diff --git a/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs b/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs
index 82065c085..d28aee800 100644
--- a/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs
+++ b/IRaCIS.Core.Application/Service/Document/DTO/TrialEmailNoticeConfigViewModel.cs
@@ -22,8 +22,39 @@ namespace IRaCIS.Core.Application.ViewModel
         public DateTime CreateTime { get; set; }
 
         public Guid CreateUserId { get; set; }
+
+
+        public List<EmailUserInfoDto> TrialEmailNoticeUserList { get; set; }
+
+
+        public new Guid FromUserId => TrialEmailNoticeUserList.Where(t => t.EmailUserType == EmailUserType.From).Select(t => t.UserId).FirstOrDefault();
+        public new List<Guid> ToUserIdList => TrialEmailNoticeUserList.Where(t => t.EmailUserType == EmailUserType.To).Select(t => t.UserId).ToList();
+        public new List<Guid> CopyUserIdList => TrialEmailNoticeUserList.Where(t => t.EmailUserType == EmailUserType.Copy).Select(t => t.UserId).ToList();
+
+
     }
 
+
+    public  class EmailUserInfoDto
+    {
+        public Guid UserId { get; set; }
+
+        public Guid TrialEmailNoticeConfigId { get; set; }
+
+
+        public EmailUserType EmailUserType { get; set; }
+
+
+        public string Email { get; set; }
+
+        public string UserName { get; set; }
+
+        public string RealName { get; set; }
+    }
+
+
+
+
     ///<summary>TrialEmailNoticeConfigQuery  列表查询参数模型</summary>
     public class TrialEmailNoticeConfigQuery
     {
@@ -51,14 +82,21 @@ namespace IRaCIS.Core.Application.ViewModel
 
         public CriterionType CriterionTypeEnum { get; set; }
 
-        public List<string> ReceiveEmailList { get; set; }
-        public List<string> CopyEmailList { get; set; }
 
-        [JsonIgnore]
-        public string ReceiveEmailsStr { get; set; } = string.Empty;
+        public Guid FromUserId { get; set; }
+        public List<Guid> ToUserIdList { get; set; }
+        public List<Guid> CopyUserIdList { get; set; }
 
-        [JsonIgnore]
-        public string CopyEmailsStr { get; set; } = string.Empty;
+
+
+        //public List<string> ReceiveEmailList { get; set; }
+        //public List<string> CopyEmailList { get; set; }
+
+        //[JsonIgnore]
+        //public string ReceiveEmailsStr { get; set; } = string.Empty;
+
+        //[JsonIgnore]
+        //public string CopyEmailsStr { get; set; } = string.Empty;
 
 
         public string FromEmail { get; set; } = string.Empty;
diff --git a/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs b/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs
index 4c5540187..9ac53e337 100644
--- a/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs
+++ b/IRaCIS.Core.Application/Service/Document/TrialEmailNoticeConfigService.cs
@@ -23,9 +23,14 @@ namespace IRaCIS.Core.Application.Service
 
         private readonly IRepository<TrialEmailNoticeConfig> _trialEmailNoticeConfigRepository;
 
-        public TrialEmailNoticeConfigService(IRepository<TrialEmailNoticeConfig> trialEmailNoticeConfigRepository)
+        public IRepository<VisitTask> _visitTaskRepository { get; }
+        public IRepository<TrialUser> _trialUserRepository { get; }
+
+        public TrialEmailNoticeConfigService(IRepository<TrialEmailNoticeConfig> trialEmailNoticeConfigRepository, IRepository<VisitTask> visitTaskRepository,IRepository<TrialUser> trialUserRepository)
         {
             _trialEmailNoticeConfigRepository = trialEmailNoticeConfigRepository;
+            _visitTaskRepository = visitTaskRepository;
+            _trialUserRepository = trialUserRepository;
         }
 
 
@@ -86,22 +91,22 @@ namespace IRaCIS.Core.Application.Service
 
             var sendEmailConfig = new SMTPEmailConfig();
 
-            foreach (var item in emailConfig.ReceiveEmailList)
-            {
-                sendEmailConfig.ToMailAddressList.Add(new MimeKit.MailboxAddress(item, item));
-            }
+            //foreach (var item in emailConfig.ReceiveEmailList)
+            //{
+            //    sendEmailConfig.ToMailAddressList.Add(new MimeKit.MailboxAddress(item, item));
+            //}
 
-            foreach (var item in emailConfig.CopyEmailList)
-            {
-                if (item.Contains("@") && !string.IsNullOrEmpty(item))
-                {
-                    sendEmailConfig.CopyToMailAddressList.Add(new MimeKit.MailboxAddress(item.Trim(), item.Trim()));
-                }
-            }
+            //foreach (var item in emailConfig.CopyEmailList)
+            //{
+            //    if (item.Contains("@") && !string.IsNullOrEmpty(item))
+            //    {
+            //        sendEmailConfig.CopyToMailAddressList.Add(new MimeKit.MailboxAddress(item.Trim(), item.Trim()));
+            //    }
+            //}
 
