using IRaCIS.Core.Application.Service.Reading.Dto;
using IRaCIS.Core.Application.ViewModel;
using IRaCIS.Core.Domain.Share;
using IRaCIS.Core.Infra.EFCore.Common;
using IRaCIS.Core.Infrastructure;
using MassTransit;
using Microsoft.AspNetCore.Mvc;
using Microsoft.Extensions.Logging;
using System.Text;
namespace IRaCIS.Core.Application.Service.ReadingCalculate
{
[ApiExplorerSettings(GroupName = "Reading")]
public class IRECIST1Point1CalculateService(IRepository<ReadingTableQuestionAnswer> _readingTableQuestionAnswerRepository,
IRepository<VisitTask> _visitTaskRepository,
IRepository<ReadingQuestionCriterionTrial> _readingQuestionCriterionTrialRepository,
IRepository<ReadingTableQuestionTrial> _readingTableQuestionTrialRepository,
IRepository<ReadingTableAnswerRowInfo> _readingTableAnswerRowInfoRepository,
IRepository<ReadingQuestionTrial> _readingQuestionTrialRepository,
IRepository<OrganInfo> _organInfoRepository,
IRepository<ReadingGlobalTaskInfo> _readingGlobalTaskInfoRepository,
IRepository<SubjectVisit> _subjectVisitRepository,
IRepository<TumorAssessment_IRECIST1Point1> _tumorAssessmentRepository,
IGeneralCalculateService _generalCalculateService,
IRepository<ReadingTaskQuestionAnswer> _readingTaskQuestionAnswerRepository,
ILogger<IRECIST1Point1CalculateService> _logger, IMapper _mapper, IUserInfo _userInfo, IStringLocalizer _localizer) : BaseService, ICriterionCalculateService
{
/// <summary>
/// 获取阅片的计算数据
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<object> GetReadingCalculationData(GetReadingCalculationDataInDto inDto)
{
return new
{
};
}
#region 临时对象 单个请求的生命周期 避免重复查询数据库
private List<VisitTaskAnswerInfo> visitTaskAnswerList;
/// <summary>
/// 获取Sod的值
/// </summary>
private decimal? sODData;
/// <summary>
/// 获取iSod的值
/// </summary>
private decimal? iSODData;
private string nAString = "NA";
/// <summary>
/// 上一次访视Id
/// </summary>
public Guid? lastVisitTaskId;
/// <summary>
/// 首次转变的任务ID
/// </summary>
public Guid? firstChangeTaskId;
/// <summary>
/// 触发任务list
/// </summary>
public List<TirggerTaskInfo>? compareTaskList = null;
#endregion
#region 删除病灶获取起始病灶序号
/// <summary>
/// 删除病灶获取起始病灶序号（RECIST1Point1 固定是1）
/// </summary>
/// <returns></returns>
public async Task<int> GetDeleteLesionStatrIndex(DeleteReadingRowAnswerInDto inDto)
{
return 1;
}
#endregion
#region 获取阅片报告
/// <summary>
/// 获取阅片报告
/// </summary>
/// <param name="indto"></param>
/// <returns></returns>
[HttpPost]
public async Task<GetReadingReportEvaluationOutDto> GetReadingReportEvaluation(GetReadingReportEvaluationInDto indto)
{
GetReadingReportEvaluationOutDto result = new GetReadingReportEvaluationOutDto();
var isConvertTask = await _visitTaskRepository.Where(x => x.Id == indto.VisitTaskId).Select(x => x.IsConvertedTask).FirstNotNullAsync();
var visitTaskInfo = await _visitTaskRepository.Where(x => x.Id == indto.VisitTaskId).FirstNotNullAsync();
result.CalculateResult = await this.GetReportVerify(new GetReportVerifyInDto()
{
VisitTaskId = indto.VisitTaskId,
IsConvertTask = isConvertTask,
BeforeConvertedTaskId = visitTaskInfo.BeforeConvertedTaskId,
});
result.ReadingTaskState = visitTaskInfo.ReadingTaskState;
var taskInfoList = await _generalCalculateService.GetReadingReportTaskList(indto.VisitTaskId);
result.VisitTaskList = taskInfoList;
var visitTaskIds = taskInfoList.Select(x => x.VisitTaskId).ToList();
var criterionId = visitTaskInfo.TrialReadingCriterionId;
var questionList = await _readingQuestionTrialRepository.Where(x => x.ReadingQuestionCriterionTrialId == criterionId && x.ShowQuestion != ShowQuestion.Hide)
.WhereIf(isConvertTask, x => x.ConvertShowType == ConvertShowType.All || x.ConvertShowType == ConvertShowType.AfterShow)
.WhereIf(!isConvertTask, x => x.ConvertShowType == ConvertShowType.All || x.ConvertShowType == ConvertShowType.BeforeShow)
.ToListAsync();
var tableQuestionList = await _readingTableQuestionTrialRepository.Where(x => x.TrialCriterionId == criterionId).OrderBy(x => x.ShowOrder).ToListAsync();
var tableAnsweRowInfos = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == indto.VisitTaskId).ProjectTo<TableAnsweRowInfo>(_mapper.ConfigurationProvider).ToListAsync();
result.LesionCountList = tableAnsweRowInfos.GroupBy(x => x.LesionType).Select(x => new LesionDto
{
LesionType = x.Key!.Value,
Count = x.ToList().Count()
}).ToList();
var lesionsIndexs = await _readingTableAnswerRowInfoRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).GroupBy(x => new { x.QuestionId }).Select(x => new lesionsIndexDto()
{
QuestionId = x.Key.QuestionId,
Rowindexs = x.Select(x => x.RowIndex).Distinct().OrderBy(x => x).ToList()
}).ToListAsync();
var answers = await _readingTaskQuestionAnswerRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).ToListAsync();
var tableAnswers = await _readingTableQuestionAnswerRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).ToListAsync();
var globalanswerList = await _readingGlobalTaskInfoRepository.Where(x => visitTaskIds.Contains(x.TaskId) && x.GlobalVisitTask.TaskState == TaskState.Effect && x.Answer != string.Empty).Select(x => new
{
x.TaskId,
x.GlobalVisitTask.VisitTaskNum,
x.QuestionId,
x.Answer
}).ToListAsync();
var alltableAnsweRowInfos = await _readingTableAnswerRowInfoRepository.Where(x => visitTaskIds.Contains(x.VisitTaskId)).ToListAsync();
var organIds = alltableAnsweRowInfos.Where(x => x.OrganInfoId != null).Select(x => x.OrganInfoId).Distinct().ToList();
var organInfos = await _organInfoRepository.Where(x => organIds.Contains(x.Id)).ToListAsync();
var needChangeType = new List<QuestionMark?>() {
QuestionMark.Organ,
QuestionMark.Location,
QuestionMark.Part,
};
// 第一级
#region 构造问题
List<ReadingReportDto> questions = questionList.Where(x => x.Type == ReadingQestionType.Group).OrderBy(x => x.ShowOrder).Select(x => new ReadingReportDto()
{
QuestionId = x.Id,
GroupName = x.GroupName,
GroupEnName = x.GroupEnName,
IsShowInDicom = x.IsShowInDicom,
Type = x.Type,
GroupId = x.GroupId,
QuestionType = x.QuestionType,
LesionType = x.LesionType,
QuestionGenre = x.QuestionGenre,
DataSource = x.DataSource,
DictionaryCode = x.DictionaryCode,
TypeValue = x.TypeValue,
QuestionName = x.QuestionName.LanguageName(x.QuestionEnName, _userInfo.IsEn_Us),
ShowOrder = x.ShowOrder,
ValueType = x.ValueType,
Unit = x.Unit,
CustomUnit = x.CustomUnit,
ReportLayType = ReportLayType.Group,
HighlightAnswer = x.HighlightAnswer,
HighlightAnswerList = x.HighlightAnswerList,
}).ToList();
// 分组
foreach (var item in questions)
{
item.Childrens = questionList.Where(x => x.GroupId == item.QuestionId).OrderBy(x => x.ShowOrder).Select(x => new ReadingReportDto()
{
GroupName = x.GroupName,
QuestionId = x.Id,
IsShowInDicom = x.IsShowInDicom,
GroupEnName = x.GroupEnName,
QuestionName = x.QuestionName.LanguageName(x.QuestionEnName, _userInfo.IsEn_Us),
LesionType = x.LesionType,
QuestionGenre = x.QuestionGenre,
DataSource = x.DataSource,
DictionaryCode = x.DictionaryCode,
Type = x.Type,
QuestionType = x.QuestionType,
TypeValue = x.TypeValue,
ShowOrder = x.ShowOrder,
OrderMark = x.OrderMark,
ValueType = x.ValueType,
Unit = x.Unit,
CustomUnit = x.CustomUnit,
ReportLayType = ReportLayType.Question,
HighlightAnswer = x.HighlightAnswer,
HighlightAnswerList = x.HighlightAnswerList,
}).ToList();
// 问题
foreach (var question in item.Childrens)
{
foreach (var task in taskInfoList)
{
var globalAnswer = globalanswerList.Where(x => x.TaskId == task.VisitTaskId && x.QuestionId == question.QuestionId).OrderByDescending(x => x.VisitTaskNum).FirstOrDefault();
var answer = answers.Where(x => x.VisitTaskId == task.VisitTaskId && x.ReadingQuestionTrialId == question.QuestionId).FirstOrDefault();
question.Answer.Add(new TaskQuestionAnswer()
{
Answer = answer == null ? string.Empty : answer.Answer,
IsGlobalChange = globalAnswer == null ? false : true,
GlobalChangeAnswer = globalAnswer == null ? string.Empty : globalAnswer.Answer,
TaskName = task.TaskName,
VisitTaskId = task.VisitTaskId,
});
}
// 构造表格行数据
var rowlist = tableAnsweRowInfos.Where(x => x.QuestionId == question.QuestionId).OrderBy(x => x.RowIndex).ToList();
question.Childrens = new List<ReadingReportDto>();
var rowoindexs = lesionsIndexs.Where(x => x.QuestionId == question.QuestionId).Select(x => x.Rowindexs.OrderBy(y => y).ToList()).FirstOrDefault();
rowoindexs = rowoindexs == null ? new List<decimal>() : rowoindexs;
foreach (var rowoindex in rowoindexs)
{
var rowinfo = rowlist.Where(x => x.RowIndex == rowoindex).FirstOrDefault();
question.Childrens.Add(new ReadingReportDto()
{
QuestionName = question.OrderMark + rowoindex.GetLesionMark(),
RowId = rowinfo?.Id,
IsShowInDicom = question.IsShowInDicom,
SplitOrMergeLesionName = rowinfo != null ? (rowinfo.MergeName.IsNullOrEmpty() ? rowinfo.SplitName : rowinfo.MergeName) : string.Empty,
SplitOrMergeType = rowinfo != null ? (rowinfo.SplitOrMergeType) : null,
LesionType = question.LesionType,
IsCanEditPosition = rowinfo != null ? (rowinfo.IsCanEditPosition) : false,
RowIndex = rowoindex,
BlindName = rowinfo != null ? rowinfo.BlindName : string.Empty,
ReportLayType = ReportLayType.Lesions,
ReportMark = rowinfo != null ? rowinfo.ReportMark : string.Empty,
});
}
foreach (var row in question.Childrens)
{
// tableQuestion
row.Childrens = tableQuestionList.Where(x => x.ReadingQuestionId == question.QuestionId).Select(x => new ReadingReportDto()
{
QuestionName = x.QuestionName.LanguageName(x.QuestionEnName, _userInfo.IsEn_Us),
QuestionId = x.ReadingQuestionId,
TableQuestionId = x.Id,
Type = x.Type,
LesionType = question.LesionType,
TableQuestionType = x.TableQuestionType,
RowId = row.RowId,
IsShowInDicom = question.IsShowInDicom,
DataSource = x.DataSource,
DictionaryCode = x.DictionaryCode,
QuestionMark = x.QuestionMark,
TypeValue = x.TypeValue,
RowIndex = row.RowIndex,
ShowOrder = x.ShowOrder,
ValueType = x.ValueType,
Unit = x.Unit,
ReportLayType = ReportLayType.TableQuestion,
}).ToList();
foreach (var tableQuestion in row.Childrens)
{
foreach (var task in taskInfoList)
{
var rowinfo = alltableAnsweRowInfos.Where(x => x.VisitTaskId == task.VisitTaskId && x.QuestionId == tableQuestion.QuestionId && x.RowIndex == tableQuestion.RowIndex).FirstOrDefault();
var taskQuestionAnswer = new TaskQuestionAnswer()
{
Answer = tableAnswers.Where(x => x.VisitTaskId == task.VisitTaskId && x.QuestionId == tableQuestion.QuestionId && x.RowIndex == tableQuestion.RowIndex && x.TableQuestionId == tableQuestion.TableQuestionId).Select(x => x.Answer).FirstIsNullReturnEmpty(),
TaskName = task.TaskName,
VisitTaskId = task.VisitTaskId,
};
if (rowinfo != null && rowinfo.OrganInfoId != null)
{
var organInfo = organInfos.Where(x => x.Id == rowinfo.OrganInfoId).FirstOrDefault();
if (organInfo != null && needChangeType.Contains(tableQuestion.QuestionMark))
{
if (_userInfo.IsEn_Us)
{
switch (tableQuestion.QuestionMark)
{
case QuestionMark.Organ:
taskQuestionAnswer.Answer = organInfo.TULOCEN;
break;
case QuestionMark.Location:
if (organInfo.IsCanEditPosition)
{
}
else
{
taskQuestionAnswer.Answer = organInfo.TULATEN;
}
break;
case QuestionMark.Part:
taskQuestionAnswer.Answer = organInfo.PartEN;
break;
}
}
else
{
switch (tableQuestion.QuestionMark)
{
case QuestionMark.Organ:
taskQuestionAnswer.Answer = organInfo.TULOC;
break;
case QuestionMark.Location:
if (organInfo.IsCanEditPosition)
{
}
else
{
taskQuestionAnswer.Answer = organInfo.TULAT;
}
break;
case QuestionMark.Part:
taskQuestionAnswer.Answer = organInfo.Part;
break;
}
}
}
}
tableQuestion.Answer.Add(taskQuestionAnswer);
}
}
}
};
}
#endregion
result.TaskQuestions = questions;
return result;
}
#endregion
/// <summary>
/// 测试计算
/// </summary>
/// <param name="visitTaskId"></param>
/// <param name="type"></param>
/// <returns></returns>
[HttpGet]
public async Task TestCalculate(Guid visitTaskId, QuestionType? type)
{
//_logger.LogError("测试计算");
ReadingCalculateDto readingData = await _generalCalculateService.GetReadingCalculateDto(visitTaskId);
// await _generalCalculateService.LogRecord(readingData, "其他既往新病灶", LesionType.OtherPreviousNewLesion);
if (type == null)
{
await ReadingCalculate(readingData);
}
else
{
await ReadingCalculate(readingData, new List<QuestionType>() { type.Value });
}
}
/// <summary>
/// 计算任务
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
[HttpPost]
public async Task CalculateTask(CalculateTaskInDto inDto)
{
ReadingCalculateDto readingData = await _generalCalculateService.GetReadingCalculateDto(inDto.VisitTaskId);
readingData.IsChangeOtherTask = inDto.IsChangeOtherTask;
await ReadingCalculate(readingData);
}
/// <summary>
/// 获取报告验证的信息(这里每个标准可能不一样 返回用object)
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<GetReportVerifyOutDto> GetReportVerify(GetReportVerifyInDto inDto)
{
var tumorEvaluate = string.Empty;
var readingCalculateDto = await _generalCalculateService.GetReadingCalculateDto(inDto.VisitTaskId);
