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更新Lugano 2014标准

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helongjun 2024-03-08 11:30:16 +08:00
parent 35cea41d72
commit f993a5e13c
27 changed files with 0 additions and 661 deletions

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Lugano/20231205 lugano病灶验证.xlsx
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Lugano/20231205-Lugano 2014_ECRF.xlsx
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Lugano/20231205-Lugano 2014默认部位列表-确认版.xlsx
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Lugano/20231205-Lugano2014 标准版阅片单元配置表格问题.xlsx
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Lugano/20231205-lugano阅片标准优化需求.docx
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Lugano/20231205-lugano阅片标准需求.docx
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Lugano/评估算法/1、靶病灶评估.cs
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"默认SD"
if(当前访视是基线)
{
"NA";
}
else if(基线未选择靶病灶)
{
"ND";
}
else if(任一单个病灶进展即可)
{
"PD";
}
else if(当前访视存在至少一个状态为“不可评估”的靶病灶)
{
"NE";
}
else if(当前访视非淋巴结靶病灶全部消失 && （当前访视淋巴结靶病灶的状态全部变为“消失” 或者 "太小" ）)
{
"CR";
}
else if(与基线相比SPD变化的百分比 <=- 50% )
{
"PR";
}

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Lugano/评估算法/2、非靶病灶评估.cs
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if(当前访视是基线)
{
"NA";
}
else if(基线未选择非靶病灶)
{
"ND";
}
else if(随访至少存在一个状态为“显著增大”的非靶病灶)
{
"PD";
}
else if( 随访存在至少一个状态为“不可评估”的非靶病灶)
{
"NE";
}
else if(所有单个病灶/病灶组状态评估状态为“消失”) //当前访视非靶病灶状态为消失的数量==非靶病灶的数量
{
"CR";
}
else
{
"PR/SD";
}

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Lugano/评估算法/3、新病灶评估.cs
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if(当前访视是基线)
{
"NA";
}
else if(当前访视存在至少一个明确新病灶)
{
"是";
}
else if(只要有任何一个新病灶状态为“无法评估”)
{
"无法评估";
}
else if(当前访视不存在明确新病灶且存在至少一个疑似新病灶)
{
"疑似";
}
else
{
"否";
}

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Lugano/评估算法/4、脾脏评估.cs
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return "脾脏状态";

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Lugano/评估算法/5、肝脏评估.cs
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return "肝脏状态";

