
else if (calculate.GetDecimalNullFun != null)
|
||
{
|
||
var value = await calculate.GetDecimalNullFun(inDto);
|
||
if (value == null)
|
||
{
|
||
if (typeNAList.Contains(item.QuestionType ?? QuestionType.SOD))
|
||
{
|
||
item.Answer = nameof(YesOrNoOrNa.NA);
|
||
|
||
}
|
||
else
|
||
{
|
||
item.Answer = this.nAString;
|
||
|
||
}
|
||
|
||
}
|
||
else
|
||
|
||
{
|
||
item.Answer = value.ToString();
|
||
}
|
||
}
|
||
else if (calculate.GetStringFun != null)
|
||
{
|
||
item.Answer = await calculate.GetStringFun(inDto);
|
||
}
|
||
#endregion
|
||
// 修改修约小数位数
|
||
|
||
List<ValueOfType?> valueOfTypes = new List<ValueOfType?>() {
|
||
|
||
ValueOfType.Decimals,
|
||
ValueOfType.Percentage
|
||
};
|
||
|
||
if (inDto.DigitPlaces != null && inDto.DigitPlaces != -1)
|
||
{
|
||
try
|
||
{
|
||
|
||
if (valueOfTypes.Contains(item.ValueType))
|
||
{
|
||
item.Answer = decimal.Round(decimal.Parse(item.Answer ?? "0"), inDto.DigitPlaces).ToString();
|
||
}
|
||
}
|
||
catch (Exception)
|
||
{
|
||
|
||
|
||
}
|
||
}
|
||
|
||
|
||
|
||
needAddList.Add(new ReadingTaskQuestionAnswer()
|
||
{
|
||
Answer = item.Answer,
|
||
ReadingQuestionTrialId = item.QuestionId,
|
||
});
|
||
}
|
||
|
||
// 修改全局
|
||
if (inDto.IsChangeOtherTask && calculate.ChangeAllTaskFun != null)
|
||
{
|
||
await calculate.ChangeAllTaskFun(new ChangeAllTaskDto()
|
||
{
|
||
calculateDto = inDto,
|
||
QuestionId = item.QuestionId,
|
||
});
|
||
}
|
||
|
||
}
|
||
}
|
||
|
||
|
||
|
||
var questionIds = needAddList.Select(x => x.ReadingQuestionTrialId).ToList();
|
||
|
||
await _readingTaskQuestionAnswerRepository.BatchDeleteNoTrackingAsync(x => questionIds.Contains(x.ReadingQuestionTrialId) && x.VisitTaskId == inDto.VisitTaskId);
|
||
needAddList.ForEach(x =>
|
||
{
|
||
x.SubjectId = inDto.SubjectId;
|
||
x.ReadingQuestionCriterionTrialId = inDto.CriterionId;
|
||
x.VisitTaskId = inDto.VisitTaskId;
|
||
x.TrialId = inDto.TrialId;
|
||
x.SubjectId = inDto.SubjectId;
|
||
});
|
||
|
||
await _readingTaskQuestionAnswerRepository.AddRangeAsync(needAddList);
|
||
|
||
await _readingTaskQuestionAnswerRepository.SaveChangesAsync();
|
||
#endregion
|
||
|
||
|
||
}
|
||
|
||
|
||
///// <summary>
|
||
///// 获取报告整体整体评估
|
||
///// </summary>
|
||
///// <param name="visitTaskId"></param>
|
||
///// <returns></returns>
|
||
//public async Task<string> GetReportTumor(Guid visitTaskId)
|
||
//{
|
||
// return await GetTumor(await _generalCalculateService.GetReadingCalculateDto(visitTaskId));
|
||
//}
|
||
|
||
/// <summary>
|
||
/// 获取报告是否存在疾病
|
||
/// </summary>
|
||
/// <param name="visitTaskId"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetReportIsExistDisease(Guid visitTaskId)
|
||
{
|
||
return await GetIsExistDisease(await _generalCalculateService.GetReadingCalculateDto(visitTaskId));
|
||
}
|
||
|
||
/// <summary>
|
||
/// 验证访视提交
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task VerifyVisitTaskQuestions(VerifyVisitTaskQuestionsInDto inDto)
|
||
{
|
||
|
||
var tableAnswerList = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.VisitTaskId && (x.Answer == string.Empty || x.Answer == null)
|
||
&& x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.State
|
||
)
|
||
.Select(x => new
|
||
{
|
||
x.ReadingQuestionTrial.OrderMark,
|
||
x.RowIndex,
|
||
QuestionMark = x.ReadingTableQuestionTrial.QuestionMark,
|
||
Answer = x.Answer,
|
||
|
||
}).ToListAsync();
|
||
|
||
|
||
string errorMassage = string.Empty;
|
||
|
||
var rowAnswerList = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == inDto.VisitTaskId && (x.MeasureData == string.Empty || x.MeasureData == null))
|
||
.Select(x => new
|
||
{
|
||
x.ReadingQuestionTrial.OrderMark,
|
||
x.RowIndex,
|
||
x.Id,
|
||
}).ToListAsync();
|
||
|
||
|
||
var unableEvaluateRowIds = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.VisitTaskId && x.Answer == TargetState.UnableEvaluate.GetEnumInt()
|
||
&& x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.State
|
||
)
|
||
.Select(x => x.RowId).Distinct().ToListAsync();
|
||
|
||
|
||
List<string> measureDataList = rowAnswerList.Where(x => !unableEvaluateRowIds.Contains(x.Id)).Select(x => x.OrderMark + x.RowIndex.GetLesionMark()).ToList();
|
||
|
||
List<string> stateIsNullList = tableAnswerList.Select(x => x.OrderMark + x.RowIndex.GetLesionMark()).ToList();
|
||
|
||
|
||
List<string> allExists = measureDataList.Intersect(stateIsNullList).ToList();
|
||
measureDataList = measureDataList.Except(allExists).ToList();
|
||
stateIsNullList = stateIsNullList.Except(allExists).ToList();
|
||
|
||
|
||
if (measureDataList.Count() > 0)
|
||
{
|
||
errorMassage += _localizer["ReadingCalculate_NoMarker", string.Join(',', measureDataList)] + ",";
|
||
}
|
||
|
||
|
||
if (tableAnswerList.Count > 0)
|
||
{
|
||
errorMassage += _localizer["ReadingCalculate_StatusIsEmpty", string.Join(',', stateIsNullList)] + ",";
|
||
}
|
||
|
||
if (allExists.Count > 0)
|
||
{
|
||
errorMassage += _localizer["ReadingCalculate_NoMarkerEmpty", string.Join(',', stateIsNullList)] + ",";
|
||
}
|
||
|
||
|
||
if (errorMassage != string.Empty)
|
||
{
|
||
errorMassage = _localizer["ReadingCalculate_Questionable"] + errorMassage;
|
||
throw new BusinessValidationFailedException(errorMassage);
|
||
}
|
||
|
||
|
||
}
|
||
|
||
|
||
|
||
#region 将上一次的访视病灶添加到这一次
|
||
|
||
/// <summary>
|
||
/// 将上一次的访视病灶添加到这一次
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<AddTaskLesionAnswerFromLastTaskOutDto> AddTaskLesionAnswerFromLastTask(AddTaskLesionAnswerFromLastTaskInDto inDto)
|
||
{
|
||
var visitTaskId = inDto.VisitTaskId;
|
||
|
||
var taskinfo = await _visitTaskRepository.Where(x => x.Id == visitTaskId).ProjectTo<VisitTaskDto>(_mapper.ConfigurationProvider).FirstNotNullAsync();
|
||
|
||
var baseLineVisitId = await _subjectVisitRepository.Where(x => x.SubjectId == taskinfo.SubjectId && x.IsBaseLine).Select(x => x.Id).FirstOrDefaultAsync();
|
||
|
||
// 判断当前任务是否是基线
|
||
if (taskinfo.SourceSubjectVisitId != baseLineVisitId)
|
||
{
|
||
|
||
// 判断当前任务是是否有表格问题答案
|
||
if (!(await _readingTableQuestionAnswerRepository.AnyAsync(x => x.VisitTaskId == visitTaskId)))
|
||
{
|
||
if (taskinfo.BeforeConvertedTaskId != null)
|
||
{
|
||
await _generalCalculateService.AddConvertedTaskFocus(taskinfo.Id, taskinfo.BeforeConvertedTaskId.Value);
|
||
}
|
||
else
|
||
{
|
||
var LastVisitTaskId = await _visitTaskRepository.Where(x => x.ReadingCategory == ReadingCategory.Visit &&
|
||
x.TrialReadingCriterionId == taskinfo.TrialReadingCriterionId &&
|
||
x.IsAnalysisCreate == taskinfo.IsAnalysisCreate &&
|
||
x.DoctorUserId == taskinfo.DoctorUserId &&
|
||
x.IsSelfAnalysis == taskinfo.IsSelfAnalysis &&
|
||
x.SubjectId == taskinfo.SubjectId && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == taskinfo.ArmEnum
|
||
&& x.VisitTaskNum < taskinfo.VisitTaskNum && x.TaskState == TaskState.Effect
|
||
).OrderByDescending(x => x.VisitTaskNum).Select(x => x.Id).FirstOrDefaultAsync();
|
||
|
||
|
||
|
||
var copyTableAnswers = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == LastVisitTaskId).Select(x => new CopyTableAnswerDto()
|
||
{
|
||
Answer = x.Answer,
|
||
QuestionId = x.QuestionId,
|
||
RowId = x.RowId,
|
||
QuestionMark = x.ReadingTableQuestionTrial.QuestionMark,
|
||
TableQuestionId = x.TableQuestionId,
|
||
RowIndex = x.RowIndex,
|
||
TrialId = x.TrialId
|
||
}).ToListAsync();
|
||
|
||
var tableRowAnswers = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == LastVisitTaskId).ProjectTo<CopyTableAnswerRowInfo>(_mapper.ConfigurationProvider).ToListAsync();
|
||
|
||
|
||
tableRowAnswers.ForEach(x =>
|
||
{
|
||
x.VisitTaskId = visitTaskId;
|
||
x.IsCurrentTaskAdd = false;
|
||
x.Id = NewId.NextGuid();
|
||
x.SeriesId = null;
|
||
x.InstanceId = null;
|
||
x.MeasureData = string.Empty;
|
||
x.PicturePath = string.Empty;
|
||
});
|
||
|
||
tableRowAnswers.ForEach(x =>
|
||
{
|
||
x.SplitRowId = tableRowAnswers.Where(y => y.OriginalId == x.SplitRowId).Select(y => y.Id).FirstOrDefault();
|
||
x.MergeRowId = tableRowAnswers.Where(y => y.OriginalId == x.MergeRowId).Select(y => y.Id).FirstOrDefault();
|
||
|
||
});
|
||
|
||
List<QuestionMark?> notNeedCopyMarks = new List<QuestionMark?>()
|
||
{
|
||
QuestionMark.MajorAxis,
|
||
QuestionMark.ShortAxis,
|
||
QuestionMark.State,
|
||
};
|
||
|
||
//if (taskinfo.IsConvertedTask)
|
||
//{
|
||
// notNeedCopyMarks = new List<QuestionMark?>()
|
||
//{
|
||
// QuestionMark.MajorAxis,
|
||
// QuestionMark.ShortAxis,
|
||
//};
|
||
//}
|
||
|
||
var tableAnswers = copyTableAnswers.Select(x => new ReadingTableQuestionAnswer
|
||
{
|
||
Id = NewId.NextGuid(),
|
||
Answer = notNeedCopyMarks.Contains(x.QuestionMark) ? string.Empty : x.Answer,
|
||
QuestionId = x.QuestionId,
|
||
RowIndex = x.RowIndex,
|
||
RowId = tableRowAnswers.Where(y => y.OriginalId == x.RowId).Select(x => x.Id).FirstOrDefault(),
|
||
TableQuestionId = x.TableQuestionId,
|
||
TrialId = x.TrialId,
|
||
VisitTaskId = visitTaskId,
|
||
});
|
||
|
||
|
||
|
||
|
||
var addList = _mapper.Map<List<ReadingTableAnswerRowInfo>>(tableRowAnswers);
|
||
|
||
await _readingTableAnswerRowInfoRepository.AddRangeAsync(addList);
|
||
await _readingTableQuestionAnswerRepository.AddRangeAsync(tableAnswers);
|
||
await _readingTableQuestionAnswerRepository.SaveChangesAsync();
|
||
}
|
||
|
||
|
||
}
|
||
}
|
||
|
||
return new AddTaskLesionAnswerFromLastTaskOutDto()
|
||
{
|
||
|
||
IsBaseLine = taskinfo.SourceSubjectVisitId == baseLineVisitId,
|
||
};
|
||
|
||
}
|
||
#endregion
|
||
|
||
#region 获取SOD
|
||
|
||
/// <summary>
|
||
/// 获取SOD
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// 靶病灶径线之和（SOD）
|
||
/// 非淋巴结的长径 和淋巴结的短径
|
||
/// </remarks>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetSODData(ReadingCalculateDto inDto)
|
||
{
|
||
if (sODData != null)
|
||
{
|
||
return sODData.Value;
|
||
}
|
