//--------------------------------------------------------------------
//     此代码由T4模板自动生成  byzhouhang 20210918
//	   生成时间 2023-06-15 15:06:06 
//     对此文件的更改可能会导致不正确的行为，并且如果重新生成代码，这些更改将会丢失。
//--------------------------------------------------------------------

using IRaCIS.Core.Application.Contracts;
using IRaCIS.Core.Application.Interfaces;
using IRaCIS.Core.Application.Service.Reading.Dto;
using IRaCIS.Core.Application.Service.Reading.Interface;
using IRaCIS.Core.Domain.Share;
using IRaCIS.Core.Infra.EFCore.Common;
using IRaCIS.Core.Infrastructure;
using MassTransit;
using Microsoft.AspNetCore.Mvc;

namespace IRaCIS.Core.Application.Service
{
    /// <summary>
    /// 临床答案
    /// </summary>	
    [ApiExplorerSettings(GroupName = "Reading")]
    public class ClinicalAnswerService(
        IRepository<TrialClinicalQuestion> _trialClinicalQuestionRepository,
        IRepository<TrialClinicalTableQuestion> _trialClinicalTableQuestionRepository,
        IRepository<ClinicalDataTrialSet> _clinicalDataTrialSetRepository,
        IRepository<ClinicalForm> _clinicalFormRepository,
        IRepository<Subject> _subjectRepository,
        IRepository<ReadModuleCriterionFrom> _readModuleCriterionFromRepository,
        IRepository<ReadModule> _readModuleRepository,
        IRepository<DicomStudy> _dicomStudyRepository,
        IRepository<ClinicalQuestionAnswer> _clinicalQuestionAnswerRepository,
        IRepository<ClinicalTableAnswer> _clinicalTableAnswerRepository,
        IRepository<ClinicalAnswerRowInfo> _clinicalAnswerRowInfoRepository,
        IRepository<ReadingClinicalData> _readingClinicalDataRepository,
        IRepository<SubjectVisit> _subjectVisitRepository,
        IClinicalQuestionService _iClinicalQuestionService,
        IReadingClinicalDataService _iReadingClinicalDataService) : BaseService, IClinicalAnswerService
    {


        /// <summary>
        /// CRC签名临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<IResponseOutput> CRCSignClinicalData(CRCSignClinicalDataInDto inDto)
        {

            await _readingClinicalDataRepository.UpdatePartialFromQueryAsync(x => x.Id == inDto.ReadingClinicalDataId, x => new ReadingClinicalData()
            {
                IsSign = true,
                ReadingClinicalDataState = ReadingClinicalDataStatus.HaveSigned
            });

            await _readingClinicalDataRepository.SaveChangesAsync();
            return ResponseOutput.Ok(true);
        }

        /// <summary>
        /// 删除检查级别临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        public async Task DeleteStudyClinical(DeleteStudyClinicalInDto inDto)
        {
            await _readingClinicalDataRepository.BatchDeleteNoTrackingAsync(x => x.StudyId == inDto.StudyId);

        }

        /// <summary>
        ///  添加检查级别临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        public async Task AddStudyClinical(AddStudyClinicalInDto inDto)
        {
            var studyInfo = await _dicomStudyRepository.Where(x => x.Id == inDto.StudyId).FirstNotNullAsync();

            List<ClinicalDataTrialSet> clinicals = await _clinicalDataTrialSetRepository.Where(x =>
            x.TrialId == studyInfo.TrialId && x.IsConfirm && x.ClinicalDataLevel == ClinicalLevel.Study).ToListAsync();

            List<ReadingClinicalData> datas = new List<ReadingClinicalData>();

            clinicals.ForEach(x =>
            {
                datas.Add(new ReadingClinicalData()
                {
                    ClinicalDataTrialSetId = x.Id,
                    IsVisit = true,
                    SubjectId = studyInfo.SubjectId,
                    ReadingId = studyInfo.SubjectVisitId,
                    TrialId = studyInfo.TrialId,
                    StudyId = studyInfo.Id

                });

            });

            await _readingClinicalDataRepository.AddRangeAsync(datas);
            await _readingClinicalDataRepository.SaveChangesAsync();

        }

        /// <summary>
        /// 自动添加CRC临床数据 (不包括检查级别)
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        public async Task AutoAddCRCClinical(AutoAddClinicalInDto inDto)
        {
            var dataTrialSetList = await _clinicalDataTrialSetRepository.Where(x => x.TrialId == inDto.TrialId && x.UploadRole == UploadRole.CRC && x.IsConfirm)
              .IgnoreAutoIncludes().ToListAsync();
            var baseLine = await _subjectVisitRepository.Where(x => x.TrialId == inDto.TrialId)
                .WhereIf(inDto.SubjectId != null, x => x.SubjectId == inDto.SubjectId)

                .Select(x => new
                {

                    x.SubjectId,
                    VisitId = x.Id,
                    x.IsBaseLine,
                }).ToListAsync();

            var clinicalDataList = await _readingClinicalDataRepository
                   .WhereIf(inDto.SubjectId != null, x => x.SubjectId == inDto.SubjectId)
                .Where(x => x.TrialId == inDto.TrialId && x.ClinicalDataTrialSet.UploadRole == UploadRole.CRC)
                .Select(x => new
                {
                    ClinicalDataTrialSetId = x.ClinicalDataTrialSetId,
                    SubjectId = x.SubjectId,
                    x.ReadingId,

                }).ToListAsync();