 
             //邮件内容html
-            await FillWordTemplateAndSetEmailAsync(sendEmailConfig, businessScenarioEnum, criterionTypeEnum!);
+            await FillWordTemplateAndSetEmailAsync(visitTaskId, sendEmailConfig, businessScenarioEnum, criterionTypeEnum!);
 
             //邮件附件
             var path = FileStoreHelper.GetPhysicalFilePath(_hostEnvironment, emailConfig.FilePath);
@@ -126,7 +131,7 @@ namespace IRaCIS.Core.Application.Service
 
 
 
-        private async Task FillWordTemplateAndSetEmailAsync(SMTPEmailConfig sendEmailConfig, CommonDocumentBusinessScenario businessScenarioEnum, CriterionType criterionType)
+        private async Task FillWordTemplateAndSetEmailAsync(Guid visitTaskId, SMTPEmailConfig sendEmailConfig, CommonDocumentBusinessScenario businessScenarioEnum, CriterionType criterionType)
         {
             var pathToFile = _hostEnvironment.WebRootPath
                        + Path.DirectorySeparatorChar.ToString()
@@ -152,11 +157,15 @@ namespace IRaCIS.Core.Application.Service
 
                 switch (criterionType)
                 {
-                   
+
                     case CriterionType.SelfDefine:
                         break;
 
                     case CriterionType.RECIST1Pointt1:
+
+
+                        //_visitTaskRepository.Where(t => t.Id == visitTaskId).Select(t => new { t.Trial.ResearchProgramNo, t.Subject.TrialSite.TrialSiteCode, SubjectCode = t.Subject.Code, VisitEarliestScanDate = t.SourceSubjectVisit.EarliestScanDate, t.sou })
+
                         break;
 
                     case CriterionType.PCWG3:
@@ -195,7 +204,7 @@ namespace IRaCIS.Core.Application.Service
                 }
 
 
-               
+
 
 
             }
@@ -220,6 +229,7 @@ namespace IRaCIS.Core.Application.Service
                     case CriterionType.SelfDefine:
                         break;
                     case CriterionType.RECIST1Pointt1:
+
                         break;
                     case CriterionType.PCWG3:
                         break;
@@ -258,6 +268,8 @@ namespace IRaCIS.Core.Application.Service
         }
 
 
+
+
         [HttpPost]
         public async Task<List<TrialEmailNoticeConfigView>> GetTrialEmailNoticeConfigList(TrialEmailNoticeConfigQuery inQuery)
         {
@@ -276,12 +288,57 @@ namespace IRaCIS.Core.Application.Service
         public async Task<IResponseOutput> AddOrUpdateTrialEmailNoticeConfig(TrialEmailNoticeConfigAddOrEdit addOrEditTrialEmailNoticeConfig)
         {
 
-            addOrEditTrialEmailNoticeConfig.ReceiveEmailsStr = String.Join('|', addOrEditTrialEmailNoticeConfig.ReceiveEmailList);
-            addOrEditTrialEmailNoticeConfig.CopyEmailsStr = String.Join('|', addOrEditTrialEmailNoticeConfig.CopyEmailList);
+            List<TrialEmailNoticeUser> trialEmailNoticeUsers = new List<TrialEmailNoticeUser>();
 
-            var entity = await _trialEmailNoticeConfigRepository.InsertOrUpdateAsync(addOrEditTrialEmailNoticeConfig, true);
 
-            return ResponseOutput.Ok(entity.Id.ToString());
+
+            trialEmailNoticeUsers.Add(new TrialEmailNoticeUser() { EmailUserType = EmailUserType.From, UserId = addOrEditTrialEmailNoticeConfig.FromUserId });
+
+
+            foreach (var item in addOrEditTrialEmailNoticeConfig.ToUserIdList)
+            {
+                trialEmailNoticeUsers.Add(new TrialEmailNoticeUser() { EmailUserType = EmailUserType.To, UserId = item });
+
+            }
+
+            foreach (var item in addOrEditTrialEmailNoticeConfig.CopyUserIdList)
+            {
+                trialEmailNoticeUsers.Add(new TrialEmailNoticeUser() { EmailUserType = EmailUserType.Copy, UserId = item });
+
+            }
+
+            //var entity = await _trialEmailNoticeConfigRepository.InsertOrUpdateAsync(addOrEditTrialEmailNoticeConfig);
+
+            if (addOrEditTrialEmailNoticeConfig.Id == null)
+            {
+
+                var entity = _mapper.Map<TrialEmailNoticeConfig>(addOrEditTrialEmailNoticeConfig);
+
+
+                entity.TrialEmailNoticeUserList = trialEmailNoticeUsers;
+
+
+                 await _trialEmailNoticeConfigRepository.AddAsync(entity, true);
+
+                return ResponseOutput.Ok(entity.Id.ToString());
+
+
+
+            }
+            else
+            {
+                await _repository.BatchDeleteAsync<TrialEmailNoticeUser>(t => t.TrialEmailNoticeConfigId == addOrEditTrialEmailNoticeConfig.Id);
+
+
+                var entity = (await _trialEmailNoticeConfigRepository.Where(t => t.Id == addOrEditTrialEmailNoticeConfig.Id, true, true).Include(t => t.TrialEmailNoticeUserList).FirstOrDefaultAsync()).IfNullThrowException();
+
+                await _repository.AddRangeAsync(trialEmailNoticeUsers);
+
+                await _trialEmailNoticeConfigRepository.SaveChangesAsync();
+
+                return ResponseOutput.Ok();
+            }
+
 
