diff --git a/IRaCIS.Core.Application/Service/Reading/ReadingMedicineQuestionService.cs b/IRaCIS.Core.Application/Service/Reading/ReadingMedicineQuestionService.cs
index 0eb3e688f..2fca14b75 100644
--- a/IRaCIS.Core.Application/Service/Reading/ReadingMedicineQuestionService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ReadingMedicineQuestionService.cs
@@ -52,12 +52,20 @@ namespace IRaCIS.Core.Application.Service
 		/// <summary>
 		/// 新增或修改系统医学审核问题
 		/// </summary>
-		/// <param name="addOrEditReadingMedicineSystemQuestion"></param>
+		/// <param name="inDto"></param>
 		/// <returns></returns>
 		[HttpPost]
-		public async Task<IResponseOutput> AddOrUpdateReadingMedicineSystemQuestion(ReadingMedicineSystemQuestionAddOrEdit addOrEditReadingMedicineSystemQuestion)
+		public async Task<IResponseOutput> AddOrUpdateReadingMedicineSystemQuestion(ReadingMedicineSystemQuestionAddOrEdit inDto)
 		{
-			var entity = await _readingMedicineSystemQuestionRepository.InsertOrUpdateAsync(addOrEditReadingMedicineSystemQuestion);
+			var existsQuery = _readingMedicineSystemQuestionRepository
+			   .WhereIf(inDto.Id != null, x => x.Id != inDto.Id)
+			   .Where(x => x.QuestionName == inDto.QuestionName ||x.ShowOrder == inDto.ShowOrder);
+
+			if (await existsQuery.AnyAsync())
+			{
+				return ResponseOutput.NotOk("当前问题名称或序号存在重复");
+			}
+			var entity = await _readingMedicineSystemQuestionRepository.InsertOrUpdateAsync(inDto);
 			await _readingMedicineSystemQuestionRepository.SaveChangesAsync();
 			return ResponseOutput.Ok(entity.Id.ToString());
 		}
@@ -116,7 +124,7 @@ namespace IRaCIS.Core.Application.Service
 		public async Task<List<GetMedicineQuestionPreviewOutDto>> GetMedicineQuestionPreview(GetMedicineQuestionPreviewInDto inDto)
 		{
 			var trialQuestionList = await _readingMedicineTrialQuestionRepository.Where(x=>x.TrialId==inDto.TrialId)
-				 .ProjectTo<GetMedicineQuestionPreviewOutDto>(_mapper.ConfigurationProvider).ToListAsync();
+				 .ProjectTo<GetMedicineQuestionPreviewOutDto>(_mapper.ConfigurationProvider).OrderBy(x=>x.ShowOrder).ToListAsync();
 		
 			List<GetMedicineQuestionPreviewOutDto> readingQuestionList = trialQuestionList.Where(x => x.ParentId == null).ToList();
 			readingQuestionList.ForEach(x =>
@@ -142,12 +150,20 @@ namespace IRaCIS.Core.Application.Service
 		/// <summary>
 		/// 新增或修改项目医学审核问题
 		/// </summary>
-		/// <param name="addOrEditReadingMedicineTrialQuestion"></param>
+		/// <param name="inDto"></param>
 		/// <returns></returns>
 		[HttpPost]
-		public async  Task<IResponseOutput> AddOrUpdateReadingMedicineTrialQuestion(ReadingMedicineTrialQuestionAddOrEdit addOrEditReadingMedicineTrialQuestion)
+		public async  Task<IResponseOutput> AddOrUpdateReadingMedicineTrialQuestion(ReadingMedicineTrialQuestionAddOrEdit inDto)
 		{
-			var entity = await _readingMedicineTrialQuestionRepository.InsertOrUpdateAsync(addOrEditReadingMedicineTrialQuestion);
+			var existsQuery = _readingMedicineSystemQuestionRepository
+		   .WhereIf(inDto.Id != null, x => x.Id != inDto.Id)
+		   .Where(x => x.QuestionName == inDto.QuestionName || x.ShowOrder == inDto.ShowOrder);
+
+			if (await existsQuery.AnyAsync())
+			{
+				return ResponseOutput.NotOk("当前问题名称或序号存在重复");
+			}
+			var entity = await _readingMedicineTrialQuestionRepository.InsertOrUpdateAsync(inDto);
 			await _readingMedicineTrialQuestionRepository.SaveChangesAsync();
 			return ResponseOutput.Ok(entity.Id.ToString());