if (!inDto.IsConvertTask)
{
tumorEvaluate = await GetTumor(readingCalculateDto);
}
else if (inDto.BeforeConvertedTaskId != null)
{
tumorEvaluate = await GetConvertingTumor(readingCalculateDto);
}
else
{
tumorEvaluate = await GetIRECSITTargetLesionEvaluate(readingCalculateDto);
}
return new GetReportVerifyOutDto()
{
TumorEvaluate = tumorEvaluate,
IsExistDisease = await this.GetReportIsExistDisease(inDto.VisitTaskId),
};
}
/// <summary>
/// 自动计算
/// </summary>
/// <param name="inDto"></param>
/// <param name="calculateType"></param>
/// <returns></returns>
public async Task ReadingCalculate(ReadingCalculateDto inDto, List<QuestionType>? calculateType = null)
{
#region 计算 这里顺序非常重要 后面计算的值要依赖前面计算的结果
var needAddList = new List<ReadingTaskQuestionAnswerDto>();
List<ReadingCalculateData> calculateList = new List<ReadingCalculateData>()
{
//靶病灶径线之和（SOD）
new ReadingCalculateData (){QuestionType=QuestionType.SOD,GetDecimalNullFun=GetSODData},
//非淋巴结靶病灶长径之和
new ReadingCalculateData (){QuestionType=QuestionType.SumOfDiameter,GetDecimalNullFun=GetSumOfDiameter},
//与基线SOD相比变化量（mm）
new ReadingCalculateData (){QuestionType=QuestionType.SODChange,GetDecimalNullFun=GetSODChange},
//与基线访视相比SOD变化百分比
new ReadingCalculateData (){QuestionType=QuestionType.SODPercent,GetDecimalNullFun=GetSODPercent},
//与整个访视期间SOD最低点相比增加的值（mm）
new ReadingCalculateData (){QuestionType=QuestionType.LowestIncrease,GetDecimalNullFun=GetLowestIncrease,/*ChangeAllTaskFun=ChangeAllLowestIncrease*/},
//与整个访视期间SOD最低点相比增加的百分比
new ReadingCalculateData (){QuestionType=QuestionType.LowPercent,GetDecimalNullFun=GetLowPercent,/*ChangeAllTaskFun=ChangeAllLowPercent*/},
//整个访视期间SOD最低点访视名称
new ReadingCalculateData (){QuestionType=QuestionType.LowVisit,GetStringFun=GetLowVisit,/*ChangeAllTaskFun=ChangeAllLowVisitName*/},
//是否存在非淋巴结靶病灶
new ReadingCalculateData (){QuestionType=QuestionType.IsLymphTarget,GetStringFun=GetIsLymphTarget},
//是否存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上
new ReadingCalculateData (){QuestionType=QuestionType.IsAddFive,GetStringFun=GetIsAddFive},
//被评估为NE的单个靶病灶
new ReadingCalculateData (){QuestionType=QuestionType.NETarget,GetStringFun=GetNETarget},
// 与触发iRECIST访视相比SOD变化量
new ReadingCalculateData (){QuestionType=QuestionType.ComparedTriggeringSODChange,GetStringFun=GetComparedTriggeringSODChange,IsConvertedTask=true},
// 新靶病灶直径之和（iSOD）
new ReadingCalculateData (){QuestionType=QuestionType.ISOD,GetDecimalNullFun=GetiSODData,IsConvertedTask=true},
// 与触发iRECIST访视相比iSOD变化量
new ReadingCalculateData (){QuestionType=QuestionType.ComparedTriggeringiSODChange,GetStringFun=GetComparedTriggeringiSODChange,IsConvertedTask=true},
// 靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.TargetLesion,GetStringFun=GetTargetLesionEvaluate,IsConvertedTask=false},
// IRECIST靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.TargetLesion,GetStringFun=GetIRECISTTargetLesionEvaluate,IsConvertedTask=true},
// 转化时靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.TargetLesion,GetStringFun=GetConvertingTargetLesionEvaluate,IsConvertedTask=true,IsBeTransforming=true},
//非靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.NoTargetLesion,GetStringFun=GetNoTargetLesionEvaluate,IsConvertedTask=false},
//IRECIST非靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.NoTargetLesion,GetStringFun=GetIRECISTNoTargetLesionEvaluate,IsConvertedTask=true},
// 转化时非靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.NoTargetLesion,GetStringFun=GetConvertingNoTargetLesionEvaluate,IsConvertedTask=true ,IsBeTransforming=true},
// IRECIST新靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.NewTargetLesion,GetStringFun=GetNewTargetLesionEvaluate,IsConvertedTask=true},
// IRECIST新非靶病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.NewNoTargetLesion,GetStringFun=GetNewNoTargetLesionEvaluate,IsConvertedTask=true},
// IRECIST其它既往新病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.OtherNewTargetLesion,GetStringFun=GetOtherNewTargetLesionEvaluate,IsConvertedTask=true},
// IRECIST触发iRECIST后新病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.IRECISTNewTargetLesion,GetStringFun=GetNewLesionAfterTriggeringiRECSITAssessment,IsConvertedTask=true},
//IRECIST新病灶评估
new ReadingCalculateData (){QuestionType=QuestionType.NewLesionEvaluation,GetStringFun=GetNewLesionAssessment,IsConvertedTask=true},
//是否存在新病灶
new ReadingCalculateData (){QuestionType=QuestionType.NewLesions,GetStringFun=GetNewLesionEvaluate,IsConvertedTask=false},
// IRECIST是否存在新病灶 IRECIST
new ReadingCalculateData (){QuestionType=QuestionType.NewLesions,GetStringFun=GetNewLesionIRECSITEvaluate,IsConvertedTask=true},
//是否存在疾病
new ReadingCalculateData (){QuestionType=QuestionType.ExistDisease,GetStringFun=GetIsExistDisease},
//整体肿瘤评估
new ReadingCalculateData (){QuestionType=QuestionType.Tumor,GetStringFun=GetTumor,IsConvertedTask=false},
// 转化时整体肿瘤评估
new ReadingCalculateData (){QuestionType=QuestionType.Tumor,GetStringFun=GetConvertingTumor,IsConvertedTask=true,IsBeTransforming=true},
//IRECIST整体肿瘤评估
new ReadingCalculateData (){QuestionType=QuestionType.Tumor,GetStringFun=GetIRECSITTargetLesionEvaluate,IsConvertedTask=true},
};
// 过滤转化的
calculateList = calculateList.Where(x => x.IsConvertedTask == inDto.IsConvertedTask || x.IsConvertedTask == null).ToList();
if (inDto.IsConvertedTask)
{
if (inDto.BeforeConvertedTaskId != null)
{
List<QuestionType> questionTypes = calculateList.Where(x => x.IsBeTransforming).Select(x => x.QuestionType).ToList();
// 排除这几个 且不为正在转化的
calculateList = calculateList.Where(x => !(questionTypes.Contains(x.QuestionType) && x.IsBeTransforming == false)).ToList();
}
else
{
calculateList = calculateList.Where(x => x.IsBeTransforming == false).ToList();
}
}
// 没有靶病灶只计算最后几个
if (inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).Sum(x => x.TableRowInfoList.Count()) == 0)
{
List<QuestionType> questionTypes = new List<QuestionType>()
{
QuestionType.ISOD,
QuestionType.ComparedTriggeringiSODChange,
QuestionType.ComparedTriggeringSODChange,
QuestionType.TargetLesion,
QuestionType.NoTargetLesion,
QuestionType.NewLesions,
QuestionType.Tumor,
QuestionType.ExistDisease,
QuestionType.NewTargetLesion,
QuestionType.NewNoTargetLesion,
QuestionType.OtherNewTargetLesion,
QuestionType.IRECISTNewTargetLesion,
QuestionType.NewLesionEvaluation,
};
// 没有靶病灶就删除其他几个答案的值
var isNeedDeleteTypes = calculateList.Where(x => !questionTypes.Contains(x.QuestionType)).Select(x => x.QuestionType).ToList();
var isNeedDeleteIds = inDto.QuestionInfo.Where(x => x.QuestionType != null && isNeedDeleteTypes.Contains(x.QuestionType.Value)).Select(x => x.QuestionId).ToList();
await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => x.VisitTaskId == inDto.VisitTaskId && isNeedDeleteIds.Contains(x.ReadingQuestionTrialId), x => new ReadingTaskQuestionAnswer
{
Answer = string.Empty
});
calculateList = calculateList.Where(x => questionTypes.Contains(x.QuestionType)).ToList();
}
if (calculateType != null)
{
calculateList = calculateList.Where(x => calculateType.Contains(x.QuestionType)).ToList();
}
var typeNAList = new List<QuestionType>
{
QuestionType.SODChange,
QuestionType.SODPercent,
QuestionType.LowestIncrease,
QuestionType.LowPercent,
};
foreach (var calculate in calculateList)
{
var item = inDto.QuestionInfo.FirstOrDefault(x => x.QuestionType == calculate.QuestionType);
if (item != null)
{
//计算答案
if (inDto.IsOnlyChangeAllTask == false)
{
#region 计算答案
if (calculate.GetDecimalFun != null)
{
item.Answer = (await calculate.GetDecimalFun(inDto)).ToString();
}
else if (calculate.GetDecimalNullFun != null)
{
var value = await calculate.GetDecimalNullFun(inDto);
if (value == null)
{
if (typeNAList.Contains(item.QuestionType ?? QuestionType.SOD))
{
item.Answer = nameof(YesOrNoOrNa.NA);
}
else
{
item.Answer = this.nAString;
}
}
else
{
item.Answer = value == null ? "" : value.Value.ToString();
}
}
else if (calculate.GetStringFun != null)
{
item.Answer = await calculate.GetStringFun(inDto);
}
#endregion
// 修改修约小数位数
List<ValueOfType?> valueOfTypes = new List<ValueOfType?>() {
ValueOfType.Decimals,
ValueOfType.Percentage
};
if (inDto.DigitPlaces != -1)
{
try
{
if (valueOfTypes.Contains(item.ValueType))
{
item.Answer = decimal.Round(decimal.Parse(item.Answer ?? "0"), inDto.DigitPlaces).ToString("F" + inDto.DigitPlaces.ToString());
}
}
catch (Exception)
{
}
}
needAddList.Add(new ReadingTaskQuestionAnswerDto()
{
Answer = item.Answer,
QuestionType = calculate.QuestionType,
ReadingQuestionTrialId = item.QuestionId,
});
}
// 修改全局
if (inDto.IsChangeOtherTask && calculate.ChangeAllTaskFun != null)
{
await calculate.ChangeAllTaskFun(new ChangeAllTaskDto()
{
calculateDto = inDto,
QuestionId = item.QuestionId,
});
}
}
}
var questionIds = needAddList.Select(x => x.ReadingQuestionTrialId).ToList();
await _readingTaskQuestionAnswerRepository.BatchDeleteNoTrackingAsync(x => questionIds.Contains(x.ReadingQuestionTrialId) && x.VisitTaskId == inDto.VisitTaskId);
// 这里在某些条件下 要删除 sod变化量 和isod变化量
// 靶病灶评估为IUPD或者ICPD
var targetLesionIsIUorIC = needAddList.Any(x => x.QuestionType == QuestionType.TargetLesion && (x.Answer.EqEnum(TargetAssessment.iUPD) || x.Answer.EqEnum(TargetAssessment.iCPD)));
// 新靶病灶为IUPD或者ICPD
var newTargetLesionIsIUorIC = needAddList.Any(x => x.QuestionType == QuestionType.NewTargetLesion && (x.Answer.EqEnum(NewTargetLesionAssessment.iUPD) || x.Answer.EqEnum(NewTargetLesionAssessment.iCPD)));
needAddList.ForEach(x =>
{
if (x.QuestionType == QuestionType.ComparedTriggeringSODChange && !targetLesionIsIUorIC)
{
x.Answer = string.Empty;
}
else if (x.QuestionType == QuestionType.ComparedTriggeringiSODChange && !newTargetLesionIsIUorIC)
{
x.Answer = string.Empty;
}
x.SubjectId = inDto.SubjectId;
x.ReadingQuestionCriterionTrialId = inDto.CriterionId;
x.VisitTaskId = inDto.VisitTaskId;
x.TrialId = inDto.TrialId;
x.SubjectId = inDto.SubjectId;
});
await _readingTaskQuestionAnswerRepository.AddRangeAsync(needAddList);
await _readingTaskQuestionAnswerRepository.SaveChangesAsync();
#endregion
}
///// <summary>
///// 获取报告整体整体评估
///// </summary>
///// <param name="visitTaskId"></param>
///// <returns></returns>
//public async Task<string> GetReportTumor(Guid visitTaskId)
//{
// return await GetTumor(await _generalCalculateService.GetReadingCalculateDto(visitTaskId));
//}
/// <summary>
/// 获取报告是否存在疾病
/// </summary>
/// <param name="visitTaskId"></param>
/// <returns></returns>
public async Task<string> GetReportIsExistDisease(Guid visitTaskId)
{
return await GetIsExistDisease(await _generalCalculateService.GetReadingCalculateDto(visitTaskId));
}
/// <summary>
/// 验证访视提交
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task VerifyVisitTaskQuestions(VerifyVisitTaskQuestionsInDto inDto)
{
if (await _readingTaskQuestionAnswerRepository.AnyAsync(x => x.ReadingQuestionTrial.QuestionType == QuestionType.ImageQualityAssessment && x.VisitTaskId == inDto.VisitTaskId && x.Answer == ImageQualityEvaluation.Abnormal.GetEnumInt()))
{
return;
}
var tableAnswerList = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.VisitTaskId && (x.Answer == string.Empty || x.Answer == null)
&& x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.State
)
.Select(x => new
{
x.ReadingQuestionTrial.OrderMark,
x.RowIndex,
QuestionMark = x.ReadingTableQuestionTrial.QuestionMark,
Answer = x.Answer,
}).ToListAsync();
string errorMassage = string.Empty;
var rowAnswerList = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == inDto.VisitTaskId && (x.MeasureData == string.Empty || x.MeasureData == null))
.Select(x => new
{
x.ReadingQuestionTrial.OrderMark,
x.RowIndex,
x.Id,
}).ToListAsync();
var unableEvaluateRowIds = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.VisitTaskId
&& x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.State
).Where(x =>
(x.ReadingQuestionTrial.LesionType == LesionType.TargetLesion && x.Answer == TargetState.UnableEvaluate.GetEnumInt())
|| (x.ReadingQuestionTrial.LesionType == LesionType.NewLesions && x.Answer == NewLesionState.UnableEvaluate.GetEnumInt())
|| (x.ReadingQuestionTrial.LesionType == LesionType.NonTargetLesions && x.Answer == NoTargetState.UnableEvaluate.GetEnumInt())
|| (x.ReadingQuestionTrial.LesionType == LesionType.NewTargetLesion && x.Answer == NewTargetLesionState.NotEvaluable.GetEnumInt())
|| (x.ReadingQuestionTrial.LesionType == LesionType.NewNonTargetLesion && x.Answer == NewNoTargetLesionState.NotEvaluable.GetEnumInt())
|| (x.ReadingQuestionTrial.LesionType == LesionType.OtherPreviousNewLesion && x.Answer == OtherPreviousNewLesionState.NotEvaluable.GetEnumInt())
|| (x.ReadingQuestionTrial.LesionType == LesionType.TriggeringIRECSIT && x.Answer == NewLesionAfterTriggeringiRECSITState.NotEvaluable.GetEnumInt())
)
.Select(x => x.RowId).Distinct().ToListAsync();