||
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
if (tableQuestion.Count() == 0)
|
||
{
|
||
return null;
|
||
}
|
||
|
||
decimal result = 0;
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
|
||
{
|
||
// 淋巴结的短径
|
||
result += (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0();
|
||
}
|
||
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.No)))
|
||
{
|
||
// 非淋巴结的长径
|
||
result += item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
|
||
}
|
||
}
|
||
|
||
sODData = result;
|
||
|
||
return sODData.Value;
|
||
|
||
|
||
|
||
}
|
||
#endregion
|
||
|
||
#region 非淋巴结靶病灶长径之和
|
||
/// <summary>
|
||
/// 非淋巴结靶病灶长径之和
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetSumOfDiameter(ReadingCalculateDto inDto)
|
||
{
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
if (tableQuestion.Count() == 0)
|
||
{
|
||
return null;
|
||
}
|
||
|
||
decimal result = 0;
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.No)))
|
||
{
|
||
// 非淋巴结的长径
|
||
result += item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
|
||
}
|
||
}
|
||
|
||
|
||
return result;
|
||
}
|
||
#endregion
|
||
|
||
#region 与基线SOD相比变化量（mm）
|
||
/// <summary>
|
||
/// 与基线SOD相比变化量（mm）
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetSODChange(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
var value = await GetSODData(inDto);
|
||
|
||
if (value == null || inDto.IsBaseLine)
|
||
{
|
||
return null;
|
||
}
|
||
return value.NullChange0() - await GetBaseLineSOD(inDto);
|
||
}
|
||
#endregion
|
||
|
||
#region 与基线访视相比SOD变化百分比
|
||
/// <summary>
|
||
/// 与基线访视相比SOD变化百分比
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetSODPercent(ReadingCalculateDto inDto)
|
||
{
|
||
var thisSOD = await GetSODData(inDto);
|
||
|
||
if (thisSOD == null || inDto.IsBaseLine)
|
||
{
|
||
return null;
|
||
}
|
||
|
||
var baseLineSOD = await GetBaseLineSOD(inDto);
|
||
|
||
if (baseLineSOD == 0)
|
||
{
|
||
return 100;
|
||
}
|
||
else
|
||
{
|
||
return (thisSOD.NullChange0() - baseLineSOD) * 100 / baseLineSOD;
|
||
}
|
||
}
|
||
#endregion
|
||
|
||
#region 与整个访视期间SOD最低点相比增加的值（mm）
|
||
/// <summary>
|
||
/// 与整个访视期间SOD最低点相比增加的值（mm）
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <remarks>
|
||
/// 要更新之前的
|
||
/// </remarks>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetLowestIncrease(ReadingCalculateDto inDto)
|
||
{
|
||
var value = await GetSODData(inDto);
|
||
if (value == null || inDto.IsBaseLine)
|
||
{
|
||
return null;
|
||
}
|
||
var decimalAnswerList = await GetLowSODVisit(inDto);
|
||
var minSOD = decimalAnswerList.OrderBy(x => x.SOD).Select(x => x.SOD).FirstOrDefault();
|
||
return value.NullChange0() - minSOD;
|
||
}
|
||
#endregion
|
||
|
||
#region 与整个访视期间SOD最低点相比增加的百分比
|
||
/// <summary>
|
||
/// 与整个访视期间SOD最低点相比增加的百分比
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <remarks>
|
||
/// 要更新之前的
|
||
/// </remarks>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetLowPercent(ReadingCalculateDto inDto)
|
||
{
|
||
var thisSOD = await GetSODData(inDto);
|
||
if (thisSOD == null || inDto.IsBaseLine)
|
||
{
|
||
return null;
|
||
}
|
||
var decimalAnswerList = await GetLowSODVisit(inDto);
|
||
var minSOD = decimalAnswerList.OrderBy(x => x.SOD).Select(x => x.SOD).FirstOrDefault();
|
||
|
||
if (minSOD == 0)
|
||
{
|
||
return 100;
|
||
}
|
||
else
|
||
{
|
||
return (thisSOD.NullChange0() - minSOD) * 100 / minSOD;
|
||
}
|
||
|
||
|
||
}
|
||
#endregion
|
||
|
||
#region 整个访视期间SOD最低点访视名称
|
||
/// <summary>
|
||
/// 整个访视期间SOD最低点访视名称
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <remarks>
|
||
/// 要更新之前的
|
||
/// </remarks>
|
||
/// <returns></returns>
|
||
public async Task<string> GetLowVisit(ReadingCalculateDto inDto)
|
||
{
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return nameof(YesOrNoOrNa.NA);
|
||
}
|
||
var targetCount = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).Count();
|
||
if (targetCount == 0)
|
||
{
|
||
return nameof(YesOrNoOrNa.NA);
|
||
}
|
||
|
||
var decimalAnswerList = await GetLowSODVisit(inDto);
|
||
return decimalAnswerList.OrderBy(x => x.SOD).Select(x => x.BlindName).FirstOrDefault() ?? string.Empty;
|
||
}
|
||
#endregion
|
||
|
||
#region 是否存在非淋巴结靶病灶
|
||
/// <summary>
|
||
/// 是否存在非淋巴结靶病灶
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetIsLymphTarget(ReadingCalculateDto inDto)
|
||
{
|
||
var result = IsLymph.No.GetEnumInt();
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(IsLymph.No)))
|
||
{
|
||
result = IsLymph.Yes.GetEnumInt();
|
||
}
|
||
}
|
||
|
||
|
||
|
||
return result;
|
||
}
|
||
#endregion
|
||
|
||
#region 是否存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上
|
||
/// <summary>
|
||
/// 是否存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetIsAddFive(ReadingCalculateDto inDto)
|
||
{
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return YesOrNoOrNa.NA.GetEnumInt();
|
||
}
|
||
var addFiveList = await GetIsAddFiveRowIndexs(inDto);
|
||
var isExists = addFiveList.Count() > 0 ? true : false;
|
||
|
||
return isExists ? YesOrNoOrNa.Yes.GetEnumInt() : YesOrNoOrNa.No.GetEnumInt();
|
||
|
||
}
|
||
|
||
/// <summary>
|
||
/// 获取存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上的病灶
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<List<decimal>> GetIsAddFiveRowIndexs(ReadingCalculateDto inDto)
|
||
{
|
||
List<decimal> result = new List<decimal>();
|
||
var LastVisitTaskId = await this.GetLastVisitTaskId(inDto);
|
||
var questionIds = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).Select(x => x.QuestionId).ToList();
|
||
var lastQuestionAsnwer = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == LastVisitTaskId && questionIds.Contains(x.QuestionId)).Include(x => x.ReadingQuestionTrial).Include(x => x.ReadingTableQuestionTrial).ToListAsync();
|
||
var rowIndexs = lastQuestionAsnwer.Where(x => x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)).Select(x => x.RowIndex).Distinct().OrderBy(x => x).ToList();
|
||
var thisQuestionAsnwer = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
foreach (var item in rowIndexs)
|
||
{
|
||
var lastValue = lastQuestionAsnwer.Where(x => x.RowIndex == item && x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
|
||
|
||
var thisRowData = thisQuestionAsnwer.Where(x => x.RowIndex == item).SelectMany(x => x.TableQuestionList).ToList();
|
||
var thisValue = thisRowData.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
|
||
|
||
if (thisValue - lastValue >= 5)
|
||
{
|
||
result.Add(item);
|
||
}
|
||
}
|
||
|
||
return result;
|
||
}
|
||
#endregion
|
||
|
||
#region 被评估为NE的单个靶病灶
|
||
/// <summary>
|
||
/// 被评估为NE的单个靶病灶
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNETarget(ReadingCalculateDto inDto)
|
||
{
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return ExistOrNA.NA.GetEnumInt();
|
||
}
|
||
|
||
var result = inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.NE));
|
||
|
||
return result ? ExistOrNA.Exist.GetEnumInt() : ExistOrNA.NotExist.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region 整体肿瘤评估
|
||
|
||
/// <summary>
|
||
/// 整体肿瘤评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetTumor(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return OverallAssessment.NA.GetEnumInt();
|
||
}
|
||
|
||
var targetLesion = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.TargetLesion).Select(x => x.Answer).FirstOrDefault();
|
||
var noTargetLesion = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NoTargetLesion).Select(x => x.Answer).FirstOrDefault();
|
||
var newLesions = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewLesions).Select(x => x.Answer).FirstOrDefault();
|
||
var result = await _tumorAssessmentRepository.Where(x =>
|
||
x.TargetLesion == (TargetAssessment)int.Parse(targetLesion.IsNullOrEmpty() ? TargetAssessment.NA.GetEnumInt() : targetLesion) &&
|
||
x.NonTargetLesions == (NoTargetAssessment)int.Parse(noTargetLesion.IsNullOrEmpty() ? NoTargetAssessment.NA.GetEnumInt() : noTargetLesion) &&
|
||
x.NewLesion == (NewLesionAssessment)int.Parse(newLesions.IsNullOrEmpty() ? NewLesionAssessment.NA.GetEnumInt() : newLesions)).Select(x => x.OverallEfficacy).ToListAsync();
|
||
|
||
return result.Count == 0 ? OverallAssessment.NE.GetEnumInt() : result[0].GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region 是否存在疾病
|
||
/// <summary>
|
||
/// 是否存在疾病
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetIsExistDisease(ReadingCalculateDto inDto)
|
||
{
|
||
if (!inDto.IsBaseLine)
|
||
{
|
||
return string.Empty;
|
||
}
|
||
|
||
var lesionCount = inDto.QuestionInfo.SelectMany(x => x.TableRowInfoList).Count();
|
||
|
||
return lesionCount > 0 ? ExistDisease.Yes.GetEnumInt() : ExistDisease.No.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region 与前一访视SOD相比变化量
|
||
/// <summary>
|
||
/// 与前一访视SOD相比变化量
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetLastTaskSODChange(ReadingCalculateDto inDto)
|
||
{
|
||
var lastTaskId = await this.GetLastVisitTaskId(inDto);
|
||
var lastSOD = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.SOD).Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0();
|
||
|
||
var value = await GetSODData(inDto);
|
||
|
||
if (value == null || inDto.IsBaseLine)
|
||
{
|
||
return null;
|
||
}
|
||
return value.NullChange0() - lastSOD;
|
||
}
|
||
#endregion
|
||
|
||
#region 新靶病灶直径之和（iSOD）
|
||
|
||
/// <summary>
|
||
/// 获取iSOD
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetiSODData(ReadingCalculateDto inDto)
|
||
{
|
||
if (iSODData != null)
|
||
{
|
||
return iSODData.Value;
|
||
}
|
||
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
if (tableQuestion.Count() == 0)
|
||
{
|
||
return null;
|
||
}
|
||
|
||
decimal result = 0;
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
|
||
{
|
||
// 淋巴结的短径
|
||
result += (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0();
