using Microsoft.AspNetCore.Mvc;
using IRaCIS.Core.Application.Service.Reading.Dto;
using MassTransit;
using IRaCIS.Core.Domain.Models;
using IRaCIS.Core.Application.Interfaces;
using IRaCIS.Core.Domain.Share;
using IRaCIS.Core.Infrastructure;
using System.Linq;
using System.Linq.Expressions;
using System;
using MathNet.Numerics.Optimization.LineSearch;

namespace IRaCIS.Application.Services
{
    /// <summary>
    /// 临床数据配置
    /// </summary>
    [ApiExplorerSettings(GroupName = "Reading")]
    public class ClinicalDataSetService : BaseService
    {
        public IClinicalQuestionService _iClinicalQuestionService;
        public IRepository<SubjectVisit> _subjectVisitRepository;

        private readonly IRepository<ClinicalDataTrialSet> _clinicalDataTrialSetRepository;
		private readonly IRepository<TrialClinicalDataSetCriterion> _trialClinicalDataSetCriterionRepository;
		private readonly IRepository<ReadingQuestionCriterionTrial> _iReadingQuestionCriterionTrialRepository;
		private readonly IRepository<ClinicalDataSystemSet> _clinicalDataSystemSetRepository;
        private readonly IRepository<PreviousPDF> _previousPDFRepository;
		private readonly IRepository<Dictionary> _dictionaryRepository;
		private readonly IRepository<Trial> _trialRepository;
        private readonly IRepository<TrialClinicalQuestion> _trialClinicalQuestionRepository;

        private readonly IRepository<SystemClinicalQuestion> _systemClinicalQuestionRepository;

        public ClinicalDataSetService(IRepository<SubjectVisit> subjectVisitRepository,
              IClinicalQuestionService iClinicalQuestionService,
            IRepository<ClinicalDataTrialSet> ClinicalDataTrialSetRepository,
			  IRepository<TrialClinicalDataSetCriterion> trialClinicalDataSetCriterionRepository,
				IRepository<ReadingQuestionCriterionTrial> iReadingQuestionCriterionTrialRepository,
			IRepository<ClinicalDataSystemSet> ClinicalDataSystemSetRepository,
            IRepository<PreviousPDF> previousPDFRepository,
			  IRepository<Dictionary> dictionaryRepository,
              IRepository<TrialClinicalQuestion> trialClinicalQuestionRepository,
  IRepository<SystemClinicalQuestion> systemClinicalQuestionRepository,

            IRepository<Trial> trialRepository

          
          )
        {
            _iClinicalQuestionService = iClinicalQuestionService;
            _subjectVisitRepository = subjectVisitRepository;
            _trialClinicalQuestionRepository = trialClinicalQuestionRepository;
            _systemClinicalQuestionRepository = systemClinicalQuestionRepository;
            _clinicalDataTrialSetRepository = ClinicalDataTrialSetRepository;
			this._trialClinicalDataSetCriterionRepository = trialClinicalDataSetCriterionRepository;
			this._iReadingQuestionCriterionTrialRepository = iReadingQuestionCriterionTrialRepository;
			_clinicalDataSystemSetRepository = ClinicalDataSystemSetRepository;
            this._previousPDFRepository = previousPDFRepository;
			this._dictionaryRepository = dictionaryRepository;
			this._trialRepository = trialRepository;
        }


        /// <summary>
        /// 应用系统临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        /// <exception cref="BusinessValidationFailedException"></exception>
        [HttpPost]
        public async Task<IResponseOutput> ApplySystemClinical(ApplySystemClinicalInDto inDto)
        {

            var isNeedVerify = await _clinicalDataSystemSetRepository.AnyAsync(x => x.Id == inDto.SystemClinicalId && (x.ClinicalDataLevel == ClinicalLevel.ImageRead || x.ClinicalDataLevel == ClinicalLevel.OncologyRead)
			&& x.ClinicalUploadType == ClinicalUploadType.Structuring && x.UploadRole == UploadRole.CRC
            );

			if (_systemClinicalQuestionRepository.Where(x => x.SystemClinicalId == inDto.SystemClinicalId).Count() == 0)
			{
				throw new BusinessValidationFailedException(_localizer["ClinicalComment_dataNotConfigured"]);
			}
			if (isNeedVerify&&_systemClinicalQuestionRepository.Where(x => x.SystemClinicalId == inDto.SystemClinicalId && x.IsCheckDate).Count() != 1)
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalDataSet_Apply"]);
              
