diff --git a/IRaCIS.Core.Application/Service/Document/EmailSendService.cs b/IRaCIS.Core.Application/Service/Document/EmailSendService.cs
index 3ba1934e5..20295ce6d 100644
--- a/IRaCIS.Core.Application/Service/Document/EmailSendService.cs
+++ b/IRaCIS.Core.Application/Service/Document/EmailSendService.cs
@@ -380,7 +380,7 @@ namespace IRaCIS.Core.Application.Service
                    .ToList();
 
                 //收件人 有CRC  CRA  ， CRC  CRA的账户要按照中心发送
-                if (siteId == null && toUserTypeEnumList.Any(t => t == UserTypeEnum.ClinicalResearchCoordinator || t == UserTypeEnum.CRA))
+                if (siteId == null && toUserTypeEnumList.Any(t => t == UserTypeEnum.ClinicalResearchCoordinator || t == UserTypeEnum.CRA) && onlyToUserId == null)
                 {
                     throw new BusinessValidationFailedException("当前场景收件人包含CRC CRA,但是没有siteId,请联系后端开发");
                 }