|
||
}
|
||
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.No)))
|
||
{
|
||
// 非淋巴结的长径
|
||
result += item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
|
||
}
|
||
}
|
||
|
||
iSODData = result;
|
||
|
||
return iSODData.Value;
|
||
|
||
|
||
|
||
}
|
||
#endregion
|
||
|
||
#region 与前一访视相比iSOD变化量
|
||
|
||
/// <summary>
|
||
/// 与前一访视相比iSOD变化量
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<decimal?> GetISODChange(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
var lastTaskId = await this.GetLastVisitTaskId(inDto);
|
||
var lastiSOD = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.ISOD).Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0();
|
||
|
||
var value = await GetiSODData(inDto);
|
||
|
||
if (value == null || inDto.IsBaseLine)
|
||
{
|
||
return null;
|
||
}
|
||
return value.NullChange0() - lastiSOD;
|
||
}
|
||
#endregion
|
||
|
||
#region 修改其他标准
|
||
|
||
#region 修改与整个访视期间SOD最低点相比增加的值（mm）
|
||
|
||
/// <summary>
|
||
/// 修改与整个访视期间SOD最低点相比增加的值（mm）
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task ChangeAllLowestIncrease(ChangeAllTaskDto inDto)
|
||
{
|
||
var visitTaskList = await GetVisitTaskAnswerList(inDto.calculateDto);
|
||
|
||
var lowSod = (await GetLowSODVisit(inDto.calculateDto)).Select(x => x.SOD).OrderBy(x => x).FirstOrDefault();
|
||
|
||
foreach (var item in visitTaskList.Where(x => x.VisitTaskId != inDto.calculateDto.BaseLineTaskId))
|
||
{
|
||
await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => x.VisitTaskId == item.VisitTaskId && x.ReadingQuestionTrialId == inDto.QuestionId, x => new ReadingTaskQuestionAnswer()
|
||
{
|
||
Answer = (item.SOD - lowSod).ToString()
|
||
});
|
||
}
|
||
}
|
||
|
||
#endregion
|
||
|
||
|
||
#region 修改整个访视期间SOD最低点相比增加的百分比
|
||
|
||
/// <summary>
|
||
/// 修改整个访视期间SOD最低点相比增加的百分比
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
//public async Task ChangeAllLowPercent(ChangeAllTaskDto inDto)
|
||
//{
|
||
// var visitTaskList = await GetVisitTaskAnswerList(inDto.calculateDto);
|
||
|
||
// var lowSod = (await GetLowSODVisit(inDto.calculateDto)).Select(x => x.SOD).OrderBy(x => x).FirstOrDefault();
|
||
|
||
// foreach (var item in visitTaskList.Where(x => x.VisitTaskId != inDto.calculateDto.BaseLineTaskId))
|
||
// {
|
||
// decimal percent = 0;
|
||
// if (lowSod == 0)
|
||
// {
|
||
// percent = 100;
|
||
// }
|
||
// else
|
||
// {
|
||
// percent = decimal.Round((item.SOD - lowSod) * 100 / lowSod, 2);
|
||
// }
|
||
|
||
// await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => x.VisitTaskId == item.VisitTaskId && x.ReadingQuestionTrialId == inDto.QuestionId, x => new ReadingTaskQuestionAnswer()
|
||
// {
|
||
// Answer = percent.ToString()
|
||
// });
|
||
// }
|
||
//}
|
||
|
||
#endregion
|
||
|
||
#region 修改最低方式点名称
|
||
/// <summary>
|
||
/// 修改最低方式点名称
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task ChangeAllLowVisitName(ChangeAllTaskDto inDto)
|
||
{
|
||
// 找到所有访视任务的Id
|
||
|
||
var visitTaskIds = await _visitTaskRepository.Where(x => x.IsAnalysisCreate == inDto.IsAnalysisCreate &&
|
||
x.ReadingCategory == ReadingCategory.Visit &&
|
||
x.TrialReadingCriterionId == inDto.calculateDto.TrialReadingCriterionId &&
|
||
x.TaskState == TaskState.Effect && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == inDto.calculateDto.ArmEnum).Select(x => x.Id).ToListAsync();
|
||
|
||
var answer = (await GetLowSODVisit(inDto.calculateDto)).OrderBy(x => x.SOD).Select(x => x.BlindName).FirstOrDefault();
|
||
visitTaskIds = visitTaskIds.Where(x => x != inDto.calculateDto.BaseLineTaskId).ToList();
|
||
await this.ChangeAllVisitTaskAnswer(visitTaskIds, inDto.QuestionId, answer);
|
||
|
||
}
|
||
#endregion
|
||
|
||
|
||
#endregion
|
||
|
||
#region 通用方法
|
||
|
||
#region 修改所有访视任务的答案
|
||
/// <summary>
|
||
/// 修改所有访视任务的答案
|
||
/// </summary>
|
||
/// <param name="visitTaskGuids"></param>
|
||
/// <param name="questionId"></param>
|
||
/// <param name="answer"></param>
|
||
/// <returns></returns>
|
||
private async Task ChangeAllVisitTaskAnswer(List<Guid> visitTaskGuids, Guid questionId, string answer)
|
||
{
|
||
await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => visitTaskGuids.Contains(x.VisitTaskId) && x.ReadingQuestionTrialId == questionId, x => new ReadingTaskQuestionAnswer()
|
||
{
|
||
Answer = answer
|
||
});
|
||
}
|
||
#endregion
|
||
|
||
|
||
#region 获取基线SOD
|
||
/// <summary>
|
||
/// 获取基线SOD
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
private async Task<decimal> GetBaseLineSOD(ReadingCalculateDto inDto)
|
||
{
|
||
if (await _visitTaskRepository.AnyAsync(x => x.Id == inDto.VisitTaskId && x.SourceSubjectVisit.IsBaseLine && x.IsAnalysisCreate==inDto.IsAnalysisCreate && x.ArmEnum == inDto.ArmEnum))
|
||
{
|
||
return 0;
|
||
}
|
||
|
||
// 先找到基线的任务
|
||
var baseLineTaskId = await _visitTaskRepository.Where(x => x.SubjectId == inDto.SubjectId && x.ReadingCategory == ReadingCategory.Visit
|
||
&& x.TrialReadingCriterionId == inDto.TrialReadingCriterionId &&
|
||
|
||
x.SourceSubjectVisit.IsBaseLine && x.TaskState == TaskState.Effect &&
|
||
x.IsAnalysisCreate == inDto.IsAnalysisCreate
|
||
&&x.DoctorUserId==inDto.DoctorUserId
|
||
&& x.IsSelfAnalysis == inDto.IsSelfAnalysis && x.ArmEnum == inDto.ArmEnum)
|
||
.Select(x => x.Id).FirstOrDefaultAsync();
|
||
|
||
|
||
var baseLineSOD = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == baseLineTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.SOD).Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0();
|
||
return baseLineSOD;
|
||
}
|
||
#endregion
|
||
|
||
|
||
/// <summary>
|
||
/// 获取最低方式
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<List<VisitTaskAnswerInfo>> GetLowSODVisit(ReadingCalculateDto inDto)
|
||
{
|
||
var taskAnswerList = await GetVisitTaskAnswerList(inDto);
|
||
|
||
taskAnswerList = taskAnswerList.Where(x => x.VisitTaskId != inDto.VisitTaskId).ToList();
|
||
|
||
var taskIds = taskAnswerList.Select(x => x.VisitTaskId).ToList();
|
||
|
||
// 排除无法评估
|
||
var unableEvaluateTaskIds = await _readingTableQuestionAnswerRepository.Where(x => taskIds.Contains(x.VisitTaskId) &&
|
||
x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.State
|
||
&& x.ReadingQuestionTrial.LesionType == LesionType.TargetLesion
|
||
&& x.Answer == TargetState.UnableEvaluate.GetEnumInt()
|
||
)
|
||
.Select(x => x.VisitTaskId).Distinct().ToListAsync();
|
||
|
||
taskAnswerList = taskAnswerList.Where(x => !unableEvaluateTaskIds.Contains(x.VisitTaskId)).ToList();
|
||
return taskAnswerList.OrderBy(x => x.SOD).ToList();
|
||
}
|
||
|
||
#region 获取访视任务信息
|
||
/// <summary>
|
||
/// 获取访视任务信息
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<List<VisitTaskAnswerInfo>> GetVisitTaskAnswerList(ReadingCalculateDto inDto)
|
||
{
|
||
if (visitTaskAnswerList == null)
|
||
{
|
||
// 查询的时候要把自己排除 因为查询出来的可能不是计算出的最新的
|
||
visitTaskAnswerList = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId != inDto.VisitTaskId && x.VisitTask.ReadingCategory == ReadingCategory.Visit
|
||
&& x.VisitTask.IsAnalysisCreate == inDto.IsAnalysisCreate
|
||
&& x.VisitTask.IsSelfAnalysis == inDto.IsSelfAnalysis
|
||
&& x.ReadingQuestionCriterionTrialId == inDto.TrialReadingCriterionId
|
||
&& x.VisitTask.VisitTaskNum<inDto.VisitTaskNum
|
||
&& x.SubjectId == inDto.SubjectId && x.VisitTask.ReadingTaskState == ReadingTaskState.HaveSigned && x.VisitTask.ArmEnum == inDto.ArmEnum && x.VisitTask.TaskState == TaskState.Effect && x.ReadingQuestionTrial.QuestionType == QuestionType.SOD)
|
||
.Select(x => new VisitTaskAnswerInfo
|
||
{
|
||
VisitTaskId = x.VisitTaskId,
|
||
QuestionId = x.ReadingQuestionTrialId,
|
||
VisitName = x.VisitTask.SourceSubjectVisit.VisitName,
|
||
BlindName = x.VisitTask.TaskBlindName,
|
||
|
||
SOD = x.Answer.IsNullOrEmptyReturn0(),
|
||
}).ToListAsync();
|
||
|
||
// 这里是需要加上自己的 基线不用管
|
||
if (visitTaskAnswerList.Count > 0)
|
||
{
|
||
visitTaskAnswerList.Add(new VisitTaskAnswerInfo()
|
||
{
|
||
VisitTaskId = inDto.VisitTaskId,
|
||
BlindName=inDto.TaskBlindName,
|
||
QuestionId = visitTaskAnswerList[0].QuestionId,
|
||
VisitName = inDto.VisitName,
|
||
SOD = (await GetSODData(inDto)).ToString().IsNullOrEmptyReturn0(),
|
||
});
|
||
}
|
||
|
||
|
||
}
|
||
|
||
return visitTaskAnswerList;
|
||
}
|
||
#endregion
|
||
|
||
/// <summary>
|
||
/// 获取上一个访视任务Id
|
||
/// </summary>
|
||
/// <returns></returns>
|
||
private async Task<Guid> GetLastVisitTaskId(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
if (lastVisitTaskId != null)
|
||
{
|
||
return lastVisitTaskId.Value;
|
||
}
|
||
else
|
||
{
|
||
var taskinfo = await _visitTaskRepository.Where(x => x.Id == inDto.VisitTaskId).ProjectTo<VisitTaskDto>(_mapper.ConfigurationProvider).FirstNotNullAsync();
|
||
var lastTaskId = await _visitTaskRepository.Where(x => x.ReadingCategory == ReadingCategory.Visit &&
|
||
x.TrialReadingCriterionId == taskinfo.TrialReadingCriterionId &&
|
||
x.IsAnalysisCreate == taskinfo.IsAnalysisCreate &&
|
||
x.DoctorUserId == taskinfo.DoctorUserId &&
|
||
x.IsSelfAnalysis == taskinfo.IsSelfAnalysis &&
|
||
x.SubjectId == taskinfo.SubjectId && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == taskinfo.ArmEnum
|
||
&& x.VisitTaskNum < taskinfo.VisitTaskNum && x.TaskState == TaskState.Effect
|
||
).OrderByDescending(x => x.VisitTaskNum).Select(x => x.Id).FirstOrDefaultAsync();
|
||
lastVisitTaskId = lastTaskId;
|
||
return lastTaskId;
|
||
}
|
||
|
||
|
||
|
||
|
||
}
|
||
#endregion
|
||
|
||
#region 计算阅片问题 外层问题
|
||
|
||
#region IRECIST计算
|
||
|
||
#region 获取IRECIST靶病灶评估
|
||
|
||
/// <summary>
|
||
/// 获取IRECIST靶病灶评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <remarks>
|
||
/// if（基线没有靶病灶）
|
||
/// {
|
||
/// 靶病灶疗效为 ND
|
||
/// }
|
||
/// else if (上一访视评估为iCPD && 本次访视满足RECIST1.1的PD条件&&比整体访视期间最低点SOD增加≥20%&&比整体访视期间最低点SOD绝对增加值≥5 mm)
|
||
/// {