            }

            await _clinicalDataSystemSetRepository.UpdatePartialFromQueryAsync(x => x.Id == inDto.SystemClinicalId, x => new ClinicalDataSystemSet()
            {
                IsApply = true
            });


            await _clinicalDataSystemSetRepository.SaveChangesAsync();

            return ResponseOutput.Ok(true);
        }

        /// <summary>
        /// 应用项目临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        /// <exception cref="BusinessValidationFailedException"></exception>
        [HttpPost]
        public async Task<IResponseOutput> ApplyTrialClinical(ApplyTrialClinicalInDto inDto)
        {

			var isNeedVerify = await _clinicalDataTrialSetRepository.AnyAsync(x => x.Id == inDto.TrialClinicalId && (x.ClinicalDataLevel == ClinicalLevel.ImageRead|| x.ClinicalDataLevel==ClinicalLevel.OncologyRead)
		  && x.ClinicalUploadType == ClinicalUploadType.Structuring && x.UploadRole == UploadRole.CRC
		 );

            if (_trialClinicalQuestionRepository.Where(x => x.TrialClinicalId == inDto.TrialClinicalId).Count() == 0)
            {
				throw new BusinessValidationFailedException(_localizer["ClinicalComment_dataNotConfigured"]);
			}

			if (isNeedVerify&&_trialClinicalQuestionRepository.Where(x =>  x.TrialClinicalId == inDto.TrialClinicalId && x.IsCheckDate).Count() != 1)
            {
                throw new BusinessValidationFailedException(_localizer["ClinicalDataSet_Apply"]);

            }

            await _clinicalDataTrialSetRepository.UpdatePartialFromQueryAsync(x => x.Id == inDto.TrialClinicalId, x => new ClinicalDataTrialSet()
            {
                IsApply = true
            });


            await _clinicalDataTrialSetRepository.SaveChangesAsync();

            return ResponseOutput.Ok(true);
        }


        #region 系统
        /// <summary>
        /// 新增或者修改(系统)
        /// </summary>
        /// <param name="indto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<IResponseOutput> AddOrUpdateClinicalDataSystemSet(ClinicalDataSystemSetAddOrEdit indto)
        {
            if (indto.ClinicalUploadType == ClinicalUploadType.Table || indto.ClinicalUploadType == ClinicalUploadType.PDF)
            {
                indto.IsApply = true;
            }
            var dictionary = await _dictionaryRepository.Where(x => x.Parent.Code == "ClinicalDataType" && x.Code == indto.ClinicalDataSetEnum.ToString()).FirstNotNullAsync();
            indto.ClinicalDataSetName = dictionary.ValueCN;
            indto.ClinicalDataSetEnName = dictionary.Value;
			var existsQuery = _clinicalDataSystemSetRepository
              .WhereIf(indto.Id != null, x => x.Id != indto.Id)
              .Where(x => x.ClinicalDataSetName == indto.ClinicalDataSetName||x.ClinicalDataSetEnName==indto.ClinicalDataSetEnName);

       

            if (await existsQuery.AnyAsync())
            {
                //---存在同类型的临床数据,操作失败
                return ResponseOutput.NotOk(_localizer["ClinicalDataSet_DupTypeFail"]);
            }

            indto.CriterionEnumListStr= $"|{String.Join('|', indto.CriterionEnumList)}|";

            var entity = await _clinicalDataSystemSetRepository.InsertOrUpdateAsync(indto);

            //entity.SystemClinicalDataCriterionList = indto.SystemCriterionIdList.Select(t => new SystemClinicalDataCriterion()
            //{
            //    SystemClinicalDataSetId = entity.Id,
            //    SystemReadingCriterionId = t
            //}).ToList();

