diff --git a/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs b/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs
index 626f5effc..be1720087 100644
--- a/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs
@@ -17,6 +17,7 @@ using IRaCIS.Core.Application.Filter;
 using DocumentFormat.OpenXml.Drawing;
 using EasyCaching.Core;
 using DocumentFormat.OpenXml.Drawing.Charts;
+using IRaCIS.Core.Application.Service.ReadingCalculate.Interface;
 
 namespace IRaCIS.Application.Services
 {
@@ -48,7 +49,8 @@ namespace IRaCIS.Application.Services
         private readonly IRepository<TrialDocument> _trialDocumentRepository;
         private readonly IRepository<User> _userRepository;
         private readonly IEasyCachingProvider _provider;
-        private readonly IRepository<ReadingCustomTag> _readingCustomTagRepository;
+		private readonly ILuganoCalculateService _luganoCalculateService;
+		private readonly IRepository<ReadingCustomTag> _readingCustomTagRepository;
         private readonly IRepository<ReadingTaskQuestionMark> _readingTaskQuestionMarkRepository;
         private readonly IRepository<ReadingSystemCriterionDictionary> _readingCriterionDictionaryRepository;
         private readonly IRepository<ReadingTrialCriterionDictionary> _readingTrialCriterionDictionaryRepository;
@@ -88,7 +90,8 @@ namespace IRaCIS.Application.Services
                   IRepository<TrialDocument> trialDocumentRepository,
                   IRepository<User> userRepository,
                   IEasyCachingProvider provider,
-                  IRepository<ReadingCustomTag> readingCustomTagRepository,
+				  ILuganoCalculateService luganoCalculateService,
+				  IRepository<ReadingCustomTag> readingCustomTagRepository,
                   IRepository<ReadingTaskQuestionMark> readingTaskQuestionMarkRepository,
                   IRepository<ReadingSystemCriterionDictionary> readingCriterionDictionaryRepository,
                   IRepository<ReadingTrialCriterionDictionary> readingTrialCriterionDictionaryRepository,
@@ -126,7 +129,8 @@ namespace IRaCIS.Application.Services
             this._trialDocumentRepository = trialDocumentRepository;
             this._userRepository = userRepository;
             this._provider = provider;
-            this._readingCustomTagRepository = readingCustomTagRepository;
+			this._luganoCalculateService = luganoCalculateService;
+			this._readingCustomTagRepository = readingCustomTagRepository;
             this._readingTaskQuestionMarkRepository = readingTaskQuestionMarkRepository;
             this._readingCriterionDictionaryRepository = readingCriterionDictionaryRepository;
             this._tumorAssessmentRepository = tumorAssessmentRepository;
@@ -1808,9 +1812,7 @@ namespace IRaCIS.Application.Services
         public async Task<SubmitTableQuestionOutDto> SubmitTableQuestion(SubmitTableQuestionInDto inDto)
         {
             SubmitTableQuestionOutDto result = new SubmitTableQuestionOutDto();
-
             await VerifyTaskIsSign(inDto.VisitTaskId);
-
             if (inDto.InstanceId != null && inDto.IsDicomReading)
             {
                 if (!(await _dicomInstanceRepository.AnyAsync(x => x.Id == inDto.InstanceId && x.SeriesId == inDto.SeriesId)))
@@ -1968,24 +1970,20 @@ namespace IRaCIS.Application.Services
 
                     break;
             }
-
             var questionInfo = await _readingQuestionTrialRepository.Where(x => x.Id == inDto.QuestionId).FirstNotNullAsync();
             var criterionId = await _visitTaskRepository.Where(x => x.Id == inDto.VisitTaskId).Select(x => x.TrialReadingCriterionId).FirstOrDefaultAsync();
             var criterionInfo = await _readingQuestionCriterionTrialRepository.Where(x => x.Id == criterionId).FirstNotNullAsync();
             var tableQuestionIds = inDto.AnswerList.Select(x => x.TableQuestionId).ToList();
             var tableAnswerList = await _readingTableQuestionAnswerRepository.Where(x => x.RowId == inDto.RowId).ToListAsync();
-
             var tableQuestionIdGroup = tableQuestionIds.GroupBy(x => new { TableQuestionId = x }).Select(x => new TableQuestionData
             {
                 TableQuestionId = x.Key.TableQuestionId,
                 Count = x.Count()
             }).ToList();
-
             if (tableQuestionIdGroup.Any(x => x.Count > 1))
             {
                 throw new BusinessValidationFailedException(_localizer["ReadingImage_Twice"]);
             }
-
             if (inDto.RowIndex % 1 == 0)
             {
 
