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{"sheet":"整体肿瘤评估逻辑","index":0,"n_rows":121,"n_cols":4,"rows_kept":121}
["靶病灶","非靶病灶","新病灶","整体疗效"]
["CR","CR","是","PD"]
["CR","CR","否","CR"]
["CR","CR","疑似","PR"]
["CR","CR","NE","PR"]
["CR","ND","是","PD"]
["CR","ND","否","CR"]
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["CR","PD","是","PD"]
["CR","PD","否","PD"]
["CR","PD","疑似","PD"]
["CR","PD","NE","PD"]
["PR","CR","是","PD"]
["PR","CR","否","PR"]
["PR","CR","疑似","PR"]
["PR","CR","NE","PR"]
["PR","ND","是","PD"]
["PR","ND","否","PR"]
["PR","ND","疑似","PR"]
["PR","ND","NE","PR"]
["PR","NE","是","PD"]
["PR","NE","否","PR"]
["PR","NE","疑似","PR"]
["PR","NE","NE","PR"]
["PR","NN","是","PD"]
["PR","NN","否","PR"]
["PR","NN","疑似","PR"]
["PR","NN","NE","PR"]
["PR","PD","是","PD"]
["PR","PD","否","PD"]
["PR","PD","疑似","PD"]
["PR","PD","NE","PD"]
["SD","CR","是","PD"]
["SD","CR","否","SD"]
["SD","CR","疑似","SD"]
["SD","CR","NE","SD"]
["SD","ND","是","PD"]
["SD","ND","否","SD"]
["SD","ND","疑似","SD"]
["SD","ND","NE","SD"]
["SD","NE","是","PD"]
["SD","NE","否","SD"]
["SD","NE","疑似","SD"]
["SD","NE","NE","SD"]
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["SD","NN","否","SD"]
["SD","NN","疑似","SD"]
["SD","NN","NE","SD"]
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["PD","NE","疑似","PD"]
["PD","NE","NE","PD"]
["PD","NN","是","PD"]
["PD","NN","否","PD"]
["PD","NN","疑似","PD"]
["PD","NN","NE","PD"]
["PD","PD","是","PD"]
["PD","PD","否","PD"]
["PD","PD","疑似","PD"]
["PD","PD","NE","PD"]
["ND","CR","是","PD"]
["ND","CR","否","CR"]
["ND","CR","疑似","PR"]
["ND","CR","NE","PR"]
["ND","ND","是","PD"]
["ND","ND","否","ND"]
["ND","ND","疑似","ND"]
["ND","ND","NE","NE"]
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["ND","NN","NE","NN"]
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["ND","PD","否","PD"]
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["ND","PD","NE","PD"]
["NE","CR","是","PD"]
["NE","CR","否","NE"]
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["NE","ND","否","NE"]
["NE","ND","疑似","NE"]
["NE","ND","NE","NE"]
["NE","NE","是","PD"]
["NE","NE","否","NE"]
["NE","NE","疑似","NE"]
["NE","NE","NE","NE"]
["NE","NN","是","PD"]
["NE","NN","否","NE"]
["NE","NN","疑似","NE"]
["NE","NN","NE","NE"]
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["NE","PD","否","PD"]
["NE","PD","疑似","PD"]
["NE","PD","NE","PD"]