            //if (indto.Id != null)
            //{
            //    await _systemClinicalDataCriterionRepository.BatchDeleteNoTrackingAsync(t => t.SystemClinicalDataSetId == entity.Id);

            //    await _systemClinicalDataCriterionRepository.AddRangeAsync(entity.SystemClinicalDataCriterionList);
            //}

            await _clinicalDataSystemSetRepository.SaveChangesAsync();

            return ResponseOutput.Ok(entity.Id.ToString());
        }

        /// <summary>
        /// 获取系统临床数据（系统）
        /// </summary>
        /// <returns></returns>
        [HttpPost]
        public async Task<List<ClinicalDataSystemSetView>> GetSystemClinicalDataSystemSetList(GetTrialClinicalDataSystemIndto inDto)
        {
            return await _clinicalDataSystemSetRepository.AsQueryable()
                 .WhereIf(inDto.ClinicalDataLevel != null, x => x.ClinicalDataLevel == inDto.ClinicalDataLevel)
                 .WhereIf(inDto.ClinicalUploadType != null, x => x.ClinicalUploadType == inDto.ClinicalUploadType)
                 .WhereIf(inDto.ClinicalDataSetName != String.Empty, x => x.ClinicalDataSetName.Contains(inDto.ClinicalDataSetName))

                 .ProjectTo<ClinicalDataSystemSetView>(_mapper.ConfigurationProvider).ToListAsync();
        }

        /// <summary>
        /// 删除(系统)
        /// </summary>
        /// <param name="id"></param>
        /// <returns></returns>
        [HttpDelete("{id:guid}")]
        public async Task<IResponseOutput> DeleteClinicalSystemSetData(Guid id)
        {
            await _clinicalDataSystemSetRepository.DeleteFromQueryAsync(x => x.Id == id, true);
            return ResponseOutput.Result(true);
        }

        #endregion



        #region 项目
        /// <summary>
        /// 新增或者修改(项目)
        /// </summary>
        /// <param name="indto"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<IResponseOutput> AddOrUpdateClinicalDataTrialSet(ClinicalDataTrialSetAddOrEdit indto)
        {

            if (indto.ClinicalUploadType == ClinicalUploadType.Table || indto.ClinicalUploadType == ClinicalUploadType.PDF)
            {
                indto.IsApply = true;
            }

            var existsQuery = _clinicalDataTrialSetRepository
             .WhereIf(indto.Id != null, x => x.Id != indto.Id)
             .Where(x => (x.ClinicalDataSetName == indto.ClinicalDataSetName||x.ClinicalDataSetEnName==indto.ClinicalDataSetEnName) && x.TrialId == indto.TrialId);

            if (await existsQuery.AnyAsync())
            {
                //---存在同类型的临床数据,操作失败
                return ResponseOutput.NotOk(_localizer["ClinicalDataSet_DupTypeFail"]);
            }
            if (indto.Id != null && indto.IsApply == null)
            {
                indto.IsApply = await _clinicalDataTrialSetRepository.Where(x => x.Id == indto.Id).Select(x => x.IsApply).FirstOrDefaultAsync();
            }

            //indto.CriterionEnumListStr = $"|{String.Join('|', indto.CriterionEnumList)}|";

            //var entity = _mapper.Map<TEntity>(from);

            indto.CreateTime = DateTime.Now;
			var entity = await _clinicalDataTrialSetRepository.InsertOrUpdateAsync(indto);

            entity.TrialClinicalDataSetCriteriaList = indto.TrialCriterionIdList.Select(t => new TrialClinicalDataSetCriterion()
            {
                TrialClinicalDataSetId = entity.Id,
                TrialReadingCriterionId = t
            }).ToList();

            if (indto.Id != null)
            {
                await _trialClinicalDataSetCriterionRepository.DeleteFromQueryAsync(t => t.TrialClinicalDataSetId == entity.Id);

                await _repository.AddRangeAsync<TrialClinicalDataSetCriterion>(entity.TrialClinicalDataSetCriteriaList);
            }



            await _clinicalDataTrialSetRepository.SaveChangesAsync();
            return ResponseOutput.Ok(entity.Id.ToString());
        }