List<string> measureDataList = rowAnswerList.Where(x => !unableEvaluateRowIds.Contains(x.Id)).Select(x => x.OrderMark + x.RowIndex.GetLesionMark()).ToList();
List<string> stateIsNullList = tableAnswerList.Select(x => x.OrderMark + x.RowIndex.GetLesionMark()).ToList();
List<string> allExists = measureDataList.Intersect(stateIsNullList).ToList();
measureDataList = measureDataList.Except(allExists).ToList();
stateIsNullList = stateIsNullList.Except(allExists).ToList();
if (measureDataList.Count() > 0)
{
errorMassage += _localizer["ReadingCalculate_NoMarker", string.Join(',', measureDataList)] + ",";
}
if (tableAnswerList.Count > 0)
{
errorMassage += _localizer["ReadingCalculate_StatusIsEmpty", string.Join(',', stateIsNullList)] + ",";
}
if (allExists.Count > 0)
{
errorMassage += _localizer["ReadingCalculate_NoMarkerEmpty", string.Join(',', stateIsNullList)] + ",";
}
if (errorMassage != string.Empty)
{
throw new BusinessValidationFailedException(errorMassage);
}
}
#region 将上一次的访视病灶添加到这一次
/// <summary>
/// 将上一次的访视病灶添加到这一次
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<AddTaskLesionAnswerFromLastTaskOutDto> AddTaskLesionAnswerFromLastTask(AddTaskLesionAnswerFromLastTaskInDto inDto)
{
var visitTaskId = inDto.VisitTaskId;
var taskinfo = await _visitTaskRepository.Where(x => x.Id == visitTaskId).ProjectTo<VisitTaskDto>(_mapper.ConfigurationProvider).FirstNotNullAsync();
var baseLineVisitId = await _subjectVisitRepository.Where(x => x.SubjectId == taskinfo.SubjectId && x.IsBaseLine).Select(x => x.Id).FirstOrDefaultAsync();
// 判断当前任务是否是基线
if (taskinfo.SourceSubjectVisitId != baseLineVisitId)
{
// 判断当前任务是是否有表格问题答案
if (!(await _readingTableQuestionAnswerRepository.AnyAsync(x => x.VisitTaskId == visitTaskId)))
{
if (taskinfo.BeforeConvertedTaskId != null)
{
await _generalCalculateService.AddConvertedTaskFocus(taskinfo.Id, taskinfo.BeforeConvertedTaskId.Value);
}
else
{
var LastVisitTaskId = await _visitTaskRepository.Where(x => x.ReadingCategory == ReadingCategory.Visit &&
x.TrialReadingCriterionId == taskinfo.TrialReadingCriterionId &&
x.IsAnalysisCreate == taskinfo.IsAnalysisCreate &&
x.DoctorUserId == taskinfo.DoctorUserId &&
x.IsSelfAnalysis == taskinfo.IsSelfAnalysis &&
x.SubjectId == taskinfo.SubjectId && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == taskinfo.ArmEnum
&& x.VisitTaskNum < taskinfo.VisitTaskNum && x.TaskState == TaskState.Effect
).OrderByDescending(x => x.VisitTaskNum).Select(x => x.Id).FirstOrDefaultAsync();
var copyTableAnswers = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == LastVisitTaskId).Select(x => new CopyTableAnswerDto()
{
Answer = x.Answer,
QuestionId = x.QuestionId,
RowId = x.RowId,
QuestionMark = x.ReadingTableQuestionTrial.QuestionMark,
TableQuestionId = x.TableQuestionId,
RowIndex = x.RowIndex,
TrialId = x.TrialId
}).ToListAsync();
var tableRowAnswers = await _readingTableAnswerRowInfoRepository.Where(x => x.VisitTaskId == LastVisitTaskId).ProjectTo<CopyTableAnswerRowInfo>(_mapper.ConfigurationProvider).ToListAsync();
tableRowAnswers.ForEach(x =>
{
x.VisitTaskId = visitTaskId;
x.IsCurrentTaskAdd = false;
x.Id = NewId.NextGuid();
x.SeriesId = null;
x.InstanceId = null;
x.MeasureData = string.Empty;
x.PicturePath = string.Empty;
});
tableRowAnswers.ForEach(x =>
{
x.SplitRowId = tableRowAnswers.Where(y => y.OriginalId == x.SplitRowId).Select(y => y.Id).FirstOrDefault();
x.MergeRowId = tableRowAnswers.Where(y => y.OriginalId == x.MergeRowId).Select(y => y.Id).FirstOrDefault();
});
List<QuestionMark?> notNeedCopyMarks = new List<QuestionMark?>()
{
QuestionMark.MajorAxis,
QuestionMark.ShortAxis,
QuestionMark.State,
};
//if (taskinfo.IsConvertedTask)
//{
// notNeedCopyMarks = new List<QuestionMark?>()
//{
// QuestionMark.MajorAxis,
// QuestionMark.ShortAxis,
//};
//}
var tableAnswers = copyTableAnswers.Select(x => new ReadingTableQuestionAnswer
{
Id = NewId.NextGuid(),
Answer = notNeedCopyMarks.Contains(x.QuestionMark) ? string.Empty : x.Answer,
QuestionId = x.QuestionId,
RowIndex = x.RowIndex,
RowId = tableRowAnswers.Where(y => y.OriginalId == x.RowId).Select(x => x.Id).FirstOrDefault(),
TableQuestionId = x.TableQuestionId,
TrialId = x.TrialId,
VisitTaskId = visitTaskId,
});
var addList = _mapper.Map<List<ReadingTableAnswerRowInfo>>(tableRowAnswers);
await _readingTableAnswerRowInfoRepository.AddRangeAsync(addList);
await _readingTableQuestionAnswerRepository.AddRangeAsync(tableAnswers);
await _readingTableQuestionAnswerRepository.SaveChangesAsync();
}
}
}
return new AddTaskLesionAnswerFromLastTaskOutDto()
{
IsBaseLine = taskinfo.SourceSubjectVisitId == baseLineVisitId,
};
}
#endregion
#region 获取SOD
/// <summary>
/// 获取SOD
/// </summary>
/// <remarks>
/// 靶病灶径线之和（SOD）
/// 非淋巴结的长径 和淋巴结的短径
/// </remarks>
/// <returns></returns>
public async Task<decimal?> GetSODData(ReadingCalculateDto inDto)
{
if (sODData != null)
{
return sODData.Value;
}
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
if (tableQuestion.Count() == 0)
{
return null;
}
decimal result = 0;
foreach (var item in tableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
// 淋巴结的短径
result += (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0();
}
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.No)))
{
// 非淋巴结的长径
result += item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
}
}
sODData = result;
return sODData.Value;
}
#endregion
#region 非淋巴结靶病灶长径之和
/// <summary>
/// 非淋巴结靶病灶长径之和
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<decimal?> GetSumOfDiameter(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
if (tableQuestion.Count() == 0)
{
return null;
}
decimal result = 0;
foreach (var item in tableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.No)))
{
// 非淋巴结的长径
result += item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
}
}
return result;
}
#endregion
#region 与基线SOD相比变化量（mm）
/// <summary>
/// 与基线SOD相比变化量（mm）
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<decimal?> GetSODChange(ReadingCalculateDto inDto)
{
var value = await GetSODData(inDto);
if (value == null || inDto.IsBaseLine)
{
return null;
}
return value.NullChange0() - await GetBaseLineSOD(inDto);
}
#endregion
#region 与基线访视相比SOD变化百分比
/// <summary>
/// 与基线访视相比SOD变化百分比
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<decimal?> GetSODPercent(ReadingCalculateDto inDto)
{
var thisSOD = await GetSODData(inDto);
if (thisSOD == null || inDto.IsBaseLine)
{
return null;
}
var baseLineSOD = await GetBaseLineSOD(inDto);
if (baseLineSOD == 0)
{
return 100;
}
else
{
return (thisSOD.NullChange0() - baseLineSOD) * 100 / baseLineSOD;
}
}
#endregion
#region 与整个访视期间SOD最低点相比增加的值（mm）
/// <summary>
/// 与整个访视期间SOD最低点相比增加的值（mm）
/// </summary>
/// <param name="inDto"></param>
/// <remarks>
/// 要更新之前的
/// </remarks>
/// <returns></returns>
public async Task<decimal?> GetLowestIncrease(ReadingCalculateDto inDto)
{
var value = await GetSODData(inDto);
if (value == null || inDto.IsBaseLine)
{
return null;
}
var decimalAnswerList = await GetLowSODVisit(inDto);
var minSOD = decimalAnswerList.OrderBy(x => x.SOD).Select(x => x.SOD).FirstOrDefault();
return value.NullChange0() - minSOD;
}
#endregion
#region 与整个访视期间SOD最低点相比增加的百分比
/// <summary>
/// 与整个访视期间SOD最低点相比增加的百分比
/// </summary>
/// <param name="inDto"></param>
/// <remarks>
/// 要更新之前的
/// </remarks>
/// <returns></returns>
public async Task<decimal?> GetLowPercent(ReadingCalculateDto inDto)
{
var thisSOD = await GetSODData(inDto);
if (thisSOD == null || inDto.IsBaseLine)
{
return null;
}
var decimalAnswerList = await GetLowSODVisit(inDto);
var minSOD = decimalAnswerList.OrderBy(x => x.SOD).Select(x => x.SOD).FirstOrDefault();
if (minSOD == 0)
{
return 100;
}
else
{
return (thisSOD.NullChange0() - minSOD) * 100 / minSOD;
}
}
#endregion
#region 整个访视期间SOD最低点访视名称
/// <summary>
/// 整个访视期间SOD最低点访视名称
/// </summary>
/// <param name="inDto"></param>
/// <remarks>
/// 要更新之前的
/// </remarks>
/// <returns></returns>
public async Task<string> GetLowVisit(ReadingCalculateDto inDto)
{
if (inDto.IsBaseLine)
{
return nameof(YesOrNoOrNa.NA);
}
var targetCount = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).Count();
if (targetCount == 0)
{
return nameof(YesOrNoOrNa.NA);
}
var decimalAnswerList = await GetLowSODVisit(inDto);
return decimalAnswerList.OrderBy(x => x.SOD).Select(x => x.BlindName).FirstOrDefault() ?? string.Empty;
}
#endregion
#region 是否存在非淋巴结靶病灶
/// <summary>
/// 是否存在非淋巴结靶病灶
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetIsLymphTarget(ReadingCalculateDto inDto)
{
var result = IsLymph.No.GetEnumInt();
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
foreach (var item in tableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(IsLymph.No)))
{
result = IsLymph.Yes.GetEnumInt();
}
}
return result;
}
#endregion
#region 是否存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上
/// <summary>
/// 是否存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetIsAddFive(ReadingCalculateDto inDto)
{
if (inDto.IsBaseLine)
{
return YesOrNoOrNa.NA.GetEnumInt();
}
var addFiveList = await GetIsAddFiveRowIndexs(inDto);
var isExists = addFiveList.Count() > 0 ? true : false;
return isExists ? YesOrNoOrNa.Yes.GetEnumInt() : YesOrNoOrNa.No.GetEnumInt();
}
/// <summary>
/// 获取存在淋巴结靶病灶且该病灶比上一访视短径增加5MM以上的病灶
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<List<decimal>> GetIsAddFiveRowIndexs(ReadingCalculateDto inDto)
{
List<decimal> result = new List<decimal>();
var LastVisitTaskId = await this.GetLastVisitTaskId(inDto);
var questionIds = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).Select(x => x.QuestionId).ToList();
var lastQuestionAsnwer = await _readingTableQuestionAnswerRepository.Where(x => x.VisitTaskId == LastVisitTaskId && questionIds.Contains(x.QuestionId)).Include(x => x.ReadingQuestionTrial).Include(x => x.ReadingTableQuestionTrial).ToListAsync();
var rowIndexs = lastQuestionAsnwer.Where(x => x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)).Select(x => x.RowIndex).Distinct().OrderBy(x => x).ToList();
var thisQuestionAsnwer = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
foreach (var item in rowIndexs)
{
var lastValue = lastQuestionAsnwer.Where(x => x.RowIndex == item && x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
var thisRowData = thisQuestionAsnwer.Where(x => x.RowIndex == item).SelectMany(x => x.TableQuestionList).ToList();
var thisValue = thisRowData.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
if (thisValue - lastValue >= 5)
{
result.Add(item);
}
}
return result;
}
#endregion
#region 被评估为NE的单个靶病灶
/// <summary>
/// 被评估为NE的单个靶病灶
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNETarget(ReadingCalculateDto inDto)
{
if (inDto.IsBaseLine)
{
return ExistOrNA.NA.GetEnumInt();
}
var result = inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.NE));
return result ? ExistOrNA.Exist.GetEnumInt() : ExistOrNA.NotExist.GetEnumInt();
}
#endregion
#region 整体肿瘤评估
/// <summary>
/// 整体肿瘤评估
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetTumor(ReadingCalculateDto inDto)
{
if (inDto.IsBaseLine)
{
return OverallAssessment.NA.GetEnumInt();
}
var targetLesion = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.TargetLesion).Select(x => x.Answer).FirstOrDefault();
var noTargetLesion = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NoTargetLesion).Select(x => x.Answer).FirstOrDefault();
var newLesions = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewLesions).Select(x => x.Answer).FirstOrDefault();
var result = await _tumorAssessmentRepository.Where(x =>
x.TargetLesion == (TargetAssessment)int.Parse(targetLesion.IsNullOrEmpty() ? TargetAssessment.NA.GetEnumInt() : targetLesion) &&
x.NonTargetLesions == (NoTargetAssessment)int.Parse(noTargetLesion.IsNullOrEmpty() ? NoTargetAssessment.NA.GetEnumInt() : noTargetLesion) &&
x.NewLesion == (NewLesionAssessment)int.Parse(newLesions.IsNullOrEmpty() ? NewLesionAssessment.NA.GetEnumInt() : newLesions)).Select(x => x.OverallEfficacy).ToListAsync();
return result.Count == 0 ? OverallAssessment.NE.GetEnumInt() : result[0].GetEnumInt();
}
#endregion
#region 是否存在疾病
/// <summary>
/// 是否存在疾病
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetIsExistDisease(ReadingCalculateDto inDto)
{
if (!inDto.IsBaseLine)
{
return string.Empty;
}
var lesionCount = inDto.QuestionInfo.SelectMany(x => x.TableRowInfoList).Count();
return lesionCount > 0 ? ExistDisease.Yes.GetEnumInt() : ExistDisease.No.GetEnumInt();
}
#endregion
#region 与触发iRECIST访视相比SOD变化量
/// <summary>
/// 与触发iRECIST访视相比SOD变化量
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetComparedTriggeringSODChange(ReadingCalculateDto inDto)
{
var compareTaskId = await this.GetCompareTaskId(inDto, QuestionType.TargetLesion);
if (compareTaskId == null)
{
return string.Empty;
}
var lastTaskId = await GetLastVisitTaskId(inDto);
// 靶病灶评估为IUPD或者ICPD
