using IRaCIS.Application.Interfaces;
using IRaCIS.Application.Contracts;
using IRaCIS.Core.Domain.Share;
using EasyCaching.Core;
using IRaCIS.Core.Application.Filter;
using Microsoft.AspNetCore.Mvc;
using Panda.DynamicWebApi.Attributes;
using IRaCIS.Core.Infrastructure;
using Microsoft.Extensions.Options;
using static IRaCIS.Core.Domain.Share.StaticData;
using Microsoft.AspNetCore.Authorization;
using System.Linq.Expressions;
using System.Linq;

namespace IRaCIS.Application.Services
{

    [ApiExplorerSettings(GroupName = "Trial")]

    public class TrialService : BaseService, ITrialService
    {

        private readonly IEasyCachingProvider _provider;
        private readonly IRepository<Trial> _trialRepository;
        private readonly IRepository<TrialUser> _trialUserRepository;
        private readonly IOptionsMonitor<ServiceVerifyConfigOption> _verifyConfig;

        private readonly IOptionsMonitor<SystemEmailSendConfig> _systemEmailSendConfig;

        public bool TrialExpeditedChange { get; set; } = false;


        public TrialService(IEasyCachingProvider provider, IRepository<Trial> trialRepository,
            IRepository<TrialUser> trialUserRepository, IOptionsMonitor<ServiceVerifyConfigOption> verifyConfig
            , IOptionsMonitor<SystemEmailSendConfig> systemEmailSendConfig
            )
        {
            _systemEmailSendConfig = systemEmailSendConfig;
            _verifyConfig = verifyConfig;
            _provider = provider;
            _trialRepository = trialRepository;
            this._trialUserRepository = trialUserRepository;
        }

        /// <summary>
        /// 分页获取临床项目列表  默认后台加急状态为3 查所有的   
        /// </summary>
        /// <param name="searchParam"></param>
        /// <returns></returns>
        [HttpPost]
        public async Task<PageOutput<TrialDetailDTO>> GetTrialList(TrialQueryDTO searchParam)
        {

            var multiModalityIdSelectCount = searchParam.ModalityIds.Count;
            var multiCriteriaSelectCount = searchParam.CriterionIds.Count;
            var multiReviewTypeSelectCount = searchParam.ReviewTypeIds.Count;

            Expression<Func<Trial, bool>> trialDeclarationTypeExpression = x => true;



            foreach (var item in searchParam.DeclarationTypeEnumList)
            {
                trialDeclarationTypeExpression = trialDeclarationTypeExpression.And(t => t.DeclarationTypes.Contains($"|{item}|"));
            }

            Expression<Func<Trial, bool>> trialAttendedReviewerTypeExpression = x => true;

            foreach (var item in searchParam.AttendedReviewerTypeEnumList)
            {
                trialAttendedReviewerTypeExpression = trialAttendedReviewerTypeExpression.And(t => t.AttendedReviewerTypes.Contains($"|{item}|"));
            }


            var query = _trialRepository.AsQueryable().IgnoreQueryFilters()
                .WhereIf(!string.IsNullOrEmpty(searchParam.TrialStatusStr), o => o.TrialStatusStr.Contains(searchParam.TrialStatusStr))
                .WhereIf(searchParam.SponsorId != null, o => o.SponsorId == searchParam.SponsorId)
                .WhereIf(searchParam.Expedited != null, o => o.Expedited == searchParam.Expedited)
                .WhereIf(!string.IsNullOrEmpty(searchParam.Code), o => o.TrialCode.Contains(searchParam.Code))
                .WhereIf(!string.IsNullOrWhiteSpace(searchParam.Indication), o => o.Indication.Contains(searchParam.Indication))
                .WhereIf(!string.IsNullOrEmpty(searchParam.ResearchProgramNo), o => o.ResearchProgramNo.Contains(searchParam.ResearchProgramNo))
                .WhereIf(!string.IsNullOrWhiteSpace(searchParam.ExperimentName), o => o.ExperimentName.Contains(searchParam.ExperimentName))
                .WhereIf(searchParam.PhaseId != null, o => o.PhaseId == searchParam.PhaseId)

                .WhereIf(searchParam.DeclarationTypeEnumList.Count > 0, trialDeclarationTypeExpression)
                .WhereIf(searchParam.AttendedReviewerTypeEnumList.Count > 0, trialAttendedReviewerTypeExpression)