        /// <summary>
        /// 获取项目的临床数据
        /// </summary>
        /// <param name="inDto"></param>
        /// <returns></returns>
        [HttpPost]
        [UnitOfWork]
        public async Task<List<ClinicalDataTrialSetView>> GetTrialClinicalDataTrialSetList(GetTrialClinicalDataTrialIndto inDto)
        {
            await this.AddTrialClinicalDataTrialSet(inDto.TrialId);
            Expression<Func<ClinicalDataTrialSet, bool>> predicate = null;
			if (inDto.CriterionIds != null)
            {

			 	List<string> criterionTypes = (await _iReadingQuestionCriterionTrialRepository.Where(x => inDto.CriterionIds.Contains(x.Id)).Select(x => x.CriterionType).ToListAsync())
					.Select(x => ((int)x).ToString()).ToList();
				predicate = x =>x.SystemClinicalDataSetId == null;
                foreach (var item in criterionTypes)
                {
                    Expression<Func<ClinicalDataTrialSet, bool>> typeExpression = x =>x.ClinicalDataSystemSet==null|| x.ClinicalDataSystemSet.CriterionEnumListStr.Contains(item);
                    predicate = predicate.Or(typeExpression);

				}
			}
			var trialClinicalDataList = await _clinicalDataTrialSetRepository.AsQueryable()
               .Where(x => x.TrialId == inDto.TrialId)
               .WhereIf(inDto.CriterionIds != null, predicate)
               .WhereIf(inDto.ClinicalDataLevel != null, x => x.ClinicalDataLevel == inDto.ClinicalDataLevel)
               .WhereIf(inDto.ClinicalUploadType != null, x => x.ClinicalUploadType == inDto.ClinicalUploadType)
               .WhereIf(inDto.ClinicalDataSetName != String.Empty, x => x.ClinicalDataSetName.Contains(inDto.ClinicalDataSetName))
               .ProjectTo<ClinicalDataTrialSetView>(_mapper.ConfigurationProvider, new
			   {
				   CriterionIds = inDto.CriterionIds

			   }).ToListAsync();
            return trialClinicalDataList;
        }


		/// <summary>
		/// 删除(项目)
		/// </summary>
		/// <param name="id"></param>
		/// <returns></returns>
		[HttpDelete("{id:guid}")]
        public async Task<IResponseOutput> DeleteClinicalTrialSetData(Guid id)
        {
            await _clinicalDataTrialSetRepository.DeleteFromQueryAsync(x => x.Id == id, true);
            return ResponseOutput.Result(true);
        }

        #endregion


        #region 系统和项目标准下拉   界面上配置和临床数据关联  废弃

        //[HttpPost]
        //public async Task<List<SystemCriterionSelectDto>> GetSystemCriterionSelectList(SystemCriterionSelectQuery inQuery)
        //{
        //    return await _repository.Where<ReadingQuestionCriterionSystem>()
        //          .WhereIf(!string.IsNullOrEmpty(inQuery.CriterionName), t => t.CriterionName.Contains(inQuery.CriterionName))
        //          .WhereIf(inQuery.IsEnable != null, t => t.IsEnable == inQuery.IsEnable)
        //          .WhereIf(inQuery.IsCompleteConfig != null, t => t.IsCompleteConfig == inQuery.IsCompleteConfig)
        //          .Select(t => new SystemCriterionSelectDto()
        //          {
        //              Id = t.Id,
        //              CriterionName = t.CriterionName,
        //              IsCompleteConfig = t.IsCompleteConfig,
        //              IsEnable = t.IsEnable
        //          }).ToListAsync();
        //}