var targetLesionIsIUorIC = await _readingTaskQuestionAnswerRepository.AnyAsync(x => x.VisitTaskId == lastTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.TargetLesion && (x.Answer == TargetAssessment.iUPD.GetEnumInt() || x.Answer == TargetAssessment.iCPD.GetEnumInt()));
if (!targetLesionIsIUorIC)
{
return string.Empty;
}
var compareTaskSOD = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == compareTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.SOD).Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0();
var value = await GetSODData(inDto);
if (value == null || inDto.IsBaseLine || !inDto.IsConvertedTask || inDto.BeforeConvertedTaskId != null)
{
return string.Empty;
}
return (value.NullChange0() - compareTaskSOD).ToString();
}
#endregion
#region 新靶病灶直径之和（iSOD）
/// <summary>
/// 获取iSOD
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<decimal?> GetiSODData(ReadingCalculateDto inDto)
{
if (!inDto.IsConvertedTask)
{
return null;
}
if (iSODData != null)
{
return iSODData.Value;
}
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
if (tableQuestion.Count() == 0)
{
return null;
}
decimal result = 0;
foreach (var item in tableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
// 淋巴结的短径
result += (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0();
}
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.No)))
{
// 非淋巴结的长径
result += item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault().IsNullOrEmptyReturn0();
}
}
iSODData = result;
return iSODData.Value;
}
#endregion
#region 与触发iRECIST访视相比iSOD变化量
/// <summary>
/// 与触发iRECIST访视相比iSOD变化量
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetComparedTriggeringiSODChange(ReadingCalculateDto inDto)
{
var compareTaskId = await this.GetCompareTaskId(inDto, QuestionType.NewTargetLesion);
if (compareTaskId == null)
{
return string.Empty;
}
var lastTaskId = await GetLastVisitTaskId(inDto);
// 新靶病灶为IUPD或者ICPD
var newTargetLesionIsIUorIC = await _readingTaskQuestionAnswerRepository.AnyAsync(x => x.VisitTaskId == lastTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.NewTargetLesion && (x.Answer == NewTargetLesionAssessment.iUPD.GetEnumInt() || x.Answer == NewTargetLesionAssessment.iCPD.GetEnumInt()));
if (!newTargetLesionIsIUorIC)
{
return string.Empty;
}
var compareTaskiSOD = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == compareTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.ISOD).Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0();
var value = await GetiSODData(inDto);
if (value == null || inDto.IsBaseLine || !inDto.IsConvertedTask || inDto.BeforeConvertedTaskId != null)
{
return string.Empty;
}
return (value.NullChange0() - compareTaskiSOD).ToString();
}
#endregion
#region 修改其他标准
#region 修改与整个访视期间SOD最低点相比增加的值（mm）
/// <summary>
/// 修改与整个访视期间SOD最低点相比增加的值（mm）
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task ChangeAllLowestIncrease(ChangeAllTaskDto inDto)
{
var visitTaskList = await GetVisitTaskAnswerList(inDto.calculateDto);
var lowSod = (await GetLowSODVisit(inDto.calculateDto)).Select(x => x.SOD).OrderBy(x => x).FirstOrDefault();
foreach (var item in visitTaskList.Where(x => x.VisitTaskId != inDto.calculateDto.BaseLineTaskId))
{
await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => x.VisitTaskId == item.VisitTaskId && x.ReadingQuestionTrialId == inDto.QuestionId, x => new ReadingTaskQuestionAnswer()
{
Answer = (item.SOD - lowSod).ToString()
});
}
}
#endregion
#region 修改整个访视期间SOD最低点相比增加的百分比
/// <summary>
/// 修改整个访视期间SOD最低点相比增加的百分比
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
//public async Task ChangeAllLowPercent(ChangeAllTaskDto inDto)
//{
// var visitTaskList = await GetVisitTaskAnswerList(inDto.calculateDto);
// var lowSod = (await GetLowSODVisit(inDto.calculateDto)).Select(x => x.SOD).OrderBy(x => x).FirstOrDefault();
// foreach (var item in visitTaskList.Where(x => x.VisitTaskId != inDto.calculateDto.BaseLineTaskId))
// {
// decimal percent = 0;
// if (lowSod == 0)
// {
// percent = 100;
// }
// else
// {
// percent = decimal.Round((item.SOD - lowSod) * 100 / lowSod, 2);
// }
// await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => x.VisitTaskId == item.VisitTaskId && x.ReadingQuestionTrialId == inDto.QuestionId, x => new ReadingTaskQuestionAnswer()
// {
// Answer = percent.ToString()
// });
// }
//}
#endregion
#region 修改最低方式点名称
/// <summary>
/// 修改最低方式点名称
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task ChangeAllLowVisitName(ChangeAllTaskDto inDto)
{
// 找到所有访视任务的Id
var visitTaskIds = await _visitTaskRepository.Where(x => x.IsAnalysisCreate == inDto.IsAnalysisCreate &&
x.ReadingCategory == ReadingCategory.Visit &&
x.TrialReadingCriterionId == inDto.calculateDto.TrialReadingCriterionId &&
x.TaskState == TaskState.Effect && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == inDto.calculateDto.ArmEnum).Select(x => x.Id).ToListAsync();
var answer = (await GetLowSODVisit(inDto.calculateDto)).OrderBy(x => x.SOD).Select(x => x.BlindName).FirstOrDefault();
visitTaskIds = visitTaskIds.Where(x => x != inDto.calculateDto.BaseLineTaskId).ToList();
await this.ChangeAllVisitTaskAnswer(visitTaskIds, inDto.QuestionId, answer);
}
#endregion
#endregion
#region 通用方法
#region 修改所有访视任务的答案
/// <summary>
/// 修改所有访视任务的答案
/// </summary>
/// <param name="visitTaskGuids"></param>
/// <param name="questionId"></param>
/// <param name="answer"></param>
/// <returns></returns>
private async Task ChangeAllVisitTaskAnswer(List<Guid> visitTaskGuids, Guid questionId, string answer)
{
await _readingTaskQuestionAnswerRepository.BatchUpdateNoTrackingAsync(x => visitTaskGuids.Contains(x.VisitTaskId) && x.ReadingQuestionTrialId == questionId, x => new ReadingTaskQuestionAnswer()
{
Answer = answer
});
}
#endregion
#region 获取基线SOD
/// <summary>
/// 获取基线SOD
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
private async Task<decimal> GetBaseLineSOD(ReadingCalculateDto inDto)
{
if (await _visitTaskRepository.AnyAsync(x => x.Id == inDto.VisitTaskId && x.SourceSubjectVisit.IsBaseLine && x.IsAnalysisCreate == inDto.IsAnalysisCreate && x.ArmEnum == inDto.ArmEnum))
{
return 0;
}
// 先找到基线的任务
var baseLineTaskId = await _visitTaskRepository.Where(x => x.SubjectId == inDto.SubjectId && x.ReadingCategory == ReadingCategory.Visit
&& x.TrialReadingCriterionId == inDto.TrialReadingCriterionId &&
x.SourceSubjectVisit.IsBaseLine && x.TaskState == TaskState.Effect &&
x.IsAnalysisCreate == inDto.IsAnalysisCreate
&& x.DoctorUserId == inDto.DoctorUserId
&& x.IsSelfAnalysis == inDto.IsSelfAnalysis && x.ArmEnum == inDto.ArmEnum)
.Select(x => x.Id).FirstOrDefaultAsync();
var baseLineSOD = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == baseLineTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.SOD).Select(x => x.Answer).FirstOrDefaultAsync()).IsNullOrEmptyReturn0();
return baseLineSOD;
}
#endregion
/// <summary>
/// 获取最低方式
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<List<VisitTaskAnswerInfo>> GetLowSODVisit(ReadingCalculateDto inDto)
{
var taskAnswerList = await GetVisitTaskAnswerList(inDto);
taskAnswerList = taskAnswerList.Where(x => x.VisitTaskId != inDto.VisitTaskId).ToList();
var taskIds = taskAnswerList.Select(x => x.VisitTaskId).ToList();
// 排除无法评估
var unableEvaluateTaskIds = await _readingTableQuestionAnswerRepository.Where(x => taskIds.Contains(x.VisitTaskId) &&
x.ReadingTableQuestionTrial.QuestionMark == QuestionMark.State
&& x.ReadingQuestionTrial.LesionType == LesionType.TargetLesion
&& x.Answer == TargetState.UnableEvaluate.GetEnumInt()
)
.Select(x => x.VisitTaskId).Distinct().ToListAsync();
taskAnswerList = taskAnswerList.Where(x => !unableEvaluateTaskIds.Contains(x.VisitTaskId)).ToList();
return taskAnswerList.OrderBy(x => x.SOD).ToList();
}
#region 获取访视任务信息
/// <summary>
/// 获取访视任务信息
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<List<VisitTaskAnswerInfo>> GetVisitTaskAnswerList(ReadingCalculateDto inDto)
{
if (visitTaskAnswerList == null)
{
// 查询的时候要把自己排除 因为查询出来的可能不是计算出的最新的
visitTaskAnswerList = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId != inDto.VisitTaskId && x.VisitTask.ReadingCategory == ReadingCategory.Visit
&& x.VisitTask.IsAnalysisCreate == inDto.IsAnalysisCreate
&& x.VisitTask.IsSelfAnalysis == inDto.IsSelfAnalysis
&& x.ReadingQuestionCriterionTrialId == inDto.TrialReadingCriterionId
&& x.VisitTask.VisitTaskNum < inDto.VisitTaskNum
&& x.SubjectId == inDto.SubjectId && x.VisitTask.ReadingTaskState == ReadingTaskState.HaveSigned && x.VisitTask.ArmEnum == inDto.ArmEnum && x.VisitTask.TaskState == TaskState.Effect && x.ReadingQuestionTrial.QuestionType == QuestionType.SOD)
.Select(x => new VisitTaskAnswerInfo
{
VisitTaskId = x.VisitTaskId,
QuestionId = x.ReadingQuestionTrialId,
VisitName = x.VisitTask.SourceSubjectVisit.VisitName,
BlindName = x.VisitTask.TaskBlindName,
SOD = x.Answer.IsNullOrEmptyReturn0(),
}).ToListAsync();
// 这里是需要加上自己的 基线不用管
if (visitTaskAnswerList.Count > 0)
{
visitTaskAnswerList.Add(new VisitTaskAnswerInfo()
{
VisitTaskId = inDto.VisitTaskId,
BlindName = inDto.TaskBlindName,
QuestionId = visitTaskAnswerList[0].QuestionId,
VisitName = inDto.VisitName,
SOD = (await GetSODData(inDto)).ToString().IsNullOrEmptyReturn0(),
});
}
}
return visitTaskAnswerList;
}
#endregion
/// <summary>
/// 获取上一个访视任务Id
/// </summary>
/// <returns></returns>
private async Task<Guid> GetLastVisitTaskId(ReadingCalculateDto inDto)
{
if (lastVisitTaskId != null)
{
return lastVisitTaskId.Value;
}
else
{
var taskinfo = await _visitTaskRepository.Where(x => x.Id == inDto.VisitTaskId).ProjectTo<VisitTaskDto>(_mapper.ConfigurationProvider).FirstNotNullAsync();
var lastTaskId = await _visitTaskRepository.Where(x => x.ReadingCategory == ReadingCategory.Visit &&
x.TrialReadingCriterionId == taskinfo.TrialReadingCriterionId &&
x.IsAnalysisCreate == taskinfo.IsAnalysisCreate &&
x.DoctorUserId == taskinfo.DoctorUserId &&
x.IsSelfAnalysis == taskinfo.IsSelfAnalysis &&
x.SubjectId == taskinfo.SubjectId && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == taskinfo.ArmEnum
&& x.VisitTaskNum < taskinfo.VisitTaskNum && x.TaskState == TaskState.Effect
).OrderByDescending(x => x.VisitTaskNum).Select(x => x.Id).FirstOrDefaultAsync();
lastVisitTaskId = lastTaskId;
return lastTaskId;
}
}
/// <summary>
/// 获取比较任务Id 需要之前一次访视为IUPD或者ICPD
/// </summary>
/// <returns></returns>
private async Task<Guid?> GetCompareTaskId(ReadingCalculateDto inDto, QuestionType questionType)
{
var taskinfo = await _visitTaskRepository.Where(x => x.Id == inDto.VisitTaskId).ProjectTo<VisitTaskDto>(_mapper.ConfigurationProvider).FirstNotNullAsync();
var lastTaskId = await GetLastVisitTaskId(inDto);
if (compareTaskList == null)
{
// 先找到第一个转变任务的number 直接找是否为转变任务 查询耗性能
var firstChangeVisitTaskNum = await _visitTaskRepository.Where(x => x.ReadingCategory == ReadingCategory.Visit &&
x.TrialReadingCriterionId == taskinfo.TrialReadingCriterionId &&
x.IsAnalysisCreate == taskinfo.IsAnalysisCreate &&
x.DoctorUserId == taskinfo.DoctorUserId &&
x.IsSelfAnalysis == taskinfo.IsSelfAnalysis &&
x.SubjectId == taskinfo.SubjectId && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == taskinfo.ArmEnum
&& x.BeforeConvertedTaskId != null && x.TaskState == TaskState.Effect
).OrderBy(x => x.VisitTaskNum).Select(x => x.VisitTaskNum).FirstOrDefaultAsync();
// 找到转变之后 所有任务
compareTaskList = await _visitTaskRepository.Where(x => x.ReadingCategory == ReadingCategory.Visit &&
x.TrialReadingCriterionId == taskinfo.TrialReadingCriterionId &&
x.IsAnalysisCreate == taskinfo.IsAnalysisCreate &&
x.DoctorUserId == taskinfo.DoctorUserId &&
x.IsSelfAnalysis == taskinfo.IsSelfAnalysis &&
x.SubjectId == taskinfo.SubjectId && x.ReadingTaskState == ReadingTaskState.HaveSigned && x.ArmEnum == taskinfo.ArmEnum &&
x.VisitTaskNum >= firstChangeVisitTaskNum && x.VisitTaskNum < taskinfo.VisitTaskNum && x.TaskState == TaskState.Effect
).OrderBy(x => x.VisitTaskNum).Select(x => new TirggerTaskInfo()
{
VisitTaskId = x.Id,
VisitNum = x.VisitTaskNum,
}).ToListAsync();
// 获取所有任务Id
var visitTaskids = compareTaskList.Select(x => x.VisitTaskId).ToList();
// 找到所有任务的靶病灶评估和非靶病灶评估
var answers = await _readingTaskQuestionAnswerRepository.Where(x => (x.ReadingQuestionTrial.QuestionType == QuestionType.TargetLesion || x.ReadingQuestionTrial.QuestionType == QuestionType.NewTargetLesion) &&
visitTaskids.Contains(x.VisitTaskId)
).Select(x => new TirggerAnswerInfo()
{
VisitTaskId = x.VisitTaskId,
Answer = x.Answer,
QuestionType = x.ReadingQuestionTrial.QuestionType!.Value
}).ToListAsync();
compareTaskList.ForEach(y =>
{
y.TargetAssessmentIsIUorIC = answers.Any(x => x.VisitTaskId == y.VisitTaskId && x.QuestionType == QuestionType.TargetLesion && (x.Answer == TargetAssessment.iUPD.GetEnumInt() || x.Answer == TargetAssessment.iCPD.GetEnumInt()));