{"sheet":"靶病灶评估逻辑","index":1,"n_rows":17,"n_cols":8,"rows_kept":17}
["之前的整体肿瘤评估访视点","SOD变化的百分比","非淋巴结靶病灶长径之和","SOD的绝对值变化","所有淋巴结靶病灶的短径","被评估为NE的单个靶病灶","靶病灶评估","其他条件"]
["不限","N/A","0 mm（全部消失）","N/A","N/A","无","CR","N/A"]
["不限","与基线期SOD相比减小≥30%以及与整体访视期间最低点SOD相比增加＜20%","N/A","N/A","N/A","无","PR"]
["不限","与基线期SOD相比减小≥30%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","无","PR"]
["不限","与基线期SOD相比减小＜30%并且与整体访视期间最低点SOD相比增大＜20%。","N/A","N/A","N/A","无","SD"]
["不限","与基线期SOD相比减小＜30%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","无","SD"]
["不限","比整体访视期间最低点SOD增加≥20%","N/A","比整体访视期间最低点SOD绝对增加值≥5 mm","N/A","N/A","PD"]
["不限","与整体访视期间最低点相比增长< 20%","N/A","N/A","N/A","有","NE"]
["不限","与整体访视期间最低点相比增长≥ 20%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","有","NE"]
["不限","NA","NA","N/A","N/A","无","ND"]
[]
["特殊情况"]
["上次访视点整体肿瘤评估","当前访视点非淋巴结病灶","当前访视点淋巴结病灶","与上次访视点相比增长量","预期靶病灶的评估"]
["CR","N/A","N/A","N/A","PD"]
["CR","至少一个非淋巴结靶病灶的长径＞0 mm。","N/A","N/A","PD"]
[]
["注意最低点SOD不为0，但是有时CR的情况"]

{"sheet":"非靶病灶评估逻辑","index":2,"n_rows":6,"n_cols":3,"rows_kept":6}
["单个非靶病灶评估","非靶病灶评估"]
["任意单个病灶/病灶组评估为“显著增大”","PD","√"]
["任意单个病灶/病灶组评估为“无法评估”并且没有“显著增大”","NE","√"]
["所有单个病灶/病灶组评估为”存在”或者有些评估为“消失”有些评估为“存在”,且没有“显著增大”和“无法评估”的病灶","非CR/非PD（NN）","√"]
["所有单个病灶/病灶组状态评估状态为“消失”","CR","√"]
["基线时没有非靶病灶","ND"]

{"sheet":"新病灶评估逻辑","index":3,"n_rows":5,"n_cols":3,"rows_kept":5}
["单个新病灶评估","是否存在新病灶"]
["当前访视存在至少一个明确新病灶","是","√"]
["排除是的情况后，只要有任何一个新病灶状态为“无法评估”","NE","√"]
["排除是和NE的情况后，当前访视不存在明确新病灶且存在至少一个疑似新病灶","疑似","√"]
["不存在上述三种已定义的新病灶状态","否","√"]

{"sheet":"Sheet1","index":4,"n_rows":60,"n_cols":4,"rows_kept":60}
[null,"基线","上一次访视","本次访视"]
["靶病灶径线之和（SOD）","50（5个淋巴结靶病灶，短径都为9）"]
["非淋巴结靶病灶长径之和"]
["与基线相比SOD变化量"]
["与基线相比SOD变化百分比"]
["与最低点相比SOD变化量"]
["与最低点相比SOD变化百分比"]
["最低点访视"]
["最低点访视SOD",null,"45（5个淋巴结靶病灶，短径都为9）","14（一个淋巴结靶病灶，短径为13）"]
["存在非淋巴结靶病灶"]
["存在淋巴结靶病灶且比上一访视短径增加5mm以上"]
["存在被评估为NE的单个靶病灶","否","否","是"]
["淋巴结非靶病灶数量",0,0,0]
["靶病灶评估"]
["非靶病灶评估"]
["存在新病灶"]
["存在疾病"]
["整体肿瘤评估",null,"CR","PR"]
["访视点备注"]
[]
[]
[null,"基线","上一次访视","本次访视"]
["靶病灶径线之和（SOD）","50（5个淋巴结靶病灶，短径都为9）"]
["非淋巴结靶病灶长径之和"]
["与基线相比SOD变化量"]
["与基线相比SOD变化百分比"]
["与最低点相比SOD变化量"]
["与最低点相比SOD变化百分比"]
["最低点访视"]
["最低点访视SOD",null,"45（5个淋巴结靶病灶，短径都为9）","14（一个淋巴结靶病灶，短径为13）"]
["存在非淋巴结靶病灶"]
["存在淋巴结靶病灶且比上一访视短径增加5mm以上"]
["存在被评估为NE的单个靶病灶","否","否","是"]
["淋巴结非靶病灶数量",0,0,0]
["靶病灶评估"]
["非靶病灶评估"]
["存在新病灶"]
["存在疾病"]
["整体肿瘤评估",null,"CR","NE"]
["访视点备注"]
[]
[null,"基线","上一次访视","本次访视"]
["靶病灶径线之和（SOD）","50（5个淋巴结靶病灶，短径都为9）"]
["非淋巴结靶病灶长径之和"]
["与基线相比SOD变化量"]
["与基线相比SOD变化百分比"]
["与最低点相比SOD变化量"]
["与最低点相比SOD变化百分比"]
["最低点访视"]
["最低点访视SOD",null,"45（5个淋巴结靶病灶，短径都为9）","8（一个淋巴结靶病灶，短径为8）"]
["存在非淋巴结靶病灶"]
["存在淋巴结靶病灶且比上一访视短径增加5mm以上"]
["存在被评估为NE的单个靶病灶","否","否","是"]
["淋巴结非靶病灶数量",0,0,0]
["靶病灶评估"]
["非靶病灶评估"]
["存在新病灶"]
["存在疾病"]
["整体肿瘤评估",null,"CR","CR"]
["访视点备注"]