         }
 
diff --git a/IRaCIS.Core.Application/Service/Document/_MapConfig.cs b/IRaCIS.Core.Application/Service/Document/_MapConfig.cs
index b429f86dc..dbfe62d1a 100644
--- a/IRaCIS.Core.Application/Service/Document/_MapConfig.cs
+++ b/IRaCIS.Core.Application/Service/Document/_MapConfig.cs
@@ -69,10 +69,17 @@ namespace IRaCIS.Core.Application.Service
                .ForMember(d => d.SystemDocumentId, c => c.Ignore());
 
 
-            CreateMap<TrialEmailNoticeConfig, TrialEmailNoticeConfigView>();
+            CreateMap<TrialEmailNoticeConfig, TrialEmailNoticeConfigView>()
+                 .ForMember(d => d.TrialEmailNoticeUserList, c => c.MapFrom(t => t.TrialEmailNoticeUserList));
 
             CreateMap<TrialEmailNoticeConfigAddOrEdit, TrialEmailNoticeConfig>();
 
+
+            CreateMap<TrialEmailNoticeUser, EmailUserInfoDto>()
+                .ForMember(d => d.Email, c => c.MapFrom(t => t.User.EMail))
+                 .ForMember(d => d.RealName, c => c.MapFrom(t => t.User.FullName))
+                .ForMember(d => d.UserName, c => c.MapFrom(t => t.User.UserName));
+
         }
     }
 
diff --git a/IRaCIS.Core.Domain.Share/Common/EmailScenarioEnum.cs b/IRaCIS.Core.Domain.Share/Common/EmailScenarioEnum.cs
index 5e893cbec..ff9a048eb 100644
--- a/IRaCIS.Core.Domain.Share/Common/EmailScenarioEnum.cs
+++ b/IRaCIS.Core.Domain.Share/Common/EmailScenarioEnum.cs
@@ -47,6 +47,15 @@ namespace IRaCIS.Core.Domain.Share
     }
 
 
+    public enum EmailUserType
+    {
+        From =1,
+
+        To=2,
+
+        Copy=3
+    }
+
 
 
     public enum BasicDataTypeEnum
diff --git a/IRaCIS.Core.Domain/Allocation/VisitTask.cs b/IRaCIS.Core.Domain/Allocation/VisitTask.cs
index 4eb7de060..133399d50 100644
--- a/IRaCIS.Core.Domain/Allocation/VisitTask.cs
+++ b/IRaCIS.Core.Domain/Allocation/VisitTask.cs
@@ -215,6 +215,11 @@ namespace IRaCIS.Core.Domain.Models
 
         #endregion
 
+
+        [JsonIgnore]
+
+        public Trial Trial { get; set; }
+
         [JsonIgnore]
         public List<ReadingTaskQuestionAnswer> ReadingTaskQuestionAnswerList { get; set; } = new List<ReadingTaskQuestionAnswer>();
 
diff --git a/IRaCIS.Core.Domain/Document/TrialEmailNoticeConfig.cs b/IRaCIS.Core.Domain/Document/TrialEmailNoticeConfig.cs
index 8733b8fe1..e77d29ae0 100644
--- a/IRaCIS.Core.Domain/Document/TrialEmailNoticeConfig.cs
+++ b/IRaCIS.Core.Domain/Document/TrialEmailNoticeConfig.cs
@@ -26,15 +26,22 @@ namespace IRaCIS.Core.Domain.Models
 		public string AuthorizationCode { get; set; } = string.Empty;
 
 
-		public string ReceiveEmailsStr { get; set; } = string.Empty;
-		public string CopyEmailsStr { get; set; } = string.Empty;
+
+		public List<TrialEmailNoticeUser> TrialEmailNoticeUserList { get; set; } = new List<TrialEmailNoticeUser>();
 