            List<ReadingClinicalData> readingClinicalDatas = new List<ReadingClinicalData>();

            baseLine.Select(x => x.SubjectId).Distinct().ForEach(n =>
            {
                var baseLineVisitId = baseLine.Where(x => x.IsBaseLine && x.SubjectId == n).Select(x => x.VisitId).First();
                readingClinicalDatas.AddRange(
                    dataTrialSetList.Where(x => x.ClinicalDataLevel == ClinicalLevel.Subject).Where(x => clinicalDataList.Where(y => y.ClinicalDataTrialSetId == x.Id && y.SubjectId == n).Count() == 0)
                    .Select(x => new ReadingClinicalData()
                    {
                        ClinicalDataTrialSetId = x.Id,
                        IsVisit = true,
                        SubjectId = n,
                        ReadingId = baseLineVisitId,
                        TrialId = inDto.TrialId
                    }).ToList());


                readingClinicalDatas.AddRange(
                  dataTrialSetList.Where(x => x.ClinicalDataLevel == ClinicalLevel.ImageRead).Where(x => clinicalDataList.Where(y => y.ClinicalDataTrialSetId == x.Id && y.SubjectId == n).Count() == 0)
                  .Select(x => new ReadingClinicalData()
                  {
                      ClinicalDataTrialSetId = x.Id,
                      IsVisit = false,
                      SubjectId = n,
                      ReadingId = default(Guid),
                      TrialId = inDto.TrialId
                  }).ToList());

                readingClinicalDatas.AddRange(
                  dataTrialSetList.Where(x => x.ClinicalDataLevel == ClinicalLevel.OncologyRead).Where(x => clinicalDataList.Where(y => y.ClinicalDataTrialSetId == x.Id && y.SubjectId == n).Count() == 0)
                  .Select(x => new ReadingClinicalData()
                  {
                      ClinicalDataTrialSetId = x.Id,
                      IsVisit = false,
                      SubjectId = n,
                      ReadingId = default(Guid),
                      TrialId = inDto.TrialId
                  }).ToList());
            });

            baseLine.ForEach(n =>
            {
                readingClinicalDatas.AddRange(
                   dataTrialSetList.Where(x => x.ClinicalDataLevel == ClinicalLevel.SubjectVisit).Where(x => clinicalDataList.Where(y => y.ClinicalDataTrialSetId == x.Id && y.ReadingId == n.VisitId).Count() == 0)
                   .Select(x => new ReadingClinicalData()
                   {
                       ClinicalDataTrialSetId = x.Id,
                       IsVisit = true,
                       SubjectId = n.SubjectId,
                       ReadingId = n.VisitId,
                       TrialId = inDto.TrialId
                   }).ToList());

                //readingClinicalDatas.AddRange(
                //   dataTrialSetList.Where(x => x.ClinicalDataLevel == ClinicalLevel.Study).Where(x => clinicalDataList.Where(y => y.ClinicalDataTrialSetId == x.Id && y.ReadingId == n.VisitId).Count() == 0)
                //   .Select(x => new ReadingClinicalData()
                //   {
                //	   ClinicalDataTrialSetId = x.Id,
                //	   IsVisit = true,
                //	   SubjectId = n.SubjectId,
                //	   ReadingId = n.VisitId,
                //	   TrialId = inDto.TrialId
                //   }).ToList());
            });


            await _readingClinicalDataRepository.AddRangeAsync(readingClinicalDatas);
            await _readingClinicalDataRepository.SaveChangesAsync();


        }

        /// <summary>
        /// 获取CRC受试者临床数据
        /// </summary>
        /// <param name="inQuery"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<PageOutput<GetCRCSubjectClinicalOutDto>> GetCRCSubjectClinicalList(GetCRCSubjectClinicalInDto inQuery)
        {

            //await AutoAddCRCClinical(new AutoAddClinicalInDto()
            //{
            //    TrialId = inDto.TrialId
            //}) ;

            var subjects = await _subjectRepository.Where(x => x.TrialId == inQuery.TrialId).Select(x => new GetCRCSubjectClinicalResultDto()
            {
                SubjectId = x.Id,
                SubjectCode = x.Code
            }).ToListAsync();


            var clinicalData = _readingClinicalDataRepository.Where(x => x.TrialId == inQuery.TrialId && x.ClinicalDataTrialSet.UploadRole == UploadRole.CRC && x.ClinicalDataTrialSet.ClinicalDataLevel != ClinicalLevel.SubjectVisit)
                .Where(x => !x.IsSign)
                .WhereIf(inQuery.SubjectId != null, x => x.SubjectId == inQuery.SubjectId)
                .WhereIf(inQuery.SubjectCode != null, x => x.Subject.Code.Contains(inQuery.SubjectCode ?? string.Empty))
                .Where(x => x.ClinicalDataTrialSet.ClinicalDataLevel != ClinicalLevel.Subject)
                .Include(x => x.ClinicalDataTrialSet).Select(x => new GetCRCSubjectClinicalOutDto()
                {
                    SubjectId = x.SubjectId,
                    SubjectCode = x.Subject.Code,
                    TrialId = inQuery.TrialId,
                    ReadingId = x.ReadingId,
                    ReadingClinicalDataId = x.Id,
                    UploadRole = x.ClinicalDataTrialSet.UploadRole,
                    ClinicalDataLevel = x.ClinicalDataTrialSet.ClinicalDataLevel,
                    ClinicalUploadType = x.ClinicalDataTrialSet.ClinicalUploadType,
                    BaseLineVisitId = x.Subject.SubjectVisitList.Where(x => x.IsBaseLine).Select(x => x.Id).FirstOrDefault(),
                    ClinicalDataTrialSetId = x.ClinicalDataTrialSet.Id,
                    ClinicalDataSetEnName = x.ClinicalDataTrialSet.ClinicalDataSetEnName,
                    ClinicalDataSetName = x.ClinicalDataTrialSet.ClinicalDataSetName,
                });

