diff --git a/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalQuestionService.cs b/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalQuestionService.cs
index 95220eb33..a7110f446 100644
--- a/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalQuestionService.cs
+++ b/IRaCIS.Core.Application/Service/Reading/ClinicalData/ClinicalQuestionService.cs
@@ -238,6 +238,11 @@ namespace IRaCIS.Core.Application.Service
                 return ResponseOutput.NotOk("问题序号存在重复！");
             }
 
+            if (await _trialClinicalQuestionRepository.AnyAsync(x => x.TrialClinicalId == inDto.TrialClinicalId && x.Id != inDto.Id && x.IsCheckDate == inDto.IsCheckDate&&inDto.IsCheckDate))
+            {
+                return ResponseOutput.NotOk("已经添加过类型为检查日期的问题！");
+            }
+
             var entity = await _trialClinicalQuestionRepository.InsertOrUpdateAsync(inDto, true);
             return ResponseOutput.Ok(entity.Id.ToString());
 
@@ -325,6 +330,10 @@ namespace IRaCIS.Core.Application.Service
             {
                 return ResponseOutput.NotOk("问题序号存在重复！");
             }
+            if (await _systemClinicalQuestionRepository.AnyAsync(x => x.SystemClinicalId == inDto.SystemClinicalId && x.Id != inDto.Id && x.IsCheckDate == inDto.IsCheckDate && inDto.IsCheckDate))
+            {
+                return ResponseOutput.NotOk("已经添加过类型为检查日期的问题！");
+            }
             var entity = await _systemClinicalQuestionRepository.InsertOrUpdateAsync(inDto, true);
             return ResponseOutput.Ok(entity.Id.ToString());