diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs
index 76b639edf..ced5c5a11 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs
@@ -1247,6 +1247,7 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
                 // 当前访视新病灶数量
                 var thisNewLesionsCount = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewLesionsCount).Select(x => x.Answer).FirstIsNullReturnEmpty().IsNullOrEmptyReturn0();
 
+
                 // 其他访视的BTN
                 var otherBTNStrList =await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId != inDto.VisitTaskId && taskIdList.Contains(x.VisitTaskId) && x.ReadingQuestionTrial.QuestionType == QuestionType.BaseLineLesionsCount).Select(x=>new { 
                 x.VisitTask.VisitTaskNum,
@@ -1254,13 +1255,24 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
                 }).ToListAsync();
 
                 // 最小的BTN 这个时候再转为int 避免查询报错
-                var othenMinBTNCount= otherBTNStrList.Select(x => x.Answer.IsNullOrEmptyReturn0()).Min();
+                var otherMinBTNCount= otherBTNStrList.Select(x => x.Answer.IsNullOrEmptyReturn0()).Min();
+
+
+                // [(V3 - BTN - Min（V2 - BTN、V1 - BTN、BL - BTN）] 小于当0计算
+
+                var btnValue = thisBTN - otherMinBTNCount;
+
+                if (btnValue < 0)
+                {
+                    btnValue = 0;
+                }
 
                 // 历史有PD
                 if (pdTaskList.Count() > 0)
                 {
                     // 当前访视：自治疗后第二个访视点以来持续的新骨变数量 + [(V3 - BTN - Min（V2 - BTN、V1 - BTN、BL - BTN）] + 新病灶 >= 2
-                    if (thisNewBoneLesionsCount + thisBTN - othenMinBTNCount + thisNewLesionsCount >= 2)
+
+                    if (thisNewBoneLesionsCount + btnValue + thisNewLesionsCount >= 2)
                     {
                         result.IsPD = true;
                     }
@@ -1301,9 +1313,16 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
                         // V3与V2的间隔 >= 6周
 
                         // 按上面条件写三个if看着清晰点
-                        if (lastNewLesionsCount + lastBTN - lastTwoBTN >= 2)
+
+                        var lastBtnSubMin = lastBTN - lastTwoBTN;
+                        if (lastBtnSubMin < 0)
                         {
-                            if (thisNewBoneLesionsCount + thisBTN - othenMinBTNCount + thisNewLesionsCount >= 2)
+                            lastBtnSubMin = 0;
+                        }
+
+                        if (lastNewLesionsCount + lastBtnSubMin >= 2)
+                        {
+                            if (thisNewBoneLesionsCount + btnValue + thisNewLesionsCount >= 2)
                             {
                                 if (daysBetween >= 42)
                                 {