            var pageList = await clinicalData.ToPagedListAsync(inQuery, nameof(GetCRCSubjectClinicalOutDto.SubjectCode));
            // 一次查询报错 分两次写
            pageList.CurrentPageData.ForEach(x =>
            {
                x.ClinicalDataSetEnName = x.ClinicalDataSetName.LanguageName(x.ClinicalDataSetEnName, _userInfo.IsEn_Us);
            });
            var clinicalFormData = await _clinicalFormRepository.Where(x => x.TrialId == inQuery.TrialId).ToListAsync();
            pageList.CurrentPageData.ForEach(n =>
            {
                n.ClinicalCount = clinicalFormData.Where(y => y.ClinicalDataTrialSetId == n.ClinicalDataTrialSetId && y.SubjectId == n.SubjectId).Count();
            });
            return pageList;
        }

        /// <summary>
        /// 获取表单列表
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<GetClinicalQuestionAnswerListOutDto> GetClinicalQuestionFormList(GetClinicalQuestionAnswerListInDto inDto)
        {
            var result = new GetClinicalQuestionAnswerListOutDto();
            result.AnswerList = new List<Dictionary<string, string>>();
            result.QuestionList = await _trialClinicalQuestionRepository.Where(x => x.TrialClinicalId == inDto.ClinicalDataTrialSetId
            && x.ClinicalQuestionType != ReadingQestionType.Group
            && x.ClinicalQuestionType != ReadingQestionType.Table
              && x.ClinicalQuestionType != ReadingQestionType.BasicTable
            ).OrderByDescending(x => x.IsCheckDate).ThenBy(x => x.ShowOrder)
               .ProjectTo<TrialClinicalQuestionDto>(_mapper.ConfigurationProvider).ToListAsync();
            if (_userInfo.IsEn_Us)
            {
                result.QuestionList.ForEach(x =>
                {
                    x.GroupName = x.GroupEnName;
                    x.QuestionName = x.QuestionEnName;
                });
            }

            var answers = await _clinicalQuestionAnswerRepository.Where(x => x.SubjectId == inDto.SubjectId && x.ClinicalDataTrialSetId == inDto.ClinicalDataTrialSetId)
                .Select(x => new
                {
                    x.ClinicalFormId,
                    x.ClinicalForm.CheckDate,
                    x.QuestionId,
                    x.Answer
                })
                .ToListAsync();

            var ClinicalFormIds = answers.OrderBy(x => x.CheckDate).Select(x => x.ClinicalFormId).Distinct().ToList();
            ClinicalFormIds.ForEach(x =>
            {
                var dic = answers.Where(y => y.ClinicalFormId == x).ToDictionary(x => x.QuestionId.ToString(), x => x.Answer);
                dic.Add("ClinicalFormId", x.ToString());
                dic.Add("TrialId", inDto.TrialId.ToString());
                dic.Add("SubjectId", inDto.SubjectId.ToString());
                dic.Add("ClinicalDataTrialSetId", inDto.ClinicalDataTrialSetId.ToString());

                result.AnswerList.Add(dic);

            });
            return result;
        }

        /// <summary>
        /// 获取临床数据表单问题
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<List<ClinicalQuestionPreviewDto>> GetClinicalFormInfo(GetClinicalFormInfoInDto inDto)
        {
            var formInfo = await _clinicalFormRepository.Where(x => x.Id == inDto.ClinicalFormId).FirstNotNullAsync();

            var questionAnswer = await _clinicalQuestionAnswerRepository.Where(x => x.ClinicalFormId == inDto.ClinicalFormId).Select(x => new ClinicalFormQuestionAnswer
            {
                QuestionId = x.QuestionId,
                Answer = x.Answer
            }).ToListAsync();

            var tableAnswer = await _clinicalTableAnswerRepository.Where(x => x.ClinicalFormId == inDto.ClinicalFormId).Select(x => new ClinicalFormTableQuestionAnswer
            {
                TableQuestionId = x.TableQuestionId,
                Answer = x.Answer,
                QuestionId = x.QuestionId,
                RowIndex = x.ClinicalAnswerRowInfo.RowIndex
            }).ToListAsync();

            var questions = await _trialClinicalQuestionRepository.Where(x => x.TrialClinicalId == formInfo.ClinicalDataTrialSetId)
              .ProjectTo<ClinicalQuestionPreviewDto>(_mapper.ConfigurationProvider).ToListAsync();

            var tableQuestions = await _trialClinicalTableQuestionRepository.Where(x => x.TrialClinicalId == formInfo.ClinicalDataTrialSetId)
                .ProjectTo<ClinicalTablePreviewDto>(_mapper.ConfigurationProvider).ToListAsync();

            questions.ForEach(x => x.CreateTime = formInfo.CreateTime);
            var result = questions.Where(x => x.ClinicalQuestionType == ReadingQestionType.Group).ToList();

            result.ForEach(x =>
            {
                _iClinicalQuestionService.FindChildQuestion(x, questions, tableQuestions, questionAnswer, tableAnswer);
            });

            return result;
        }



        /// <summary>
        /// 提交临床数据表单
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<IResponseOutput> SubmitClinicalForm(SubmitClinicalFormInDto inDto)
        {



