diff --git a/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs b/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs
index 19b0d7c54..24d66c4a8 100644
--- a/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalAnswerService.cs
@@ -408,56 +408,94 @@ namespace IRaCIS.Core.Application.Service
         [HttpPost]
         public async Task<List<GetCRCConfirmListOutDto>> GetCRCConfirmList(GetCRCConfirmListInDto inDto)
         {
-
-            List<GetCRCConfirmListOutDto> result = await _readModuleRepository.Where(x => x.TrialId == inDto.TrialId)
-                .Select(x => new GetCRCConfirmListOutDto()
-                {
-                    IsCRCConfirm = x.IsCRCConfirm,
-                    LatestScanDate = x.SubjectVisit.LatestScanDate,
-                    ReadingSetType = x.ReadingSetType,
-                    IsPMConfirm = x.IsPMConfirm,
-                    ReadModuleId=x.Id,
-
-                }).OrderBy(x => x.LatestScanDate).ToListAsync();
-
-            var formList = await _clinicalFormRepository.Where(x => x.TrialId == inDto.TrialId)
-                .Where(x=> x.ClinicalDataTrialSet.UploadRole==UploadRole.CRC)
-                .Where(x=> x.ClinicalDataTrialSet.ClinicalDataLevel==ClinicalLevel.ImageRead|| x.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.OncologyRead)
-                .Select(x =>new CRCConfirmFormList
-			{ 
-            CkeckDate=x.CheckDate,
-			ClinicalDataLevel= x.ClinicalDataTrialSet.ClinicalDataLevel,
-
-
-			}).ToListAsync();
-
-            var confirmList = await _readModuleCriterionFromRepository.Where(x => x.TrialId == inDto.TrialId).ToListAsync();
-
+			List<GetCRCConfirmListOutDto> result = await _readModuleRepository.Where(x => x.TrialId == inDto.TrialId)
+				.Select(x => new GetCRCConfirmListOutDto()
+				{
+                    SubjectId= x.SubjectId,
+					IsCRCConfirm = x.IsCRCConfirm,
+					LatestScanDate = x.SubjectVisit.LatestScanDate,
+					ReadingSetType = x.ReadingSetType,
+					IsPMConfirm = x.IsPMConfirm,
+					ReadModuleId = x.Id,
+				}).OrderBy(x => x.LatestScanDate).ToListAsync();
+			var formList = await _clinicalFormRepository.Where(x => x.TrialId == inDto.TrialId)
+				.Where(x => x.ClinicalDataTrialSet.UploadRole == UploadRole.CRC)
+				.Where(x => x.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.ImageRead || x.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.OncologyRead)
+				.Select(x => new CRCClinicalForm
+				{
+					CkeckDate = x.CheckDate,
+					ClinicalDataLevel = x.ClinicalDataTrialSet.ClinicalDataLevel,
+					ClinicalFormId = x.Id,
+				}).ToListAsync();
+			var confirmList = await _readModuleCriterionFromRepository.Where(x => x.TrialId == inDto.TrialId).ToListAsync();
             result.ForEach(x =>
             {
                 if (x.IsCRCConfirm)
                 {
-                    x.FormCount = confirmList.Where(y => y.ReadModuleId == x.ReadModuleId).Count();
-
+                    x.ClinicalFormIdList = confirmList.Where(y => y.ReadModuleId == x.ReadModuleId).Select(y=>y.ClinicalFormId).ToList();
                 }
                 else
                 {
                     if (x.ReadingSetType == ReadingSetType.ImageReading)
                     {
-                        x.FormCount = formList.Where(y => y.ClinicalDataLevel == ClinicalLevel.ImageRead&&y.CkeckDate<=x.LatestScanDate).Count();
-
+                        x.ClinicalFormIdList = formList.Where(y => y.ClinicalDataLevel == ClinicalLevel.ImageRead&&y.CkeckDate<=x.LatestScanDate).Select(y => y.ClinicalFormId).ToList();
                     }
                     else
                     {
-						x.FormCount = formList.Where(y => y.ClinicalDataLevel == ClinicalLevel.OncologyRead&&y.CkeckDate <= x.LatestScanDate).Count();
+						x.ClinicalFormIdList = formList.Where(y => y.ClinicalDataLevel == ClinicalLevel.OncologyRead&&y.CkeckDate <= x.LatestScanDate).Select(y => y.ClinicalFormId).ToList();
 					}
-
 				}
-
             });
             return result;
 		}
 