y.NewTargetLesionAssessmentIsIUorIC = answers.Any(x => x.VisitTaskId == y.VisitTaskId && x.QuestionType == QuestionType.NewTargetLesion && (x.Answer == NewTargetLesionAssessment.iUPD.GetEnumInt() || x.Answer == NewTargetLesionAssessment.iCPD.GetEnumInt()));
});
}
Guid? compareTaskId = null;
if (compareTaskList.Count() == 0)
{
return compareTaskId;
}
switch (questionType)
{
case QuestionType.TargetLesion:
for (int i = compareTaskList.Count() - 1; i >= 0; i--)
{
if (i == 0)
{
return compareTaskList[0].VisitTaskId;
}
else
{
if (compareTaskList[i].TargetAssessmentIsIUorIC && !compareTaskList[i - 1].TargetAssessmentIsIUorIC)
{
return compareTaskList[i].VisitTaskId;
}
}
}
break;
case QuestionType.NewTargetLesion:
for (int i = compareTaskList.Count() - 1; i >= 0; i--)
{
if (i == 0)
{
return compareTaskList[0].VisitTaskId;
}
else
{
if (compareTaskList[i].NewTargetLesionAssessmentIsIUorIC && !compareTaskList[i - 1].NewTargetLesionAssessmentIsIUorIC)
{
return compareTaskList[i].VisitTaskId;
}
}
}
break;
}
return compareTaskId;
}
#endregion
#region 计算阅片问题 外层问题
#region IRECIST计算
#region 获取IRECIST靶病灶评估
/// <summary>
/// 获取IRECIST靶病灶评估
/// </summary>
/// <param name="inDto"></param>
/// <remarks>
/// if（基线没有靶病灶）
/// {
/// 靶病灶疗效为 ND
/// }
/// else if (上一访视评估为iCPD && 本次访视满足RECIST1.1的PD条件)
/// {
/// 靶病灶疗效为 ICPD
/// }
/// else if (上一访视评估为iUPD&&与触发iRECIST访视相比本次访视SOD增加不小于5mm)
/// {
/// 靶病灶疗效为 ICPD
/// }
/// else if (本次访视满足RECIST1.1的PD条件 )
/// {
/// 靶病灶疗效为 iUPD
/// } else if (有任一靶病灶为NE状态)
/// {
/// 靶病灶疗效为 NE
/// }
/// else if (所有非淋巴结靶病灶消失，径线总和为0 mm && 所有淋巴结靶病灶的短径缩小到 < 10 mm && 非靶病灶中淋巴结病灶全部消失)
/// {
/// 靶病灶疗效为 iCR
/// } else if (与基线期SOD相比减小≥30 %||(所有非淋巴结靶病灶消失，径线总和为0 mm && 所有淋巴结靶病灶的短径缩小到 < 10 mm&&非靶病灶中有淋巴结病灶为非消失))
/// {
/// 靶病灶疗效为 iPR
/// }
/// else
/// {
/// 靶病灶疗效为 iSD
/// }
///
/// </remarks>
/// <returns></returns>
public async Task<string> GetIRECISTTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
var targetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.TargetLesion).Select(x => x.QuestionId).FirstOrDefault();
var sodQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SOD).Select(x => x.QuestionId).FirstOrDefault();
IRECISTTargetLesionDto resultData = new IRECISTTargetLesionDto()
{
// 基线没有靶病灶
NotExistsTargetLesion = tableQuestion.Count() == 0,
// 上一访视评估
LastTaskTarget = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == targetLesionQuestionId)
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
// 满足RECISTPD
MeetRECISTPD = (await GetTargetLesionEvaluate(inDto)) == TargetAssessment.PD.GetEnumInt(),
// 本次访视SOD与触发iRECIST访视相比本次访视SOD增加不小于5mm
SODTiggerAddGreaterThan5 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.ComparedTriggeringSODChange).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 5,
//比整体访视期间最低点SOD增加≥20 %
LowSodAddGreaterThan20Percent = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 20,
// 比整体访视期间最低点SOD绝对增加值≥5 mm
LowSodAddGreaterThan5 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowestIncrease).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 5,
// 当前访视至少有一个“存在”状态的靶病灶
HaveExistLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.Exist)),
// 有任一靶病灶为NE状态
HaveNeLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.UnableEvaluate)),
// 所有非淋巴结靶病灶消失，径线总和为0
AllLesionVanish = true,
// 所有淋巴结靶病灶的短径缩小到 < 10 mm
AllMinorAxisLessThan10 = true,
// 与基线期SOD相比减小≥30 %
BaseLineLessThan30 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) <= -30,
//非靶病灶中淋巴结病灶全部消失
NoTargetLymphLoss = true,
};
var noTargetTableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList).ToList();
foreach (var item in noTargetTableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
resultData.NoTargetLymphLoss = resultData.NoTargetLymphLoss && item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.State).Select(x => x.Answer).FirstOrDefault() == NoTargetState.Loss.GetEnumInt();
}
}
foreach (var item in tableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
// 淋巴结的短径
resultData.AllMinorAxisLessThan10 = resultData.AllMinorAxisLessThan10 && (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() < 10;
}
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && !x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
resultData.AllLesionVanish = resultData.AllLesionVanish && item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.State).Select(x => x.Answer).FirstOrDefault() == TargetState.Loss.GetEnumInt();
}
}
TargetAssessment result = TargetAssessment.SD;
// if（基线没有靶病灶）
if (resultData.NotExistsTargetLesion)
{
// 靶病灶疗效为 ND
result = TargetAssessment.ND;
}
// else if (上一访视评估为iCPD && 本次访视满足RECIST1.1的PD条件)
else if (resultData.LastTaskTarget.EqEnum(TargetAssessment.iCPD) && resultData.MeetRECISTPD)
{
// 靶病灶疗效为 ICPD
result = TargetAssessment.iCPD;
}
// else if (上一访视评估为iUPD&&与触发iRECIST访视相比本次访视SOD增加不小于5mm)
else if (resultData.LastTaskTarget.EqEnum(TargetAssessment.iUPD) && resultData.SODTiggerAddGreaterThan5)
{
// 靶病灶疗效为 ICPD
result = TargetAssessment.iCPD;
}
// } else if (本次访视满足RECIST1.1的PD条件 )
else if (resultData.MeetRECISTPD)
{
// 靶病灶疗效为 iUPD
result = TargetAssessment.iUPD;
}
// else if (有任一靶病灶为NE状态)
else if (resultData.HaveNeLesion)
{
// 靶病灶疗效为 NE
result = TargetAssessment.NE;
}
// else if (所有非淋巴结靶病灶消失，径线总和为0 mm && 所有淋巴结靶病灶的短径缩小到 < 10 mm && 非靶病灶中淋巴结病灶全部消失)
else if (resultData.AllLesionVanish && resultData.AllMinorAxisLessThan10 && resultData.NoTargetLymphLoss)
{
// 靶病灶疗效为 iCR
result = TargetAssessment.iCR;
}
// else if (与基线期SOD相比减小≥30 %||(所有非淋巴结靶病灶消失，径线总和为0 mm && 所有淋巴结靶病灶的短径缩小到 < 10 mm&&非靶病灶中有淋巴结病灶为非消失))
else if (resultData.BaseLineLessThan30 || (resultData.AllLesionVanish && resultData.AllMinorAxisLessThan10 && !resultData.NoTargetLymphLoss))
{
// 靶病灶疗效为 iPR
result = TargetAssessment.iPR;
}
// else
else
{
// 靶病灶疗效为 iSD
result = TargetAssessment.iSD;
}
return result.GetEnumInt();
}
#endregion
#region IRECIST非靶病灶评估
/// <summary>
/// IRECIST非靶病灶评估
/// </summary>
/// <remarks>
/// if（基线没有非靶病灶）
/// {
/// 非靶病灶疗效为 ND
/// }
/// else if (上次非靶病灶评估结果为iUPD && (任一非靶病灶状态评估为“进一步增大（iCPD）||出现至少1个上一访视未评估为“显著增大（iUPD）”的病灶本次访视评估为“显著增大（iUPD）”))
/// {
/// 非靶病灶疗效为 iCPD
/// }
/// else if (上次非靶病灶评估结果为iCPD && 任一非靶病灶状态评估为“进一步增大（iCPD）”或“显著增大（iUPD）”)
/// {
/// 非靶病灶疗效为 iCPD
/// }
/// else if (满足RECIST1.1的PD标准)
/// {
/// 非靶病灶疗效为 iUPD
/// }
/// else if (有任一非靶病灶为NE状态)
/// {
/// 非靶病灶疗效为 NE
/// }
/// else if (全部非靶病灶均为“消失”状态)
/// {
/// 非靶病灶疗效为 iCR
/// }
/// else
/// {
/// 非靶病灶疗效为 iNN
/// }
/// </remarks>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetIRECISTNoTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList).ToList();
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
var noTargetQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NoTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
// 找上一次任务 未被评为显著增大的非靶病灶
ReadingCalculateDto lastTaskCalculateDto = await _generalCalculateService.GetReadingCalculateDto(lastVisitTaskId);
var lastTaskNoiUPDIndexs = lastTaskCalculateDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList)
.Where(x => x.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && !x.Answer.EqEnum(NoTargetState.IUPD))).Select(x => x.RowIndex).ToList();
IRECISTNoTargetLesion data = new IRECISTNoTargetLesion()
{
// 基线没有非靶病灶
NotExistsNoTargetLesion = tableQuestion.Count() == 0,
// 上次非靶病灶评估结果
LastNoTargetLesion = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == noTargetQuestionId)
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
// 任一非靶病灶状态评估为“进一步增大（iCPD）”
ExistiCPD = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.ICPD)),
// 出现至少1个上一访视未评估为“显著增大（iUPD）”的病灶本次访视评估为“显著增大（iUPD）”
LastNoUPD = tableQuestion.Where(x => lastTaskNoiUPDIndexs.Contains(x.RowIndex)).SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.IUPD)),
// 任一非靶病灶状态评估为 iUPD
ExistiUPD = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.IUPD)),
// 满足RECIST1.1PD
RECISTPD = (await GetNoTargetLesionEvaluate(inDto)).EqEnum(NoTargetAssessment.PD),
// 有任一非靶病灶为NE状态
HaveNeLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.UnableEvaluate)),
// 全部为消失
AllVanish = true,
};
foreach (var item in tableQuestion)
{
data.AllVanish = data.AllVanish && item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Loss));
}
NoTargetAssessment result = NoTargetAssessment.iNN;
// if（基线没有非靶病灶）
if (data.NotExistsNoTargetLesion)
{
// 非靶病灶疗效为 ND
result = NoTargetAssessment.ND;
}
// else if (上次非靶病灶评估结果为iUPD && (任一非靶病灶状态评估为“进一步增大（iCPD）||出现至少1个上一访视未评估为“显著增大（iUPD）”的病灶本次访视评估为“显著增大（iUPD）”))
else if (data.LastNoTargetLesion.EqEnum(NoTargetAssessment.iUPD) && (data.ExistiCPD || data.LastNoUPD))
{
// 非靶病灶疗效为 iCPD
result = NoTargetAssessment.iCPD;
}
// else if (上次非靶病灶评估结果为iCPD && 任一非靶病灶状态评估为“进一步增大（iCPD）”或“显著增大（iUPD）”)
else if (data.LastNoTargetLesion.EqEnum(NoTargetAssessment.iCPD) && (data.ExistiCPD || data.ExistiUPD))
{
// 非靶病灶疗效为 iCPD
result = NoTargetAssessment.iCPD;
}
// else if (满足RECIST1.1的PD标准)
else if (data.RECISTPD)
{
// 非靶病灶疗效为 iUPD
result = NoTargetAssessment.iUPD;
}
// else if (有任一非靶病灶为NE状态)
else if (data.HaveNeLesion)
{
// 非靶病灶疗效为 NE
result = NoTargetAssessment.NE;
}
// else if (全部非靶病灶均为“消失”状态)
else if (data.AllVanish)
{
// 非靶病灶疗效为 iCR
result = NoTargetAssessment.iCR;
}
// else
else
{
// 非靶病灶疗效为 iNN
result = NoTargetAssessment.iNN;
}
return result.GetEnumInt();
}
#endregion
#region IRECIST新靶病灶评估
/// <summary>
/// 获取IRECIST新靶病灶评估
/// </summary>
/// <remarks>
/// if（所有新靶病灶消失或一直不存在任何新靶病灶）
/// {
/// 疗效为 ND
/// }
/// else if (上一访视新靶病灶评估为“iUPD” && 与触发iRECIS任务iSod增加大于5mm)
/// {
/// 疗效为 iCPD
/// }
/// else if (上一访视新靶病灶评估为“iCPD”&& （当有“存在”状态的淋巴结新靶病灶||当有“存在”或“太小”状态的非淋巴结新靶病灶）)
/// {
/// 疗效为 iCPD
/// }
/// else if (当有“存在”状态的淋巴结新靶病灶||当有“存在”或“太小”状态的非淋巴结新靶病灶)
/// {
/// 疗效为 iUPD
/// }
/// else if (至少有一个新靶病无法评估)
/// {
/// 疗效为 NE
/// }
/// else
///{
/// //错误级别日志：项目、标准、受试者、阅片人、任务。输出新靶病灶数据：
///}
/// </remarks>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNewTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
if (inDto.IsBaseLine)
{
return TargetAssessment.NA.GetEnumInt();
}
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
var newTargetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
var isodQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.ISOD).Select(x => x.QuestionId).FirstOrDefault();
IRECISTNewTargetLesionDto data = new IRECISTNewTargetLesionDto()
{
// 不存在新靶病灶
NotExistsNewTargetLesion = tableQuestion.Count() == 0,
// 所有状态为消失
AllVanish = true,
// 上一访视新靶病灶评估
LastTaskNewTargetLesion = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == newTargetLesionQuestionId)
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
//与触发iRECIS任务iSod增加大于5mm
ISODAdd5mm = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.ComparedTriggeringiSODChange).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 5,
//有"存在"状态的新靶病灶
HaveExixtsState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Exist)),
// 至少有一个新靶病无法评估
ExixtsUnevaluableState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.NotEvaluable)),
// 当有“存在”状态的淋巴结新靶病灶
ExixtsLymphTarget = false,
// 当有“存在”或“太小”状态的非淋巴结新靶病灶
ExixtsOrLessNoLymphTarget = false,
};
foreach (var item in tableQuestion)
{
data.AllVanish = data.AllVanish && item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Loss));
data.ExixtsLymphTarget = data.ExixtsLymphTarget ||
(
item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Exist)) &&
item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes))
);
data.ExixtsOrLessNoLymphTarget = data.ExixtsOrLessNoLymphTarget ||
(
(
item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Exist))
|| item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.TooSmall))
)
&&
item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && !x.Answer.EqEnum(YesOrNoOrNa.Yes))
);
}
NewTargetLesionAssessment? result = NewTargetLesionAssessment.ND;
// if（所有新靶病灶消失或一直不存在任何新靶病灶）
if (data.NotExistsNewTargetLesion || data.AllVanish)
{
// 疗效为 ND
result = NewTargetLesionAssessment.ND;
}
// else if (上一访视新靶病灶评估为“iUPD” && 与触发iRECIS任务iSod增加大于5mm)
else if (data.LastTaskNewTargetLesion.EqEnum(NewTargetLesionAssessment.iUPD) && data.ISODAdd5mm)
{
// 疗效为 iCPD
result = NewTargetLesionAssessment.iCPD;
}
// else if (上一访视新靶病灶评估为“iCPD”&& （当有“存在”状态的淋巴结新靶病灶||当有“存在”或“太小”状态的非淋巴结新靶病灶）)
else if (data.LastTaskNewTargetLesion.EqEnum(NewTargetLesionAssessment.iCPD) && (data.ExixtsLymphTarget || data.ExixtsOrLessNoLymphTarget))
{
// 疗效为 iCPD
result = NewTargetLesionAssessment.iCPD;
}
// else if (当有“存在”状态的淋巴结新靶病灶||当有“存在”或“太小”状态的非淋巴结新靶病灶)
else if (data.HaveExixtsState || data.ExixtsOrLessNoLymphTarget)
{
// 疗效为 iUPD
result = NewTargetLesionAssessment.iUPD;
}
// else if (至少有一个新靶病无法评估)
else if (data.ExixtsUnevaluableState)
{
// 疗效为 NE
result = NewTargetLesionAssessment.NE;
}
else
{
//错误级别日志：项目、标准、受试者、阅片人、任务。输出新靶病灶数据：
await _generalCalculateService.LogRecord(inDto, "新靶病灶", LesionType.NewTargetLesion);
}
return result == null ? string.Empty : result.Value.GetEnumInt();
}
#endregion
#region 获取新非靶病灶评估
/// <summary>
/// 获取新非靶病灶评估
/// </summary>
/// <remarks>