            ClinicalForm clinicalForm = new ClinicalForm() { };
            clinicalForm = new ClinicalForm()
            {
                ClinicalDataTrialSetId = inDto.ClinicalDataTrialSetId,
                SubjectId = inDto.SubjectId,
                PicturePath = inDto.PicturePath,
                TrialId = inDto.TrialId,
                Id = inDto.ClinicalFormId ?? NewId.NextGuid(),
                ReadingId = inDto.ReadingId,
            };

            if (inDto.ClinicalFormId != null && (await _readModuleCriterionFromRepository.AnyAsync(x => x.ClinicalFormId == inDto.ClinicalFormId.Value)))
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_translation"]);
            }

            var existsClinical = await _clinicalFormRepository.Where(x =>
            x.SubjectId == inDto.SubjectId
            && x.ClinicalDataTrialSetId == inDto.ClinicalDataTrialSetId
            ).WhereIf(inDto.ReadingId != null, x => x.ReadingId == inDto.ReadingId)
            .Where(x => x.ClinicalDataTrialSet.UploadRole != UploadRole.CRC && !(x.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.ImageRead
            || x.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.OncologyRead)).AnyAsync();

            if (existsClinical)
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_duplicateData"]);
            }
            try
            {
                var checkDateQuestionId = await _trialClinicalQuestionRepository.Where(x => x.TrialClinicalId == inDto.ClinicalDataTrialSetId && x.IsCheckDate).Select(x => x.Id).FirstNotNullAsync();
                clinicalForm.CheckDate = DateTime.Parse(inDto.QuestionAnswers.Where(x => x.QuestionId == checkDateQuestionId).Select(x => x.Answer).First());

            }
            catch (Exception)
            {

            }

            if (clinicalForm.CheckDate != null)
            {
                if (await _readModuleRepository.AnyAsync(x => x.SubjectId == inDto.SubjectId && x.SubjectVisit.LatestScanDate <= clinicalForm.CheckDate && x.IsCRCConfirm))
                {
                    throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_unableToAddOrUpdate", clinicalForm.CheckDate.Value.ToString("yyyy-MM-dd")]);
                }

            }

            List<ClinicalQuestionAnswer> clinicalQuestionAnswers = inDto.QuestionAnswers.Select(x => new ClinicalQuestionAnswer()
            {
                Answer = x.Answer,
                ClinicalDataTrialSetId = inDto.ClinicalDataTrialSetId,
                SubjectId = inDto.SubjectId,
                ClinicalFormId = clinicalForm.Id,
                QuestionId = x.QuestionId,
            }).ToList();

            List<ClinicalAnswerRowInfo> clinicalAnswerRowInfos = new List<ClinicalAnswerRowInfo>();

            List<ClinicalTableAnswer> clinicalTableAnswers = new List<ClinicalTableAnswer>();

            inDto.TableQuestionAnswerList.ForEach(x =>
            {
                var questionid = x.QuestionId;

                for (int i = 0; i < x.TableQuestionAnswers.Count(); i++)
                {
                    var rowInfo = new ClinicalAnswerRowInfo()
                    {
                        Id = NewId.NextGuid(),
                        SubjectId = inDto.SubjectId,
                        ClinicalFormId = clinicalForm.Id,
                        QuestionId = questionid,
                        RowIndex = i + 1,
                    };
                    clinicalAnswerRowInfos.Add(rowInfo);

                    x.TableQuestionAnswers[i].ForEach(y =>
                    {

                        clinicalTableAnswers.Add(new ClinicalTableAnswer()
                        {
                            Answer = y.Answer,
                            ClinicalFormId = clinicalForm.Id,
                            QuestionId = questionid,
                            RowId = rowInfo.Id,
                            TableQuestionId = y.TableQuestionId,
                            SubjectId = inDto.SubjectId,


                        });

                    });
                }

            });

            if (inDto.ClinicalFormId != null)
            {
                await _clinicalFormRepository.BatchDeleteNoTrackingAsync(x => x.Id == inDto.ClinicalFormId);
                await _clinicalQuestionAnswerRepository.BatchDeleteNoTrackingAsync(x => x.ClinicalFormId == inDto.ClinicalFormId);
                await _clinicalAnswerRowInfoRepository.BatchDeleteNoTrackingAsync(x => x.ClinicalFormId == inDto.ClinicalFormId);
                await _clinicalTableAnswerRepository.BatchDeleteNoTrackingAsync(x => x.ClinicalFormId == inDto.ClinicalFormId);
            }
            //if(inDto.ReadingId!=null)
            //{
            //    await _readingClinicalDataRepository.UpdatePartialFromQueryAsync(x => x.ReadingId == inDto.ReadingId && x.ClinicalDataTrialSetId == inDto.ClinicalDataTrialSetId, x => new ReadingClinicalData()
            //    {
            //        IsSign = true
            //    });
            //}
            await _clinicalFormRepository.AddAsync(clinicalForm);
            await _clinicalQuestionAnswerRepository.AddRangeAsync(clinicalQuestionAnswers);
            await _clinicalAnswerRowInfoRepository.AddRangeAsync(clinicalAnswerRowInfos);
            await _clinicalTableAnswerRepository.AddRangeAsync(clinicalTableAnswers);
            await _clinicalTableAnswerRepository.SaveChangesAsync();
            return ResponseOutput.Ok(true);
        }

