diff --git a/IRaCIS.Core.Application/Service/Reading/ReadingPeriod/ReadModuleService.cs b/IRaCIS.Core.Application/Service/Reading/ReadingPeriod/ReadModuleService.cs
index e5dff07f2..959e29a84 100644
--- a/IRaCIS.Core.Application/Service/Reading/ReadingPeriod/ReadModuleService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ReadingPeriod/ReadModuleService.cs
@@ -25,6 +25,7 @@ namespace IRaCIS.Application.Services
         private readonly IRepository<Trial> _trialRepository;
         private readonly IVisitTaskHelpeService _visitTaskHelpeService;
         private readonly IRepository<VisitTask> _visitTaskRepository;
+        private readonly IRepository<ReadModuleCriterionFrom> _readModuleCriterionFromRepository;
         private readonly IRepository<ClinicalDataTrialSet> _clinicalDataTrialSetRepository;
         private readonly IRepository<ReadModuleView> _readModuleViewRepository;
         private readonly IRepository<ReadingQuestionCriterionTrial> _readingQuestionCriterionTrialRepository;
@@ -41,6 +42,7 @@ namespace IRaCIS.Application.Services
             IRepository<Trial> trialRepository,
             IVisitTaskHelpeService visitTaskHelpeService,
              IRepository<VisitTask> visitTaskRepository,
+                IRepository<ReadModuleCriterionFrom> readModuleCriterionFromRepository,
             IRepository<ClinicalDataTrialSet> clinicalDataTrialSetRepository,
             IRepository<ReadModuleView> readModuleViewRepository,
             IRepository<ReadingQuestionCriterionTrial> readingQuestionCriterionTrialRepository,
@@ -57,6 +59,7 @@ namespace IRaCIS.Application.Services
             this._trialRepository = trialRepository;
             this._visitTaskHelpeService = visitTaskHelpeService;
             this._visitTaskRepository = visitTaskRepository;
+            this._readModuleCriterionFromRepository = readModuleCriterionFromRepository;
             this._clinicalDataTrialSetRepository = clinicalDataTrialSetRepository;
             this._readModuleViewRepository = readModuleViewRepository;
             this._readingQuestionCriterionTrialRepository = readingQuestionCriterionTrialRepository;
@@ -480,6 +483,14 @@ namespace IRaCIS.Application.Services
                 return ResponseOutput.NotOk(_localizer["ReadModule_SignedDataCannotDelete"]);
             }
 
+            await _readModuleCriterionFromRepository.BatchDeleteNoTrackingAsync(x => x.ReadModuleId == readModuleId);
+
+            if (await _readModuleCriterionFromRepository.AnyAsync(x => x.ReadModuleId == readModuleId))
+            {
+                //---CRC已经确认临床数据 不允许删除
+                return ResponseOutput.NotOk(_localizer["ReadModule_CRCConfirmClinicalData"]);
+            }
+
             //增加标准
             if (readModule.ModuleType==ModuleTypeEnum.Global&&(await _readModuleRepository.AnyAsync(x=>x.ModuleType==ModuleTypeEnum.Oncology&&x.SubjectVisitId== readModule.SubjectVisitId && x.TrialReadingCriterionId==readModule.TrialReadingCriterionId)))
             {
@@ -499,6 +510,7 @@ namespace IRaCIS.Application.Services
                 TaskState = TaskState.Adbandon
             });
 
+           
 
             await _readModuleRepository.UpdatePartialFromQueryAsync(t => t.Id == readModuleId, x => new ReadModule()
             {