/// if（所有新非靶病灶消失或一直不存在任何新非靶病灶时评估为该结果）
/// {
/// 疗效为 ND
/// }
/// else if (上一访视新非靶病灶评估为“iUPD” && 满足任一新非靶病灶状态为“增大”)
/// {
/// 疗效为 iCPD
/// }
/// else if (上一访视新非靶病灶评估为“iCPD”&& 有"存在"状态的新非靶病灶)
/// {
/// 疗效为 iCPD
/// }
/// else if (当有存在状态的新非靶病灶)
/// {
/// 疗效为 iUPD
/// }
/// else if (至少有一个新非靶病无法评估)
/// {
/// 疗效为 NE
/// }
/// else
/// {
/// //错误级别日志：项目、标准、受试者、阅片人、任务。当前新非靶病灶的病灶数据输出：
/// }
/// </remarks>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNewNoTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewNonTargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
var newTargetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
var newNoTargetLesionQuestionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewNoTargetLesion).Select(x => x.QuestionId).FirstOrDefault();
IRECISTNewNoTargetLesionDto data = new IRECISTNewNoTargetLesionDto()
{
// 不存在新非靶病灶
NotExistsNewNoTargetLesion = tableQuestion.Count() == 0,
// 所有状态为消失
AllVanish = tableQuestion.Count() == tableQuestion.Where(x => x.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Loss))).Count(),
// 上一访视新非靶病灶评估
LastTaskNewNoTargetLesion = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == newNoTargetLesionQuestionId)
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty,
//当前访视的新靶病灶评估
NewTargetLesion = inDto.QuestionInfo.Where(x => x.QuestionId == newTargetLesionQuestionId).Select(x => x.Answer).FirstIsNullReturnEmpty(),
// 任一新非靶病灶状态为“增大”
ExixtsEnlargementState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Progression)),
// 有"存在"状态的病灶
HaveExixtsState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Exist)),
// 至少有一个病灶无法评估
ExixtsUnevaluableState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.NotEvaluable)),
};
NewNoTargetLesionAssessment result = NewNoTargetLesionAssessment.ND;
// if（所有新非靶病灶消失或一直不存在任何新非靶病灶时评估为该结果）
if (data.NotExistsNewNoTargetLesion || data.AllVanish)
{
// 疗效为 ND
result = NewNoTargetLesionAssessment.ND;
}
// else if (上一访视新非靶病灶评估为“iUPD” && 满足任一新非靶病灶状态为“增大”)
else if (data.LastTaskNewNoTargetLesion.EqEnum(NewNoTargetLesionAssessment.iUPD) && data.ExixtsEnlargementState)
{
// 疗效为 iCPD
result = NewNoTargetLesionAssessment.iCPD;
}
// else if (上一访视新非靶病灶评估为“iCPD”&& 有"存在"状态的新非靶病灶)
else if (data.LastTaskNewNoTargetLesion.EqEnum(NewNoTargetLesionAssessment.iCPD) && data.HaveExixtsState)
{
// 疗效为 iCPD
result = NewNoTargetLesionAssessment.iCPD;
}
// else if (当有存在状态的新非靶病灶)
else if (data.HaveExixtsState)
{
// 疗效为 iUPD
result = NewNoTargetLesionAssessment.iUPD;
}
// else if (至少有一个新非靶病无法评估)
else if (data.ExixtsUnevaluableState)
{
// 疗效为 NE
result = NewNoTargetLesionAssessment.NE;
}
else
{
// 错误级别日志：项目、标准、受试者、阅片人、任务。当前新非靶病灶的病灶数据输出：
await _generalCalculateService.LogRecord(inDto, "新非靶病灶", LesionType.NewNonTargetLesion);
}
return result.GetEnumInt();
}
#endregion
#region 其它既往新病灶评估
/// <summary>
/// 获取其它既往新病灶评估
/// </summary>
/// <remarks>
/// if（有其它既往新病灶消失或一直不存在任何其它既往新病灶）
/// {
/// 疗效为 ND
/// }
/// else if (存在状态为“明确”的其它既往新病灶)
/// {
/// 疗效为 iUPD
/// }
/// else if (至少有一个其它既往新病灶无法评估)
/// {
/// 疗效为 NE
/// }
/// else if (至少有一个其它既往新病灶为疑似状态)
/// {
/// 疗效为 疑似
/// }
/// else
/// {
/// //错误级别日志：项目、标准、受试者、阅片人、任务。输出其它既往新病灶数据：
/// }
/// </remarks>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetOtherNewTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.OtherPreviousNewLesion).SelectMany(x => x.TableRowInfoList).ToList();
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
IRECISTOtherNewTargetLesionDto data = new IRECISTOtherNewTargetLesionDto()
{
// 不存在其他既往新病灶记录
NotExistsOtherNewTargetLesion = tableQuestion.Count() == 0,
// 所有其他既往新病灶状态都为消失
AllVanish = tableQuestion.Count() == tableQuestion.Where(x => x.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Loss))).Count(),
// 存在“明确”状态
ExistsClear = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Exists)),
// 至少有一个病灶无法评估
ExixtsUnevaluableState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.NotEvaluable)),
// 至少有一个其它既往新病灶为疑似状态
ExixtsSuspectedState = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Equivocal)),
};
OtherPreviousNewLesionAssessment result = OtherPreviousNewLesionAssessment.ND;
// if（有其它既往新病灶消失或一直不存在任何其它既往新病灶）
if (data.NotExistsOtherNewTargetLesion || data.AllVanish)
{
// 疗效为 ND
result = OtherPreviousNewLesionAssessment.ND;
}
// else if (存在状态为“明确”的其它既往新病灶)
else if (data.ExistsClear)
{
// 疗效为 iUPD
result = OtherPreviousNewLesionAssessment.iUPD;
}
// else if (至少有一个其它既往新病灶无法评估)
else if (data.ExixtsUnevaluableState)
{
// 疗效为 NE
result = OtherPreviousNewLesionAssessment.NE;
}
// else if (至少有一个其它既往新病灶为疑似状态)
else if (data.ExixtsSuspectedState)
{
// 疗效为 疑似
result = OtherPreviousNewLesionAssessment.Equivocal;
}
else
{
//错误级别日志：项目、标准、受试者、阅片人、任务。输出其它既往新病灶数据：
await _generalCalculateService.LogRecord(inDto, "其它既往新病灶", LesionType.OtherPreviousNewLesion);
}
return result.GetEnumInt();
}
#endregion
#region 触发iRECIST后新病灶评估
/// <summary>
///
/// </summary>
/// <remarks>
/// if现至少1个“存在”状态的触发iRECIST后新病灶）
/// {
/// 疗效为 是
/// }
/// else if (只要有一个触发iRECIST后新病灶评估为NE)
/// {
/// 疗效为 NE
/// }
/// else if (只要有一个触发iRECIST后新病灶评估为疑似)
/// {
/// 疗效为 疑似
/// }
/// else
/// {
/// 疗效为 否
/// }
///
/// </remarks>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNewLesionAfterTriggeringiRECSITAssessment(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TriggeringIRECSIT).SelectMany(x => x.TableRowInfoList).ToList();
NewLesionAfterTriggeringiRECSITAssessment result = NewLesionAfterTriggeringiRECSITAssessment.No;
// if现至少1个“存在”状态的触发iRECIST后新病灶）
if (tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Exist)))
{
// 疗效为 是
result = NewLesionAfterTriggeringiRECSITAssessment.Yes;
}
// else if (只要有一个触发iRECIST后新病灶评估为NE)
else if (tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.NotEvaluable)))
{
// 疗效为 NE
result = NewLesionAfterTriggeringiRECSITAssessment.NE;
}
// else if (只要有一个触发iRECIST后新病灶评估为疑似)
else if (tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Equivocal)))
{
// 疗效为 疑似
result = NewLesionAfterTriggeringiRECSITAssessment.Equivocal;
}
// else
else
{
// 疗效为 否
result = NewLesionAfterTriggeringiRECSITAssessment.No;
}
return result.GetEnumInt();
}
#endregion
#region 获取新病灶评估
/// <summary>
/// 获取新病灶评估
/// </summary>
/// <remarks>
/// if(新靶病灶为ND&&新非靶病灶为ND&&其它既往新病灶为ND&&不存在触发iRECIST后新病灶）
/// {
/// 疗效为 ND
/// }
/// else if (新靶病灶为iCPD||新非靶病灶为iCPD)
/// {
/// 疗效为 iCPD
/// }
/// else if (前一访视新病灶评估为iCPD && (新靶病灶有存在病灶 || 新非靶病灶有存在状态病灶 || 其它既往新病灶有存在的病灶 || 触发iRECIST后新病灶有存在病灶))
/// {
/// 疗效为 iCPD
/// }
/// else if (前一访视新病灶评估为iUPD && 新靶病灶上个访视评估为NE，本次访视评估为iUPD)
/// {
/// 疗效为 iCPD
/// }
/// else if (前一访视新病灶评估为iUPD && 新非靶病灶上个访视评估为NE，本次访视评估为iUPD)
/// {
/// 疗效为 iCPD
/// }
/// else if (前一访视新病灶评估为iUPD && 其它既往新病灶上个访视评估为NE或疑似，本次访视评估为iUPD)
/// {
/// 疗效为 iCPD
/// }
/// else if (前一访视新病灶评估为iUPD && 触发iRECIST后新病灶评估上个访视评估为NE或否或疑似，本次访视评估为是)
/// {
/// 疗效为 iCPD
/// }
/// else if (新靶病灶评估为iUPD || 新非靶病灶评估为iUPD || 其它既往新病灶评估为iUPD || 触发iRECIST后新病灶评估上个访视评估为是)
/// {
/// 疗效为 iUPD
/// }
/// else if (新靶病灶、新非靶病灶、其它既往新病灶,触发iRECIST后新病灶 任一项评估为NE)
/// {
/// 疗效为 NE
/// }
/// else if (其它既往新病灶或触发iRECIST后新病灶评估为“疑似”)
/// {
/// 疗效为 疑似
/// }
/// else
/// {
/// //错误级别日志：项目、标准、受试者、阅片人、任务。输出新病灶数据：
/// }
/// </remarks>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNewLesionAssessment(ReadingCalculateDto inDto)
{
NewLesionAssessment? result = null;
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
ReadingCalculateDto lastTaskCalculateDto = await _generalCalculateService.GetReadingCalculateDto(lastVisitTaskId);
IRECISTNewLesionAssessmentDto data = new IRECISTNewLesionAssessmentDto()
{
//上一次任务的新病灶评估为iUPD
LastTaskNewLesioniUPD = lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.iUPD)),
//上一次任务的新病灶评估为iCPD
LastTaskNewLesioniCPD = lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.iCPD)),
// 存在触发iRECIST后新病灶
ExistxIRECISTNewLesion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TriggeringIRECSIT).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && (x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Exist) || x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Equivocal))),
};
// if(新靶病灶为ND && 新非靶病灶为ND && 其它既往新病灶为ND && 不存在触发iRECIST后新病灶）
if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.ND))
&& !data.ExistxIRECISTNewLesion)
{
// 疗效为 ND
result = NewLesionAssessment.ND;
}
// else if (新靶病灶为iCPD||新非靶病灶为iCPD)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.iCPD))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.iCPD)))
{
// 疗效为 iCPD
result = NewLesionAssessment.iCPD;
}
// else if (前一访视新病灶评估为iCPD && (新靶病灶评估为iCPD或iUPD || 新非靶病灶评估为iCPD或iUPD || 其它既往新病灶评估为iUPD || 触发iRECIST后新病灶评估为是))
else if (data.LastTaskNewLesioniCPD &&
(
inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && (x.Answer.EqEnum(NewTargetLesionAssessment.iCPD) || x.Answer.EqEnum(NewTargetLesionAssessment.iUPD)))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && (x.Answer.EqEnum(NewNoTargetLesionAssessment.iCPD) || x.Answer.EqEnum(NewNoTargetLesionAssessment.iUPD)))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.iUPD))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Yes))
)
)
{
// 疗效为 iCPD
result = NewLesionAssessment.iCPD;
}
// else if (前一访视新病灶评估为iUPD && 新靶病灶上个访视评估为NE或ND，本次访视评估为iUPD)
else if (data.LastTaskNewLesioniUPD &&
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && (x.Answer.EqEnum(NewTargetLesionAssessment.NE) || x.Answer.EqEnum(NewTargetLesionAssessment.ND)))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.iUPD))
)
{
// 疗效为 iCPD
result = NewLesionAssessment.iCPD;
}
// else if (前一访视新病灶评估为iUPD && 新非靶病灶上个访视评估为NE或ND，本次访视评估为iUPD)
else if (data.LastTaskNewLesioniUPD
&& lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && (x.Answer.EqEnum(NewNoTargetLesionAssessment.NE) || x.Answer.EqEnum(NewNoTargetLesionAssessment.ND)))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.iUPD))
)
{
// 疗效为 iCPD
result = NewLesionAssessment.iCPD;
}
// else if (前一访视新病灶评估为iUPD && 其它既往新病灶上个访视评估为NE、ND或疑似，本次访视评估为iUPD)
else if (data.LastTaskNewLesioniUPD
&& lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && (x.Answer.EqEnum(OtherPreviousNewLesionAssessment.NE) || x.Answer.EqEnum(OtherPreviousNewLesionAssessment.ND) || x.Answer.EqEnum(OtherPreviousNewLesionAssessment.Equivocal)))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.iUPD))
)
{
// 疗效为 iCPD
result = NewLesionAssessment.iCPD;
}
// else if (前一访视新病灶评估为iUPD && 触发iRECIST后新病灶评估上个访视评估为NE或否或疑似，本次访视评估为是)
else if (data.LastTaskNewLesioniUPD
&& lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && (x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.NE) || x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.No) || x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Equivocal)))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Yes))
)
{
// 疗效为 iCPD
result = NewLesionAssessment.iCPD;
}
// else if (新靶病灶评估为iUPD || 新非靶病灶评估为iUPD || 其它既往新病灶评估为iUPD || 触发iRECIST后新病灶评估为是)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.iUPD))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.iUPD))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.iUPD))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Yes))
)
{
// 疗效为 iUPD
result = NewLesionAssessment.iUPD;
}
// else if (新靶病灶、新非靶病灶、其它既往新病灶,触发iRECIST后新病灶 任一项评估为NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewTargetLesion && x.Answer.EqEnum(NewTargetLesionAssessment.NE))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewNoTargetLesion && x.Answer.EqEnum(NewNoTargetLesionAssessment.NE))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.NE))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.NE))
)
{
// 疗效为 NE
result = NewLesionAssessment.NE;
}
// else if (其它既往新病灶或触发iRECIST后新病灶评估为“疑似”)
else if (
inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.OtherNewTargetLesion && x.Answer.EqEnum(OtherPreviousNewLesionAssessment.Equivocal))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITAssessment.Equivocal))
)
{
// 疗效为 疑似
result = NewLesionAssessment.Suspected;
}
else
{
//错误级别日志：项目、标准、受试者、阅片人、任务。输出新病灶数据：
// 这里是记录日志 不需要国际化
var criterionInfo = await _readingQuestionCriterionTrialRepository.Where(x => x.Id == inDto.TrialReadingCriterionId).Include(x => x.Trial).FirstNotNullAsync();
var taskInfo = await _visitTaskRepository.Where(x => x.Id == inDto.VisitTaskId).Include(x => x.Subject).Include(x => x.DoctorUser).FirstNotNullAsync();
StringBuilder builder = new StringBuilder();
builder.AppendLine($"");
builder.AppendLine($"【项目】:【{criterionInfo.Trial.TrialCode}】");
builder.AppendLine($"【项目Id】:【{criterionInfo.TrialId}】");
builder.AppendLine($"【标准】:【{criterionInfo.CriterionName}】");
builder.AppendLine($"【标准Id】:【{criterionInfo.Id}】");
builder.AppendLine($"【受试者】:【{taskInfo.Subject.ShortName}】");
builder.AppendLine($"【受试者Id】:【{taskInfo.Subject.Id}】");
builder.AppendLine($"【阅片人】:【{taskInfo.DoctorUser.FullName}】");
builder.AppendLine($"【阅片人Id】:【{taskInfo.DoctorUser.Id}】");