        /// <summary>
        /// 删除表单数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        /// <exception cref="BusinessValidationFailedException"></exception>
        [HttpPost]
        public async Task<IResponseOutput> DeleteClinicalForm(DeleteClinicalFormInDto inDto)
        {

            if (await _readModuleCriterionFromRepository.AnyAsync(x => x.ClinicalFormId == inDto.ClinicalFormId))
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_unableToDelete"]);
            }

            await _clinicalFormRepository.BatchDeleteNoTrackingAsync(x => x.Id == inDto.ClinicalFormId);
            await _clinicalQuestionAnswerRepository.BatchDeleteNoTrackingAsync(x => x.ClinicalFormId == inDto.ClinicalFormId);
            await _clinicalAnswerRowInfoRepository.BatchDeleteNoTrackingAsync(x => x.ClinicalFormId == inDto.ClinicalFormId);
            await _clinicalTableAnswerRepository.BatchDeleteNoTrackingAsync(x => x.ClinicalFormId == inDto.ClinicalFormId);
            return ResponseOutput.Ok(true);
        }

        /// <summary>
        /// 获取PM待确认列表
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<PageOutput<GetCRCConfirmListOutDto>> GetPMConfirmList(GetPMConfirmListInDto inDto)
        {
            return await GetCRCConfirmList(new GetCRCConfirmListInDto()
            {
                TrialId = inDto.TrialId,
                IsCRCConfirm = true,
                IsPMConfirm = false,
                PageIndex = inDto.PageIndex,
                PageSize = inDto.PageSize,
                Asc = inDto.Asc,
                SortField = inDto.SortField,
                TrialReadingCriterionId = inDto.TrialReadingCriterionId

            });
        }

        /// <summary>
        /// 获取CRC确认列表
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<PageOutput<GetCRCConfirmListOutDto>> GetCRCConfirmList(GetCRCConfirmListInDto inDto)
        {
            if (inDto.ReadModuleId != null)
            {
                var readModule = await _readModuleRepository.Where(x => x.Id == inDto.ReadModuleId).FirstNotNullAsync();
                inDto.TrialReadingCriterionId = readModule.TrialReadingCriterionId;
            }

            // 有全局就查全局 有肿瘤学就查肿瘤学

            var clinicalDataLevelList = await _clinicalDataTrialSetRepository.Where(x => x.TrialId == inDto.TrialId && x.IsConfirm && x.UploadRole == UploadRole.CRC && x.ClinicalUploadType == ClinicalUploadType.Structuring).Select(x => x.ClinicalDataLevel).Distinct().ToListAsync();

            var existsCRCStructuring = clinicalDataLevelList.Any(x => x == ClinicalLevel.OncologyRead || x == ClinicalLevel.ImageRead);


            ReadingSetType? readingSetType = null;
            if (clinicalDataLevelList.Contains(ClinicalLevel.ImageRead) && !clinicalDataLevelList.Contains(ClinicalLevel.OncologyRead))
            {
                readingSetType = ReadingSetType.ImageReading;
            }
            else if (clinicalDataLevelList.Contains(ClinicalLevel.OncologyRead) && !clinicalDataLevelList.Contains(ClinicalLevel.ImageRead))
            {
                readingSetType = ReadingSetType.TumorReading;
            }


            var query = _readModuleRepository.Where(x => x.TrialId == inDto.TrialId)
                .Where(x => existsCRCStructuring)
                .WhereIf(inDto.ReadModuleId == null, x => x.TrialReadingCriterion.IsConfirm)
                .WhereIf(inDto.ReadModuleId != null, x => x.Id == inDto.ReadModuleId)
                .WhereIf(inDto.IsCRCConfirm != null, x => x.IsCRCConfirm == inDto.IsCRCConfirm)
                 .WhereIf(inDto.IsPMConfirm != null, x => x.IsPMConfirm == inDto.IsPMConfirm)
                .WhereIf(inDto.SubjectCode != null, x => x.Subject.Code.Contains(inDto.SubjectCode ?? string.Empty))
                .WhereIf(inDto.TrialReadingCriterionId != null, x => x.TrialReadingCriterionId == inDto.TrialReadingCriterionId)
                .WhereIf(inDto.SubjectId != null, x => x.SubjectId == inDto.SubjectId)
                .WhereIf(inDto.StartTime != null, x => x.SubjectVisit.LatestScanDate >= inDto.StartTime)
                .WhereIf(inDto.EndTime != null, x => x.SubjectVisit.LatestScanDate <= inDto.EndTime)
                .WhereIf(readingSetType != null, x => x.ReadingSetType == readingSetType)
                .Select(x => new GetCRCConfirmListOutDto()
                {

                    SubjectId = x.SubjectId,
                    IsNotNeedPMConfirm = x.IsNotNeedPMConfirm,
                    IsCRCConfirm = x.IsCRCConfirm,
                    IsCRCApplicationRevoke = x.IsCRCApplicationRevoke,
                    VisitBlindName = x.SubjectVisit.BlindName,
                    LatestScanDate = x.SubjectVisit.LatestScanDate,
                    ReadingSetType = x.ReadingSetType,
                    IsPMConfirm = x.IsPMConfirm,
                    SubjectCode = x.Subject.Code,
                    ReadModuleId = x.Id,
                    ModuleName = x.ModuleName,
                });

            var defalutSortArray = new string[] { nameof(GetCRCConfirmListOutDto.SubjectCode) + " desc", nameof(GetCRCConfirmListOutDto.LatestScanDate) };

            var result = await query.ToPagedListAsync(inDto, defalutSortArray);