 
+        /// <summary>
+        /// CRC 确认临床数据
+        /// </summary>
+        /// <param name="inDto"></param>
+        /// <returns></returns>
+        [HttpPost]
+        public async Task<IResponseOutput> CRCConfirmClinical(CRCConfirmClinicalInDto inDto)
+        {
+            var dataList =await this.GetCRCConfirmList(new GetCRCConfirmListInDto()
+            {
+                TrialId = inDto.TrialId
+            });
+
+            var presentData = dataList.Where(x => x.ReadModuleId == inDto.ReadModuleId).First();
+            var confirmlist=  dataList.Where(x =>(x.LatestScanDate < presentData.LatestScanDate && x.ReadingSetType == presentData.ReadingSetType) 
+            || x.ReadModuleId == presentData.ReadModuleId).Where(x => !x.IsCRCConfirm).ToList();
+
+            List<ReadModuleCriterionFrom> needAddList = new List<ReadModuleCriterionFrom>()
+            {
+
+            };
+            confirmlist.ForEach(x =>
+            {
+                x.ClinicalFormIdList.ForEach(y =>
+                {
+                    needAddList.Add(new ReadModuleCriterionFrom()
+                    {
+                        ClinicalFormId = y,
+                        ReadModuleId = x.ReadModuleId,
+                        SubjectId = x.SubjectId,
+                        TrialId = inDto.TrialId,
+                    });
+				});
+            });
+
+            var readModuleIds = confirmlist.Select(x => x.ReadModuleId).ToList();
+
+            await _readModuleRepository.UpdatePartialFromQueryAsync(x => readModuleIds.Contains(x.Id),x=>new ReadModule() { 
+            IsCRCConfirm=true
+            });
+            await _readModuleCriterionFromRepository.AddRangeAsync(needAddList);
+
+            await _readModuleCriterionFromRepository.SaveChangesAsync();
+
+			return ResponseOutput.Ok(true);
+		}
+
 	}
 }
diff --git a/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs b/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs
index 081775f70..526d6253c 100644
--- a/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs
+++ b/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalAnswerDto.cs
@@ -99,10 +99,20 @@ namespace IRaCIS.Core.Application.Service.Reading.Dto
 		public Guid TrialId { get; set; }
 	}
 
-    public class CRCConfirmFormList
+    public class CRCConfirmClinicalInDto
+    {
+		public Guid TrialId { get; set; }
+
+		public Guid ReadModuleId { get; set; }
+	}
+
+
+	public class CRCClinicalForm
     {
 		public DateTime? CkeckDate { get; set; }
 
+        public Guid ClinicalFormId { get; set; }
+
 		/// <summary>
 		/// 临床级别
 		/// </summary>
@@ -125,7 +135,16 @@ namespace IRaCIS.Core.Application.Service.Reading.Dto
 		/// </summary>
 		public DateTime? LatestScanDate { get; set; }
 
-        public int FormCount { get; set; }
+
+        public List<Guid> ClinicalFormIdList { get; set; }
+
+		public int FormCount
+		{
+			get
+			{
+				return this.ClinicalFormIdList.Count();
+			}
+		}
 	}
 
 	public class SubmitClinicalFormInDto
diff --git a/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalQuestionDto.cs b/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalQuestionDto.cs
index af441a447..9474d06c5 100644
--- a/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalQuestionDto.cs
+++ b/IRaCIS.Core.Application/Service/Reading/Dto/ClinicalQuestionDto.cs
@@ -1,6 +1,8 @@
 using IRaCIS.Core.Domain.Share;
+using Newtonsoft.Json;
 using System;
 using System.Collections.Generic;
+using System.ComponentModel.DataAnnotations.Schema;
 using System.Linq;
 using System.Text;
 using System.Threading.Tasks;
@@ -178,7 +180,37 @@ namespace IRaCIS.Core.Application.Service.Reading.Dto
         /// 单位
         /// </summary>
         public string Unit { get; set; } = string.Empty;
-    }
+
+		/// <summary>
+		/// 自定义计算标记
+		/// </summary>
+		public ClinicalCalculateMark? CustomCalculateMark { get; set; }
+
+		/// <summary>
+		/// 自定义计算问题
+		/// </summary>
+		public string CalculateQuestions { get; set; } = "[]";
+
+		[NotMapped]
+		public List<CalculateInfo> CalculateQuestionList
+		{
+			get
+			{
+
+				try
+				{
+					var result = JsonConvert.DeserializeObject<List<CalculateInfo>>(this.CalculateQuestions);
+					return result == null ? new List<CalculateInfo>() : result;
+				}
+				catch (Exception)
+				{
+
+					return new List<CalculateInfo>();
+				}
+
+			}
+		}
+	}
 