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Lugano/评估算法/6、CMRI总体评估实现代码.cs
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public async Task<string> CTMRIEvaluation(ReadingCalculateDto inDto)
{
if (inDto.IsBaseLine)
{
return CTMRIOverallAssessment.NA.GetEnumInt();
}
// 靶病灶评估
var targetEvaluation = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.TargetLesion).Select(x => x.Answer).FirstOrDefault();
// 非靶病灶评估
var noTargetEvaluation = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NoTargetLesion).Select(x => x.Answer).FirstOrDefault();
// 存在新病灶
var existsNewTarget = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewLesionEvaluation).Select(x => x.Answer).FirstOrDefault();
// 肝脏评估
var liverEvaluation = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LiverAssessment).Select(x => x.Answer).FirstOrDefault();
// 脾脏评估
var spleenEvaluation = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SplenicEvaluation).Select(x => x.Answer).FirstOrDefault();
List<CalculationDto> data = new List<CalculationDto>() {
//ND ND 否/疑似 正常 正常 ND
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.ND }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.No, NewLesionAssessment.Suspected }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Normal }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.ND }),
},
//PD 任一结果 任一结果 任一结果 任一结果 PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.PD }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PD }),
},
//任一结果 PD 任一结果 任一结果 任一结果 PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.PD }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() {}),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PD }),
},
//任一结果 任一结果 是 任一结果 任一结果 PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.Yes }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PD }),
},
//任一结果 任一结果 任一结果 显著增大 任一结果 PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Increase }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PD }),
},
//任一结果 任一结果 任一结果 任一结果 显著增大 PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() {}),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Increase }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PD }),
},
//CR CR/ND 否 正常 正常 CR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.CR }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.CR, NoTargetAssessment.ND }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.No }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Normal }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.CR }),
},
//ND CR 否 正常 正常 CR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.CR }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.No }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Normal }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.CR }),
},
//NE 非PD 否/疑似/无法评估 非显著增大 非显著增大 NE
new CalculationDto(){
NotEq=new List<int>(){ 2,4,5},
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.NE }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.PD }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.No,NewLesionAssessment.Suspected, NewLesionAssessment.NE}),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Increase }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Increase }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.NE }),
},
//ND NE 否/疑似/无法评估（不为是） 正常/稳定/无法评估/部分缓解（非显著增大） 正常/稳定/无法评估/部分缓解（非显著增大） NE
new CalculationDto(){
NotEq=new List<int>(){ 3,4,5},
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.Yes }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Increase }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Increase }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.NE }),
},
//ND ND 无法评估 正常/稳定/无法评估/部分缓解（非显著增大） 正常/稳定/无法评估/部分缓解（非显著增大） NE
new CalculationDto(){
NotEq=new List<int>(){ 4,5},
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.ND }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.NE }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Increase }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Increase }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.NE }),
},
//ND ND 否/疑似 无法评估 正常/稳定/无法评估/部分缓解（非显著增大） NE
new CalculationDto(){
NotEq=new List<int>(){ 5},
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.ND }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.No,NewLesionAssessment.Suspected }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.NotEvaluable }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Increase }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.NE }),