                //.WhereIf(searchParam.AttendedReviewerType != null, o => o.AttendedReviewerType == searchParam.AttendedReviewerType)

                .WhereIf(searchParam.IndicationTypeId != null, o => o.IndicationTypeId == searchParam.IndicationTypeId)
                .WhereIf(searchParam.CROId != null, o => o.CROId == searchParam.CROId)
                .WhereIf(searchParam.BeginDate != null, o => o.CreateTime >= searchParam.BeginDate)
                .WhereIf(searchParam.EndDate != null, o => o.CreateTime <= searchParam.EndDate)

                .WhereIf(multiModalityIdSelectCount > 0, t => t.TrialDicList.Count(t => t.KeyName == StaticData.Modality) == multiModalityIdSelectCount)
                .WhereIf(multiCriteriaSelectCount > 0, t => t.TrialDicList.Count(t => t.KeyName == StaticData.Criterion) == multiCriteriaSelectCount)
                .WhereIf(multiReviewTypeSelectCount > 0, t => t.TrialDicList.Count(t => t.KeyName == StaticData.ReviewType) == multiReviewTypeSelectCount)
                .WhereIf(_userInfo.UserTypeEnumInt != (int)UserTypeEnum.SuperAdmin, t => t.TrialUserList.Any(t => t.UserId == _userInfo.Id && t.IsDeleted == false) && t.IsDeleted == false)
                .ProjectTo<TrialDetailDTO>(_mapper.ConfigurationProvider, new { userTypeEnumInt = _userInfo.UserTypeEnumInt, userId = _userInfo.Id , isEn_Us= _userInfo.IsEn_Us });

            return await query.ToPagedListAsync(searchParam.PageIndex, searchParam.PageSize, string.IsNullOrWhiteSpace(searchParam.SortField) ? "CreateTime" : searchParam.SortField, searchParam.Asc);


        }

        //过滤废除的项目
        public async Task<List<TrialSelectDTO>> GetTrialSelect()
        {
            return await _trialRepository.AsQueryable().IgnoreQueryFilters()
                .WhereIf(_userInfo.UserTypeEnumInt != (int)UserTypeEnum.SuperAdmin, t => t.TrialUserList.Any(t => t.UserId == _userInfo.Id) && t.IsDeleted == false)

                .ProjectTo<TrialSelectDTO>(_mapper.ConfigurationProvider).ToListAsync();
        }



        /// <summary>
        /// 获取项目基本信息
        /// </summary>
        /// <param name="projectId"></param>
        /// <returns></returns>
        [HttpGet("{projectId:guid}")]
        public async Task<TrialDetailDTO> GetTrialInfoAndLockState(Guid projectId)
        {
            return (await _trialRepository.Where(o => o.Id == projectId).IgnoreQueryFilters().ProjectTo<TrialDetailDTO>(_mapper.ConfigurationProvider, new {isEn_Us = _userInfo.IsEn_Us }).FirstOrDefaultAsync()).IfNullThrowException();

        }


  

        [HttpGet("{trialId:guid}")]
        public async Task<TrialAndTrialStateVieModel> GetTrialInfoAndMaxTrialState(Guid trialId)
        {
            return new TrialAndTrialStateVieModel()
            {
                TrialView = await GetTrialInfoAndLockState(trialId),
             
            };
        }


        [HttpGet("{trialId:guid}")]
        public async Task<int> GetTrialExpeditedState(Guid trialId)
        {
            var trial = (await _trialRepository.FirstOrDefaultAsync(u => u.Id == trialId)).IfNullThrowException();

            return trial.Expedited;
        }



        /// <summary>
        /// 添加项目
        /// </summary>
        /// <param name="trialAddModel"></param>
        /// <returns></returns>
        [NonDynamicMethod]
        public virtual async Task<IResponseOutput<Trial>> AddOrUpdateTrial(TrialCommand trialAddModel)
        {