|
||
/// 靶病灶疗效为 ICPD
|
||
/// }
|
||
/// else if (上一访视评估为iUPD&&本次访视SOD增加不小于5mm)
|
||
/// {
|
||
/// 靶病灶疗效为 ICPD
|
||
/// }
|
||
/// else if (本次访视满足RECIST1.1的PD条件 && (比整体访视期间最低点SOD增加≥20 % && 比整体访视期间最低点SOD绝对增加值≥5 mm)|| (前一访视评估为iCR && 当前访视至少有一个“存在”状态的靶病灶))
|
||
/// {
|
||
/// 靶病灶疗效为 iUPD
|
||
/// } else if (有任一靶病灶为NE状态)
|
||
/// {
|
||
/// 靶病灶疗效为 NE
|
||
/// }
|
||
/// else if (所有非淋巴结靶病灶消失，径线总和为0 mm && 所有淋巴结靶病灶的短径缩小到 < 10 mm)
|
||
/// {
|
||
/// 靶病灶疗效为 iCR
|
||
/// } else if (与基线期SOD相比减小≥30 %)
|
||
/// {
|
||
/// 靶病灶疗效为 iPR
|
||
/// }
|
||
/// else
|
||
/// {
|
||
/// 靶病灶疗效为 iSD
|
||
/// }
|
||
///
|
||
/// </remarks>
|
||
/// <returns></returns>
|
||
public async Task<string> GetIRECISTTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
var targetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.TargetLesion).Select(x => x.QuestionId).FirstOrDefault();
|
||
|
||
var sodQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SOD).Select(x => x.QuestionId).FirstOrDefault();
|
||
IRECISTTargetLesionDto resultData = new IRECISTTargetLesionDto()
|
||
{
|
||
// 基线没有靶病灶
|
||
NotExistsTargetLesion = tableQuestion.Count() == 0,
|
||
|
||
// 上一访视评估
|
||
LastTaskTarget = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == targetLesionQuestionId)
|
||
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
|
||
|
||
// 满足RECISTPD
|
||
MeetRECISTPD = (await GetTargetLesionEvaluate(inDto)) == TargetAssessment.PD.GetEnumInt(),
|
||
|
||
// 本次访视SOD增加不小于5mm
|
||
SODAddGreaterThan5 = await GetSODData(inDto) - (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == sodQuestionId)
|
||
.Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0() >= 5,
|
||
|
||
//比整体访视期间最低点SOD增加≥20 %
|
||
LowSodAddGreaterThan20Percent = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 20,
|
||
|
||
// 比整体访视期间最低点SOD绝对增加值≥5 mm
|
||
LowSodAddGreaterThan5 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowestIncrease).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 5,
|
||
|
||
// 当前访视至少有一个“存在”状态的靶病灶
|
||
HaveExistLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.Exist)),
|
||
|
||
// 有任一靶病灶为NE状态
|
||
HaveNeLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.UnableEvaluate)),
|
||
|
||
// 所有非淋巴结靶病灶消失，径线总和为0
|
||
AllLesionVanish = true,
|
||
|
||
// 所有淋巴结靶病灶的短径缩小到 < 10 mm
|
||
AllMinorAxisLessThan10 = true,
|
||
|
||
// 与基线期SOD相比减小≥30 %
|
||
BaseLineLessThan30 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) <= -30,
|
||
};
|
||
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
|
||
{
|
||
// 淋巴结的短径
|
||
resultData.AllMinorAxisLessThan10 = resultData.AllMinorAxisLessThan10 && (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() < 10;
|
||
|
||
|
||
}
|
||
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && !x.Answer.EqEnum(YesOrNoOrNa.Yes)))
|
||
{
|
||
resultData.AllLesionVanish = resultData.AllLesionVanish && item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.State).Select(x => x.Answer).FirstOrDefault() == TargetState.Loss.GetEnumInt();
|
||
}
|
||
}
|
||
TargetAssessment result = TargetAssessment.SD;
|
||
|
||
// if（基线没有靶病灶）
|
||
if (resultData.NotExistsTargetLesion)
|
||
{
|
||
// 靶病灶疗效为 ND
|
||
result = TargetAssessment.ND;
|
||
}
|
||
// else if (上一访视评估为iCPD && 本次访视满足RECIST1.1的PD条件&&比整体访视期间最低点SOD增加≥20%&&比整体访视期间最低点SOD绝对增加值≥5 mm)
|
||
else if (resultData.LastTaskTarget.EqEnum(TargetAssessment.iCPD) && resultData.MeetRECISTPD && resultData.LowSodAddGreaterThan20Percent && resultData.LowSodAddGreaterThan5)
|
||
{
|
||
// 靶病灶疗效为 ICPD
|
||
result = TargetAssessment.iCPD;
|
||
}
|
||
// else if (上一访视评估为iUPD&&本次访视SOD增加不小于5mm)
|
||
else if (resultData.LastTaskTarget.EqEnum(TargetAssessment.iUPD) && resultData.SODAddGreaterThan5)
|
||
{
|
||
// 靶病灶疗效为 ICPD
|
||
result = TargetAssessment.iCPD;
|
||
}
|
||
// } else if (本次访视满足RECIST1.1的PD条件 && (比整体访视期间最低点SOD增加≥20 % && 比整体访视期间最低点SOD绝对增加值≥5 mm)|| (前一访视评估为iCR && 当前访视至少有一个“存在”状态的靶病灶))
|
||
else if (resultData.MeetRECISTPD && (resultData.LowSodAddGreaterThan20Percent && resultData.LowSodAddGreaterThan5) || (resultData.LastTaskTarget.EqEnum(TargetAssessment.iCR) && resultData.HaveExistLesion))
|
||
{
|
||
// 靶病灶疗效为 iUPD
|
||
result = TargetAssessment.iUPD;
|
||
}
|
||
// else if (有任一靶病灶为NE状态)
|
||
else if(resultData.HaveNeLesion)
|
||
{
|
||
// 靶病灶疗效为 NE
|
||
result = TargetAssessment.NE;
|
||
}
|
||
// else if (所有非淋巴结靶病灶消失，径线总和为0 mm && 所有淋巴结靶病灶的短径缩小到 < 10 mm)
|
||
else if(resultData.AllLesionVanish&&resultData.AllMinorAxisLessThan10)
|
||
{
|
||
// 靶病灶疗效为 iCR
|
||
result = TargetAssessment.iCR;
|
||
}
|
||
// else if (与基线期SOD相比减小≥30 %)
|
||
else if(resultData.BaseLineLessThan30)
|
||
{
|
||
// 靶病灶疗效为 iPR
|
||
result = TargetAssessment.iPR;
|
||
}
|
||
// else
|
||
else
|
||
{
|
||
// 靶病灶疗效为 iSD
|
||
result = TargetAssessment.iSD;
|
||
}
|
||
|
||
|
||
return result.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region IRECIST非靶病灶评估
|
||
|
||
/// <summary>
|
||
/// IRECIST非靶病灶评估
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// if（基线没有非靶病灶）
|
||
/// {
|
||
/// 非靶病灶疗效为 ND
|
||
/// }
|
||
/// else if (上次非靶病灶评估结果为非iUPD && (任一非靶病灶状态评估为“进一步增大（iCPD）||出现至少1个上一访视未评估为“显著增大（iUPD）”的病灶本次访视评估为“显著增大（iUPD）”))
|
||
/// {
|
||
/// 非靶病灶疗效为 iCPD
|
||
/// }
|
||
/// else if (上次非靶病灶评估结果为非iCPD && 任一非靶病灶状态评估为“进一步增大（iCPD）”或“显著增大（iUPD）”)
|
||
/// {
|
||
/// 非靶病灶疗效为 iCPD
|
||
/// }
|
||
/// else if (满足RECIST1.1的PD标准 && 任一非靶病灶状态评估为“显著增大（iUPD）”)
|
||
/// {
|
||
/// 非靶病灶疗效为 iUPD
|
||
/// }
|
||
/// else if (有任一非靶病灶为NE状态)
|
||
/// {
|
||
/// 非靶病灶疗效为 NE
|
||
/// }
|
||
/// else if (全部非靶病灶均为“消失”状态)
|
||
/// {
|
||
/// 非靶病灶疗效为 iCR
|
||
/// }
|
||
/// else
|
||
/// {
|
||
/// 非靶病灶疗效为 iNN
|
||
/// }
|
||
/// </remarks>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetIRECISTNoTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList).ToList();
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
var noTargetQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NoTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
|
||
|
||
// 找上一次任务 未被评为显著增大的非靶病灶
|
||
ReadingCalculateDto lastTaskCalculateDto = await _generalCalculateService.GetReadingCalculateDto(lastVisitTaskId);
|
||
|
||
var lastTaskNoiUPDIndexs = lastTaskCalculateDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList)
|
||
.Where(x => x.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && !x.Answer.EqEnum(NoTargetState.IUPD))).Select(x => x.RowIndex).ToList();
|
||
|
||
|
||
IRECISTNoTargetLesion data = new IRECISTNoTargetLesion()
|
||
{
|
||
// 基线没有非靶病灶
|
||
NotExistsNoTargetLesion = tableQuestion.Count() == 0,
|
||
|
||
// 上次非靶病灶评估结果
|
||
LastNoTargetLesion = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == noTargetQuestionId)
|
||
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
|
||
|
||
// 任一非靶病灶状态评估为“进一步增大（iCPD）”
|
||
ExistiCPD = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.ICPD)),
|
||
|
||
// 出现至少1个上一访视未评估为“显著增大（iUPD）”的病灶本次访视评估为“显著增大（iUPD）”
|
||
LastNoUPD = tableQuestion.Where(x => lastTaskNoiUPDIndexs.Contains(x.RowIndex)).SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.IUPD)),
|
||
|
||
// 任一非靶病灶状态评估为 iUPD
|
||
ExistiUPD = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.IUPD)),
|
||
|
||
// 满足RECIST1.1PD
|
||
RECISTPD = (await GetNoTargetLesionEvaluate(inDto)).EqEnum(NoTargetAssessment.PD),
|
||
|
||
// 有任一非靶病灶为NE状态
|
||
HaveNeLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.UnableEvaluate)),
|
||
|
||
// 全部为消失
|
||
AllVanish = true,
|
||
};
|
||
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
data.AllVanish = data.AllVanish && item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Loss));
|
||
}
|
||
|
||
NoTargetAssessment result = NoTargetAssessment.iNN;
|
||
|
||
// if（基线没有非靶病灶）
|
||
if (data.NotExistsNoTargetLesion)
|
||
{
|
||
// 非靶病灶疗效为 ND
|
||
result = NoTargetAssessment.ND;
|
||
}
|
||
// else if (上次非靶病灶评估结果为非iUPD && (任一非靶病灶状态评估为“进一步增大（iCPD）||出现至少1个上一访视未评估为“显著增大（iUPD）”的病灶本次访视评估为“显著增大（iUPD）”))
|
||
else if (!data.LastNoTargetLesion.EqEnum(NoTargetAssessment.iUPD) && (data.ExistiCPD || data.LastNoUPD))
|
||
{
|
||
// 非靶病灶疗效为 iCPD
|
||
result = NoTargetAssessment.iCPD;
|
||
}
|
||
// else if (上次非靶病灶评估结果为非iCPD && 任一非靶病灶状态评估为“进一步增大（iCPD）”或“显著增大（iUPD）”)
|
||
else if (!data.LastNoTargetLesion.EqEnum(NoTargetAssessment.iCPD) && (data.ExistiCPD || data.ExistiUPD))
|
||
{
|
||
// 非靶病灶疗效为 iCPD
|
||
result = NoTargetAssessment.iCPD;
|
||
}
|
||
// else if (满足RECIST1.1的PD标准 && 任一非靶病灶状态评估为“显著增大（iUPD）”)
|
||
else if (data.RECISTPD && data.ExistiUPD)
|
||
{
|
||
// 非靶病灶疗效为 iUPD
|
||
result = NoTargetAssessment.iUPD;
|
||
}
|
||
// else if (有任一非靶病灶为NE状态)
|
||
else if (data.HaveNeLesion)
|
||
{
|
||
// 非靶病灶疗效为 NE
|
||
result = NoTargetAssessment.NE;
|
||
}
|
||
// else if (全部非靶病灶均为“消失”状态)
|
||
else if (data.AllVanish)
|
||
{
|
||
// 非靶病灶疗效为 iCR
|
||
result = NoTargetAssessment.iCR;
|
||
}
|
||
// else
|
||
else
|
||
{
|
||
// 非靶病灶疗效为 iNN
|
||
result = NoTargetAssessment.iNN;
|
||
}
|
||
|
||
return result.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region IRECIST新靶病灶评估
|
||
|
||
/// <summary>
|
||
/// 获取IRECIST新靶病灶评估
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// if（所有新靶病灶消失或一直不存在任何新靶病灶）
|
||
/// {
|
||
/// 疗效为 ND
|
||
/// }
|
||
/// else if (上一访视新靶病灶评估为“iUPD” && 满足iSOD增加5mm)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (上一访视新靶病灶评估为“iCPD”&& 有"存在"状态的新靶病灶)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (有存在状态的新靶病灶时评估为该结果)
|
||
/// {
|
||
/// 疗效为 iUPD
|
||
/// }
|
||
/// else if (至少有一个新靶病无法评估)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// </remarks>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNewTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return TargetAssessment.NA.GetEnumInt();
|
||
}
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
var newTargetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
|
||
var sodQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SOD).Select(x => x.QuestionId).FirstOrDefault();
|
||
IRECISTNewTargetLesionDto data = new IRECISTNewTargetLesionDto()
|
||
{
|
||
// 不存在新靶病灶
|
||
NotExistsNewTargetLesion = tableQuestion.Count() == 0,
|
||
|
||
// 所有状态为消失
|
||
AllVanish = true,
|
||
|
||
// 上一访视新靶病灶评估
|
||
LastTaskNewTargetLesion = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == newTargetLesionQuestionId)
|
||
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
|
||
|
||
//SOD增加5mm以上
|
||
ISODAdd5mm = await GetSODData(inDto) - (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == sodQuestionId)
|
||
.Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0() >= 5,
|
||
|
||
//有"存在"状态的新靶病灶
|
||
HaveExixtsState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Exist)),
|
||
|
||
// 至少有一个新靶病无法评估
|
||
ExixtsUnevaluableState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Exist)),
|
||
|
||
};
|
||
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
data.AllVanish = data.AllVanish && item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Loss));
|
||
}
|
||
|
||
NewTargetLesionAssessment result = NewTargetLesionAssessment.ND;
|
||
|
||
// if（所有新靶病灶消失或一直不存在任何新靶病灶）
|
||
if(data.NotExistsNewTargetLesion||data.AllVanish)
|
||
{
|
||
// 疗效为 ND
|
||
result = NewTargetLesionAssessment.ND;
|
||
}
|
||
// else if (上一访视新靶病灶评估为“iUPD” && 满足iSOD增加5mm)
|
||
else if(data.LastTaskNewTargetLesion.EqEnum(NewTargetLesionAssessment.iUPD)&&data.ISODAdd5mm)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewTargetLesionAssessment.iCPD;
|
||
}
|
||
// else if (上一访视新靶病灶评估为“iCPD”&& 有"存在"状态的新靶病灶)
|
||
else if (data.LastTaskNewTargetLesion.EqEnum(NewTargetLesionAssessment.iCPD) && data.HaveExixtsState)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewTargetLesionAssessment.iCPD;
|
||
}
|
||
// else if (有存在状态的新靶病灶时评估为该结果)
|
||
else if ( data.HaveExixtsState)
|
||
{
|
||
// 疗效为 iUPD
|
||
result = NewTargetLesionAssessment.iUPD;
|
||
}
|
||
// else if (至少有一个新靶病无法评估)
|
||
else if (data.ExixtsUnevaluableState)
|
||
{
|
||
// 疗效为 NE
|
||
result = NewTargetLesionAssessment.iUPD;
|
||
}
|
||
|
||
return result.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region 获取新非靶病灶评估
|
||
/// <summary>
|
||
/// 获取新非靶病灶评估
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// if（所有新非靶病灶消失或一直不存在任何新非靶病灶时评估为该结果）
|
||
/// {
|
||
/// 疗效为 ND
|
||
/// }
|
||
/// else if (上一访视新非靶病灶评估为“iUPD” && 满足任一新非靶病灶状态为“增大”)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (上一访视新非靶病灶评估为“iCPD”&& 有"存在"状态的新非靶病灶)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (当有存在状态的新非靶病灶)
|
||
/// {
|
||
/// 疗效为 iUPD
|
||
/// }
|
||
/// else if (至少有一个新非靶病无法评估)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// </remarks>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNewNoTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewNonTargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
var newTargetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
var newNoTargetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewNoTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
|
||
IRECISTNewNoTargetLesionDto data = new IRECISTNewNoTargetLesionDto()
|
||
{
|
||
// 不存在新非靶病灶
|
||
NotExistsNewNoTargetLesion = tableQuestion.Count() == 0,
|
||
|
||
// 所有状态为消失
|
||
AllVanish = tableQuestion.Count() == tableQuestion.Where(x => x.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Loss))).Count(),
|
||
|
||
// 上一访视新非靶病灶评估
|
||
LastTaskNewNoTargetLesion = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == newNoTargetLesionQuestionId)
|
||
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
|
||
|
||
//当前访视的新靶病灶评估
|
||
NewTargetLesion = inDto.QuestionInfo.Where(x=>x.QuestionId== newTargetLesionQuestionId).Select(x=>x.Answer).FirstIsNullReturnEmpty(),
|
||
|
||
// 任一新非靶病灶状态为“增大”
|
||
ExixtsEnlargementState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Progression)),
|
||
|
||
// 有"存在"状态的病灶
|
||
HaveExixtsState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Exist)),
|
||
|
||
// 至少有一个病灶无法评估
|
||
ExixtsUnevaluableState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.NotEvaluable)),
|
||
};
|
||
|
||
NewNoTargetLesionAssessment result = NewNoTargetLesionAssessment.ND;
|
||
|
||
// if（所有新非靶病灶消失或一直不存在任何新非靶病灶时评估为该结果）
|
||
if(data.NotExistsNewNoTargetLesion|| data.AllVanish)
|
||
{
|
||
// 疗效为 ND
|
||
result = NewNoTargetLesionAssessment.ND;
|
||
}
|
||
// else if (上一访视新非靶病灶评估为“iUPD” && 满足任一新非靶病灶状态为“增大”)
|
||
else if(data.LastTaskNewNoTargetLesion.EqEnum(NewNoTargetLesionAssessment.iUPD)&& data.ExixtsEnlargementState)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewNoTargetLesionAssessment.iCPD;
|
||
}
|
||
// else if (上一访视新非靶病灶评估为“iCPD”&& 有"存在"状态的新非靶病灶)
|
||
else if (data.LastTaskNewNoTargetLesion.EqEnum(NewNoTargetLesionAssessment.iCPD) && data.HaveExixtsState)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewNoTargetLesionAssessment.iCPD;
|
||
}
|
||
// else if (当有存在状态的新非靶病灶)
|
||
else if (data.HaveExixtsState)
|
||
{
|
||
// 疗效为 iUPD
|
||
result = NewNoTargetLesionAssessment.iUPD;
|
||
}
|
||
// else if (至少有一个新非靶病无法评估)
|
||
else if(data.ExixtsUnevaluableState)
|
||
{
|
||
// 疗效为 NE
|
||
result = NewNoTargetLesionAssessment.NE;
|
||
}
|
||
|
||
return result.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region 其它既往新病灶评估
|
||
/// <summary>
|
||
/// 获取其它既往新病灶评估
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// if（有其它既往新病灶消失或一直不存在任何其它既往新病灶）
|
||
/// {
|
||
/// 疗效为 ND
|
||
/// }
|
||
/// else if (任一病灶从非“存在”状态改为“存在”状态)
|
||
/// {
|
||
/// 疗效为 iUPD
|
||
/// }
|
||
/// else if (至少有一个其它既往新病灶无法评估)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// else if (至少有一个其它既往新病灶为疑似状态)
|
||
/// {
|
||
/// 疗效为 疑似
|
||
/// }
|
||
/// </remarks>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetOtherNewTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.OtherPreviousNewLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
|
||
|
||
// 找上一次任务 未被评为显著增大的非靶病灶
|
||
ReadingCalculateDto lastTaskCalculateDto = await _generalCalculateService.GetReadingCalculateDto(lastVisitTaskId);
|
||
|
||
var lastTaskNoExistIndexs = lastTaskCalculateDto.QuestionInfo.Where(x => x.LesionType == LesionType.OtherPreviousNewLesion).SelectMany(x => x.TableRowInfoList)
|
||
.Where(x => x.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && !x.Answer.EqEnum(OtherPreviousNewLesionState.Exists))).Select(x => x.RowIndex).ToList();
|
||
|
||
IRECISTOtherNewTargetLesionDto data = new IRECISTOtherNewTargetLesionDto()
|
||
{
|
||
// 不存在其他既往新病灶
|
||
NotExistsOtherNewTargetLesion = tableQuestion.Count() == 0,
|
||
|
||
// 所有状态为消失
|
||
AllVanish = tableQuestion.Count() == tableQuestion.Where(x => x.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Loss))).Count(),
|
||
|
||
// 当任一病灶从非“存在”状态改为“存在”状态
|
||
LastTaskNoExists = tableQuestion.Where(x => lastTaskNoExistIndexs.Contains(x.RowIndex)).SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Exists)),
|
||
|
||
// 至少有一个病灶无法评估
|
||
ExixtsUnevaluableState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.NotEvaluable)),
|
||
|
||
// 至少有一个其它既往新病灶为疑似状态
|
||
ExixtsSuspectedState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Equivocal)),
|
||
|
||
};
|
||
|
||
OtherPreviousNewLesionAssessment result = OtherPreviousNewLesionAssessment.ND;
|
||
|
||
// if（有其它既往新病灶消失或一直不存在任何其它既往新病灶）
|
||
if (data.NotExistsOtherNewTargetLesion || data.AllVanish)
|
||
{
|
||
// 疗效为 ND
|
||
result = OtherPreviousNewLesionAssessment.ND;
|
||
}
|
||
// else if (任一病灶从非“存在”状态改为“存在”状态)
|
||
else if (data.LastTaskNoExists)
|
||
{
|
||
// 疗效为 iUPD
|
||
result = OtherPreviousNewLesionAssessment.iUPD;
|
||
}
|
||
// else if (至少有一个其它既往新病灶无法评估)
|
||
else if (data.ExixtsUnevaluableState)
|
||
{
|
||
// 疗效为 NE
|
||
result = OtherPreviousNewLesionAssessment.NE;
|
||
}
|
||
// else if (至少有一个其它既往新病灶为疑似状态)
|
||
else if (data.ExixtsSuspectedState)
|
||
{
|
||
// 疗效为 疑似
|
||
result = OtherPreviousNewLesionAssessment.Equivocal;
|
||
}
|
||
|
||
return result.GetEnumInt();
|
||
|
||
}
|
||
#endregion
|
||
|
||
#region 触发iRECIST后新病灶评估
|
||
/// <summary>
|
||
///
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// if现至少1个“存在”状态的触发iRECIST后新病灶）
|
||
/// {
|
||
/// 疗效为 是
|
||
/// }
|
||
/// else if (只要有一个触发iRECIST后新病灶评估为NE)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// else if (只要有一个触发iRECIST后新病灶评估为疑似)
|
||
/// {
|
||
/// 疗效为 疑似
|
||
/// }
|
||
/// else
|
||
/// {
|
||
/// 疗效为 否
|
||
/// }
|
||
///
|
||
/// </remarks>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNewLesionAfterTriggeringiRECSITAssessment(ReadingCalculateDto inDto)
|
||
{
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TriggeringIRECSIT).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
NewLesionAfterTriggeringiRECSITAssessment result = NewLesionAfterTriggeringiRECSITAssessment.No;
|
||
|
||
// if现至少1个“存在”状态的触发iRECIST后新病灶）
|
||
if (tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Exist)))
|
||
{
|
||
// 疗效为 是
|
||
result = NewLesionAfterTriggeringiRECSITAssessment.Yes;
|
||
}
|
||
// else if (只要有一个触发iRECIST后新病灶评估为NE)
|
||
else if (tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.NotEvaluable)))
|
||
{
|
||
// 疗效为 NE
|
||
result = NewLesionAfterTriggeringiRECSITAssessment.NE;
|
||
}
|
||
// else if (只要有一个触发iRECIST后新病灶评估为疑似)
|
||
else if (tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Equivocal)))
|
||
{
|
||
// 疗效为 疑似
|
||
result = NewLesionAfterTriggeringiRECSITAssessment.Equivocal;
|
||
}
|
||
// else
|
||
else
|
||
{
|
||
// 疗效为 否
|
||
result = NewLesionAfterTriggeringiRECSITAssessment.No;
|
||
}
|
||
|
||
return result.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region 获取新病灶评估
|
||
|
||
|
||
/// <summary>
|
||
/// 获取新病灶评估
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// if(新靶病灶为ND&&新非靶病灶为ND&&其它既往新病灶为ND&&不存在触发iRECIST后新病灶）
|
||
/// {
|
||
/// 疗效为 ND
|
||