},
// ND ND 否/疑似 正常/稳定 NE NE
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.ND }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.No,NewLesionAssessment.Suspected }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal,LiverAssessment.Stabilization }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.NotEvaluable }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.NE }),
},
//PR 非PD 否/疑似/无法评估（不为是） 正常/稳定 正常/部分缓解 PR
new CalculationDto(){
NotEq=new List<int>(){ 2,3},
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.PR }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.PD }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.Yes }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal,LiverAssessment.Stabilization}),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Normal,SpleenAssessment.Remission }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PR }),
},
//CR （PR/SD）或者NE 否/疑似/无法评估（不为是） 正常/部分缓解 正常/部分缓解 PR
new CalculationDto(){
NotEq=new List<int>(){ 3},
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.CR }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.PRSD,NoTargetAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.Yes,NewLesionAssessment.Yes }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal,LiverAssessment.Stabilization}),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Normal,SpleenAssessment.Remission }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PR }),
},
//CR CR/ND 疑似/无法评估 正常/稳定 正常/部分缓解 PR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.CR }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.CR,NoTargetAssessment.ND }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.Suspected, NewLesionAssessment.NE }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal,LiverAssessment.Stabilization}),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Normal,SpleenAssessment.Remission }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PR }),
},
// ND CR 疑似/无法评估 正常/稳定 正常/部分缓解 PR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { TargetAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { NoTargetAssessment.CR }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { NewLesionAssessment.Suspected, NewLesionAssessment.NE }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { LiverAssessment.Normal,LiverAssessment.Stabilization}),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { SpleenAssessment.Normal,SpleenAssessment.Remission }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PR }),
},
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<TargetAssessment>() { }),
Column2=ReadingCommon.EnumToString(new List<NoTargetAssessment>() { }),
Column3=ReadingCommon.EnumToString(new List<NewLesionAssessment>() { }),
Column4=ReadingCommon.EnumToString(new List<LiverAssessment>() { }),
Column5=ReadingCommon.EnumToString(new List<SpleenAssessment>() { }),
Column6=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.SD }),
},
};
var index= data.FindIndex(x =>
(x.NotEq.Contains(1) ? !x.Column1.Contains(targetEvaluation) : x.Column1.Contains(targetEvaluation) || x.Column1.Count() == 0) &&
(x.NotEq.Contains(2) ? !x.Column2.Contains(noTargetEvaluation) : x.Column2.Contains(noTargetEvaluation) || x.Column2.Count() == 0) &&
(x.NotEq.Contains(3) ? !x.Column3.Contains(existsNewTarget) : x.Column3.Contains(existsNewTarget) || x.Column3.Count() == 0) &&
(x.NotEq.Contains(4) ? !x.Column4.Contains(liverEvaluation) : x.Column4.Contains(liverEvaluation) || x.Column4.Count() == 0) &&
(x.NotEq.Contains(5) ? !x.Column5.Contains(spleenEvaluation) : x.Column5.Contains(spleenEvaluation) || x.Column5.Count() == 0))
;
Console.WriteLine(index);
var result = data.Where(x =>
(x.NotEq.Contains(1) ? !x.Column1.Contains(targetEvaluation) : x.Column1.Contains(targetEvaluation) || x.Column1.Count() == 0) &&
(x.NotEq.Contains(2) ? !x.Column2.Contains(noTargetEvaluation) : x.Column2.Contains(noTargetEvaluation) || x.Column2.Count() == 0) &&
(x.NotEq.Contains(3) ? !x.Column3.Contains(existsNewTarget) : x.Column3.Contains(existsNewTarget) || x.Column3.Count() == 0) &&
(x.NotEq.Contains(4) ? !x.Column4.Contains(liverEvaluation) : x.Column4.Contains(liverEvaluation) || x.Column4.Count() == 0) &&
(x.NotEq.Contains(5) ? !x.Column5.Contains(spleenEvaluation) : x.Column5.Contains(spleenEvaluation) || x.Column5.Count() == 0))
.Select(x => x.Column6.FirstOrDefault())
.FirstOrDefault();
return result??string.Empty;
}