            //测试用户 只能创建非正式项目
            if (_userInfo.IsTestUser && trialAddModel.TrialType != TrialType.NoneOfficial)
            {
                //---测试用户 只能创建非正式项目
                throw new BusinessValidationFailedException(_localizer["Trial_TestUserCreateOnlyNonFormal"]);
            }

            if (trialAddModel.Id == Guid.Empty || trialAddModel.Id == null)
            {
                if (await _trialRepository.AnyAsync(u => u.TrialCode == trialAddModel.TrialCode))
                {
                    //---已经存在相同的项目编号。
                    throw new BusinessValidationFailedException(_localizer["Trial_DuplicateProjectNumber"]);
                }

                var dbMaxCode = await _trialRepository.Where(t => t.CreateTime.Year == DateTime.Now.Year && t.TrialType == trialAddModel.TrialType).Select(t => t.Code).DefaultIfEmpty().MaxAsync();

                var currentYearMaxCodeNext = dbMaxCode + 1;

                //var test = _trialRepository.Where(t => t.CreateTime.Year == DateTime.Now.Year + 1).Select(t => t.Code).DefaultIfEmpty(1).ToList();

                var trial = _mapper.Map<Trial>(trialAddModel);
                //trial.Id = NewId.NextGuid();
                var yearStr = DateTime.Now.Year.ToString();

                trial.Code = currentYearMaxCodeNext;
                trial.TrialCode = (trial.TrialType == TrialType.NoneOfficial ? "T0" : yearStr.Substring(yearStr.Length - 2)) + trial.TrialCode + currentYearMaxCodeNext.ToString("D3");


                trial.DeclarationTypes = $"|{string.Join('|', trialAddModel.DeclarationTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";
                trial.AttendedReviewerTypes = $"|{string.Join('|', trialAddModel.AttendedReviewerTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";

                //多选信息
                trialAddModel.ModalityIds.ForEach(modalityId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = modalityId, KeyName = StaticData.Modality, TrialId = trial.Id }));
                trialAddModel.CriterionIds.ForEach(criterionId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = criterionId, KeyName = StaticData.Criterion, TrialId = trial.Id }));
                trialAddModel.ReviewTypeIds.ForEach(ReviewTypeId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = ReviewTypeId, KeyName = StaticData.ReviewType, TrialId = trial.Id }));

                //添加项目后 项目状态变更为申请下载简历
                trial.TrialEnrollStatus = (int)TrialEnrollStatus.ChooseDoctor;
                //trial.TrialStatusStr = StaticData.TrialInitializing;

                //状态变更详细表
                trial.ClinicalTrialProjectDetails.Add(new TrialStatusDetail() { TrialId = trial.Id, TrialStatus = (int)TrialEnrollStatus.ChooseDoctor });

                trial = await _trialRepository.AddAsync(trial);

                //如果是PM， 则需要将该人员添加到 运维人员表
                //添加运维人员PM 
                await _repository.AddAsync(new TrialUser() { TrialId = trial.Id, UserId = _userInfo.Id, JoinTime = DateTime.Now });

             

                //添加访视
                await _repository.AddAsync(new VisitStage { TrialId = trial.Id, VisitNum = 0, BlindName = "B" + 0.ToString("D3"), VisitDay = 0, VisitName = "Baseline", IsBaseLine = true });
                await _repository.AddAsync(new VisitStage { TrialId = trial.Id, VisitNum = 1, BlindName = "B" + 10.ToString("D3"), VisitDay = 30, VisitName = "Visit 1" });

                //默认采用系统邮件

                trial.EmailAuthorizationCode = _systemEmailSendConfig.CurrentValue.AuthorizationCode;
                trial.EmailFromEmail = _systemEmailSendConfig.CurrentValue.FromEmail;
                trial.EmailFromName = _systemEmailSendConfig.CurrentValue.FromName;
                trial.EmailSMTPServerAddress = _systemEmailSendConfig.CurrentValue.Host;
                trial.EmailSMTPServerPort = _systemEmailSendConfig.CurrentValue.Port;
                trial.IsConfigureEmail = true;


                var success = await _repository.SaveChangesAsync();

                _provider.Set(trial.Id.ToString(), StaticData.TrialState.TrialInitializing, TimeSpan.FromDays(7));

                return ResponseOutput.Ok(trial);
            }
            else
            {
                var updateModel = trialAddModel;

                if (!await _repository.AnyAsync<Trial>(u => u.Id == trialAddModel.Id && (u.TrialStatusStr == StaticData.TrialState.TrialInitializing || u.TrialStatusStr == StaticData.TrialState.TrialOngoing)))
                {
                    //---项目状态只有处于：初始化或者进行中时，才允许操作。
                    throw new BusinessValidationFailedException(_localizer["Trial_InvalidProjectStatus"]);

