diff --git a/IRaCIS.Core.Application/IRaCIS.Core.Application.xml b/IRaCIS.Core.Application/IRaCIS.Core.Application.xml
index 2c718faa0..732a51c8a 100644
--- a/IRaCIS.Core.Application/IRaCIS.Core.Application.xml
+++ b/IRaCIS.Core.Application/IRaCIS.Core.Application.xml
@@ -826,6 +826,57 @@
             <param name="inDto"></param>
             <returns></returns>
         </member>
+        <member name="M:IRaCIS.Core.Application.Service.ReadingCalculate.PCWG3CalculateService.TestCalculate(System.Guid,IRaCIS.Core.Domain.Share.QuestionType)">
+            <summary>
+            测试计算
+            </summary>
+            <param name="visitTaskId"></param>
+            <param name="type"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ReadingCalculate.PCWG3CalculateService.CalculateTask(IRaCIS.Core.Application.Service.Reading.Dto.CalculateTaskInDto)">
+            <summary>
+            计算任务
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ReadingCalculate.PCWG3CalculateService.ReadingCalculate(IRaCIS.Core.Application.Service.Reading.Dto.ReadingCalculateDto,System.Collections.Generic.List{IRaCIS.Core.Domain.Share.QuestionType})">
+            <summary>
+            自动计算
+            </summary>
+            <param name="inDto"></param>
+            <param name="calculateType"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ReadingCalculate.PCWG3CalculateService.GetBaseLineLesionsCount(IRaCIS.Core.Application.Service.Reading.Dto.ReadingCalculateDto)">
+            <summary>
+            基线病灶计数
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ReadingCalculate.PCWG3CalculateService.GetNewLesionsCount(IRaCIS.Core.Application.Service.Reading.Dto.ReadingCalculateDto)">
+            <summary>
+            获取新病灶计数
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ReadingCalculate.PCWG3CalculateService.GetAlwaysNewLesionsCount(IRaCIS.Core.Application.Service.Reading.Dto.ReadingCalculateDto)">
+            <summary>
+            既往新病灶计数
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ReadingCalculate.PCWG3CalculateService.GetNewBoneLesionCount(IRaCIS.Core.Application.Service.Reading.Dto.ReadingCalculateDto)">
+            <summary>
+            自治疗后第二个访视点以来持续的新骨病变数量
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
         <member name="F:IRaCIS.Core.Application.Service.ReadingCalculate.ReadingCalculateService.CalculateServiceDic">
             <summary>
             标准和服务对应
@@ -2026,6 +2077,11 @@
             项目Id
             </summary>
         </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetReadingQuestionAndAnswerOutDto.BlindName">
+            <summary>
+            任务盲态名称 和访视盲态一样
+            </summary>
+        </member>
         <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.TrialReadQuestionData.PageName">
             <summary>
             分页名称
diff --git a/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs b/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs
index e1ba5a1de..913d45972 100644
--- a/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs
+++ b/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs
@@ -84,7 +84,7 @@ namespace IRaCIS.Core.Application.ViewModel
 
         public string FromName { get; set; } = string.Empty;
 
-        public string FromEmail { get; set; }
+        public string FromEmail { get; set; } = string.Empty;
 
 
         public List<Guid> ToUserIdList { get; set; }
diff --git a/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs b/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs
index 96706be7a..1b791345a 100644
--- a/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs
+++ b/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs
@@ -144,7 +144,7 @@ namespace IRaCIS.Core.Application.Service
 
 
 
-        private async Task<bool> FillWordTemplateAndSetEmailAsync(Guid visitTaskId, SMTPEmailConfig sendEmailConfig, CommonDocumentBusinessScenario businessScenarioEnum, string  fileName,string filePath)
+        private async Task<bool> FillWordTemplateAndSetEmailAsync(Guid visitTaskId, SMTPEmailConfig sendEmailConfig, CommonDocumentBusinessScenario businessScenarioEnum, string  fileName,string templatePath)
         {
 
             var isNeedSend = true;
@@ -464,16 +464,30 @@ namespace IRaCIS.Core.Application.Service
             if (isNeedSend)
             {
 
-                var docFileStream = System.IO.File.OpenRead(fileName);
-
+
+                var value = new Dictionary<string, object>()
+                {
+                    ["SponsorName"] = documentNeedBasicInfo.SponsorName,
+                    ["ResearchProgramNo"] = documentNeedBasicInfo.ResearchProgramNo,
+                    ["TrialSiteCode"] = documentNeedBasicInfo.TrialSiteCode,
+                    ["SubjectCode"] = documentNeedBasicInfo.SubjectCode,
+                    ["VisitName"] = documentNeedBasicInfo.VisitName,
+                    ["EarliestScanDate"] = documentNeedBasicInfo.SourceSubjectVisitId!=null?   documentNeedBasicInfo.VisitEarliestScanDate: documentNeedBasicInfo.ModuleEarliestScanDate,
+                    ["SignTime"] = documentNeedBasicInfo.SignTime,
+                    ["Result"] = answer
+
+                };
+
+                MemoryStream memoryStream = new MemoryStream();
 
 
+                MiniSoftware.MiniWord.SaveAsByTemplate(memoryStream, templatePath, value);
 
                 sendEmailConfig.EmailAttachMentConfigList.Add(new EmailAttachMentConfig()
                 {
                     FileName = fileName,
 
-                    FileStream = docFileStream
+                    FileStream = memoryStream
                 });
 
                 return false;