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Lugano/评估算法/6、CTMRI总体评估-对应表.png
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Lugano/评估算法/7、FDG-PET评估-对应表.png
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Lugano/评估算法/7、FDG-PET评估实现代码.cs
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public async Task<string> GetFDGPETOverallAssessment(ReadingCalculateDto inDto)
{
if (inDto.IsBaseLine)
{
return FDGPETOverallAssessment.NA.GetEnumInt();
}
var existPET =await GetExistPET(inDto);
if (existPET.EqEnum(ReadingYesOrNo.No))
{
return FDGPETOverallAssessment.NE.GetEnumInt();
}
//FDGPETOverallAssessment result = FDGPETOverallAssessment.NA;
// PET5PS
var PET5PS = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.PET5PS).Select(x => x.Answer).FirstOrDefault();
// UptakeChange
var UptakeChange = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.UptakeChange).Select(x => x.Answer).FirstOrDefault();
// EvidenceFocalFDG
var EvidenceFocalFDG = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.EvidenceFocalFDG).Select(x => x.Answer).FirstOrDefault();
List<CalculationDto> data = new List<CalculationDto>() {
//NE NE NE NE
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<PET5PSScore>() { PET5PSScore.NE }),
Column2=ReadingCommon.EnumToString(new List<SUVChangeVSBaseline>() { SUVChangeVSBaseline.NotEvaluable }),
Column3=ReadingCommon.EnumToString(new List<FDGAffinityFociInBM>() { FDGAffinityFociInBM.NE}),
Column4=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
},
//NE/5分/4分/3分/2分/1分/X NE/增大/减少/无明显变化 是，存在新的/复发的FDG高亲和性病灶 PMD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<PET5PSScore>() { PET5PSScore.NE,PET5PSScore.Five,PET5PSScore.Four,PET5PSScore.Three,PET5PSScore.Two,PET5PSScore.One,PET5PSScore.X, }),
Column2=ReadingCommon.EnumToString(new List<SUVChangeVSBaseline>() { SUVChangeVSBaseline.NotEvaluable,SUVChangeVSBaseline.Increase,SUVChangeVSBaseline.Decrease,SUVChangeVSBaseline.DidNotChange, }),
Column3=ReadingCommon.EnumToString(new List<FDGAffinityFociInBM>() { FDGAffinityFociInBM.YesHaveNew,}),
Column4=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMD }),
},
//5分/4分 增大 NE/（是，存在新的/复发的FDG高亲和性病灶）/（是，存在持续的局灶性变化）/否 PMD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<PET5PSScore>() { PET5PSScore.Five,PET5PSScore.Four, }),
Column2=ReadingCommon.EnumToString(new List<SUVChangeVSBaseline>() { SUVChangeVSBaseline.Increase }),
Column3=ReadingCommon.EnumToString(new List<FDGAffinityFociInBM>() { FDGAffinityFociInBM.NE, FDGAffinityFociInBM.YesHaveNew, FDGAffinityFociInBM.YesSustain, FDGAffinityFociInBM.No}),
Column4=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMD }),
},
//3分/2分/1分/X NE/增大/减少/无明显变化 否 CMR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<PET5PSScore>() { PET5PSScore.Three,PET5PSScore.Two,PET5PSScore.One,PET5PSScore.X, }),
Column2=ReadingCommon.EnumToString(new List<SUVChangeVSBaseline>() { SUVChangeVSBaseline.NotEvaluable,SUVChangeVSBaseline.Increase,SUVChangeVSBaseline.Decrease,SUVChangeVSBaseline.DidNotChange, }),
Column3=ReadingCommon.EnumToString(new List<FDGAffinityFociInBM>() { FDGAffinityFociInBM.No}),
Column4=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.CMR }),
},
//3分/2分/1分/X NE/增大/减少/无明显变化 是，存在持续的局灶性变化 PMR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<PET5PSScore>() { PET5PSScore.Three,PET5PSScore.Two,PET5PSScore.One,PET5PSScore.X, }),
Column2=ReadingCommon.EnumToString(new List<SUVChangeVSBaseline>() { SUVChangeVSBaseline.NotEvaluable,SUVChangeVSBaseline.Increase,SUVChangeVSBaseline.Decrease,SUVChangeVSBaseline.DidNotChange, }),
Column3=ReadingCommon.EnumToString(new List<FDGAffinityFociInBM>() { FDGAffinityFociInBM.YesSustain }),
Column4=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMR }),
},
//5分/4分 减少 否/是，存在持续的局灶性变化 PMR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<PET5PSScore>() { PET5PSScore.Five,PET5PSScore.Four }),
Column2=ReadingCommon.EnumToString(new List<SUVChangeVSBaseline>() { SUVChangeVSBaseline.Decrease }),
Column3=ReadingCommon.EnumToString(new List<FDGAffinityFociInBM>() { FDGAffinityFociInBM.No, FDGAffinityFociInBM.YesSustain}),
Column4=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMR }),
},
//5分/4分 无明显变化 否/是，存在持续的局灶性变化 NMR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<PET5PSScore>() { PET5PSScore.Five,PET5PSScore.Four }),
Column2=ReadingCommon.EnumToString(new List<SUVChangeVSBaseline>() { SUVChangeVSBaseline.DidNotChange }),
Column3=ReadingCommon.EnumToString(new List<FDGAffinityFociInBM>() { FDGAffinityFociInBM.No, FDGAffinityFociInBM.YesSustain}),
Column4=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NMR }),
},
};
var resultdata = data.Where(x =>
(x.NotEq.Contains(1) ? !x.Column1.Contains(PET5PS) : x.Column1.Contains(PET5PS) || x.Column1.Count() == 0) &&
(x.NotEq.Contains(2) ? !x.Column2.Contains(UptakeChange) : x.Column2.Contains(UptakeChange) || x.Column2.Count() == 0) &&
(x.NotEq.Contains(3) ? !x.Column3.Contains(EvidenceFocalFDG) : x.Column3.Contains(EvidenceFocalFDG) || x.Column3.Count() == 0))
.Select(x => x.Column4.FirstOrDefault())
.FirstOrDefault();
return resultdata ?? string.Empty;
}