     /// <summary>
     /// 查询临床数据基类
@@ -218,16 +250,6 @@ namespace IRaCIS.Core.Application.Service.Reading.Dto
         /// 项目临床数据Id
         /// </summary>
         public Guid TrialClinicalId { get; set; }
-
-        /// <summary>
-        /// 自定义计算标记
-        /// </summary>
-        public ClinicalCalculateMark? ClinicalCalculateMarkEnum { get; set; }
-
-        /// <summary>
-        /// 自定义计算问题
-        /// </summary>
-        public string CalculateQuestions { get; set; } = "[]";
     }
 
     /// <summary>
diff --git a/IRaCIS.Core.Domain/Reading/ClinicalQuestion/SystemClinicalQuestion.cs b/IRaCIS.Core.Domain/Reading/ClinicalQuestion/SystemClinicalQuestion.cs
index dac8fb262..ee996922a 100644
--- a/IRaCIS.Core.Domain/Reading/ClinicalQuestion/SystemClinicalQuestion.cs
+++ b/IRaCIS.Core.Domain/Reading/ClinicalQuestion/SystemClinicalQuestion.cs
@@ -126,7 +126,37 @@ namespace IRaCIS.Core.Domain.Models
         /// 单位
         /// </summary>
         public string Unit { get; set; } = string.Empty;
-    }
+
+		/// <summary>
+		/// 自定义计算标记
+		/// </summary>
+		public ClinicalCalculateMark? CustomCalculateMark { get; set; }
+
+		/// <summary>
+		/// 自定义计算问题
+		/// </summary>
+		public string CalculateQuestions { get; set; } = "[]";
+
+		[NotMapped]
+		public List<CalculateInfo> CalculateQuestionList
+		{
+			get
+			{
+
+				try
+				{
+					var result = JsonConvert.DeserializeObject<List<CalculateInfo>>(this.CalculateQuestions);
+					return result == null ? new List<CalculateInfo>() : result;
+				}
+				catch (Exception)
+				{
+
+					return new List<CalculateInfo>();
+				}
+
+			}
+		}
+	}
 
 
 }
diff --git a/IRaCIS.Core.Domain/Reading/ClinicalQuestion/TrialClinicalQuestion.cs b/IRaCIS.Core.Domain/Reading/ClinicalQuestion/TrialClinicalQuestion.cs
index 97ef17e9e..f741b2f93 100644
--- a/IRaCIS.Core.Domain/Reading/ClinicalQuestion/TrialClinicalQuestion.cs
+++ b/IRaCIS.Core.Domain/Reading/ClinicalQuestion/TrialClinicalQuestion.cs
@@ -8,6 +8,7 @@ using IRaCIS.Core.Domain.Share;
 using System.ComponentModel.DataAnnotations;
 using System.ComponentModel.DataAnnotations.Schema;
 using IRaCIS.Core.Domain.Models;
+using System.Collections.Generic;
 
 namespace IRaCIS.Core.Domain.Models
 {
@@ -125,17 +126,37 @@ namespace IRaCIS.Core.Domain.Models
         /// <summary>
         /// 自定义计算标记
         /// </summary>
-        public  ClinicalCalculateMark? ClinicalCalculateMarkEnum { get; set; }
+        public  ClinicalCalculateMark? CustomCalculateMark { get; set; }
 
         /// <summary>
         /// 自定义计算问题
         /// </summary>
         public string CalculateQuestions { get; set; } = "[]";
 
-        /// <summary>
-        /// 小数点位数
-        /// </summary>
-        public int? DigitPlaces { get; set; }
+		[NotMapped]
+		public List<CalculateInfo> CalculateQuestionList
+		{
+			get
+			{
+
+				try
+				{
+					var result = JsonConvert.DeserializeObject<List<CalculateInfo>>(this.CalculateQuestions);
+					return result == null ? new List<CalculateInfo>() : result;
+				}
+				catch (Exception)
+				{
+
+					return new List<CalculateInfo>();
+				}
+
+			}
+		}
+
+		/// <summary>
+		/// 小数点位数
+		/// </summary>
+		public int? DigitPlaces { get; set; }
 
         /// <summary>
         /// 单位