builder.AppendLine($"【任务】:【{taskInfo.TaskBlindName}】");
builder.AppendLine($"【任务Id】:【{taskInfo.Id}】");
builder.AppendLine($"【病灶类型】:【新病灶】");
builder.AppendLine($"【新靶病灶评估】:【{inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewTargetLesion).Select(x => x.Answer).FirstIsNullReturnEmpty()}】");
builder.AppendLine($"【新非靶病灶评估】:【{inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewNoTargetLesion).Select(x => x.Answer).FirstIsNullReturnEmpty()}】");
builder.AppendLine($"【其它既往新病灶评估】:【{inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.OtherNewTargetLesion).Select(x => x.Answer).FirstIsNullReturnEmpty()}】");
builder.AppendLine($"【触发iRECIST后新病灶评估】:【{inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.IRECISTNewTargetLesion).Select(x => x.Answer).FirstIsNullReturnEmpty()}】");
_logger.LogError(builder.ToString());
}
return result == null ? string.Empty : ((NewLesionAssessment)result).GetEnumInt();
}
#endregion
#region 获取新病灶评估
/// <summary>
/// 获取新病灶评估
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNewLesionIRECSITEvaluate(ReadingCalculateDto inDto)
{
// 逻辑改了 现在转变后全部都是NA;
return NewLesionAssessment.NA.GetEnumInt();
//NewLesionAssessment result = NewLesionAssessment.No;
//if (inDto.IsBaseLine)
//{
// return NewLesionAssessment.NA.GetEnumInt();
//}
//var newTargetQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewTargetLesion).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
//var newNonTargetQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewNonTargetLesion).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
//var OtherPreviousNewLesionQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.OtherPreviousNewLesion).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
//var triggeringQuestions = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TriggeringIRECSIT).SelectMany(x => x.TableRowInfoList).SelectMany(x => x.TableQuestionList).ToList();
//// 当前访视存在至少一个明确新病灶
//if (newTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.Exist))
// || newNonTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.Exist))
// || OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Exists))
// || triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Exist))
// )
//{
// result = NewLesionAssessment.Yes;
//}
////只要有任何一个新病灶状态为“无法评估”
//else if (newTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewTargetLesionState.NotEvaluable))
// || newNonTargetQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewNoTargetLesionState.NotEvaluable))
// || OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.NotEvaluable))
// || triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.NotEvaluable))
// )
//{
// result = NewLesionAssessment.NE;
//}
////当前访视不存在明确新病灶且存在至少一个疑似新病灶
//else if ( (!OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Exists)) && OtherPreviousNewLesionQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(OtherPreviousNewLesionState.Equivocal)))
// || (!triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Exist)) && triggeringQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionAfterTriggeringiRECSITState.Equivocal)))
// )
//{
// result = NewLesionAssessment.Suspected;
//}
//else
//{
// result = NewLesionAssessment.No;
//}
//return result.GetEnumInt();
}
#endregion
#region iRECSIT整体肿瘤评估
/// <summary>
///
/// </summary>
/// <remarks>
/// if（上一访视整体肿瘤评估评估为iCPD && 靶病灶评估、非靶病灶评估或新病灶评估任一项为iCPD或iCPD）
/// {
/// 疗效为 iCPD
/// }
/// else if (上一访视整体肿瘤评估评估为iUPD && 靶病灶评估、非靶病灶评估或新病灶评估任一项从前一访视iUPD结果评估为当前访视iCPD)
/// {
/// 疗效为 iCPD
/// }
/// else if (上一访视整体肿瘤评估评估为iUPD && 靶病灶评估、非靶病灶评估或新病灶评估任一项从前一访视非iUPD结果评估为当前访视iUPD)
/// {
/// 疗效为 iCPD
/// }
/// else if (靶病灶评估为iUPD || 非靶病灶评估为iUPD || 新病灶评估为iUPD)
/// {
/// 疗效为 iUPD
/// }
/// else if ((靶病灶评估为iCR && 非靶病灶评估为iCR && 新病灶评估为ND)|| (靶病灶评估为ND && 非靶病灶评估为iCR && 新病灶评估为ND) || (靶病灶评估为iCR && 非靶病灶评估为ND && 新病灶评估为ND))
/// {
/// 疗效为 iCR
/// }
/// else if (靶病灶评估为iPR && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
/// {
/// 疗效为 iPR
/// }
/// else if (靶病灶评估为iCR && 非靶病灶评估为iNN或NE && 新病灶评估为ND或疑似或NE)
/// {
/// 疗效为 iPR
/// }
/// else if (靶病灶评估为iCR && 非靶病灶评估为iCR或ND && 新病灶评估为疑似或NE)
/// {
/// 疗效为 iPR
/// }
/// else if (靶病灶评估为ND && 非靶病灶评估为iCR && 新病灶评估为疑似或NE)
/// {
/// 疗效为 iPR
/// }
/// else if (靶病灶评估为iSD && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
/// {
/// 疗效为 iSD
/// }
/// else if (靶病灶评估为ND && 非靶病灶评估为iNN && 新病灶评估为ND或疑似或NE)
/// {
/// 疗效为 iNN
/// }
/// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为ND或疑似)
/// {
/// 疗效为 ND
/// }
/// else if (靶病灶评估为NE && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
/// {
/// 疗效为 NE
/// }
/// else if (靶病灶评估为ND && 非靶病灶评估为NE && 新病灶评估为ND或疑似或NE)
/// {
/// 疗效为 NE
/// }
/// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为NE)
/// {
/// 疗效为 NE
/// }
/// else
/// {
/// //错误级别日志：项目、标准、受试者、阅片人、任务。输出靶病灶、非靶病灶、新病灶的评估结果：
/// }
/// </remarks>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetIRECSITTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
ReadingCalculateDto lastTaskCalculateDto = await _generalCalculateService.GetReadingCalculateDto(lastVisitTaskId);
OverallAssessment? result = null;
IRECISTTargetLesionEvaluateDto data = new IRECISTTargetLesionEvaluateDto()
{
LastTaskLesioniUPDOriCPD = lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.Tumor && (x.Answer.EqEnum(OverallAssessment.iCPD) || x.Answer.EqEnum(OverallAssessment.iUPD))),
};
// if（上一访视整体肿瘤评估评估为iCPD && 靶病灶评估、非靶病灶评估或新病灶评估任一项为iCPD或iCPD）
if (lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.Tumor && x.Answer.EqEnum(OverallAssessment.iCPD))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && (x.Answer.EqEnum(TargetAssessment.iCPD) || x.Answer.EqEnum(TargetAssessment.iUPD)))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && (x.Answer.EqEnum(NoTargetAssessment.iCPD) || x.Answer.EqEnum(NoTargetAssessment.iUPD)))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && (x.Answer.EqEnum(NewLesionAssessment.iCPD) || x.Answer.EqEnum(NewLesionAssessment.iUPD)))))
{
// 疗效为 iCPD
result = OverallAssessment.iCPD;
}
// else if (上一访视整体肿瘤评估评估为iUPD&&靶病灶评估、非靶病灶评估或新病灶评估任一项从前一访视iUPD结果评估为当前访视iCPD)
else if (lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.Tumor && x.Answer.EqEnum(OverallAssessment.iUPD))
&& (
(
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iUPD))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iCPD))
)
||
(
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iUPD))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCPD))
)
||
(
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.iUPD)))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.iCPD))
)
)
{
// 疗效为 iCPD
result = OverallAssessment.iCPD;
}
// else if (上一访视整体肿瘤评估评估为iUPD&&靶病灶评估、非靶病灶评估或新病灶评估任一项从前一访视非iUPD结果评估为当前访视iUPD)
else if (lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.Tumor && x.Answer.EqEnum(OverallAssessment.iUPD))
&& (
(
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && !x.Answer.EqEnum(TargetAssessment.iUPD))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iUPD))
)
||
(
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && !x.Answer.EqEnum(NoTargetAssessment.iUPD))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iUPD))
)
||
(
lastTaskCalculateDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && !x.Answer.EqEnum(NewLesionAssessment.iUPD)))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.iUPD))
)
)
{
// 疗效为 iCPD
result = OverallAssessment.iCPD;
}
// else if (靶病灶评估为iUPD || 非靶病灶评估为iUPD || 新病灶评估为iUPD)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iUPD))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iUPD))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.iUPD)))
{
// 疗效为 iUPD
result = OverallAssessment.iUPD;
}
//
// else if ((靶病灶评估为iCR && 非靶病灶评估为iCR && 新病灶评估为ND) || (靶病灶评估为ND && 非靶病灶评估为iCR && 新病灶评估为ND) || (靶病灶评估为iCR && 非靶病灶评估为ND && 新病灶评估为ND))
else if (
(inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iCR))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
)
||
(inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
)
||
(inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iCR))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
)
)
{
// 疗效为 iCR
result = OverallAssessment.iCR;
}
// else if (靶病灶评估为iPR && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iPR))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 iPR
result = OverallAssessment.iPR;
}
// else if (靶病灶评估为iCR && 非靶病灶评估为iNN或NE && 新病灶评估为ND或疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iCR))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 iPR
result = OverallAssessment.iPR;
}
// else if (靶病灶评估为iCR && 非靶病灶评估为iCR或ND && 新病灶评估为疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iCR))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 iPR
result = OverallAssessment.iPR;
}
// else if (靶病灶评估为ND && 非靶病灶评估为iCR && 新病灶评估为疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 iPR
result = OverallAssessment.iPR;
}
// else if (靶病灶评估为iSD && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.iSD))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
) && (
inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 iSD
result = OverallAssessment.iSD;
}
// else if (靶病灶评估为ND && 非靶病灶评估为iNN && 新病灶评估为ND或疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 iNN
result = OverallAssessment.iNN;
}
// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为ND或疑似)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
))
{
// 疗效为 ND
result = OverallAssessment.ND;
}
// else if (靶病灶评估为NE && 非靶病灶评估为iCR，iNN，NE或ND && 新病灶评估为ND或疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.NE))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iCR))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.iNN))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 NE
result = OverallAssessment.NE;
}
// else if (靶病灶评估为ND && 非靶病灶评估为NE && 新病灶评估为ND或疑似或NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
&& (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.NE))
) && (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.ND))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.Suspected))
|| inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
))
{
// 疗效为 NE
result = OverallAssessment.NE;
}
// else if (靶病灶评估为ND && 非靶病灶评估为ND && 新病灶评估为NE)
else if (inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.TargetLesion && x.Answer.EqEnum(TargetAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NoTargetLesion && x.Answer.EqEnum(NoTargetAssessment.ND))
&& inDto.QuestionInfo.Any(x => x.QuestionType == QuestionType.NewLesionEvaluation && x.Answer.EqEnum(NewLesionAssessment.NE))
)
{
// 疗效为 NE
result = OverallAssessment.NE;
}
else
{
//错误级别日志：项目、标准、受试者、阅片人、任务。输出靶病灶、非靶病灶、新病灶的评估结果：
// 这里是记录日志 不需要国际化
var criterionInfo = await _readingQuestionCriterionTrialRepository.Where(x => x.Id == inDto.TrialReadingCriterionId).Include(x => x.Trial).FirstNotNullAsync();
var taskInfo = await _visitTaskRepository.Where(x => x.Id == inDto.VisitTaskId).Include(x => x.Subject).Include(x => x.DoctorUser).FirstNotNullAsync();
StringBuilder builder = new StringBuilder();
builder.AppendLine($"");
builder.AppendLine($"【项目】:【{criterionInfo.Trial.TrialCode}】");
builder.AppendLine($"【项目Id】:【{criterionInfo.TrialId}】");
builder.AppendLine($"【标准】:【{criterionInfo.CriterionName}】");
builder.AppendLine($"【标准Id】:【{criterionInfo.Id}】");
builder.AppendLine($"【受试者】:【{taskInfo.Subject.ShortName}】");
builder.AppendLine($"【受试者Id】:【{taskInfo.Subject.Id}】");
builder.AppendLine($"【阅片人】:【{taskInfo.DoctorUser.FullName}】");
builder.AppendLine($"【阅片人Id】:【{taskInfo.DoctorUser.Id}】");
builder.AppendLine($"【任务】:【{taskInfo.TaskBlindName}】");
builder.AppendLine($"【任务Id】:【{taskInfo.Id}】");
builder.AppendLine($"【病灶类型】:【新病灶】");
builder.AppendLine($"【靶病灶评估】:【{inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.TargetLesion).Select(x => x.Answer).FirstIsNullReturnEmpty()}】");
builder.AppendLine($"【非靶病灶评估】:【{inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NoTargetLesion).Select(x => x.Answer).FirstIsNullReturnEmpty()}】");
builder.AppendLine($"【新病灶评估】:【{inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.NewLesionEvaluation).Select(x => x.Answer).FirstIsNullReturnEmpty()}】");
_logger.LogError(builder.ToString());
}
return result == null ? string.Empty : ((OverallAssessment)result).GetEnumInt();
}
#endregion
#endregion
#region 转化时计算
#region 获取转化的靶病灶评估
/// <summary>
/// 获取转化的靶病灶评估
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetConvertingTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var beforeConvertedAnswer = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.BeforeConvertedTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.TargetLesion).Select(x => x.Answer).FirstOrDefaultAsync();
Dictionary<string, string> answerConverDic = new Dictionary<string, string>()
{
{TargetAssessment.SD.GetEnumInt(),TargetAssessment.iSD.GetEnumInt() },