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Lugano/评估算法/8、影像学整体肿瘤评估-对应表更新.png
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Lugano/评估算法/8、影像学整体肿瘤评估代码.cs
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public async Task<string> GetImgOncology(ReadingCalculateDto inDto)
{
if (inDto.IsBaseLine)
{
return ImagingOverallAssessment_Lugano.NA.GetEnumInt();
}
//var imageQualityEvaluation = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.ImageQualityAssessment&&x.Answer.EqEnum(ImageQualityEvaluation.Abnormal)).FirstOrDefault();
//if (imageQualityEvaluation != null)
//{
// return ImagingOverallAssessment_Lugano.NE.GetEnumInt();
//}
// CTandMRI
var CTandMRIData = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.CTandMRI).Select(x => x.Answer).FirstOrDefault();
// FDGPET
var FDGPETData = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.FDGPET).Select(x => x.Answer).FirstOrDefault();
var baseLineTaskId = await GetBaseLineTaskId(inDto);
// lastFDGPET
var lastFDGPETData = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LastFDGPET).Select(x => x.Answer).FirstOrDefault();
List<CalculationDto> data = new List<CalculationDto>() {
//1、ND NE NE/NA ND
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.ND }),
},
//2、ND/PD/CR/NE/PR/SD PMD PMD/CMR/PMR/NMR/NE/NA PMD/PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.ND, CTMRIOverallAssessment.PD,CTMRIOverallAssessment.CR,CTMRIOverallAssessment.NE,CTMRIOverallAssessment.PR,CTMRIOverallAssessment.SD}),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMD, }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() {FDGPETOverallAssessment.PMD, FDGPETOverallAssessment.CMR,FDGPETOverallAssessment.PMR, FDGPETOverallAssessment.NMR, FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA }),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.PMDPD }),
},
//3、ND/PD/CR/NE/PR/SD NE PMD PMD/PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.ND, CTMRIOverallAssessment.PD,CTMRIOverallAssessment.CR,CTMRIOverallAssessment.NE,CTMRIOverallAssessment.PR,CTMRIOverallAssessment.SD}),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() {FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMD, }),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.PMDPD }),
},
//4、PD NE CMR/PMR/NMR/NE/NA PMD/PD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PD}),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE, }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.CMR,FDGPETOverallAssessment.PMR, FDGPETOverallAssessment.NMR, FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA }),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.PMDPD }),
},
//5、NE NE NE/NA NE
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.NE }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA }),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.NE }),
},
//6、CR/PR/SD/NE/ND/PD CMR CMR/PMR/NMR/PMD/NE/NA CMR/CR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.CR,CTMRIOverallAssessment.PR,CTMRIOverallAssessment.SD,CTMRIOverallAssessment.NE,CTMRIOverallAssessment.ND,CTMRIOverallAssessment.PD }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.CMR }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.CMR,FDGPETOverallAssessment.PMR, FDGPETOverallAssessment.NMR, FDGPETOverallAssessment.PMD, FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA }),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.CMRCR }),
},
