diff --git a/IRaCIS.Core.Application/Resources/en-US.json b/IRaCIS.Core.Application/Resources/en-US.json
index 4cb655ec8..70d24362f 100644
--- a/IRaCIS.Core.Application/Resources/en-US.json
+++ b/IRaCIS.Core.Application/Resources/en-US.json
@@ -11,6 +11,7 @@
   "ReadingImage_CantSplit": "The current read is a baseline read, and lesion split is not allowed.",
   "ReadingImage_BeSigned": "The current read has already been signed off. Please do not submit it again.",
   "ReadingImage_Beinvalid": "The current read has already been invalidated, and reading is not allowed anymore.",
+  "ReadingImage_PresenceReview": "The current subject has a review request that has not been processed and is not allowed to operate",
   "ReadingImage_NotaTask": "The coalesced lesions are not from the same timepoint. ",
   "ReadingImage_DeleteError": "Other lesions have split from or coalesced into the current lesion. Deletion failed.",
   "ReadingImage_Idnotcorrespond": "Failed to add the lesion mark. The Instance ID and Series ID of the image do not match.",
@@ -52,8 +53,6 @@
   "Repository_DeleteError": "Deleted data does not exist in the database.",
 
 
-
-
   // ------------------------------------------------------------Allocation--------------------------------------------------------------------
   //TaskAllocationRuleService
   "TaskAllocation_DoctorIdNotFound": "Error, the doctor is account Id was not found in the enrollment table.",
diff --git a/IRaCIS.Core.Application/Resources/zh-CN.json b/IRaCIS.Core.Application/Resources/zh-CN.json
index c413f4073..c148776bb 100644
--- a/IRaCIS.Core.Application/Resources/zh-CN.json
+++ b/IRaCIS.Core.Application/Resources/zh-CN.json
@@ -10,6 +10,7 @@
   "ReadingImage_CantSplit": "当前任务是基线任务,不能执行分裂病灶的操作。",
   "ReadingImage_BeSigned": "当前任务已经签名，请勿重复提交。",
   "ReadingImage_Beinvalid": "当前任务已失效，不能执行阅片。",
+  "ReadingImage_PresenceReview": "当前受试者存在重阅申请还未处理,不允许操作",
   "ReadingImage_NotaTask": "合并的病灶并非同一个访视任务",
   "ReadingImage_DeleteError": "当前病灶分裂出其他病灶或者其他病灶合并到了当前病灶,删除失败。",
   "ReadingImage_Idnotcorrespond": "病灶标记添加失败，影像的Instance ID和Series ID不对应。",
@@ -51,7 +52,6 @@
   "Repository_DeleteError": "删除的数据在数据库不存在。",
 
 
-
   // ------------------------------------------------------------Allocation--------------------------------------------------------------------
   //TaskAllocationRuleService
   "TaskAllocation_DoctorIdNotFound": "错误，未在入组表中找到该医生的账号Id",
diff --git a/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs b/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs
index 41896725d..0104ae196 100644
--- a/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ReadingImageTask/ReadingImageTaskService.cs
@@ -569,6 +569,8 @@ namespace IRaCIS.Application.Services
         /// <exception cref="BusinessValidationFailedException"></exception>
         private async Task VerifyTaskIsSign(Guid visitTaskid)
         {
+            var taskInfo = await _visitTaskRepository.Where(x => x.Id == visitTaskid).FirstNotNullAsync();
+
             if (await _visitTaskRepository.AnyAsync(x => x.Id == visitTaskid && x.ReadingTaskState == ReadingTaskState.HaveSigned))
             {
                 throw new BusinessValidationFailedException(_localizer["ReadingImage_BeSigned"]);
@@ -579,6 +581,17 @@ namespace IRaCIS.Application.Services
             {
                 throw new BusinessValidationFailedException(_localizer["ReadingImage_Beinvalid"]);
             }
+
+            if (await _visitTaskRepository.AnyAsync(x => x.TrialReadingCriterionId == taskInfo.TrialReadingCriterionId
+            &&x.IsAnalysisCreate&&taskInfo.IsAnalysisCreate
+            &&x.SubjectId== taskInfo.SubjectId&&x.TaskState==TaskState.Effect&&
+            ((x.ReReadingApplyState==ReReadingApplyState.DocotorHaveApplyed && x.DoctorUserId == taskInfo.DoctorUserId)|| x.ReReadingApplyState == ReReadingApplyState.TrialGroupHaveApplyed)
+
+            ))
+            {
+                throw new BusinessValidationFailedException(_localizer["ReadingImage_PresenceReview"]);
+            }
+
         }
 
 
@@ -2063,7 +2076,7 @@ namespace IRaCIS.Application.Services
 
             var isConvertedTask = await _visitTaskRepository.Where(x => x.Id == inDto.VisitTaskId).Select(x=>x.IsConvertedTask).FirstNotNullAsync();
 
-            if (await _readingTableAnswerRowInfoRepository.AnyAsync(x => x.ReadingQuestionTrial.LesionType == LesionType.NewLesions && x.VisitTaskId == inDto.VisitTaskId))
+            if (isConvertedTask&&(await _readingTableAnswerRowInfoRepository.AnyAsync(x => x.ReadingQuestionTrial.LesionType == LesionType.NewLesions && x.VisitTaskId == inDto.VisitTaskId)))
             {
                 throw new BusinessValidationFailedException(_localizer["ReadingImage_NotNewFocus"]);
             }
diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs
index 7f3579e0d..0b6782622 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/IRECIST1Point1CalculateService.cs
@@ -1574,7 +1574,11 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
         #endregion
 
 
-
+        /// <summary>
+        /// 获取新靶病灶评估
+        /// </summary>
+        /// <param name="inDto"></param>
+        /// <returns></returns>
         public async Task<string> GetNewTargetLesionEvaluate(ReadingCalculateDto inDto)
         {
             var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
diff --git a/后端提示语.xlsx b/后端提示语.xlsx
index ccb26eee1..12a5f5a5c 100644
Binary files a/后端提示语.xlsx and b/后端提示语.xlsx differ