diff --git a/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs b/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs
index 8c99a7088..44f0b2173 100644
--- a/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ReadingCriterion/ReadingQuestionService.cs
@@ -36,6 +36,7 @@ namespace IRaCIS.Core.Application.Service
         IRepository<ReadingTaskQuestionAnswer> _readingTaskQuestionAnswer,
         IRepository<PreviousPDF> _previousPDFRepository,
         IRepository<ReadingQuestionVisitJudgeRule> _readingQuestionVisitJudgeRuleRepository,
+        IRepository<VisitStage> _visitStageRepository,
         IMapper _mapper, IUserInfo _userInfo, IStringLocalizer _localizer) : BaseService, IReadingQuestionService
 
     {
@@ -713,9 +714,61 @@ namespace IRaCIS.Core.Application.Service
             }
 
             var entity = await _readingQuestionTrialRepository.InsertOrUpdateAsync(indto, true);
+            await AddNAJudgeRule(entity);
             return ResponseOutput.Ok(entity.Id.ToString());
         }
 
+        /// <summary>
+        /// 添加问题的不适用规则
+        /// </summary>
+        /// <returns></returns>
+        private async Task AddNAJudgeRule(ReadingQuestionTrial entity)
+        {
+            List<decimal> visitNums = new List<decimal>();
+            if (entity.IsJudgeQuestion)
+            {
+                var visitStageNums = await _visitStageRepository
+               .Where(x => x.TrialId == entity.TrialId)
+               .Select(x => x.VisitNum)
+               .Distinct()
+               .ToListAsync();
+
+                switch (entity.LimitShow)
+                {
+                    case LimitShow.BaseLineShow:
+                        visitNums = visitStageNums.Where(x => x > 0).ToList();
+                        visitNums.Add(-1);
+                        break;
+                    case LimitShow.FollowShow:
+                        visitNums.Add(0);
+                        break;
+                    case LimitShow.ExcludeSomeVisits:
+                        visitNums = entity.ExcludeShowVisitList;
+                        break;
+                }
+            }
+
+            if (visitNums.Count==0)
+            {
+                return;
+            }
+
+
+            await _readingQuestionVisitJudgeRuleRepository.BatchDeleteNoTrackingAsync(x =>
+                x.ReadingQuestionId == entity.Id && visitNums.Contains(x.VisitNum));
+
+            var rules = visitNums.Select(visitNum => new ReadingQuestionVisitJudgeRule
+            {
+                Id = NewId.NextGuid(),
+                ReadingQuestionId = entity.Id,
+                VisitNum = visitNum,
+                JudgeType = JudgeTypeEnum.None,
+            }).ToList();
+
+            await _readingQuestionVisitJudgeRuleRepository.AddRangeAsync(rules);
+            await _readingQuestionVisitJudgeRuleRepository.SaveChangesAsync();
+        }
+
         /// <summary>
         /// 获取项目问题（项目）
         /// </summary>
diff --git a/IRaCIS.Core.Domain/Reading/ReadingCriterionQuestion/ReadingQuestionVisitJudgeRule.cs b/IRaCIS.Core.Domain/Reading/ReadingCriterionQuestion/ReadingQuestionVisitJudgeRule.cs
index 67dcf892d..e44d8c6b1 100644
--- a/IRaCIS.Core.Domain/Reading/ReadingCriterionQuestion/ReadingQuestionVisitJudgeRule.cs
+++ b/IRaCIS.Core.Domain/Reading/ReadingCriterionQuestion/ReadingQuestionVisitJudgeRule.cs
@@ -21,7 +21,7 @@ public class ReadingQuestionVisitJudgeRule : BaseAddAuditEntity
     public Guid ReadingQuestionId { get; set; }
 
     /// <summary>
-    /// 访视Num
+    /// 访视Num (计划外是-1)
     /// </summary>
     public decimal VisitNum { get; set; }