//7、CR NE NE/NA CMR/CR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.CR }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA,}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.CMRCR }),
},
//8、 CR、PR、SD、NE、ND NE CMR CMR/CR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.CR,CTMRIOverallAssessment.PR,CTMRIOverallAssessment.SD,CTMRIOverallAssessment.NE,CTMRIOverallAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.CMR,}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.CMRCR }),
},
//9、ND/PD/CR/NE/PR/SD PMR PMD/CMR/PMR/NMR/NE/NA PMR/PR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.ND, CTMRIOverallAssessment.PD,CTMRIOverallAssessment.CR,CTMRIOverallAssessment.NE,CTMRIOverallAssessment.PR,CTMRIOverallAssessment.SD }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMR }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMD, FDGPETOverallAssessment.CMR,FDGPETOverallAssessment.PMR, FDGPETOverallAssessment.NMR, FDGPETOverallAssessment.NE,FDGPETOverallAssessment.NA, }),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.PMRPR }),
},
//10、PR NE NE/NA PMR/PR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.PR }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA,}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.PMRPR }),
},
//11、CR/PR/SD/NE/ND NE PMR PMR/PR
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.CR,CTMRIOverallAssessment.PR,CTMRIOverallAssessment.SD,CTMRIOverallAssessment.NE,CTMRIOverallAssessment.ND }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMR}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.PMRPR }),
},
//12、ND/PD/CR/NE/PR/SD NMR PMD/CMR/PMR/NMR/NE/NA NMR/SD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.ND,CTMRIOverallAssessment.PD,CTMRIOverallAssessment.CR,CTMRIOverallAssessment.NE,CTMRIOverallAssessment.PR,CTMRIOverallAssessment.SD }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NMR }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.PMD, FDGPETOverallAssessment.CMR, FDGPETOverallAssessment.PMR, FDGPETOverallAssessment.NMR, FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA,}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.NMRSD }),
},
//13、CR/PR/SD/ND/NE NE NMR NMR/SD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.CR, CTMRIOverallAssessment.PR, CTMRIOverallAssessment.SD, CTMRIOverallAssessment.ND, CTMRIOverallAssessment.NE }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NMR}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.NMRSD }),
},
//14、SD NE NE/NA NMR/SD
new CalculationDto(){
Column1=ReadingCommon.EnumToString(new List<CTMRIOverallAssessment>() { CTMRIOverallAssessment.SD }),
Column2=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE }),
Column3=ReadingCommon.EnumToString(new List<FDGPETOverallAssessment>() { FDGPETOverallAssessment.NE, FDGPETOverallAssessment.NA,}),
Column4=ReadingCommon.EnumToString(new List<ImagingOverallAssessment_Lugano>() { ImagingOverallAssessment_Lugano.NMRSD }),
},
};
var resultdata = data.Where(x =>
(x.NotEq.Contains(1) ? !x.Column1.Contains(CTandMRIData) : x.Column1.Contains(CTandMRIData) || x.Column1.Count() == 0) &&
(x.NotEq.Contains(2) ? !x.Column2.Contains(FDGPETData) : x.Column2.Contains(FDGPETData) || x.Column2.Count() == 0) &&
(x.NotEq.Contains(3) ? !x.Column3.Contains(lastFDGPETData) : x.Column3.Contains(lastFDGPETData) || x.Column3.Count() == 0))
.Select(x => x.Column4.FirstOrDefault())
.FirstOrDefault();
return resultdata ?? string.Empty;
}