            var formList = await _clinicalFormRepository.Where(x => x.TrialId == inDto.TrialId)
                .Where(x => x.ClinicalDataTrialSet.UploadRole == UploadRole.CRC)
                .WhereIf(inDto.TrialReadingCriterionId != null, x => x.ClinicalDataTrialSet.TrialClinicalDataSetCriteriaList.Any(y => y.TrialReadingCriterionId == inDto.TrialReadingCriterionId))
                .Where(x => x.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.ImageRead || x.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.OncologyRead)
                .Include(x => x.ClinicalDataTrialSet)
                .Select(x => new CRCClinicalForm
                {
                    SubjectId = x.SubjectId,
                    CheckDate = x.CheckDate,
                    ClinicalDataLevel = x.ClinicalDataTrialSet.ClinicalDataLevel,
                    ClinicalFormId = x.Id,
                    ClinicalDataTrialSetId = x.ClinicalDataTrialSet.Id,
                    ClinicalDataSetName = x.ClinicalDataTrialSet.ClinicalDataSetName,
                    ClinicalDataSetEnName = x.ClinicalDataTrialSet.ClinicalDataSetEnName,
                    IsHaveTableQuestion = x.ClinicalDataTrialSet.TrialClinicalQuestionList.Any(y => y.ClinicalQuestionType == ReadingQestionType.Table || y.ClinicalQuestionType == ReadingQestionType.BasicTable),
                }).ToListAsync();
            var confirmList = await _readModuleCriterionFromRepository.Where(x => x.TrialId == inDto.TrialId
                && x.ClinicalForm.ClinicalDataTrialSet.UploadRole == UploadRole.CRC
                && (x.ClinicalForm.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.ImageRead || x.ClinicalForm.ClinicalDataTrialSet.ClinicalDataLevel == ClinicalLevel.OncologyRead))
                .Select(x => new GetCRCBeConfirm
                {
                    CheckDate = x.ClinicalForm.CheckDate ?? default(DateTime),
                    ClinicalDataSetName = x.ClinicalForm.ClinicalDataTrialSet.ClinicalDataSetName,
                    ClinicalDataSetEnName = x.ClinicalForm.ClinicalDataTrialSet.ClinicalDataSetEnName,
                    ClinicalFormId = x.ClinicalFormId,
                    ClinicalDataTrialSetId = x.ClinicalForm.ClinicalDataTrialSet.Id,
                    ReadModuleId = x.ReadModuleId,
                    IsHaveTableQuestion = x.ClinicalForm.ClinicalDataTrialSet.TrialClinicalQuestionList.Any(y => y.ClinicalQuestionType == ReadingQestionType.Table || y.ClinicalQuestionType == ReadingQestionType.BasicTable)
                }).ToListAsync();


            result.CurrentPageData.ForEach(x =>
            {
                if (x.IsCRCConfirm)
                {
                    x.ClinicalFormList = confirmList.Where(y => y.ReadModuleId == x.ReadModuleId).Select(y => new GetCRCBeConfirmListOutDto()
                    {
                        CheckDate = y.CheckDate,
                        ClinicalDataSetName = y.ClinicalDataSetName.LanguageName(y.ClinicalDataSetEnName, _userInfo.IsEn_Us),
                        ClinicalDataSetEnName = y.ClinicalDataSetEnName,
                        ClinicalFormId = y.ClinicalFormId,
                        ClinicalDataTrialSetId = y.ClinicalDataTrialSetId,
                        IsHaveTableQuestion = y.IsHaveTableQuestion,
                    }).ToList();
                }
                else
                {
                    if (x.ReadingSetType == ReadingSetType.ImageReading)
                    {
                        x.ClinicalFormList = formList.Where(y => y.ClinicalDataLevel == ClinicalLevel.ImageRead && y.CheckDate <= x.LatestScanDate && y.SubjectId == x.SubjectId)

                       .Select(y => new GetCRCBeConfirmListOutDto()
                       {
                           CheckDate = y.CheckDate ?? default(DateTime),
                           ClinicalDataSetName = y.ClinicalDataSetName.LanguageName(y.ClinicalDataSetEnName, _userInfo.IsEn_Us),
                           ClinicalDataSetEnName = y.ClinicalDataSetEnName,
                           ClinicalFormId = y.ClinicalFormId,
                           ClinicalDataTrialSetId = y.ClinicalDataTrialSetId,
                           IsHaveTableQuestion = y.IsHaveTableQuestion,
                       }).ToList();
                    }
                    else
                    {
                        x.ClinicalFormList = formList.Where(y => y.ClinicalDataLevel == ClinicalLevel.OncologyRead && y.CheckDate <= x.LatestScanDate && y.SubjectId == x.SubjectId)
                        .Select(y => new GetCRCBeConfirmListOutDto()
                        {
                            CheckDate = y.CheckDate ?? default(DateTime),
                            ClinicalDataSetName = y.ClinicalDataSetName.LanguageName(y.ClinicalDataSetEnName, _userInfo.IsEn_Us),
                            ClinicalDataSetEnName = y.ClinicalDataSetEnName,
                            ClinicalFormId = y.ClinicalFormId,
                            ClinicalDataTrialSetId = y.ClinicalDataTrialSetId,
                            IsHaveTableQuestion = y.IsHaveTableQuestion,
                        }).ToList();
                    }
                }
            });
            return result;
        }

        /// <summary>
        /// 获取CRC待确认列表
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<List<GetCRCBeConfirmListOutDto>> GetCRCBeConfirmList(GetCRCBeConfirmListInDto inDto)
        {
            var result = (await this.GetCRCConfirmList(new GetCRCConfirmListInDto()
            {
                ReadModuleId = inDto.ReadModuleId,
                TrialId = inDto.TrialId,
                PageIndex = 1,
                PageSize = 9999,

            })).CurrentPageData.SelectMany(x => x.ClinicalFormList).ToList();
            return result.OrderBy(x => x.ClinicalDataSetName).ThenBy(x => x.CheckDate).ToList();
        }


