using IRaCIS.Core.Domain.Share;
using System.Linq;
using ZstdSharp.Unsafe;

namespace IRaCIS.Core.Domain.Models;

[Comment("项目 - 项目基本信息与配置")]
[Table("Trial")]
public partial class Trial : BaseFullDeleteAuditEntity
{
    #region 导航属性
    [JsonIgnore]
    [ForeignKey("SponsorId")]
    public Sponsor Sponsor { get; set; }
    [JsonIgnore]
    [ForeignKey("CROId")]
    public CRO CRO { get; set; }
    [JsonIgnore]
    public List<TrialBodyPart> TrialBodyPartList { get; set; }
    [JsonIgnore]
    public List<TaskMedicalReview> TaskMedicalReviewList { get; set; }
    [JsonIgnore]
    public List<TaskConsistentRule> TaskConsistentRuleList { get; set; }
    [JsonIgnore]
    public List<SubjectUser> SubjectDoctorUserList { get; set; } = new List<SubjectUser>();
    [JsonIgnore]
    public List<VisitTask> VisitTaskList { get; set; } = new List<VisitTask>() { };

    [JsonIgnore]
    public List<VisitTaskReReading> VisitTaskReReadingList { get; set; }
    [JsonIgnore]
    public List<TrialSiteSurvey> TrialSiteSurveyList { get; set; } = new List<TrialSiteSurvey>();

    [JsonIgnore]
    public List<TrialDocument> TrialDocumentList { get; set; }
    [JsonIgnore]
    public List<Enroll> EnrollList { get; set; } = new List<Enroll>();
    [JsonIgnore]
    public List<Workload> WorkloadList { get; set; } = new List<Workload>();
    [JsonIgnore]
    public List<TrialUserRole> TrialUserRoleList { get; set; } = new List<TrialUserRole>();

    [JsonIgnore]
    public List<TrialIdentityUser> TrialIdentityUserList { get; set; }  
    [JsonIgnore]
    public List<ReadingQuestionCriterionTrial> TrialReadingCriterionList { get; set; } = new List<ReadingQuestionCriterionTrial>();
    [JsonIgnore]
    public List<Subject> SubjectList { get; set; } = new List<Subject>();
    [JsonIgnore]
    public List<SubjectVisit> SubjectVisitList { get; set; } = new List<SubjectVisit>();
    [JsonIgnore]
    public List<DicomStudy> StudyList { get; set; } = new List<DicomStudy>();
    [JsonIgnore]
    public List<TrialSite> TrialSiteList { get; set; } = new List<TrialSite>();
    [JsonIgnore]
    public List<TrialSiteUserRole> TrialSiteUserList { get; set; } = new List<TrialSiteUserRole>();
    [JsonIgnore]
    public List<ReadModule> ReadModuleList { get; set; } = new List<ReadModule>();
    [JsonIgnore]
    public List<UserFeedBack> UserFeedBackList { get; set; } = new List<UserFeedBack>();
    [JsonIgnore]
    [ForeignKey("IndicationTypeId")]
    public Dictionary IndicationType { get; set; }
    [JsonIgnore]
    [ForeignKey("PhaseId")]
    public Dictionary Phase { get; set; }
    [JsonIgnore]
    [ForeignKey("ReviewModeId")]
    public Dictionary ReviewMode { get; set; }

    [JsonIgnore]
    public List<ClinicalDataTrialSet> ClinicalDataTrialSetList { get; set; } = new List<ClinicalDataTrialSet> { };
    [JsonIgnore]
    public List<TrialStatusDetail> ClinicalTrialProjectDetails { get; set; } = new List<TrialStatusDetail> { };
    [JsonIgnore]
    public List<TrialDictionary> TrialDicList { get; set; } = new List<TrialDictionary>();

    [JsonIgnore]
    public List<ReadingClinicalData> ReadingClinicalDataList { get; set; }

    [JsonIgnore]
    public List<TrialStateChange> TrialStateChangeList { get; set; } = new List<TrialStateChange>();
    #endregion

    public Guid IndicationTypeId { get; set; } = Guid.Empty;
    public Guid? PhaseId { get; set; } = Guid.Empty;

    public string TrialCode { get; set; } = string.Empty;

    public int Code { get; set; }

    public string Indication { get; set; } = string.Empty;