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Lugano/评估算法/PET5PS评分.cs
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if(如果没有PET)
{
"NE";
}
else if(本访视病灶的 max SUVmax（所有病灶中最大的）> 2 * 肝脏血池SUVmax)
{
"5";
}
else if(本访视病灶的SUVmax（所有病灶中最大的）>肝脏血池SUVmax)
{
"4";
}
else if(纵隔血池SUVmax<本访视点病灶的max SUVmax（所有病灶中最大的）≤1*肝脏血池SUVmax)
{
"3";
}
else if(本访视点病灶的SUVmax（所有病灶中最大的）<纵隔血池SUVmax)
{
"2";
}
else
{
"";//原来是1这里改为空
}

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Lugano/评估算法/与基线相比摄取值变化.cs
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if(本访视无PET图像)
{
"NE";
}
else if(本访视PET评分 > 基线PET评分)
{
"增大";
}
else if(本访视PET评分 < 基线PET评分)
{
"减小";
}
else if(访视PET评分 = 基线PET评分)
{
"不赋值，为空";
}

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Lugano/评估算法/普通靶病灶的疾病进展状态 - 前端.cs
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// LDi LDi= 当前病灶的长径
// LDi LDi= 当前病灶的短径
// PPD PPD= 当前病灶的PPD
if( 15mm < 当前靶病灶LDi ≤20mm && 相比最低点PPD增加百分比 ≥50％ && (相比PPD最低点LDi增加值 ≥5 mm || 相比PPD最低点SDi增加值≥5 mm) )
{
// 疾病进展
}
else if( 当前靶病灶LDi>20 mm && 相比最低点PPD增加百分比 ≥50％ (相比PPD最低点LDi增加值 ≥10 mm || 相比PPD最低点SDi增加值Sdi ≥10 mm))
{
// 疾病进展
}

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Lugano/评估算法/脾脏状态.cs
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if(当前垂直径 ==0)
{
"无法评估"
}else if（当前垂直径≤130mm）
{
"正常";
}
else if(当前访视是基线)
{
"肿大"
}else
{
if(基线 垂直径> 130 mm && 与基线相比脾垂直径变化值≥10 mm && 与基线相比脾肿大增加的百分比 > 50％)
{
"显著增大";
}
else if(基线 垂直径> 130 mm
&& 当前访视的前面访视中 存在垂直径≤130mm
&& 与最低点相比脾脏垂直径的增加值≥20 mm
&& 当前垂直径 > 130 mm)
{
"显著增大";
}
else if(基线垂直径≤130mm && 与基线相比脾垂直径变化值≥20 mm && 当前垂直径 > 130 mm)
{
"显著增大";
}
else if(基线期 状态为“肿大”
&& 与基线相比脾肿大增加的百分比 < -50％)
{
"部分缓解";
}
else
{
"稳定";
}
}
注：
1、与基线相比脾肿大增加的百分比的计算方式：
（1）当前垂直径大于130，且基线垂直径大于130时，=[（当前垂直径-130）-（基线垂直径-130）]/（基线垂直径-130）；
（2）当前垂直径小于等于130，或者基线垂直径小于等于130时，赋值NA
2、与基线相比脾垂直径变化值的计算方式：当前访视脾脏垂直径-基线脾脏垂直径

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Lugano/评估算法/融合靶病灶的疾病进展状态 - 前端.cs
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// LDi LDi= 当前病灶的长径
// LDi LDi= 当前病灶的短径
// PPD PPD= 当前病灶的PPD
if( 15mm < 当前靶病灶LDi && 相比最低点PPD增加百分比 ≥50％ )
{
// 疾病进展
}

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Lugano/评估算法/靶病灶分裂主病灶的疾病进展状态.cs
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// LDi LDi= 主病灶加分裂病灶的长径之和
// LDi LDi= 主病灶加分裂病灶的短径之和
// PPD PPD= 主病灶加分裂病灶的PPD之和
if( 15mm < 当前靶病灶LDi≤20mm && 相比最低点PPD增加百分比 ≥50％ && (相比PPD最低点LDi增加值 ≥5 mm || 相比PPD最低点SDi增加值≥5 mm) )
{
// 疾病进展
}
else if( 当前靶病灶LDi>20 mm && 相比最低点PPD增加百分比 ≥50％ (相比PPD最低点LDi增加值 ≥10 mm || 相比PPD最低点SDi增加值Sdi ≥10 mm))
{
// 疾病进展
}
else if
(
if(之前是疾病进展)
{
// 改为存在
}
)

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Lugano/评估算法/靶病灶融合主病灶的疾病进展状态.cs
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// LDi LDi= 当前病灶的长径
// LDi LDi= 当前病灶的短径
// PPD PPD= 当前病灶的PPD
if( 15mm < 当前靶病灶LDi && 相比最低点PPD增加百分比 ≥50％ )
{
// 疾病进展
}

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Lugano/评估算法/骨髓中是否存在局灶性 FDG亲和病灶的证据.cs
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if(不存在PET)
{
"NE"
}
else
{
"取骨髓中是否存在局灶性 FDG亲和病灶的证据 的结果"
}

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