{"sheet":"靶病灶评估逻辑-演练使用","index":5,"n_rows":24,"n_cols":7,"rows_kept":24}
["之前的整体肿瘤评估访视点","SOD变化的百分比","非淋巴结靶病灶长径之和","SOD的绝对值变化","所有淋巴结靶病灶的短径","被评估为NE的单个靶病灶","靶病灶评估"]
["不限","N/A","0 mm（全部消失）","N/A","所有短径<10 mm","无","CR"]
["不限","与基线期SOD相比减小≥30%以及与整体访视期间最低点SOD相比增加＜20%","N/A","N/A","N/A","无","PR"]
["不限","与基线期SOD相比减小≥30%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","无","PR"]
["不限","与基线期SOD相比减小＜30%并且与整体访视期间最低点SOD相比增大＜20%。","N/A","N/A","N/A","无","SD"]
["不限","与基线期SOD相比减小＜30%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","无","SD"]
["不限","N/A","0 mm（全部消失）","N/A","所有短径<10 mm","有","NE"]
["不限","与基线期SOD相比减小≥30%以及与整体访视期间最低点SOD相比增加＜20%","N/A","N/A","N/A","有","NE"]
["不限","与基线期SOD相比减小≥30%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","有","NE"]
["不限","与基线期SOD相比减小＜30%并且与整体访视期间最低点SOD相比增大＜20%。","N/A","N/A","N/A","有","NE"]
["不限","与基线期SOD相比减小＜30%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","有","NE"]
["不限","比整体访视期间最低点SOD增加≥20%","N/A","比整体访视期间最低点SOD绝对增加值≥5 mm","N/A","N/A","PD"]
["不限","与整体访视期间最低点相比增长< 20%","N/A","N/A","N/A","无","SD"]
["不限","与整体访视期间最低点相比增长≥ 20%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","无","SD"]
["不限","与整体访视期间最低点相比增长< 20%","N/A","N/A","N/A","有","NE"]
["不限","与整体访视期间最低点相比增长≥ 20%","N/A","比整体访视期间最低点SOD绝对增加值＜5 mm","N/A","有","NE"]
["不限","NA","NA","N/A","N/A","无","ND"]
[]
[]
[]
[]
["上次访视点整体肿瘤评估","当前访视点非淋巴结病灶","当前访视点淋巴结病灶","与上次访视点相比增长量","预期靶病灶的评估"]
["CR","N/A","至少一个淋巴结靶病灶短径≥10 mm","该淋巴结靶病灶短径绝对增加值≥5 mm","PD"]
["CR","至少一个非淋巴结靶病灶的长径＞0 mm。","N/A","N/A","PD"]