                }
                // 判断项目Id 是否已经存在
                if (await _repository.AnyAsync<Trial>(u => u.TrialCode == updateModel.TrialCode && u.Id != updateModel.Id))
                {
                    //---已经存在相同的项目编号。
                    throw new BusinessValidationFailedException(_localizer["Trial_DuplicateProjectNumber"]);
                }



                var trial = await _repository.FirstOrDefaultAsync<Trial>(t => t.Id == updateModel.Id);


                //删除中间表  Title对应的记录
                await _repository.BatchDeleteAsync<TrialDictionary>(t => t.TrialId == updateModel.Id);

                //重新插入新的 Title记录

                updateModel.ModalityIds.ForEach(modalityId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = modalityId, KeyName = StaticData.Modality, TrialId = trial.Id }));
                updateModel.CriterionIds.ForEach(criterionId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = criterionId, KeyName = StaticData.Criterion, TrialId = trial.Id }));
                updateModel.ReviewTypeIds.ForEach(ReviewTypeId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = ReviewTypeId, KeyName = StaticData.ReviewType, TrialId = trial.Id }));


                if (updateModel.Expedited != trial.Expedited && updateModel.Expedited != null)
                {
                    TrialExpeditedChange = true;
                  
                }
                _mapper.Map(updateModel, trial);

                trial.DeclarationTypes = $"|{string.Join('|', updateModel.DeclarationTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";
                trial.AttendedReviewerTypes = $"|{string.Join('|', updateModel.AttendedReviewerTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";

                var success = await _repository.SaveChangesAsync();
                return ResponseOutput.Ok(trial);

            }
        }


    



        /// <summary> 真删除项目  方便清理测试数据 </summary>
        /// <param name="trialId">临床试验项目Id</param>
        [AllowAnonymous]
        [HttpDelete, Route("{trialId:guid}")]
        public async Task<IResponseOutput> DeleteTrial(Guid trialId)
        {

            if (_verifyConfig.CurrentValue.OpenTrialRelationDelete)
            {
         

                await _repository.BatchDeleteAsync<CheckChallengeDialog>(o => o.SubjectVisit.TrialId == trialId);
                await _repository.BatchDeleteAsync<ClinicalDataTrialSet>(o => o.TrialId == trialId);

                await _repository.BatchDeleteAsync<ClinicalQuestionAnswer>(o => o.ClinicalForm.TrialId == trialId);
                await _repository.BatchDeleteAsync<ClinicalQuestionAnswer>(o => o.ClinicalForm.TrialId == trialId);
                await _repository.BatchDeleteAsync<ClinicalForm>(o => o.TrialId == trialId);

                await _repository.BatchDeleteAsync<UserUploadFile>(o => o.TrialId == trialId);
                await _repository.BatchDeleteAsync<CriterionNidusSystem>(o => o.TrialReadingCriterion.TrialId == trialId);

                await _repository.BatchDeleteAsync<CriterionNidusTrial>(o => o.TrialReadingCriterion.TrialId == trialId);

                await _repository.BatchDeleteAsync<DataInspection>(o => o.TrialId == trialId);
                await _repository.BatchDeleteAsync<DicomStudy>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<StudyMonitor>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<DicomSeries>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<DicomInstance>(t => t.TrialId == trialId);
             
                await _repository.BatchDeleteAsync<NoneDicomStudyFile>(t => t.NoneDicomStudy.TrialId == trialId);
                await _repository.BatchDeleteAsync<NoneDicomStudy>(t => t.TrialId == trialId);

                await _repository.BatchDeleteAsync<OrganTrialInfo>(t => t.TrialId == trialId);