@@ -2105,15 +2103,11 @@ namespace IRaCIS.Application.Services
             {
                 isCurrentTaskAdd = isCurrentTaskAddList[0];
             }
-
-
             ReadingTableAnswerRowInfo? rowInfo = await _readingTableAnswerRowInfoRepository.Where(x => x.Id == (inDto.RowId ?? default(Guid))).IgnoreAutoIncludes().FirstOrDefaultAsync();
-
             rowInfo = rowInfo == null ? new ReadingTableAnswerRowInfo() : rowInfo;
 
             //await _readingTableQuestionAnswerRepository.BatchDeleteNoTrackingAsync(x => x.RowId == (inDto.RowId ?? default(Guid)));
             //await _readingTableAnswerRowInfoRepository.BatchDeleteNoTrackingAsync(x => x.Id == (inDto.RowId ?? default(Guid)));
-
             _mapper.Map(inDto, rowInfo);
             rowInfo.Id = inDto.RowId == null ? NewId.NextGuid() : inDto.RowId.Value;
             result.RowId = rowInfo.Id;
@@ -2145,7 +2139,6 @@ namespace IRaCIS.Application.Services
                 await _readingTableQuestionAnswerRepository.AddRangeAsync(answerList);
 
             }
-
             else
             {
                 await _readingTableAnswerRowInfoRepository.UpdateFromDTOAsync(inDto) ;
@@ -2180,7 +2173,6 @@ namespace IRaCIS.Application.Services
 
 
             }
-
             await _readingTableAnswerRowInfoRepository.SaveChangesAsync();
             await this._readingCalculateService.CalculateTask(new CalculateTaskInDto()
             {
@@ -2189,10 +2181,23 @@ namespace IRaCIS.Application.Services
                 ComputationTrigger = ComputationTrigger.Lesion,
             });
 
+            // 保存完了计算疾病进展
+            switch (taskinfo.TrialReadingCriterion.CriterionType)
+            {
+				case CriterionType.Lugano2014:
+                    if (inDto.RowIndex % 1 != 0)
+                    {
+                        await _luganoCalculateService.CalculateTargetLesionStatus(new CalculateTargetLesionStatusInDto()
+                        {
+                            QuestionId = inDto.QuestionId,
+                            VisitTaskId = inDto.VisitTaskId,
+                            RowNumber = inDto.RowIndex
+                        });
+                    }
+                    break;
+			}
 
-
-
-            return result;
+			return result;
         }
 
 
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/Interface/ILuganoCalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/Interface/ILuganoCalculateService.cs
new file mode 100644
index 000000000..6ee6012e7
--- /dev/null
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/Interface/ILuganoCalculateService.cs
@@ -0,0 +1,19 @@
+using IRaCIS.Core.Application.ViewModel;
+using System;
+using System.Collections.Generic;
+using System.Linq;
+using System.Text;
+using System.Threading.Tasks;
+
+namespace IRaCIS.Core.Application.Service.ReadingCalculate.Interface
+{
+	public interface ILuganoCalculateService
+	{
+		/// <summary>
+		/// 计算靶病灶状态
+		/// </summary>
+		/// <param name="inDto"></param>
+		/// <returns></returns>
+		Task CalculateTargetLesionStatus(CalculateTargetLesionStatusInDto inDto);
+	}
+}
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs
index c7d12d6c6..ce4553016 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs
@@ -14,13 +14,15 @@ using System.Reflection.Metadata.Ecma335;
 using System.Linq;
 using NPOI.SS.Formula.Functions;
 using DocumentFormat.OpenXml.Drawing.Charts;
+using IRaCIS.Core.Application.Contracts;
+using IRaCIS.Core.Application.Service.ReadingCalculate.Interface;
 
 namespace IRaCIS.Core.Application.Service.ReadingCalculate
 {
 
     [ApiExplorerSettings(GroupName = "Reading")]
-    public class LuganoCalculateService : BaseService, ICriterionCalculateService
-    {
+    public class LuganoCalculateService : BaseService, ICriterionCalculateService, ILuganoCalculateService
+	{
         private readonly IRepository<ReadingTableQuestionAnswer> _readingTableQuestionAnswerRepository;
         private readonly IRepository<VisitTask> _visitTaskRepository;
         private readonly IRepository<ReadingQuestionCriterionTrial> _readingQuestionCriterionTrialRepository;