        /// <summary>
        /// 获取临床数据表格信息  查看没有表格问题的列表
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<(List<GetClinicalTableListOutDto>, object)> GetClinicalTableList(GetClinicalTableListInDto inDto)
        {

            var readModule = await _readModuleRepository.Where(x => x.Id == inDto.ReadModuleId).FirstNotNullAsync();

            var confirmList = (await this.GetCRCConfirmList(new GetCRCConfirmListInDto()
            {
                ReadModuleId = inDto.ReadModuleId,
                TrialId = inDto.TrialId,
                PageIndex = 1,
                PageSize = 9999,

            })).CurrentPageData.SelectMany(x => x.ClinicalFormList).ToList();

            var clinicalDataTrialSetIds = confirmList.Select(x => x.ClinicalDataTrialSetId).Distinct().ToList();
            var clinicalFormIds = confirmList.Select(x => x.ClinicalFormId).ToList();

            var questionList = await _trialClinicalQuestionRepository.Where(x => clinicalDataTrialSetIds.Contains(x.TrialClinicalId)
            && x.ClinicalQuestionType != ReadingQestionType.Group
            && x.ClinicalQuestionType != ReadingQestionType.Table
            && x.ClinicalQuestionType != ReadingQestionType.BasicTable
            ).OrderBy(x => x.TrialClinicalId).ThenBy(x => x.ShowOrder)
               .ProjectTo<TrialClinicalQuestionDto>(_mapper.ConfigurationProvider).ToListAsync();
            var answers = await _clinicalQuestionAnswerRepository.Where(x => clinicalFormIds.Contains(x.ClinicalFormId))
            .Select(x => new
            {
                x.ClinicalDataTrialSetId,
                x.ClinicalFormId,
                x.ClinicalForm.CheckDate,
                x.QuestionId,
                x.Answer
            })
            .ToListAsync();
            List<GetClinicalTableListOutDto> result = new List<GetClinicalTableListOutDto>();
            clinicalDataTrialSetIds.ForEach(x =>
            {
                GetClinicalTableListOutDto dto = new GetClinicalTableListOutDto();
                dto.ModuleName = readModule.ModuleName;
                dto.ClinicalDataSetName = confirmList.Where(y => y.ClinicalDataTrialSetId == x).Select(y => y.ClinicalDataSetName).First();
                dto.QuestionList = questionList.Where(y => y.TrialClinicalId == x).OrderBy(y => y.ShowOrder).ToList();
                dto.AnswerList = new List<Dictionary<string, string>>();
                var ClinicalFormIds = answers.Where(y => y.ClinicalDataTrialSetId == x).OrderBy(x => x.CheckDate).Select(x => x.ClinicalFormId).Distinct().ToList();
                ClinicalFormIds.ForEach(z =>
                {
                    var dic = answers.Where(y => y.ClinicalFormId == z).OrderBy(y => y.CheckDate).ToDictionary(x => x.QuestionId.ToString(), x => x.Answer);
                    dic.Add("ClinicalFormId", z.ToString());
                    dic.Add("TrialId", inDto.TrialId.ToString());
                    dic.Add("SubjectId", readModule.SubjectId.ToString());
                    dic.Add("ClinicalDataTrialSetId", x.ToString());

                    dto.AnswerList.Add(dic);

                });
                result.Add(dto);
            });
            return (result, new
            {
                readModule.ModuleName,
            });

        }


        /// <summary>
        /// 获取临床数据表格信息  查看有表格问题的列表
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<(List<GetClinicalDateListOutDto>, object)> GetClinicalDateList(GetCRCBeConfirmListInDto inDto)
        {
            var readModule = await _readModuleRepository.Where(x => x.Id == inDto.ReadModuleId).FirstNotNullAsync();
            var confirmList = (await this.GetCRCConfirmList(new GetCRCConfirmListInDto()
            {
                ReadModuleId = inDto.ReadModuleId,
                TrialId = inDto.TrialId,
                PageIndex = 1,
                PageSize = 9999,

            })).CurrentPageData.SelectMany(x => x.ClinicalFormList).ToList();

            var clinicalDataTrialSetIds = confirmList.Select(x => x.ClinicalDataTrialSetId).Distinct().ToList();

            List<GetClinicalDateListOutDto> result = new List<GetClinicalDateListOutDto>();

            clinicalDataTrialSetIds.ForEach(x =>
            {

                result.Add(new GetClinicalDateListOutDto()
                {
                    ClinicalDataSetName = confirmList.Where(y => y.ClinicalDataTrialSetId == x).Select(y => y.ClinicalDataSetName).First(),
                    DateList = confirmList.Where(y => y.ClinicalDataTrialSetId == x).ToList()

                });

            });

            return (result, new
            {
                readModule.ModuleName,
            });
        }

        /// <summary>
        /// CRC 确认临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<IResponseOutput> CRCConfirmClinical(CRCConfirmClinicalInDto inDto)
        {

            var readModule = await _readModuleRepository.Where(x => x.Id == inDto.ReadModuleId).FirstNotNullAsync();

            var confirmlist = (await this.GetCRCConfirmList(new GetCRCConfirmListInDto()
            {
                TrialId = inDto.TrialId,
                SubjectId = readModule.SubjectId,
                IsCRCConfirm = false,
                TrialReadingCriterionId = readModule.TrialReadingCriterionId,
                //ReadModuleId = inDto.ReadModuleId,
                PageIndex = 1,
                PageSize = 9999,
            })).CurrentPageData.ToList();

            var presentData = confirmlist.Where(x => x.ReadModuleId == inDto.ReadModuleId).First();

            confirmlist = confirmlist.Where(x => x.LatestScanDate <= presentData.LatestScanDate).ToList();

            await _readModuleCriterionFromRepository.BatchDeleteNoTrackingAsync(x => x.ReadModuleId == inDto.ReadModuleId);
            List<ReadModuleCriterionFrom> needAddList = new List<ReadModuleCriterionFrom>()
            {