/// }
|
||
/// else if (新靶病灶为iCPD||新非靶病灶为iCPD)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (前一访视新病灶评估为iCPD && (新靶病灶有存在病灶 || 新非靶病灶有存在状态病灶 || 其它既往新病灶有存在的病灶 || 触发iRECIST后新病灶有存在病灶))
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (前一访视新病灶评估为iUPD && 新靶病灶上个访视评估为NE，本次访视评估为iUPD)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (前一访视新病灶评估为iUPD && 新非靶病灶上个访视评估为NE，本次访视评估为iUPD)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (前一访视新病灶评估为iUPD && 其它既往新病灶上个访视评估为NE或疑似，本次访视评估为iUPD)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (前一访视新病灶评估为iUPD && 触发iRECIST后新病灶评估上个访视评估为NE或否或疑似，本次访视评估为是)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (新靶病灶评估为iUPD || 新非靶病灶评估为iUPD || 其它既往新病灶评估为iUPD || 触发iRECIST后新病灶评估上个访视评估为是)
|
||
/// {
|
||
/// 疗效为 iUPD
|
||
/// }
|
||
/// else if (新靶病灶、新非靶病灶、其它既往新病灶任一项评估为NE)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// else if (其它既往新病灶或触发iRECIST后新病灶评估为“疑似”)
|
||
/// {
|
||
/// 疗效为 疑似
|
||
/// }
|
||
/// </remarks>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNewLesionAssessment(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
NewLesionAssessment? result = null;
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
ReadingCalculateDto lastTaskCalculateDto = await _generalCalculateService.GetReadingCalculateDto(lastVisitTaskId);
|
||
IRECISTNewLesionAssessmentDto data = new IRECISTNewLesionAssessmentDto()
|
||
{
|
||
//上一次任务的新病灶评估为iUPD
|
||
LastTaskNewLesioniUPD = lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.iCPD)),
|
||
};
|
||
|
||
// if(新靶病灶为ND&&新非靶病灶为ND&&其它既往新病灶为ND&&不存在触发iRECIST后新病灶）
|
||
if(inDto.QuestionInfo.Any(x=>x.QuestionType==QuestionType.NewTargetLesion&&x.Answer.EqEnum(NewTargetLesionAssessment.ND))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.ND))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.ND))
|
||
&& inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TriggeringIRECSIT).SelectMany(x => x.TableRowInfoList).Count()==0)
|
||
{
|
||
// 疗效为 ND
|
||
result = NewLesionAssessment.ND;
|
||
}
|
||
// else if (新靶病灶为iCPD||新非靶病灶为iCPD)
|
||
else if(inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.iCPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.iCPD)))
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewLesionAssessment.iCPD;
|
||
}
|
||
// else if (前一访视新病灶评估为iCPD && (新靶病灶有存在病灶 || 新非靶病灶有存在状态病灶 || 其它既往新病灶有存在的病灶 || 触发iRECIST后新病灶有存在病灶))
|
||
else if(data.LastTaskNewLesioniUPD&&
|
||
(inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).Count() > 0
|
||
|| inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewNonTargetLesion).SelectMany(x => x.TableRowInfoList).Count() > 0
|
||
|| inDto.QuestionInfo.Where(x => x.LesionType == LesionType.OtherPreviousNewLesion).SelectMany(x => x.TableRowInfoList).Count() > 0
|
||
|| inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TriggeringIRECSIT).SelectMany(x => x.TableRowInfoList).Count() > 0
|
||
)
|
||
)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewLesionAssessment.iCPD;
|
||
}
|
||
// else if (前一访视新病灶评估为iUPD && 新靶病灶上个访视评估为NE，本次访视评估为iUPD)
|
||
else if(data.LastTaskNewLesioniUPD &&
|
||
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.iUPD))
|
||
)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewLesionAssessment.iCPD;
|
||
}
|
||
// else if (前一访视新病灶评估为iUPD && 新非靶病灶上个访视评估为NE，本次访视评估为iUPD)
|
||
else if(data.LastTaskNewLesioniUPD
|
||
&& lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.NE))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.iUPD))
|
||
)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewLesionAssessment.iCPD;
|
||
}
|
||
// else if (前一访视新病灶评估为iUPD && 其它既往新病灶上个访视评估为NE或疑似，本次访视评估为iUPD)
|
||
else if (data.LastTaskNewLesioniUPD
|
||
&& lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && (x.Answer.EqEnum(OtherPreviousNewLesionAssessment.NE)|| x.Answer.EqEnum(OtherPreviousNewLesionAssessment.Equivocal)))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.iUPD))
|
||
)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewLesionAssessment.iCPD;
|
||
}
|
||
// else if (前一访视新病灶评估为iUPD && 触发iRECIST后新病灶评估上个访视评估为NE或否或疑似，本次访视评估为是)
|
||
else if(data.LastTaskNewLesioniUPD
|
||
&& lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && (x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.NE)|| x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.No) || x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Equivocal)))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Yes))
|
||
)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = NewLesionAssessment.iCPD;
|
||
}
|
||
// else if (新靶病灶评估为iUPD || 新非靶病灶评估为iUPD || 其它既往新病灶评估为iUPD || 触发iRECIST后新病灶评估上个访视评估为是)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.iUPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.iUPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.iUPD))
|
||
|| lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Yes))
|
||
)
|
||
{
|
||
// 疗效为 iUPD
|
||
result = NewLesionAssessment.iUPD;
|
||
}
|
||
// else if (新靶病灶、新非靶病灶、其它既往新病灶任一项评估为NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.NE))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.NE))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.NE))
|
||
)
|
||
{
|
||
// 疗效为 NE
|
||
result = NewLesionAssessment.NE;
|
||
}
|
||
// else if (其它既往新病灶或触发iRECIST后新病灶评估为“疑似”)
|
||
else if (
|
||
inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.Equivocal))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Equivocal))
|
||
)
|
||
{
|
||
// 疗效为 疑似
|
||
result = NewLesionAssessment.Suspected;
|
||
}
|
||
|
||
|
||
return result == null ? string.Empty : ((NewLesionAssessment)result).GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
|
||
#region 获取新病灶评估
|
||
/// <summary>
|
||
/// 获取新病灶评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNewLesionIRECSITEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
// 逻辑改了 现在转变后全部都是NA;
|
||
return NewLesionAssessment.NA.GetEnumInt();
|
||
|
||
NewLesionAssessment result = NewLesionAssessment.No;
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return NewLesionAssessment.NA.GetEnumInt();
|
||
}
|
||
|
||
var newTargetQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
|
||
|
||
var newNonTargetQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewNonTargetLesion).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
|
||
|
||
var OtherPreviousNewLesionQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.OtherPreviousNewLesion).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
|
||
|
||
var triggeringQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TriggeringIRECSIT).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
|
||
|
||
// 当前访视存在至少一个明确新病灶
|
||
if (newTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Exist))
|
||
|| newNonTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Exist))
|
||
|| OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Exists))
|
||
|| triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Exist))
|
||
|
||
)
|
||
{
|
||
result = NewLesionAssessment.Yes;
|
||
}
|
||
//只要有任何一个新病灶状态为“无法评估”
|
||
else if (newTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.NotEvaluable))
|
||
|| newNonTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.NotEvaluable))
|
||
|| OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.NotEvaluable))
|
||
|| triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.NotEvaluable))
|
||
|
||
)
|
||
{
|
||
result = NewLesionAssessment.NE;
|
||
}
|
||
//当前访视不存在明确新病灶且存在至少一个疑似新病灶
|
||
else if ( (!OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Exists)) && OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Equivocal)))
|
||
|| (!triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Exist)) && triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Equivocal)))
|
||
|
||
)
|
||
{
|
||
result = NewLesionAssessment.Suspected;
|
||
}
|
||
|
||
|
||
else
|
||
{
|
||
result = NewLesionAssessment.No;
|
||
}
|
||
return result.GetEnumInt();
|
||
|
||
}
|
||
#endregion
|
||
|
||
#region iRECSIT整体肿瘤评估
|
||
|
||
/// <summary>
|
||
///
|
||
/// </summary>
|
||
/// <remarks>
|
||
/// if（上一访视评估为iUPD或iCPD&&靶病灶评估、非靶病灶评估或新病灶评估任一项为iCPD）
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (上一访视评估为iUPD或iCPD&&靶病灶评估、非靶病灶评估或新病灶评估任一项从前一访视非iUPD结果评估为当前访视iUPD)
|
||
/// {
|
||
/// 疗效为 iCPD
|
||
/// }
|
||
/// else if (靶病灶评估为iUPD || 非靶病灶评估为iUPD || 新病灶评估为iUPD)
|
||
/// {
|
||
/// 疗效为 iUPD
|
||
/// }
|
||
/// else if ((靶病灶评估为iCR || 非靶病灶评估为iCR) && 新病灶评估为ND)
|
||
/// {
|
||
/// 疗效为 iCR
|
||
/// }
|
||
/// else if (靶病灶评估为iPR && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
|
||
/// {
|
||
/// 疗效为 iPR
|
||
/// }
|
||
/// else if (靶病灶评估为iPR && 非靶病灶评估为iNN或NE && 新病灶评估为否或疑似或NE)
|
||
/// {
|
||
/// 疗效为 iPR
|
||
/// }
|
||
/// else if (靶病灶评估为iPR && 非靶病灶评估为iCR或ND && 新病灶评估为疑似或NE)
|
||
/// {
|
||
/// 疗效为 iPR
|
||
/// }
|
||
/// else if (靶病灶评估为ND && 非靶病灶评估为iCR && 新病灶评估为疑似或NE)
|
||
/// {
|
||
/// 疗效为 iPR
|
||
/// }
|
||
/// else if (靶病灶评估为iSD && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
|
||
/// {
|
||
/// 疗效为 iSD
|
||
/// }
|
||
/// else if (靶病灶评估为ND && 非靶病灶评估为iNN && 新病灶评估为ND或疑似或NE)
|
||
/// {
|
||
/// 疗效为 iNN
|
||
/// }
|
||
/// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为ND或疑似)
|
||
/// {
|
||
/// 疗效为 ND
|
||
/// }
|
||
/// else if (靶病灶评估为NE && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// else if (靶病灶评估为ND && 非靶病灶评估为NE && 新病灶评估为否或疑似或NE)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为NE)
|
||
/// {
|
||
/// 疗效为 NE
|
||
/// }
|
||
/// </remarks>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetIRECSITTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
ReadingCalculateDto lastTaskCalculateDto = await _generalCalculateService.GetReadingCalculateDto(lastVisitTaskId);
|
||
OverallAssessment? result = null;
|
||
IRECISTTargetLesionEvaluateDto data = new IRECISTTargetLesionEvaluateDto()