    [Comment("入组那一块的状态")]
    public int TrialEnrollStatus { get; set; }

    [Comment("启动状态")]
    public string TrialStatusStr { get; set; } = StaticData.TrialState.TrialInitializing;

    public Guid? CROId { get; set; } = Guid.Empty;

    public Guid? SponsorId { get; set; } = Guid.Empty;
    public Guid? ReviewModeId { get; set; } = Guid.Empty;
    public string ProjectCycle { get; set; } = string.Empty;
    public int ExpectedPatients { get; set; }

    public decimal TimePointsPerPatient { get; set; }

    public int GRRReviewers { get; set; }

    public int TotalReviewers { get; set; }

    public string ReviewProtocol { get; set; } = string.Empty;

    public string MessageFromClient { get; set; } = string.Empty;

    public string Note { get; set; } = string.Empty;
    public string ReviewProtocolName { get; set; } = string.Empty;
    public string MessageFromClientName { get; set; } = string.Empty;
    public int Expedited { get; set; }
    public string DeclarationTypes { get; set; } = string.Empty;

    [NotMapped]
    public List<DeclarationType> DeclarationTypeEnumList => DeclarationTypes.Split('|', StringSplitOptions.RemoveEmptyEntries)
       .Select(s => Enum.Parse(typeof(DeclarationType), s)).Cast<DeclarationType>().ToList();

    [NotMapped]
    public List<AttendedReviewerType> AttendedReviewerTypeEnumList => AttendedReviewerTypes.Split('|', StringSplitOptions.RemoveEmptyEntries)
        .Select(s => Enum.Parse(typeof(AttendedReviewerType), s)).Cast<AttendedReviewerType>().ToList();

    public string AttendedReviewerTypes { get; set; } = string.Empty;

    [StringLength(1000)]
    public string TrialExtraConfigJsonStr { get; set; } = string.Empty;

    public bool VisitPlanConfirmed { get; set; }

    [Comment("受试者编号具体规则")]
    public string SubjectCodeRule { get; set; } = I18n.T("Trial_number");
    [Comment("是否 提醒受试者编号规则")]
    public bool IsNoticeSubjectCodeRule { get; set; } = true;

    [Comment("是否 有基准时间(首次给药时间)")]
    public bool IsHaveFirstGiveMedicineDate { get; set; } = true;

    [Comment("是否有  受试者年龄")]
    public bool IsHaveSubjectAge { get; set; } = false;
    [Comment("是否有 入组性确认")]
    public bool IsEnrollementQualificationConfirm { get; set; } = false;
    [Comment("出组后计划外访视名称")]
    public string OutEnrollmentVisitName { get; set; } = "EOT";
    [Comment("是否 验证拍片日期")]
    public bool IsVerifyVisitImageDate { get; set; } = true;
    [Comment("临床信息传输 1:系统录入  2:系统录入+PDF  0:无")]
    public int ClinicalInformationTransmissionEnum { get; set; } = 1;

    [Comment("是否审核 临床信息")]
    public bool IsCRAAuditClinicalInformation { get; set; } = false;

    [Comment("QC流程  0 不审,1 单审,2双审")]
    public TrialQCProcess QCProcessEnum { get; set; } = TrialQCProcess.DoubleAudit;

    [Comment("影像一致性核查")]
    public bool IsImageConsistencyVerification { get; set; } = true;

    [Comment("影像导出")]
    public bool IsImageExport { get; set; } = false;

    public bool IsSubjectSecondCodeView { get; set; }
    [Comment("阅片方式")]
    public int ReadingMode { get; set; } = 1;

    public int ChangeDefalutDays { get; set; } = 7;

    [Comment("跨项目复制")]
    public bool IsImageReplicationAcrossTrial { get; set; } = false;

    [MaxLength]
    public string BodyPartTypes { get; set; } = "鼻咽部|脑部|颈部|胸部|上/下腹部|盆腔|全身|其他";
    public string Modalitys { get; set; } = "CT|MRI";

    [NotMapped]
    public List<string> ModalityList => Modalitys.Split('|', StringSplitOptions.RemoveEmptyEntries).Where(t => !string.IsNullOrEmpty(t)).ToList();
    public string PreliminaryAuditReuploadText { get; set; } = string.Empty;

    public string ReviewAuditReuploadText { get; set; } = string.Empty;
    [Comment("PD 进展是否显示   配置访视 是否显示 PD进展 (从而可以设置状态)")]
    public bool IsPDProgressView { get; set; }

    [Comment("研究方案号")]
    public string ResearchProgramNo { get; set; } = string.Empty;

