diff --git a/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs b/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs
index 24d66c4a8..de6a115ee 100644
--- a/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs
@@ -497,5 +497,68 @@ namespace IRaCIS.Core.Application.Service
 			return ResponseOutput.Ok(true);
 		}
 
+        /// <summary>
+        /// CRC 取消确认
+        /// </summary>
+        /// <param name="inDto"></param>
+        /// <returns></returns>
+        [HttpPost]
+		public async Task<IResponseOutput> CRCCancelConfirmClinical(CRCCancelConfirmClinicalInDto inDto)
+        {
+			var dataList = await this.GetCRCConfirmList(new GetCRCConfirmListInDto()
+			{
+				TrialId = inDto.TrialId
+			});
+
+			var presentData = dataList.Where(x => x.ReadModuleId == inDto.ReadModuleId).First();
+
+            if (dataList.Any(x => x.IsPMConfirm && x.LatestScanDate > presentData.LatestScanDate && x.ReadingSetType == presentData.ReadingSetType))
+            {
+				throw new BusinessValidationFailedException("当前数据并非最后一条确认信息,无法取消！");
+			}
+
+            if(presentData.IsPMConfirm)
+            {
+				throw new BusinessValidationFailedException("PM已确认,无法取消！");
+			}
+
+
+			await _readModuleRepository.UpdatePartialFromQueryAsync(x => presentData.ReadModuleId==x.Id, x => new ReadModule()
+			{
+				IsCRCConfirm = false
+			});
+
+			await _readModuleCriterionFromRepository.BatchDeleteNoTrackingAsync(x=>x.ReadModuleId== presentData.ReadModuleId);
+
+			await _readModuleCriterionFromRepository.SaveChangesAsync();
+
+			return ResponseOutput.Ok(true);
+		}
+
+        /// <summary>
+        /// PM确认临床数据
+        /// </summary>
+        /// <param name="inDto"></param>
+        /// <returns></returns>
+        /// <exception cref="BusinessValidationFailedException"></exception>
+        [HttpPost]
+        public async Task<IResponseOutput> PMConfirmClinical(CRCConfirmClinicalInDto inDto)
+        {
+            var readModuleData = await _readModuleRepository.Where(x => x.Id == inDto.ReadModuleId).FirstNotNullAsync();
+            if (!readModuleData.IsCRCConfirm)
+            {
+				throw new BusinessValidationFailedException("CRC还未确认数据,PM无法确认");
+			}
+
+			await _readModuleRepository.UpdatePartialFromQueryAsync(x => inDto.ReadModuleId == x.Id, x => new ReadModule()
+			{
+				IsPMConfirm = false
+			});
+
+			await _readModuleRepository.SaveChangesAsync();
+
+			return ResponseOutput.Ok(true);
+		}
+
 	}
 }
diff --git a/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs b/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs
index 88523ebfe..2f242db0b 100644
--- a/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs
+++ b/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs
@@ -99,7 +99,14 @@ namespace IRaCIS.Core.Application.Service.Reading.Dto
 		public Guid TrialId { get; set; }
 	}
 
-    public class CRCConfirmClinicalInDto
+    public class CRCCancelConfirmClinicalInDto
+    {
+		public Guid TrialId { get; set; }
+
+		public Guid ReadModuleId { get; set; }
+	}
+
+	public class CRCConfirmClinicalInDto
     {
 		public Guid TrialId { get; set; }