|
||
{
|
||
LastTaskLesioniUPDOriCPD = lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.Tumor && (x.Answer.EqEnum(OverallAssessment.iCPD) || x.Answer.EqEnum(OverallAssessment.iUPD))),
|
||
};
|
||
|
||
// if（上一访视评估为iUPD或iCPD&&靶病灶评估、非靶病灶评估或新病灶评估任一项为iCPD）
|
||
if (data.LastTaskLesioniUPDOriCPD
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iCPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.iCPD))))
|
||
{
|
||
// 疗效为 iCPD
|
||
result = OverallAssessment.iCPD;
|
||
|
||
}
|
||
// else if (上一访视评估为iUPD或iCPD&&靶病灶评估、非靶病灶评估或新病灶评估任一项从前一访视非iUPD结果评估为当前访视iUPD)
|
||
if (data.LastTaskLesioniUPDOriCPD
|
||
&& (lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && !x.Answer.EqEnum(TargetAssessment.iUPD))
|
||
|| lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && !x.Answer.EqEnum(NoTargetAssessment.iUPD))
|
||
|| lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && !x.Answer.EqEnum(NewTargetLesionAssessment.iUPD)))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iUPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iUPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.iUPD)))
|
||
)
|
||
{
|
||
// 疗效为 iCPD
|
||
result = OverallAssessment.iCPD;
|
||
}
|
||
// else if (靶病灶评估为iUPD || 非靶病灶评估为iUPD || 新病灶评估为iUPD)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iUPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iUPD))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.iUPD)))
|
||
{
|
||
// 疗效为 iUPD
|
||
result = OverallAssessment.iUPD;
|
||
}
|
||
// else if ((靶病灶评估为iCR || 非靶病灶评估为iCR) && 新病灶评估为ND)
|
||
else if (
|
||
(inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iCR))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR)))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.ND))
|
||
)
|
||
{
|
||
// 疗效为 iCR
|
||
result = OverallAssessment.iCR;
|
||
}
|
||
// else if (靶病灶评估为iPR && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iPR))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
|
||
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.ND))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 iPR
|
||
result = OverallAssessment.iPR;
|
||
}
|
||
// else if (靶病灶评估为iPR && 非靶病灶评估为iNN或NE && 新病灶评估为否或疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iPR))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
|
||
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.No))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 iPR
|
||
result = OverallAssessment.iPR;
|
||
}
|
||
// else if (靶病灶评估为iPR && 非靶病灶评估为iCR或ND && 新病灶评估为疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iPR))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
|
||
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 iPR
|
||
result = OverallAssessment.iPR;
|
||
}
|
||
// else if (靶病灶评估为ND && 非靶病灶评估为iCR && 新病灶评估为疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|
||
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 iPR
|
||
result = OverallAssessment.iPR;
|
||
}
|
||
// else if (靶病灶评估为iSD && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iSD))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
|
||
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 iSD
|
||
result = OverallAssessment.iSD;
|
||
}
|
||
// else if (靶病灶评估为ND && 非靶病灶评估为iNN && 新病灶评估为ND或疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.ND))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 iNN
|
||
result = OverallAssessment.iNN;
|
||
}
|
||
// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为ND或疑似)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.ND))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
))
|
||
{
|
||
// 疗效为 ND
|
||
result = OverallAssessment.ND;
|
||
}
|
||
// else if (靶病灶评估为NE && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.NE))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
|
||
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.ND))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 NE
|
||
result = OverallAssessment.NE;
|
||
}
|
||
// else if (靶病灶评估为ND && 非靶病灶评估为NE && 新病灶评估为否或疑似或NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
|
||
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|
||
|
||
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.No))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|
||
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
))
|
||
{
|
||
// 疗效为 NE
|
||
result = OverallAssessment.NE;
|
||
}
|
||
// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为NE)
|
||
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
|
||
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewLesionAssessment.NE))
|
||
|
||
)
|
||
{
|
||
// 疗效为 NE
|
||
result = OverallAssessment.NE;
|
||
}
|
||
|
||
return result == null ? string.Empty : ((OverallAssessment)result).GetEnumInt();
|
||
}
|
||
#endregion
|
||
#endregion
|
||
|
||
#region 转化时计算
|
||
|
||
#region 获取转化的靶病灶评估
|
||
/// <summary>
|
||
/// 获取转化的靶病灶评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetConvertingTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
var beforeConvertedAnswer = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.BeforeConvertedTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.TargetLesion).Select(x => x.Answer).FirstOrDefaultAsync();
|
||
|
||
Dictionary<string, string> answerConverDic = new Dictionary<string, string>()
|
||
{
|
||
{TargetAssessment.SD.GetEnumInt(),TargetAssessment.iSD.GetEnumInt() },
|
||
{TargetAssessment.PR.GetEnumInt(),TargetAssessment.iPR.GetEnumInt() },
|
||
{TargetAssessment.PD.GetEnumInt(),TargetAssessment.iUPD.GetEnumInt() },
|
||
{TargetAssessment.CR.GetEnumInt(), TargetAssessment.iCR.GetEnumInt() },
|
||
};
|
||
|
||
try
|
||
{
|
||
return answerConverDic[beforeConvertedAnswer];
|
||
|
||
}
|
||
catch (Exception)
|
||
{
|
||
|
||
return beforeConvertedAnswer;
|
||
|
||
}
|
||
|
||
}
|
||
#endregion
|
||
|
||
|
||
|
||
#region 获取转化的非靶病灶评估
|
||
|
||
/// <summary>
|
||
/// 获取转化的非靶病灶评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetConvertingNoTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
var beforeConvertedAnswer = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.BeforeConvertedTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.NoTargetLesion).Select(x => x.Answer).FirstOrDefaultAsync();
|
||
|
||
Dictionary<string, string> answerConverDic = new Dictionary<string, string>()
|
||
{
|
||
{NoTargetAssessment.NN.GetEnumInt(),NoTargetAssessment.iNN.GetEnumInt() },
|
||
{NoTargetAssessment.PD.GetEnumInt(),NoTargetAssessment.iUPD.GetEnumInt() },
|
||
{NoTargetAssessment.CR.GetEnumInt(), NoTargetAssessment.iCR.GetEnumInt() },
|
||
};
|
||
|
||
try
|
||
{
|
||
return answerConverDic[beforeConvertedAnswer];
|
||
|
||
}
|
||
catch (Exception)
|
||
{
|
||
|
||
return beforeConvertedAnswer;
|
||
|
||
}
|
||
}
|
||
#endregion
|
||
|
||
#region 获取转化的整体肿瘤评估
|
||
|
||
/// <summary>
|
||
/// 获取转化的整体肿瘤评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetConvertingTumor(ReadingCalculateDto inDto)
|
||
{
|
||
var beforeConvertedAnswer = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.BeforeConvertedTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.Tumor).Select(x => x.Answer).FirstOrDefaultAsync();
|
||
|
||
Dictionary<string, string> answerConverDic = new Dictionary<string, string>()
|
||
{
|
||
{OverallAssessment.NN.GetEnumInt(),OverallAssessment.iNN.GetEnumInt() },
|
||
{OverallAssessment.PD.GetEnumInt(),OverallAssessment.iUPD.GetEnumInt() },
|
||
{OverallAssessment.CR.GetEnumInt(), OverallAssessment.iCR.GetEnumInt() },
|
||
{OverallAssessment.SD.GetEnumInt(), OverallAssessment.iSD.GetEnumInt() },
|
||
{OverallAssessment.PR.GetEnumInt(), OverallAssessment.iPR.GetEnumInt() },
|
||
};
|
||
|
||
try
|
||
{
|
||
return answerConverDic[beforeConvertedAnswer];
|
||
|
||
}
|
||
catch (Exception)
|
||
{
|
||
|
||
return beforeConvertedAnswer;
|
||
|
||
}
|
||
}
|
||
#endregion
|
||
#endregion
|
||
|
||
|
||
|
||
#region 获取靶病灶评估
|
||
/// <summary>
|
||
/// 获取靶病灶评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <remarks>
|
||
/// 靶病灶疗效评估算法-20230306确认版本：
|
||
///if（基线没有靶病灶）
|
||
///{
|
||
/// 靶病灶疗效为 ND
|
||
///}else
|
||
///{
|
||
/// 初始化靶病灶疗效为 SD
|
||
///
|
||
/// if (与基线期SOD相比减小≥30 %）
|
||
/// {
|
||
/// 靶病灶疗效为 PR
|
||
///
|
||
/// }
|
||
///
|
||
///if (非淋巴结靶病灶长径之和 == 0 并且所有淋巴结靶病灶的短径 < 10且淋巴结非靶病灶全部消失)
|
||
/// {
|
||
/// 靶病灶疗效为 CR
|
||
///
|
||
/// }
|
||
///
|
||
///if （有被评估为NE的单个靶病灶）
|
||
/// {
|
||
/// 靶病灶疗效为 NE
|
||
///
|
||
/// }
|
||
///
|
||
///if (最低点SOD > 0)
|
||
///{
|
||
/// if（比整体访视期间最低点SOD增加≥20 % 且与整个访视期间最低点相比增加的值≥5 mm）
|
||
/// {
|
||
/// 靶病灶疗效为 PD
|
||
///
|
||
/// }
|
||
///}
|
||
///else
|
||
///{
|
||
/// //进入该分支最低点SOD=0
|
||
/// if (当前访视SOD > 0 且与整个访视期间最低点相比增加的值≥5 mm)
|
||
/// {
|
||
/// 靶病灶疗效为PD
|
||
///
|
||
/// }
|
||
///}
|
||
///
|
||
///if（上次访视点评估是CR）
|
||
/// {
|
||
/// if (当前访视点淋巴结病灶,至少一个淋巴结靶病灶短径≥10 mm 并且该淋巴结靶病灶短径绝对增加值≥5 mm)
|
||
/// {
|
||
/// 靶病灶疗效为 PD
|
||
///
|
||
/// }
|
||
/// if (当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径＞0 mm。)
|
||
/// {
|
||
/// 靶病灶疗效为 PD
|
||
///
|
||
/// }
|
||
///}
|
||
///}
|
||
/// </remarks>
|
||
/// <returns></returns>
|
||
public async Task<string> GetTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return TargetAssessment.NA.GetEnumInt();
|
||
}
|
||
|
||
TargetLesionCalculateDto resultData = new TargetLesionCalculateDto()
|
||
{
|
||
|
||
|
||
// 是否存在靶病灶
|
||
ExistsTargetLesion = tableQuestion.Count() > 0,
|
||
|
||
// 最低SOD
|
||
LowSod = (await GetLowSODVisit(inDto)).Select(x => x.SOD).FirstOrDefault(),
|
||
|
||
// 当前Sod
|
||
PresentSod = (await GetSODData(inDto)) ?? 0,
|
||
|
||
//非淋巴结靶病灶长径之和 decimal
|
||
SumOfDiameter = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SumOfDiameter).Sum(x => x.Answer.IsNullOrEmptyReturn0()),
|
||
|
||
//所有淋巴结靶病灶的短径小于10mm bool
|
||
DiameterLessThan10 = true,
|
||
|
||
// SOD变化百分比
|
||
