diff --git a/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs b/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs
index 9de580fbe..d3ed2678d 100644
--- a/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs
+++ b/IRaCIS.Core.Application/Service/ReadingCalculate/LuganoCalculateService.cs
@@ -2414,10 +2414,13 @@ namespace IRaCIS.Core.Application.Service.ReadingCalculate
             {
                 result = TargetAssessment.PD;
             }
-            //在排除PD后，有任一靶病灶为NE状态
-            else if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.UnableEvaluate)))
+            //当前访视没有任何一个状态为“疾病进展”的靶病灶；
+            //当前访视存在至少一个状态为“不可评估”的靶病灶。
+            else if (
+                !tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.DiseaseProgression))&&
+                tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.UnableEvaluate)))
             {
-                result = TargetAssessment.PD;
+                result = TargetAssessment.NE;
             }
             //1、基线非淋巴结靶病灶不存在，或者当前访视非淋巴结靶病灶全部消失；
             //并且  2.当前访视淋巴结靶病灶的状态全部变为“消失”。