    [Comment("实验名称")]
    public string ExperimentName { get; set; } = string.Empty;

    [Comment("主研单位")]
    public string MainResearchUnit { get; set; } = string.Empty;

    [Comment("负责人PI")]
    public string HeadPI { get; set; } = string.Empty;

    public bool IsUrgent { get; set; }

    [Comment("项目类型 1 正式项目、0 非正式项目  2是培训项目")]
    public TrialType TrialType { get; set; }
    public int PlanSiteCount { get; set; }

    public int PlanVisitCount { get; set; }

    public DateTime? TrialFinishedTime { get; set; }

    public bool IsSubjectSexView { get; set; } = false;

    [Comment("配置Suject  Edit页面 是否显示 加急")]
    public bool IsSubjectExpeditedView { get; set; } = false;

    public bool IsTrialStart { get; set; } = false;
    [Comment("QC 问题流程")]
    public UserRole QCQuestionConfirmedUser { get; set; }
    public Guid? QCQuestionConfirmedUserId { get; set; }
    public DateTime? QCQuestionConfirmedTime { get; set; }

    [Comment("项目完成时间")]
    public DateTime? TrialFinishTime { get; set; }

    public int? DigitPlaces { get; set; } = 1;

    public bool IsTrialProcessConfirmed { get; set; }
    public bool IsTrialBasicLogicConfirmed { get; set; }
    public bool IsTrialUrgentConfirmed { get; set; }

    public bool IsQCQuestionConfirmed { get; set; }
    [Comment("同步临床数据时间")]
    public DateTime? SyncClinicalDataTime { get; set; }
    public string BlindBaseLineName { get; set; } = "Baseline";

    public string BlindFollowUpPrefix { get; set; } = "Follow-up";

    public int IndicationEnum { get; set; } = -1;

    public string VitrualSiteCode { get; set; } = string.Empty;

    #region 检查相关新加字段

    /// <summary>
    /// 是否显示检查名称
    /// </summary>
    public bool IsShowStudyName { get; set; } = false;

    /// <summary>
    /// 检查名称列表
    /// </summary>
    public List<StudyName> StudyNameList { get; set; } = new List<StudyName>();

    /// <summary>
    /// 图像格式
    /// </summary>
    [StringLength(2000)]
    public List<string> ImageFormatList { get; set; } = new List<string>() {"jpg","jpeg","png","bmp","pdf","zip" };
    #endregion

    #region 邮件配置
    [Comment("发件箱账号")]
    public string EmailFromEmail { get; set; } = string.Empty;

    [Comment("发件人")]
    public string EmailFromName { get; set; } = string.Empty;

    [Comment("密码/授权码")]
    public string EmailAuthorizationCode { get; set; } = string.Empty;

    [Comment("SMTP服务器")]
    public string EmailSMTPServerAddress { get; set; } = string.Empty;

    [Comment("SMTP端口")]
    public int EmailSMTPServerPort { get; set; }

    [Comment("是否配置过邮箱")]
    public bool IsConfigureEmail { get; set; } = false;
    #endregion
    public bool IsPACSConnect { get; set; }

    public bool IsTrialPACSConfirmed { get; set; }

    [Comment("项目术语配置Json字符串")]
    [StringLength(2000)]
    public List<TrialObjectNameConfig> TrialObjectNameList { get; set; }

    [Comment("SPM 参与中心调研")]
    public bool IsSPMJoinSiteSurvey { get; set; }

    [Comment("SPM 参与阅片人筛选")]
    public bool IsSPMJoinReviewerSelect { get; set; }

    [Comment("SPM 参与重阅审批")]
    public bool IsSPMJoinReReadingApproval { get; set; }

    [Comment("阅片任务产生之前 采集影像")]
    public CollectImagesType CollectImagesEnum { get; set; }

}

public enum CollectImagesType
{
    None = 0,

    Dicom = 1,

    NoneDicom = 2
}

/// <summary>
/// 检查名称
/// </summary>

[ComplexType]
public class StudyName
{
    /// <summary>
    /// 是否选中
    /// </summary>
    public bool IsChoose { get; set; }

    /// <summary>
    /// 名称
    /// </summary>
    public string Name { get; set; }

    /// <summary>
    /// 英文名称
    /// </summary>
    public string EnName { get; set; }
}

[ComplexType]
public class TrialObjectNameConfig
{
    public string Name { get; set; }

    public string TrialName { get; set; }

    public bool IsDefault { get; set; }
}