diff --git a/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs b/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs
index 38bc122f7..913b5c4fd 100644
--- a/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs
+++ b/IRaCIS.Core.Application/Service/TrialSiteUser/TrialConfigService.cs
@@ -871,12 +871,18 @@ namespace IRaCIS.Core.Application
             {
                 var trialConfirmTime = _trialRepository.Where(t => t.Id == signConfirmDTO.TrialId).Select(t => t.QCQuestionConfirmedTime).FirstOrDefault();
 
-                //重复二次复核签名
-                await _subjectVisitRepository.BatchUpdateNoTrackingAsync(t => t.TrialId == signConfirmDTO.TrialId && t.AuditState == AuditStateEnum.QCPassed 
-                && !t.TrialQCQuestionAnswerList.Any(t => t.SecondReviewTime == trialConfirmTime), u => new SubjectVisit() { SecondReviewState = SecondReviewState.WaitAudit });
+                if (trialConfirmTime != null)
+                {
+                    //删除复审中间临时数据
+                    await _qcQuestionAnswerRepository.BatchDeleteNoTrackingAsync(t => t.SubjectVisit.TrialId == signConfirmDTO.TrialId && t.SubjectVisit.SecondReviewState != SecondReviewState.AuditPassed && t.CurrentQCEnum == CurrentQC.SecondReview);
+
+                    //重复二次复核签名
+                    await _subjectVisitRepository.BatchUpdateNoTrackingAsync(t => t.TrialId == signConfirmDTO.TrialId && t.AuditState == AuditStateEnum.QCPassed
+                    && !t.TrialQCQuestionAnswerList.Any(t => t.SecondReviewTime == trialConfirmTime), u => new SubjectVisit() { SecondReviewState = SecondReviewState.WaitAudit });
+
+                   
+                }
 
-                //删除复审中间临时数据
-                await _qcQuestionAnswerRepository.BatchDeleteNoTrackingAsync(t => t.SubjectVisit.TrialId == signConfirmDTO.TrialId && t.SubjectVisit.SecondReviewState != SecondReviewState.AuditPassed && t.CurrentQCEnum == CurrentQC.SecondReview);
             }
             else if (signConfirmDTO.SignCode == ((int)SignEnum.TrialQCQuestionConfirm).ToString())
             {