        //[HttpPost]
        //public async Task<List<TrialCriterionSelectDto>> GetTrialCriterionSelectList(TrialCriterionSelectQuery inQuery)
        //{
        //    return await _repository.Where<ReadingQuestionCriterionTrial>(t => t.TrialId == inQuery.TrialId)
        //       .WhereIf(!string.IsNullOrEmpty(inQuery.CriterionName), t => t.CriterionName.Contains(inQuery.CriterionName))
        //       .WhereIf(inQuery.IsEnable != null, t => t.IsEnable == inQuery.IsEnable)
        //       .WhereIf(inQuery.IsCompleteConfig != null, t => t.IsCompleteConfig == inQuery.IsCompleteConfig)
        //       .Select(t => new TrialCriterionSelectDto()
        //       {
        //           Id = t.Id,
        //           CriterionName = t.CriterionName,
        //           IsCompleteConfig = t.IsCompleteConfig,
        //           IsEnable = t.IsEnable
        //       }).ToListAsync();
        //}


        #endregion



        #region 将系统配置添加到项目配置

        /// <summary>
        /// 将系统配置添加到项目配置
        /// </summary>
        /// <param name="trialId"></param>
        /// <returns></returns>

        private async Task AddTrialClinicalDataTrialSet(Guid trialId)
        {

            #region MyRegion

            //不存在的时候，就将系统数据同步到项目临床数据配置
            if (!await _clinicalDataTrialSetRepository.AnyAsync(x => x.TrialId == trialId && x.SystemClinicalDataSetId != null))
            {
                var systemClinicalDataList = await _clinicalDataSystemSetRepository.Where(x=>x.IsApply).AsQueryable().ToListAsync();
                var systemIds = systemClinicalDataList.Select(x => x.Id).ToList();

                var trialSystemClinicalDataSetIds = await _clinicalDataTrialSetRepository.Where(x => x.TrialId == trialId && x.SystemClinicalDataSetId != null).Select(x => x.SystemClinicalDataSetId.Value).ToListAsync();

                var needAddids = systemIds.Except(trialSystemClinicalDataSetIds).ToList();

                var systemDataList = systemClinicalDataList.Where(x => needAddids.Contains(x.Id)).ToList();

                var readingCriterionList = _repository.Where<ReadingQuestionCriterionTrial>(t => t.TrialId == trialId).Where(t => t.ReadingQuestionCriterionSystemId != null)
                    .Select(t => new { t.ReadingQuestionCriterionSystemId, TrialReadingCriterionId = t.Id ,t.CriterionType}).ToList();


                List<ClinicalDataTrialSet> dataSets = systemDataList.Select(x => new ClinicalDataTrialSet()
                {
                    Id = NewId.NextGuid(),
                    SystemClinicalDataSetId = x.Id,
                    ClinicalDataSetName = x.ClinicalDataSetName,
                    ClinicalDataLevel = x.ClinicalDataLevel,
                    ClinicalUploadType = x.ClinicalUploadType,
                    ClinicalDataSetEnName=x.ClinicalDataSetEnName,
                    UploadRole = x.UploadRole,
                    FileName = x.FileName,
                    Path = x.Path,
                    TrialId = trialId,
                    IsApply = x.IsApply,

                    //项目不采用 标准枚举字符串的方式
                    //CriterionEnumListStr=x.CriterionEnumListStr

                    TrialClinicalDataSetCriteriaList = readingCriterionList.Where(t => x.CriterionEnumList.Contains( (int )t.CriterionType)).Select(c =>
                    new TrialClinicalDataSetCriterion() { TrialReadingCriterionId = c.TrialReadingCriterionId }).ToList()
                }).ToList();



                await _clinicalDataTrialSetRepository.AddRangeAsync(dataSets);

                var result = await _clinicalDataTrialSetRepository.SaveChangesAsync();


                await _iClinicalQuestionService.SynchronizationQuestion(dataSets.Select(x => new SynchronizationQuestionDto()
                {
                    SystemClinicalId = x.SystemClinicalDataSetId.Value,
                    TrialClinicalId = x.Id,