            

                await _repository.BatchDeleteAsync<PreviousHistory>(t => t.SubjectVisit.TrialId == trialId);
                await _repository.BatchDeleteAsync<PreviousOther>(t => t.SubjectVisit.TrialId == trialId);
                await _repository.BatchDeleteAsync<PreviousPDF>(t => t.SubjectVisit.TrialId == trialId);


                await _repository.BatchDeleteAsync<QCChallengeDialog>(t => t.QCChallenge.TrialId == trialId);
                await _repository.BatchDeleteAsync<QCChallenge>(t => t.TrialId == trialId);



                await _repository.BatchDeleteAsync<ReadingClinicalDataPDF>(t => t.ReadingClinicalData.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingClinicalData>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingGlobalTaskInfo>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingJudgeInfo>(t => t.TrialId == trialId);


                await _repository.BatchDeleteAsync<ReadingMedicalReviewDialog>(t => t.TaskMedicalReview.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingMedicineQuestionAnswer>(t => t.TaskMedicalReview.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingMedicineTrialQuestion>(t => t.TrialId == trialId);


                await _repository.BatchDeleteAsync<ReadingOncologyTaskInfo>(t => t.VisitTask.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingPeriodPlan>(t => t.ReadingPeriodSet.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingPeriodSet>(t => t.TrialId == trialId);


                await _repository.BatchDeleteAsync<ReadingQuestionTrial>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingTableAnswerRowInfo>(t => t.TrialId == trialId);

                await _repository.BatchDeleteAsync<ReadingTableQuestionAnswer>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingTableQuestionTrial>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingTaskQuestionAnswer>(t => t.TrialId == trialId);

                await _repository.BatchDeleteAsync<ReadingTaskRelation>(t => t.VisitTask.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadModule>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingTaskQuestionAnswer>(t => t.TrialId == trialId);

               

                await _repository.BatchDeleteAsync<Subject>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<SubjectVisit>(t => t.TrialId == trialId);

            
                await _repository.BatchDeleteAsync<TaskInfluence>(t => t.InfluenceTask.TrialId == trialId);
                await _repository.BatchDeleteAsync<TaskMedicalReview>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TaskMedicalReviewRule>(t => t.TrialId == trialId);

                await _repository.BatchDeleteAsync<TrialStateChange>(t => t.TrialId == trialId);
             


                await _repository.BatchDeleteAsync<Trial>(o => o.Id == trialId);
                await _repository.BatchDeleteAsync<TrialClinicalDataSetCriterion>(t => t.TrialReadingCriterion.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialCriterionDictionaryCode>(t => t.TrialReadingCriterion.TrialId == trialId);
                await _repository.BatchDeleteAsync<ReadingQuestionCriterionTrial>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialDictionary>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialDocConfirmedUser>(t => t.TrialDocument.TrialId == trialId);

                await _repository.BatchDeleteAsync<TrialDocument>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialDocNeedConfirmedUserType>(t => t.TrialDocument.TrialId == trialId);

                await _repository.BatchDeleteAsync<TrialEmailNoticeUser>(t => t.TrialEmailNoticeConfig.TrialId == trialId);

                //await _repository.BatchDeleteAsync<TrialExperience>(t => t.TrialId == trialId) ;
                await _repository.BatchDeleteAsync<TrialEmailNoticeUser>(t => t.TrialEmailNoticeConfig.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialEmailNoticeConfig>(t => t.TrialId == trialId);

                await _repository.BatchDeleteAsync<TrialExternalUser>(t => t.TrialId == trialId);


                await _repository.BatchDeleteAsync<TrialQCQuestion>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialQCQuestionAnswer>(t => t.TrialId == trialId);

                


                await _repository.BatchDeleteAsync<TrialSign>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialSite>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialSiteSurvey>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialSiteUserSurvey>(t => t.TrialSiteSurvey.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialSiteEquipmentSurvey>(t => t.TrialSiteSurvey.TrialId == trialId);

                await _repository.BatchDeleteAsync<TrialUser>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialSiteUser>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<VisitStage>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<VisitPlanInfluenceStat>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<VisitPlanInfluenceStudy>(t => t.TrialId == trialId);

                await _repository.BatchDeleteAsync<VisitTaskReReading>(t => t.OriginalReReadingTask.TrialId == trialId);
                await _repository.BatchDeleteAsync<VisitTask>(t => t.TrialId == trialId);
                await _repository.BatchDeleteAsync<TrialStateChange>(t => t.TrialId == trialId) ;

                return ResponseOutput.Ok();

            }

            else
            {
                //---当前运行环境下，不允许删除项目数据。
                return ResponseOutput.NotOk(_localizer["Trial_CannotDeleteProject"]);
            }


        }









        #region 医生用户接口



 

        #endregion






    }

}