diff --git a/IRaCIS.Core.Application/IRaCIS.Core.Application.xml b/IRaCIS.Core.Application/IRaCIS.Core.Application.xml
index 9484ed445..166aab25c 100644
--- a/IRaCIS.Core.Application/IRaCIS.Core.Application.xml
+++ b/IRaCIS.Core.Application/IRaCIS.Core.Application.xml
@@ -2536,11 +2536,47 @@
             <param name="inDto"></param>
             <returns></returns>
         </member>
+        <member name="M:IRaCIS.Core.Application.Service.ClinicalAnswerService.CRCConfirmClinical(IRaCIS.Core.Application.Service.Reading.Dto.CRCConfirmClinicalInDto)">
+            <summary>
+            CRC 确认临床数据
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ClinicalAnswerService.CRCCancelConfirmClinical(IRaCIS.Core.Application.Service.Reading.Dto.CRCCancelConfirmClinicalInDto)">
+            <summary>
+            CRC 取消确认
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ClinicalAnswerService.PMConfirmClinical(IRaCIS.Core.Application.Service.Reading.Dto.CRCConfirmClinicalInDto)">
+            <summary>
+            PM确认临床数据
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+            <exception cref="T:IRaCIS.Core.Infrastructure.BusinessValidationFailedException"></exception>
+        </member>
         <member name="T:IRaCIS.Core.Application.Service.ClinicalQuestionService">
             <summary>
             临床数据问题
             </summary>	
         </member>
+        <member name="M:IRaCIS.Core.Application.Service.ClinicalQuestionService.GetTrialClinicalQuestionCalculateRelation(IRaCIS.Core.Application.Service.Reading.Dto.GetTrialClinicalQuestionCalculateRelationInDto)">
+            <summary>
+            获取问题计算关系 
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
+        <member name="M:IRaCIS.Core.Application.Service.ClinicalQuestionService.GetClinicalCalculateQuestions(IRaCIS.Core.Application.Service.Reading.Dto.GetClinicalCalculateQuestionsInDto)">
+            <summary>
+            获取计算问题
+            </summary>
+            <param name="inDto"></param>
+            <returns></returns>
+        </member>
         <member name="M:IRaCIS.Core.Application.Service.ClinicalQuestionService.GetSystemClinicalQuestionPreview(IRaCIS.Core.Application.Service.Reading.Dto.GetSystemClinicalQuestionPreviewDto)">
             <summary>
             获取系统临床数据预览
@@ -2682,11 +2718,16 @@
             <param name="inDto"></param>
             <returns></returns>
         </member>
-        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.CRCConfirmFormList.ClinicalDataLevel">
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.CRCClinicalForm.ClinicalDataLevel">
             <summary>
             临床级别
             </summary>
         </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetCRCConfirmListOutDto.SubjectId">
+            <summary>
+            受试者ID
+            </summary>
+        </member>
         <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetCRCConfirmListOutDto.LatestScanDate">
             <summary>
             最晚拍片日期
@@ -2922,6 +2963,46 @@
             是否启用
             </summary>
         </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetTrialClinicalQuestionCalculateRelationInDto.TrialClinicalId">
+            <summary>
+            项目临床数据Id
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetTrialClinicalQuestionCalculateRelationOutDto.QuestionName">
+            <summary>
+            问题名称
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetTrialClinicalQuestionCalculateRelationOutDto.CustomCalculateMark">
+            <summary>
+            自定义计算标记
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetTrialClinicalQuestionCalculateRelationOutDto.ValueType">
+            <summary>
+            数值类型
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetTrialClinicalQuestionCalculateRelationOutDto.Unit">
+            <summary>
+            单位
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetTrialClinicalQuestionCalculateRelationOutDto.CustomUnit">
+            <summary>
+            自定义单位
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetClinicalCalculateQuestionsInDto.TrialClinicalId">
+            <summary>
+            项目临床数据Id
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetClinicalCalculateQuestionsInDto.ClinicalQuestionType">
+            <summary>
+            临床问题类型(分组，单选。)
+            </summary>
+        </member>
         <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.GetSystemClinicalQuestionPreviewDto.SystemClinicalId">
             <summary>
             系统临床数据Id
@@ -2947,6 +3028,11 @@
             子问题
             </summary>
         </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.ClinicalQuestionPreviewDto.RelationQuestions">
+            <summary>
+            关联问题
+            </summary>
+        </member>
         <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.ClinicalQuestionPreviewDto.TableQuestions">
             <summary>
             表格问题
@@ -3067,6 +3153,16 @@
             单位
             </summary>
         </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.ClinicalQuestionBase.CustomCalculateMark">
+            <summary>
+            自定义计算标记
+            </summary>
+        </member>
+        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.ClinicalQuestionBase.CalculateQuestions">
+            <summary>
+            自定义计算问题
+            </summary>
+        </member>
         <member name="T:IRaCIS.Core.Application.Service.Reading.Dto.ClinicalQuestionQueryBase">
             <summary>
             查询临床数据基类
@@ -3097,16 +3193,6 @@
             项目临床数据Id
             </summary>
         </member>
-        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.TrialClinicalQuestionDto.ClinicalCalculateMarkEnum">
-            <summary>
-            自定义计算标记
-            </summary>
-        </member>
-        <member name="P:IRaCIS.Core.Application.Service.Reading.Dto.TrialClinicalQuestionDto.CalculateQuestions">
-            <summary>
-            自定义计算问题
-            </summary>
-        </member>
         <member name="T:IRaCIS.Core.Application.Service.Reading.Dto.SystemClinicalQuestionQuery">
             <summary>
             获取系统临床数据