SODPercent = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()),
|
||
|
||
// SOD 百分比与基线期SOD相比减小≥30% bool
|
||
SODPercentBigger30 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) <= -30,
|
||
|
||
// SOD 百分比 与基线期SOD相比减小＜30% bool
|
||
SODPercentLess30 = 0 > inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) &&
|
||
|
||
inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) > -30,
|
||
|
||
// SOD 百分比 整体访视期间SOD最低点SOD相比增加＜20%
|
||
LowSODPercentLess20 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) < 20,
|
||
|
||
// SOD 百分比 比整体访视期间SOD最低点SOD增加≥20%
|
||
LowSODPercentBigger20 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 20,
|
||
|
||
// SOD 变化值 比整体访视期间SOD最低点SOD绝对增加值＜5 mm
|
||
LowSODChangeLess5 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowestIncrease).Sum(x => x.Answer.IsNullOrEmptyReturn0()) < 5,
|
||
|
||
// 比整体访视期间SOD最低点SOD绝对增加值≥5 mm
|
||
LowSODChangeBigger5 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowestIncrease).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 5,
|
||
|
||
// 被评估为NE的单个靶病灶 是否存在状态为不可评估的靶病灶
|
||
ExixtsNETargetLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.UnableEvaluate)),
|
||
|
||
//// 上次访视点整体肿瘤评估
|
||
LastTargetLesionEvaluate = string.Empty,
|
||
|
||
// 当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径＞0 mm
|
||
CurrentMajoreBigger0 = false,
|
||
|
||
// 当前访视点淋巴结病灶, 至少一个淋巴结靶病灶短径≥10 mm
|
||
CurrenShortBigger10 = false,
|
||
|
||
// 靶病灶短径增加值有5mm的Index
|
||
AddFiveIndexs = await GetIsAddFiveRowIndexs(inDto),
|
||
|
||
// 短径有10mm的Index
|
||
ShortBigger10Indexs = new List<decimal>(),
|
||
|
||
//淋巴结非靶病灶状态全部为消失
|
||
NonTargetStateIsLoss = true,
|
||
|
||
// 该淋巴结靶病灶短径绝对增加值≥5 mm
|
||
IsAddFive = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.IsAddFive && x.Answer.EqEnum(YesOrNoOrNa.Yes)).Count() > 0,
|
||
};
|
||
|
||
var nonTargetTableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
foreach (var item in nonTargetTableQuestion)
|
||
{
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
|
||
{
|
||
// 淋巴结非靶病灶状态全部为消失
|
||
resultData.NonTargetStateIsLoss = resultData.NonTargetStateIsLoss&& item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.State).Select(x => x.Answer).FirstOrDefault()== NoTargetState.Loss.GetEnumInt();
|
||
}
|
||
}
|
||
|
||
|
||
foreach (var item in tableQuestion)
|
||
{
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
|
||
{
|
||
// 淋巴结的短径
|
||
resultData.DiameterLessThan10 = resultData.DiameterLessThan10&&(item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() < 10;
|
||
|
||
var shortIsBigger10 = (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() >= 10;
|
||
resultData.CurrenShortBigger10= resultData.CurrenShortBigger10|| shortIsBigger10;
|
||
|
||
if (shortIsBigger10)
|
||
{
|
||
resultData.ShortBigger10Indexs.Add(item.RowIndex);
|
||
}
|
||
|
||
|
||
}
|
||
|
||
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && !x.Answer.EqEnum(YesOrNoOrNa.Yes)))
|
||
{
|
||
// 当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径
|
||
resultData.CurrentMajoreBigger0 = resultData.CurrentMajoreBigger0|| (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() > 0;
|
||
}
|
||
}
|
||
|
||
|
||
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
|
||
var questionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.Tumor).Select(x => x.QuestionId).FirstOrDefault();
|
||
resultData.LastTargetLesionEvaluate = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == questionId)
|
||
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty;
|
||
|
||
TargetAssessment result = TargetAssessment.SD;
|
||
//if（基线没有靶病灶）
|
||
if (!resultData.ExistsTargetLesion)
|
||
{
|
||
// 靶病灶疗效为 ND
|
||
result = TargetAssessment.ND;
|
||
}
|
||
else
|
||
{
|
||
//初始化靶病灶疗效为 SD
|
||
result = TargetAssessment.SD;
|
||
|
||
//if (与基线期SOD相比减小≥30 %）
|
||
if (resultData.SODPercentBigger30)
|
||
{
|
||
//靶病灶疗效为 PR
|
||
result = TargetAssessment.PR;
|
||
}
|
||
//if (非淋巴结靶病灶长径之和 == 0 并且所有淋巴结靶病灶的短径 < 10且淋巴结非靶病灶全部消失)
|
||
if (resultData.SumOfDiameter == 0 && resultData.DiameterLessThan10 && resultData.NonTargetStateIsLoss)
|
||
{
|
||
//靶病灶疗效为 CR
|
||
result = TargetAssessment.CR;
|
||
}
|
||
// if （有被评估为NE的单个靶病灶）
|
||
if (resultData.ExixtsNETargetLesion)
|
||
{
|
||
// 靶病灶疗效为 NE
|
||
result = TargetAssessment.NE;
|
||
}
|
||
//if (最低点SOD > 0)
|
||
if (resultData.LowSod > 0)
|
||
{
|
||
// if（比整体访视期间最低点SOD增加≥20 % 且与整个访视期间最低点相比增加的值≥5 mm）
|
||
if (resultData.LowSODPercentBigger20 && resultData.LowSODChangeBigger5)
|
||
{
|
||
// 靶病灶疗效为 PD
|
||
result = TargetAssessment.PD;
|
||
}
|
||
}
|
||
else
|
||
{
|
||
//进入该分支最低点SOD=0
|
||
// if (当前访视SOD > 0 且与整个访视期间最低点相比增加的值≥5 mm)
|
||
if (resultData.PresentSod > 0 && resultData.LowSODChangeBigger5)
|
||
{
|
||
// 靶病灶疗效为PD
|
||
result = TargetAssessment.PD;
|
||
}
|
||
}
|
||
//if（上次访视点评估是CR）
|
||
if (resultData.LastTargetLesionEvaluate.EqEnum(OverallAssessment.CR))
|
||
{
|
||
//if (当前访视点淋巴结病灶,至少一个淋巴结靶病灶短径≥10 mm 并且该淋巴结靶病灶短径绝对增加值≥5 mm)
|
||
// 换句话说 就是 短径≥10 的病灶 和 短径增加值≥5的病灶 的交集数量大于0
|
||
if (resultData.ShortBigger10Indexs.Intersect(resultData.AddFiveIndexs).ToList().Count()>0)
|
||
{
|
||
//靶病灶疗效为 PD
|
||
result = TargetAssessment.PD;
|
||
}
|
||
//if (当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径＞0 mm。)
|
||
if (resultData.CurrentMajoreBigger0)
|
||
{
|
||
//靶病灶疗效为 PD
|
||
result = TargetAssessment.PD;
|
||
}
|
||
}
|
||
|
||
|
||
|
||
#region 之前的逻辑 备注
|
||
//if (resultData.LastTargetLesionEvaluate.EqEnum(TargetAssessment.CR))
|
||
//{
|
||
// if (resultData.ExixtsNETargetLesion)
|
||
// {
|
||
// result = TargetAssessment.NE;
|
||
// }
|
||
// if (resultData.CurrenShortBigger10 && resultData.IsAddFive)
|
||
// {
|
||
// result = TargetAssessment.PD;
|
||
// }
|
||
// if (resultData.CurrentMajoreBigger0)
|
||
// {
|
||
// result = TargetAssessment.PD;
|
||
// }
|
||
//}
|
||
|
||
//else
|
||
//{
|
||
// if (resultData.LowSod != 0 && resultData.LowPercentBigger20 && resultData.LowChangeBigger5)
|
||
// {
|
||
// result = TargetAssessment.PD;
|
||
// }
|
||
// else
|
||
// {
|
||
// if (resultData.ExixtsNETargetLesion)
|
||
// {
|
||
// result = TargetAssessment.NE;
|
||
// }
|
||
// else
|
||
// {
|
||
// if (resultData.SODPercentBigger30)
|
||
// {
|
||
// if (resultData.LowPercentLess20 || resultData.LowChangeLess5)
|
||
// {
|
||
// result = TargetAssessment.PR;
|
||
// }
|
||
|
||
// if (resultData.SumOfDiameter == 0 && resultData.DiameterLessThan10 && resultData.NonTargetStateIsLoss)
|
||
// {
|
||
// result = TargetAssessment.CR;
|
||
// }
|
||
// }
|
||
// }
|
||
// }
|
||
|
||
|
||
//}
|
||
#endregion
|
||
|
||
|
||
}
|
||
|
||
return result.GetEnumInt();
|
||
}
|
||
#endregion
|
||
|
||
#region 获取非靶病灶评估
|
||
|
||
/// <summary>
|
||
/// 获取非靶病灶评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNoTargetLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
NoTargetAssessment result = NoTargetAssessment.NN;
|
||
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return NoTargetAssessment.NA.GetEnumInt();
|
||
}
|
||
|
||
var tableRows = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
var tableQuestions = tableRows.SelectMany(x => x.TableQuestionList).ToList();
|
||
|
||
//任意单个病灶 / 病灶组评估为“显著增大”
|
||
if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Increase)))
|
||
{
|
||
result = NoTargetAssessment.PD;
|
||
}
|
||
// 任意单个病灶/病灶组评估为“无法评估”并且没有“显著增大”
|
||
else if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.UnableEvaluate)) &&
|
||
!tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Increase))
|
||
)
|
||
{
|
||
result = NoTargetAssessment.NE;
|
||
}
|
||
// 所有单个病灶/病灶组评估为”存在”或者有些评估为“消失”有些评估为“存在”,且没有“显著增大”和“无法评估”的病灶
|
||
else if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Exist))
|
||
&& !tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && (x.Answer.EqEnum(NoTargetState.Increase) || x.Answer.EqEnum(NoTargetState.UnableEvaluate)))
|
||
|
||
)
|
||
{
|
||
result = NoTargetAssessment.NN;
|
||
}
|
||
//所有单个病灶/病灶组状态评估状态为“消失”
|
||
else if (tableQuestions.Count(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Loss))== tableQuestions.Count(x=> x.QuestionMark == QuestionMark.State) && tableQuestions.Count(x => x.QuestionMark == QuestionMark.State)>0)
|
||
{
|
||
result = NoTargetAssessment.CR;
|
||
}
|
||
|
||
// 基线时没有非靶病灶
|
||
else if (tableQuestions.Count() == 0)
|
||
{
|
||
result = NoTargetAssessment.ND;
|
||
}
|
||
else
|
||
{
|
||
return string.Empty;
|
||
}
|
||
|
||
return result.GetEnumInt();
|
||
|
||
}
|
||
|
||
#endregion
|
||
|
||
#region 获取新病灶评估
|
||
/// <summary>
|
||
/// 获取新病灶评估
|
||
/// </summary>
|
||
/// <param name="inDto"></param>
|
||
/// <returns></returns>
|
||
public async Task<string> GetNewLesionEvaluate(ReadingCalculateDto inDto)
|
||
{
|
||
|
||
NewLesionAssessment result = NewLesionAssessment.No;
|
||
if (inDto.IsBaseLine)
|
||
{
|
||
return NewLesionAssessment.NA.GetEnumInt();
|
||
}
|
||
|
||
var tableRows = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewLesions).SelectMany(x => x.TableRowInfoList).ToList();
|
||
|
||
var tableQuestions = tableRows.SelectMany(x => x.TableQuestionList).ToList();
|
||
|
||
|
||
|
||
// 当前访视存在至少一个明确新病灶
|
||
if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.Exist)))
|
||
{
|
||
result = NewLesionAssessment.Yes;
|
||
}
|
||
//只要有任何一个新病灶状态为“无法评估”
|
||
else if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.UnableEvaluate)))
|
||
{
|
||
result = NewLesionAssessment.NE;
|
||
}
|
||
//当前访视不存在明确新病灶且存在至少一个疑似新病灶
|
||
else if (!tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.Exist)) &&
|
||
tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.Suspected))
|
||
)
|
||
{
|
||
result = NewLesionAssessment.Suspected;
|
||
}
|
||
|
||
|
||
else
|
||
{
|
||
result = NewLesionAssessment.No;
|
||
}
|
||
return result.GetEnumInt();
|
||
|
||
}
|
||
#endregion
|
||
|
||
#endregion
|
||
|
||
}
|
||
|
||
}
|