            };
            confirmlist.ForEach(x =>
            {
                x.ClinicalFormList.ForEach(y =>
                {
                    needAddList.Add(new ReadModuleCriterionFrom()
                    {
                        ClinicalFormId = y.ClinicalFormId,
                        ReadModuleId = x.ReadModuleId,
                        SubjectId = x.SubjectId,
                        TrialId = inDto.TrialId,
                    });
                });
            });

            foreach (var item in confirmlist)
            {
                await _readModuleRepository.UpdatePartialFromQueryAsync(x => x.Id == item.ReadModuleId, x => new ReadModule()
                {
                    IsCRCConfirm = true,
                    IsPMConfirm = item.ClinicalFormList.Count() == 0 ? true : false,
                    IsNotNeedPMConfirm = item.ClinicalFormList.Count() == 0 ? true : false,
                });
            }

            await _readModuleCriterionFromRepository.AddRangeAsync(needAddList);

            await _readModuleCriterionFromRepository.SaveChangesAsync();
            await _iReadingClinicalDataService.DealVisiTaskClinicalDataSignedAsync(inDto.TrialId, inDto.SubjectId, inDto.ReadModuleId, false, readModule.TrialReadingCriterionId);
            return ResponseOutput.Ok(true);
        }

        /// <summary>
        /// CRC 取消确认
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<IResponseOutput> CRCCancelConfirmClinical(CRCCancelConfirmClinicalInDto inDto)
        {

            var readModule = await _readModuleRepository.Where(x => x.Id == inDto.ReadModuleId).FirstNotNullAsync();
            var dataList = (await this.GetCRCConfirmList(new GetCRCConfirmListInDto()
            {
                TrialId = inDto.TrialId,
                SubjectId = readModule.SubjectId,
                TrialReadingCriterionId = readModule.TrialReadingCriterionId,
                PageIndex = 1,
                PageSize = 9999,
            })).CurrentPageData;

            var presentData = dataList.Where(x => x.ReadModuleId == inDto.ReadModuleId).First();

            if (dataList.Any(x => x.IsCRCConfirm && x.LatestScanDate > presentData.LatestScanDate && x.ReadingSetType == presentData.ReadingSetType))
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_unableToCancel"]);
            }

            if (presentData.IsPMConfirm)
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_unableToCancelPMConfirmed"]);
            }

            if (presentData.IsNotNeedPMConfirm)
            {
                await _readModuleRepository.UpdatePartialFromQueryAsync(x => presentData.ReadModuleId == x.Id, x => new ReadModule()
                {
                    IsPMConfirm = false,
                    IsCRCConfirm = false,
                    IsNotNeedPMConfirm = false,
                });
            }
            else
            {
                await _readModuleRepository.UpdatePartialFromQueryAsync(x => presentData.ReadModuleId == x.Id, x => new ReadModule()
                {
                    IsCRCApplicationRevoke = true,
                });
            }


            //await _readModuleCriterionFromRepository.BatchDeleteNoTrackingAsync(x=>x.ReadModuleId== presentData.ReadModuleId);

            await _readModuleCriterionFromRepository.SaveChangesAsync();
            return ResponseOutput.Ok(true);
        }

        /// <summary>
        /// PM确认临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        /// <exception cref="BusinessValidationFailedException"></exception>
        [HttpPost]
        public async Task<IResponseOutput> PMConfirmClinical(CRCConfirmClinicalInDto inDto)
        {
            var readModuleData = await _readModuleRepository.Where(x => x.Id == inDto.ReadModuleId).FirstNotNullAsync();
            if (!readModuleData.IsCRCConfirm)
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_PMUnableToOperate"]);
            }

            if (readModuleData.IsCRCApplicationRevoke && inDto.IsConfirm)
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_PMUnableToConfirm"]);
            }

            if (!readModuleData.IsCRCApplicationRevoke && !inDto.IsConfirm)
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalAnswer_PMUnableToWithdraw"]);
            }

            if (inDto.IsConfirm)
            {
                await _readModuleRepository.UpdatePartialFromQueryAsync(x => inDto.ReadModuleId == x.Id, x => new ReadModule()
                {
                    IsPMConfirm = true,
                    IsClinicalDataBlind = inDto.IsClinicalDataBlind,
                    IsClinicalDataComplete = inDto.IsClinicalDataComplete,
                });
                await _readModuleRepository.SaveChangesAsync();
                await _iReadingClinicalDataService.DealVisiTaskClinicalDataSignedAsync(inDto.TrialId, inDto.SubjectId, inDto.ReadModuleId, false, readModuleData.TrialReadingCriterionId);
            }
            else
            {
                await _readModuleRepository.UpdatePartialFromQueryAsync(x => inDto.ReadModuleId == x.Id, x => new ReadModule()
                {
                    IsCRCConfirm = false,
                    IsCRCApplicationRevoke = false,
                });
                await _readModuleRepository.SaveChangesAsync();
                await _readModuleCriterionFromRepository.BatchDeleteNoTrackingAsync(x => x.ReadModuleId == inDto.ReadModuleId);

            }




            return ResponseOutput.Ok(true);
        }

    }
}