{TargetAssessment.PR.GetEnumInt(),TargetAssessment.iPR.GetEnumInt() },
{TargetAssessment.PD.GetEnumInt(),TargetAssessment.iUPD.GetEnumInt() },
{TargetAssessment.CR.GetEnumInt(), TargetAssessment.iCR.GetEnumInt() },
};
try
{
return answerConverDic[beforeConvertedAnswer];
}
catch (Exception)
{
return beforeConvertedAnswer == null ? string.Empty : beforeConvertedAnswer;
}
}
#endregion
#region 获取转化的非靶病灶评估
/// <summary>
/// 获取转化的非靶病灶评估
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetConvertingNoTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var beforeConvertedAnswer = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.BeforeConvertedTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.NoTargetLesion).Select(x => x.Answer).FirstOrDefaultAsync();
Dictionary<string, string> answerConverDic = new Dictionary<string, string>()
{
{NoTargetAssessment.NN.GetEnumInt(),NoTargetAssessment.iNN.GetEnumInt() },
{NoTargetAssessment.PD.GetEnumInt(),NoTargetAssessment.iUPD.GetEnumInt() },
{NoTargetAssessment.CR.GetEnumInt(), NoTargetAssessment.iCR.GetEnumInt() },
};
try
{
return answerConverDic[beforeConvertedAnswer];
}
catch (Exception)
{
return beforeConvertedAnswer == null ? string.Empty : beforeConvertedAnswer;
}
}
#endregion
#region 获取转化的整体肿瘤评估
/// <summary>
/// 获取转化的整体肿瘤评估
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetConvertingTumor(ReadingCalculateDto inDto)
{
var beforeConvertedAnswer = await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == inDto.BeforeConvertedTaskId && x.ReadingQuestionTrial.QuestionType == QuestionType.Tumor).Select(x => x.Answer).FirstOrDefaultAsync();
Dictionary<string, string> answerConverDic = new Dictionary<string, string>()
{
{OverallAssessment.NN.GetEnumInt(),OverallAssessment.iNN.GetEnumInt() },
{OverallAssessment.PD.GetEnumInt(),OverallAssessment.iUPD.GetEnumInt() },
{OverallAssessment.CR.GetEnumInt(), OverallAssessment.iCR.GetEnumInt() },
{OverallAssessment.SD.GetEnumInt(), OverallAssessment.iSD.GetEnumInt() },
{OverallAssessment.PR.GetEnumInt(), OverallAssessment.iPR.GetEnumInt() },
};
try
{
return answerConverDic[beforeConvertedAnswer];
}
catch (Exception)
{
return beforeConvertedAnswer == null ? string.Empty : beforeConvertedAnswer;
}
}
#endregion
#endregion
#region 获取靶病灶评估
/// <summary>
/// 获取靶病灶评估
/// </summary>
/// <param name="inDto"></param>
/// <remarks>
/// 靶病灶疗效评估算法-20230306确认版本：
///if（基线没有靶病灶）
///{
/// 靶病灶疗效为 ND
///}else
///{
/// 初始化靶病灶疗效为 SD
///
/// if (与基线期SOD相比减小≥30 %）
/// {
/// 靶病灶疗效为 PR
///
/// }
///
///if (非淋巴结靶病灶长径之和 == 0 并且所有淋巴结靶病灶的短径 < 10且淋巴结非靶病灶全部消失)
/// {
/// 靶病灶疗效为 CR
///
/// }
///
///if （有被评估为NE的单个靶病灶）
/// {
/// 靶病灶疗效为 NE
///
/// }
///
///if (最低点SOD > 0)
///{
/// if（比整体访视期间最低点SOD增加≥20 % 且与整个访视期间最低点相比增加的值≥5 mm）
/// {
/// 靶病灶疗效为 PD
///
/// }
///}
///else
///{
/// //进入该分支最低点SOD=0
/// if (当前访视SOD > 0 且与整个访视期间最低点相比增加的值≥5 mm)
/// {
/// 靶病灶疗效为PD
///
/// }
///}
///
///if（上次访视点评估是CR）
/// {
/// if (当前访视点淋巴结病灶,至少一个淋巴结靶病灶短径≥10 mm 并且该淋巴结靶病灶短径绝对增加值≥5 mm)
/// {
/// 靶病灶疗效为 PD
///
/// }
/// if (当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径＞0 mm。)
/// {
/// 靶病灶疗效为 PD
///
/// }
///}
///}
/// </remarks>
/// <returns></returns>
public async Task<string> GetTargetLesionEvaluate(ReadingCalculateDto inDto)
{
var tableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.TargetLesion).SelectMany(x => x.TableRowInfoList).ToList();
if (inDto.IsBaseLine)
{
return TargetAssessment.NA.GetEnumInt();
}
TargetLesionCalculateDto resultData = new TargetLesionCalculateDto()
{
// 是否存在靶病灶
ExistsTargetLesion = tableQuestion.Count() > 0,
// 最低SOD
LowSod = (await GetLowSODVisit(inDto)).Select(x => x.SOD).FirstOrDefault(),
// 当前Sod
PresentSod = (await GetSODData(inDto)) ?? 0,
//非淋巴结靶病灶长径之和 decimal
SumOfDiameter = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SumOfDiameter).Sum(x => x.Answer.IsNullOrEmptyReturn0()),
//所有淋巴结靶病灶的短径小于10mm bool
DiameterLessThan10 = true,
// SOD变化百分比
SODPercent = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()),
// SOD 百分比与基线期SOD相比减小≥30% bool
SODPercentBigger30 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) <= -30,
// SOD 百分比 与基线期SOD相比减小＜30% bool
SODPercentLess30 = 0 > inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) &&
inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.SODPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) > -30,
// SOD 百分比 整体访视期间SOD最低点SOD相比增加＜20%
LowSODPercentLess20 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) < 20,
// SOD 百分比 比整体访视期间SOD最低点SOD增加≥20%
LowSODPercentBigger20 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowPercent).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 20,
// SOD 变化值 比整体访视期间SOD最低点SOD绝对增加值＜5 mm
LowSODChangeLess5 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowestIncrease).Sum(x => x.Answer.IsNullOrEmptyReturn0()) < 5,
// 比整体访视期间SOD最低点SOD绝对增加值≥5 mm
LowSODChangeBigger5 = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.LowestIncrease).Sum(x => x.Answer.IsNullOrEmptyReturn0()) >= 5,
// 被评估为NE的单个靶病灶 是否存在状态为不可评估的靶病灶
ExixtsNETargetLesion = tableQuestion.SelectMany(x => x.TableQuestionList).Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(TargetState.UnableEvaluate)),
//// 上次访视点整体肿瘤评估
LastTargetLesionEvaluate = string.Empty,
// 当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径＞0 mm
CurrentMajoreBigger0 = false,
// 当前访视点淋巴结病灶, 至少一个淋巴结靶病灶短径≥10 mm
CurrenShortBigger10 = false,
// 靶病灶短径增加值有5mm的Index
AddFiveIndexs = await GetIsAddFiveRowIndexs(inDto),
// 短径有10mm的Index
ShortBigger10Indexs = new List<decimal>(),
//淋巴结非靶病灶状态全部为消失
NonTargetStateIsLoss = true,
// 该淋巴结靶病灶短径绝对增加值≥5 mm
IsAddFive = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.IsAddFive && x.Answer.EqEnum(YesOrNoOrNa.Yes)).Count() > 0,
};
var nonTargetTableQuestion = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList).ToList();
foreach (var item in nonTargetTableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
// 淋巴结非靶病灶状态全部为消失
resultData.NonTargetStateIsLoss = resultData.NonTargetStateIsLoss && item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.State).Select(x => x.Answer).FirstOrDefault() == NoTargetState.Loss.GetEnumInt();
}
}
foreach (var item in tableQuestion)
{
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
// 淋巴结的短径
resultData.DiameterLessThan10 = resultData.DiameterLessThan10 && (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() < 10;
var shortIsBigger10 = (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.ShortAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() >= 10;
resultData.CurrenShortBigger10 = resultData.CurrenShortBigger10 || shortIsBigger10;
if (shortIsBigger10)
{
resultData.ShortBigger10Indexs.Add(item.RowIndex);
}
}
if (item.TableQuestionList.Any(x => x.QuestionMark == QuestionMark.IsLymph && !x.Answer.EqEnum(YesOrNoOrNa.Yes)))
{
// 当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径
resultData.CurrentMajoreBigger0 = resultData.CurrentMajoreBigger0 || (item.TableQuestionList.Where(x => x.QuestionMark == QuestionMark.MajorAxis).Select(x => x.Answer).FirstOrDefault()).IsNullOrEmptyReturn0() > 0;
}
}
var lastVisitTaskId = await GetLastVisitTaskId(inDto);
var questionId = inDto.QuestionInfo.Where(x => x.QuestionType == QuestionType.Tumor).Select(x => x.QuestionId).FirstOrDefault();
resultData.LastTargetLesionEvaluate = (await _readingTaskQuestionAnswerRepository.Where(x => x.VisitTaskId == lastVisitTaskId && x.ReadingQuestionTrialId == questionId)
.Select(x => x.Answer).FirstOrDefaultAsync()) ?? string.Empty;
TargetAssessment result = TargetAssessment.SD;
//if（基线没有靶病灶）
if (!resultData.ExistsTargetLesion)
{
// 靶病灶疗效为 ND
result = TargetAssessment.ND;
}
else
{
//初始化靶病灶疗效为 SD
result = TargetAssessment.SD;
//if (与基线期SOD相比减小≥30 %）
if (resultData.SODPercentBigger30)
{
//靶病灶疗效为 PR
result = TargetAssessment.PR;
}
//if (非淋巴结靶病灶长径之和 == 0 并且所有淋巴结靶病灶的短径 < 10且淋巴结非靶病灶全部消失)
if (resultData.SumOfDiameter == 0 && resultData.DiameterLessThan10 && resultData.NonTargetStateIsLoss)
{
//靶病灶疗效为 CR
result = TargetAssessment.CR;
}
// if （有被评估为NE的单个靶病灶）
if (resultData.ExixtsNETargetLesion)
{
// 靶病灶疗效为 NE
result = TargetAssessment.NE;
}
//if (最低点SOD > 0)
if (resultData.LowSod > 0)
{
// if（比整体访视期间最低点SOD增加≥20 % 且与整个访视期间最低点相比增加的值≥5 mm）
if (resultData.LowSODPercentBigger20 && resultData.LowSODChangeBigger5)
{
// 靶病灶疗效为 PD
result = TargetAssessment.PD;
}
}
else
{
//进入该分支最低点SOD=0
// if (当前访视SOD > 0 且与整个访视期间最低点相比增加的值≥5 mm)
if (resultData.PresentSod > 0 && resultData.LowSODChangeBigger5)
{
// 靶病灶疗效为PD
result = TargetAssessment.PD;
}
}
//if（上次访视点评估是CR）
if (resultData.LastTargetLesionEvaluate.EqEnum(OverallAssessment.CR))
{
//if (当前访视点淋巴结病灶,至少一个淋巴结靶病灶短径≥10 mm 并且该淋巴结靶病灶短径绝对增加值≥5 mm)
// 换句话说 就是 短径≥10 的病灶 和 短径增加值≥5的病灶 的交集数量大于0
if (resultData.ShortBigger10Indexs.Intersect(resultData.AddFiveIndexs).ToList().Count() > 0)
{
//靶病灶疗效为 PD
result = TargetAssessment.PD;
}
//if (当前访视点非淋巴结病灶至少一个非淋巴结靶病灶的长径＞0 mm。)
if (resultData.CurrentMajoreBigger0)
{
//靶病灶疗效为 PD
result = TargetAssessment.PD;
}
}
#region 之前的逻辑 备注
//if (resultData.LastTargetLesionEvaluate.EqEnum(TargetAssessment.CR))
//{
// if (resultData.ExixtsNETargetLesion)
// {
// result = TargetAssessment.NE;
// }
// if (resultData.CurrenShortBigger10 && resultData.IsAddFive)
// {
// result = TargetAssessment.PD;
// }
// if (resultData.CurrentMajoreBigger0)
// {
// result = TargetAssessment.PD;
// }
//}
//else
//{
// if (resultData.LowSod != 0 && resultData.LowPercentBigger20 && resultData.LowChangeBigger5)
// {
// result = TargetAssessment.PD;
// }
// else
// {
// if (resultData.ExixtsNETargetLesion)
// {
// result = TargetAssessment.NE;
// }
// else
// {
// if (resultData.SODPercentBigger30)
// {
// if (resultData.LowPercentLess20 || resultData.LowChangeLess5)
// {
// result = TargetAssessment.PR;
// }
// if (resultData.SumOfDiameter == 0 && resultData.DiameterLessThan10 && resultData.NonTargetStateIsLoss)
// {
// result = TargetAssessment.CR;
// }
// }
// }
// }
//}
#endregion
}
return result.GetEnumInt();
}
#endregion
#region 获取非靶病灶评估
/// <summary>
/// 获取非靶病灶评估
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNoTargetLesionEvaluate(ReadingCalculateDto inDto)
{
NoTargetAssessment result = NoTargetAssessment.NN;
if (inDto.IsBaseLine)
{
return NoTargetAssessment.NA.GetEnumInt();
}
var tableRows = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NonTargetLesions).SelectMany(x => x.TableRowInfoList).ToList();
var tableQuestions = tableRows.SelectMany(x => x.TableQuestionList).ToList();
//任意单个病灶 / 病灶组评估为“显著增大”
if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && (x.Answer.EqEnum(NoTargetState.Increase) || x.Answer.EqEnum(NoTargetState.IUPD))))
{
result = NoTargetAssessment.PD;
}
// 任意单个病灶/病灶组评估为“无法评估”并且没有“显著增大”
else if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.UnableEvaluate)) &&
!tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Increase))
)
{
result = NoTargetAssessment.NE;
}
// 所有单个病灶/病灶组评估为”存在”或者有些评估为“消失”有些评估为“存在”,且没有“显著增大”和“无法评估”的病灶
else if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Exist))
&& !tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && (x.Answer.EqEnum(NoTargetState.Increase) || x.Answer.EqEnum(NoTargetState.UnableEvaluate)))
)
{
result = NoTargetAssessment.NN;
}
//所有单个病灶/病灶组状态评估状态为“消失”
else if (tableQuestions.Count(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NoTargetState.Loss)) == tableQuestions.Count(x => x.QuestionMark == QuestionMark.State) && tableQuestions.Count(x => x.QuestionMark == QuestionMark.State) > 0)
{
result = NoTargetAssessment.CR;
}
// 基线时没有非靶病灶
else if (tableQuestions.Count() == 0)
{
result = NoTargetAssessment.ND;
}
else
{
return string.Empty;
}
return result.GetEnumInt();
}
#endregion
#region 获取新病灶评估
/// <summary>
/// 获取新病灶评估
/// </summary>
/// <param name="inDto"></param>
/// <returns></returns>
public async Task<string> GetNewLesionEvaluate(ReadingCalculateDto inDto)
{
NewLesionAssessment result = NewLesionAssessment.No;
if (inDto.IsBaseLine)
{
return NewLesionAssessment.NA.GetEnumInt();
}
var tableRows = inDto.QuestionInfo.Where(x => x.LesionType == LesionType.NewLesions).SelectMany(x => x.TableRowInfoList).ToList();
var tableQuestions = tableRows.SelectMany(x => x.TableQuestionList).ToList();
// 当前访视存在至少一个明确新病灶
if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.Exist)))
{
result = NewLesionAssessment.Yes;
}
//只要有任何一个新病灶状态为“无法评估”
else if (tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.UnableEvaluate)))
{
result = NewLesionAssessment.NE;
}
//当前访视不存在明确新病灶且存在至少一个疑似新病灶
else if (!tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.Exist)) &&
tableQuestions.Any(x => x.QuestionMark == QuestionMark.State && x.Answer.EqEnum(NewLesionState.Suspected))
)
{
result = NewLesionAssessment.Suspected;
}
else
{
result = NewLesionAssessment.No;
}
return result.GetEnumInt();
}
#endregion
#endregion
}
}