                }).ToList());
            }

            #endregion


            #region OLd
            //var syncClinicalDataTime = await _trialRepository.Where(x => x.Id == trialId).Select(x => x.SyncClinicalDataTime).FirstOrDefaultAsync();
            //if (syncClinicalDataTime == null)
            //{
            //    var systemClinicalDataList = await _clinicalDataSystemSetRepository.AsQueryable().Include(t => t.SystemClinicalDataCriterionList).ToListAsync();
            //    var systemIds = systemClinicalDataList.Select(x => x.Id).ToList();

            //    var trialSystemClinicalDataSetIds = await _clinicalDataTrialSetRepository.Where(x => x.TrialId == trialId && x.SystemClinicalDataSetId != null).Select(x => x.SystemClinicalDataSetId.Value).ToListAsync();

            //    var needAddids = systemIds.Except(trialSystemClinicalDataSetIds).ToList();

            //    var systemDataList = systemClinicalDataList.Where(x => needAddids.Contains(x.Id)).ToList();

            //    var readingCriterionList = _repository.Where<ReadingQuestionCriterionTrial>(t => t.TrialId == trialId).Where(t => t.ReadingQuestionCriterionSystemId != null)
            //        .Select(t => new { t.ReadingQuestionCriterionSystemId, TrialReadingCriterionId = t.Id }).ToList();


            //    List<ClinicalDataTrialSet> dataSets = systemDataList.Select(x => new ClinicalDataTrialSet()
            //    {
            //        Id = NewId.NextGuid(),
            //        SystemClinicalDataSetId = x.Id,
            //        ClinicalDataSetName = x.ClinicalDataSetName,
            //        ClinicalDataLevel = x.ClinicalDataLevel,
            //        ClinicalUploadType = x.ClinicalUploadType,
            //        UploadRole = x.UploadRole,
            //        FileName = x.FileName,
            //        Path = x.Path,
            //        TrialId = trialId,

            //        TrialClinicalDataCriterionList = readingCriterionList.Where(t => x.SystemClinicalDataCriterionList.Select(c => (Guid?)c.SystemReadingCriterionId).ToList().Contains(t.ReadingQuestionCriterionSystemId)).Select(c =>
            //        new TrialClinicalDataCriterion() { TrialReadingCriterionId = c.TrialReadingCriterionId }).ToList()
            //    }).ToList();


            //    #region 临床数据标准


            //    // dataSets.ForEach(x =>
            //    //x.TrialClinicalDataCriterionList = systemClinicalDataList.Where(t => t.Id == x.SystemClinicalDataSetId)
            //    //                      .Select(t => new TrialClinicalDataCriterion() { TrialReadingCriterionId = x.cl }).ToList()
            //    //                      );

            //    #endregion



            //    await _clinicalDataTrialSetRepository.AddRangeAsync(dataSets);

            //    //var needUpdateitemList = await _clinicalDataTrialSetRepository.Where(x => x.TrialId == trialId && needUpdateIds.Contains(x.SystemClinicalDataSetId.Value)).ToListAsync();
            //    //foreach (var item in needUpdateitemList)
            //    //{
            //    //   var systemData = systemClinicalDataList.FirstOrDefault(x => x.Id == item.SystemClinicalDataSetId);
            //    //   await _clinicalDataTrialSetRepository.UpdatePartialNoQueryAsync(item.Id,x=>new ClinicalDataTrialSet() {

            //    //       ClinicalDataSetName = systemData.ClinicalDataSetName,
            //    //       ClinicalDataLevel = systemData.ClinicalDataLevel,
            //    //       ClinicalUploadType = systemData.ClinicalUploadType,
            //    //       UploadRole = systemData.UploadRole,
            //    //       FileName = systemData.FileName,
            //    //       Path = systemData.Path,
            //    //   });
            //    //}

            //    await _trialRepository.BatchUpdateNoTrackingAsync(x => x.Id == trialId, x => new Trial()
            //    {
            //        SyncClinicalDataTime = DateTime.Now,
            //    });


            //    var result = await _clinicalDataTrialSetRepository.SaveChangesAsync();

            //}

            #endregion


        }
        #endregion
    }
}