diff --git a/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs b/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs
index efa83276c..dd1465c58 100644
--- a/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs
@@ -304,7 +304,12 @@ namespace IRaCIS.Application.Services
             {
                 return ResponseOutput.NotOk("此问题存在子问题,请先删除子问题");
             }
-            await _readingQuestionSystemRepository.DeleteFromQueryAsync(t => t.Id == id);
+
+			if (await _readingQuestionSystemRepository.AnyAsync(x => x.GroupId == id))
+			{
+				return ResponseOutput.NotOk("此分组已被引用,请先删除被引用的问题");
+			}
+			await _readingQuestionSystemRepository.DeleteFromQueryAsync(t => t.Id == id);
             var success = await _readingQuestionSystemRepository.SaveChangesAsync();
             return ResponseOutput.Result(success);
         }
@@ -587,7 +592,12 @@ namespace IRaCIS.Application.Services
             {
                 return ResponseOutput.NotOk("此问题存在子问题,请先删除子问题");
             }
-            await _readingQuestionTrialRepository.DeleteFromQueryAsync(t => t.Id == id);
+
+			if (await _readingQuestionTrialRepository.AnyAsync(x => x.GroupId == id))
+			{
+				return ResponseOutput.NotOk("此分组已被引用,请先删除引用的问题");
+			}
+			await _readingQuestionTrialRepository.DeleteFromQueryAsync(t => t.Id == id);
             var success = await _readingQuestionTrialRepository.SaveChangesAsync();
             return ResponseOutput.Result(success);
         }
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs
index 3d95d93d5..96f7ed5df 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs
@@ -117,7 +117,7 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
             var visitTaskIds = taskInfoList.Select(x => x.VisitTaskId).ToList();
 
             var criterionId = visitTaskInfo.TrialReadingCriterionId;
-            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId).ToListAsync();
+            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId&&x.ShowQuestion!= ShowQuestion.Hide).ToListAsync();
             var tableQuestionList = await _readingTableQuestionTrialRepository.Where(x => x.TrialCriterionId == criterionId).OrderBy(x => x.ShowOrder).ToListAsync();
             var tableAnsweRowInfos = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == indto.VisitTaskId).ProjectTo<TableAnsweRowInfo>(_mapper.ConfigurationProvider).ToListAsync();
 
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs
index 9de54e128..1c12533a1 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/PCWG3CalculateService.cs
@@ -115,7 +115,7 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
             var visitTaskIds = taskInfoList.Select(x => x.VisitTaskId).ToList();
 
             var criterionId = visitTaskInfo.TrialReadingCriterionId;
-            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId)
+            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId && x.ShowQuestion != ShowQuestion.Hide)
                 //.Where(x => x.LesionType != LesionType.BaselineLesions)
                 .Where(x=>x.QuestionType!=QuestionType.TherapeuticEffectEvaluationGroup)
                 .ToListAsync();
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1CalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1CalculateService.cs
index beb743dde..c5fb7d69c 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1CalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1CalculateService.cs
@@ -107,7 +107,7 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
             var visitTaskIds = taskInfoList.Select(x => x.VisitTaskId).ToList();
 
             var criterionId = visitTaskInfo.TrialReadingCriterionId;
-            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId).ToListAsync();
+            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId && x.ShowQuestion != ShowQuestion.Hide).ToListAsync();
             var tableQuestionList = await _readingTableQuestionTrialRepository.Where(x => x.TrialCriterionId == criterionId).OrderBy(x => x.ShowOrder).ToListAsync();
             var tableAnsweRowInfos = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == indto.VisitTaskId).ProjectTo<TableAnsweRowInfo>(_mapper.ConfigurationProvider).ToListAsync();
 
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1_BMCalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1_BMCalculateService.cs
index 06e9262d1..72b331209 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1_BMCalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/RECIST1Point1_BMCalculateService.cs
@@ -107,7 +107,7 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
             var visitTaskIds = taskInfoList.Select(x => x.VisitTaskId).ToList();
 
             var criterionId = visitTaskInfo.TrialReadingCriterionId;
-            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId).ToListAsync();
+            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId && x.ShowQuestion != ShowQuestion.Hide).ToListAsync();
             var tableQuestionList = await _readingTableQuestionTrialRepository.Where(x => x.TrialCriterionId == criterionId).OrderBy(x => x.ShowOrder).ToListAsync();
             var tableAnsweRowInfos = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == indto.VisitTaskId).ProjectTo<TableAnsweRowInfo>(_mapper.ConfigurationProvider).ToListAsync();
 
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/SelfDefineCalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/SelfDefineCalculateService.cs
index 45e7fd709..d6ed8fe62 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/SelfDefineCalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/SelfDefineCalculateService.cs
@@ -105,7 +105,7 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
             var visitTaskIds = taskInfoList.Select(x => x.VisitTaskId).ToList();
 
             var criterionId = visitTaskInfo.TrialReadingCriterionId;
-            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId).ToListAsync();
+            var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId && x.ShowQuestion != ShowQuestion.Hide).ToListAsync();
             var tableQuestionList = await _readingTableQuestionTrialRepository.Where(x => x.TrialCriterionId == criterionId).OrderBy(x => x.ShowOrder).ToListAsync();
 
             var lesionsIndexs = await _readingTableAnswerRowInfoRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).GroupBy(x => new { x.QuestionId }).Select(x => new lesionsIndexDto()
diff --git a/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs b/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs
index acc889d4b..7e875cf48 100644
--- a/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs
+++ b/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs
@@ -247,7 +247,6 @@ namespace IRaCIS.Core.Application
                     var criterionDictionaryList = await _readingCriterionDictionaryRepository.Where(x => x.CriterionId == trialCriterion.ReadingQuestionCriterionSystemId.Value)
                         .Select(x=>new ReadingTrialCriterionDictionary() {
 
-							Id = NewId.NextGuid(),
 					        CriterionId = inDto.TrialReadingCriterionId,
                             CrterionDictionaryGroup=x.CrterionDictionaryGroup,
                             IsBaseLineUse=x.IsBaseLineUse,
@@ -256,8 +255,15 @@ namespace IRaCIS.Core.Application
                             ParentCode=x.ParentCode,
 				       })
                        .ToListAsync();
-                   
-                    await _readingTrialCriterionDictionaryRepository.AddRangeAsync(criterionDictionaryList);
+
+                    criterionDictionaryList.ForEach(x =>
+                    {
+
+                        x.Id = NewId.NextGuid();
+
+                    });
+
+					await _readingTrialCriterionDictionaryRepository.AddRangeAsync(criterionDictionaryList);
 
                     await _trialCriterionDictionaryCode.AddRangeAsync(criterionDictionaryCodeList);
                     #endregion