 
-		[NotMapped]
-		public List<string> ReceiveEmailList => ReceiveEmailsStr.Split('|', StringSplitOptions.RemoveEmptyEntries).Where(t => !string.IsNullOrEmpty(t)).Select(t=>t.Trim()).ToList();
+		//[Required]
+		//public string FromEmail { get; set; }
+		//public string ReceiveEmailsStr { get; set; } = string.Empty;
+		//public string CopyEmailsStr { get; set; } = string.Empty;
+
+		//[NotMapped]
+		//public List<string> ReceiveEmailList => ReceiveEmailsStr.Split('|', StringSplitOptions.RemoveEmptyEntries).Where(t => !string.IsNullOrEmpty(t)).Select(t=>t.Trim()).ToList();
+
+		//[NotMapped]
+		//public List<string> CopyEmailList => CopyEmailsStr.Split('|', StringSplitOptions.RemoveEmptyEntries).Where(t=> !string.IsNullOrEmpty(t)).Select(t => t.Trim()).ToList();
+
 
-		[NotMapped]
-		public List<string> CopyEmailList => CopyEmailsStr.Split('|', StringSplitOptions.RemoveEmptyEntries).Where(t=> !string.IsNullOrEmpty(t)).Select(t => t.Trim()).ToList();
 
 		[Required]
 		public bool IsUrgent { get; set; }
@@ -48,8 +55,7 @@ namespace IRaCIS.Core.Domain.Models
 		[Required]
 		public bool IsReturnRequired { get; set; }
 
-		[Required]
-		public string FromEmail { get; set; }
+
 	
 		[Required]
 		public bool IsAutoSend { get; set; }
diff --git a/IRaCIS.Core.Domain/Document/TrialEmailNoticeUser.cs b/IRaCIS.Core.Domain/Document/TrialEmailNoticeUser.cs
new file mode 100644
index 000000000..eb79b29e1
--- /dev/null
+++ b/IRaCIS.Core.Domain/Document/TrialEmailNoticeUser.cs
@@ -0,0 +1,35 @@
+
+//--------------------------------------------------------------------
+//     此代码由T4模板自动生成  byzhouhang 20210918
+//	   生成时间 2022-10-21 16:06:20 
+//     对此文件的更改可能会导致不正确的行为，并且如果重新生成代码，这些更改将会丢失。
+using System;
+using IRaCIS.Core.Domain.Share;
+using System.ComponentModel.DataAnnotations;
+using System.ComponentModel.DataAnnotations.Schema;
+namespace IRaCIS.Core.Domain.Models
+{
+	 ///<summary>
+	 ///TrialEmailNoticeUser
+	 ///</summary>
+	 [Table("TrialEmailNoticeUser")]	
+	 public class TrialEmailNoticeUser : Entity
+	 {
+
+        [JsonIgnore]
+		public User User { get; set; }
+
+		[JsonIgnore]
+		public TrialEmailNoticeConfig TrialEmailNoticeConfig { get; set; }
+
+
+		public Guid UserId { get; set; }
+	
+
+		public Guid TrialEmailNoticeConfigId { get; set; }
+
+
+		public EmailUserType EmailUserType { get; set; }
+	}
+
+}	 
diff --git a/IRaCIS.Core.Infra.EFCore/Context/IRaCISDBContext.cs b/IRaCIS.Core.Infra.EFCore/Context/IRaCISDBContext.cs
index 16b46f940..e2565cb95 100644
--- a/IRaCIS.Core.Infra.EFCore/Context/IRaCISDBContext.cs
+++ b/IRaCIS.Core.Infra.EFCore/Context/IRaCISDBContext.cs
@@ -665,6 +665,7 @@ namespace IRaCIS.Core.Infra.EFCore
 
         public virtual DbSet<TrialEmailNoticeConfig> TrialEmailNoticeConfig { get; set; }
 
+        public virtual DbSet<TrialEmailNoticeUser> TrialEmailNoticeUser { get; set; }
 
 
     }
diff --git a/IRaCIS.Core.Test/DbHelper.ttinclude b/IRaCIS.Core.Test/DbHelper.ttinclude
index 050d882f1..6964fe06d 100644
--- a/IRaCIS.Core.Test/DbHelper.ttinclude
+++ b/IRaCIS.Core.Test/DbHelper.ttinclude
@@ -4,7 +4,7 @@
         public static readonly string ConnectionString = "Server=123.56.94.154,1433\\MSSQLSERVER;Database=IRaCIS_New_Tet;User ID=sa;Password=dev123456DEV;TrustServerCertificate=true";
         public static readonly string DbDatabase = "IRaCIS_New_Tet";
         //���������ַ���,ƴ��
-        public static readonly string TableName = "TrialEmailNoticeConfig";
+        public static readonly string TableName = "TrialEmailNoticeUser";
         //�����ļ�����  ����service ���������Ƿ��ҳ
 	}
 #>