292 lines
12 KiB
C#
292 lines
12 KiB
C#
using IRaCIS.Application.Interfaces;
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using IRaCIS.Application.Contracts;
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using IRaCIS.Core.Infra.EFCore;
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using IRaCIS.Core.Application.Filter;
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using IRaCIS.Core.Domain.Share;
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using Microsoft.AspNetCore.Mvc;
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using IRaCIS.Core.Application.Service.Inspection.Interface;
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using IRaCIS.Core.Infrastructure;
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using Newtonsoft.Json;
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using IRaCIS.Core.Domain.Common;
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namespace IRaCIS.Application.Services
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{
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[ApiExplorerSettings(GroupName = "Trial")]
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public class SubjectService : BaseService, ISubjectService
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{
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private readonly IRepository<Subject> _subjectRepository;
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private readonly IInspectionService _inspectionService;
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private readonly IRepository<SubjectVisit> _subjectVisitRepository;
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public SubjectService(IRepository<Subject> subjectRepository, IInspectionService inspectionService,IRepository<SubjectVisit> subjectVisitRepository)
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{
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_subjectRepository = subjectRepository;
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_inspectionService = inspectionService;
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_subjectVisitRepository = subjectVisitRepository;
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}
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/// <summary>
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/// 添加或更新受试者信息[New]
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/// </summary>
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/// <param name="subjectCommand">state:1-访视中，2-出组。0-全部</param>
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/// <returns></returns>
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[TrialAudit(AuditType.SubjectAudit, AuditOptType.AddOrUpdateSubject)]
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[TypeFilter(typeof(TrialResourceFilter))]
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public async Task<IResponseOutput<string>> AddOrUpdateSubject([FromBody] SubjectCommand subjectCommand)
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{
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var svlist = new List<SubjectVisit>();
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if (await _repository.AnyAsync<Trial>(t => t.Id == subjectCommand.TrialId && !t.VisitPlanConfirmed))
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{
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return ResponseOutput.NotOk("The trial visit plan has not been confirmed yet.Please contact the project manager to confirm the visit plan before adding subject.");
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}
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var verifyExp1 = new EntityVerifyExp<Subject>()
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{
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VerifyExp = u => u.Code == subjectCommand.Code && u.TrialId == subjectCommand.TrialId,
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VerifyMsg = "A subjects with the same subject ID already existed in this trial."
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};
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bool isadd = false;
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Subject mapedSubject = null;
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if (subjectCommand.Id == null) //insert
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{
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isadd = true;
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mapedSubject= await _subjectRepository.InsertFromDTOAsync(subjectCommand, false, verifyExp1);
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//添加受试者的时候，获取访视计划列表，添加到受试者访视表。
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var visitPlan = await _repository.Where<VisitStage>(t => t.TrialId == subjectCommand.TrialId).ToListAsync();
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svlist = _mapper.Map<List<SubjectVisit>>(visitPlan);
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var IsEnrollementQualificationConfirm = await _repository.Where<Trial>(t => t.Id == mapedSubject.TrialId).Select(u => u.IsEnrollementQualificationConfirm).FirstOrDefaultAsync();
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svlist.ForEach(t =>
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{
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t.SubjectId = mapedSubject.Id;
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t.TrialId = subjectCommand.TrialId;
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t.SiteId = subjectCommand.SiteId;
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t.IsEnrollmentConfirm = t.IsBaseLine ? IsEnrollementQualificationConfirm : false;
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});
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await _subjectVisitRepository.AddRangeAsync(svlist);
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}
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else //update
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{
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mapedSubject = await _subjectRepository.UpdateFromDTOAsync(subjectCommand, false,false, verifyExp1/*, verifyExp2*/);
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}
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await _repository.SaveChangesAsync();
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var createtime = DateTime.Now.AddSeconds(1);
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// 添加稽查记录
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if (isadd)
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{
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List<DataInspection> datas = new List<DataInspection>();
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// 移到仓储了
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//datas.Add(new DataInspection()
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//{
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// TrialId = subjectCommand.TrialId,
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// SiteId = subjectCommand.SiteId,
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// SubjectId = mapedSubject.Id,
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// SubjectCode = subjectCommand.Code,
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// IsSign=false,
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// CreateTime = createtime,
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// Identification = "Init|Subject|Status|Subject",
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// JsonDetail= JsonConvert.SerializeObject(new {
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// Status= "新增",
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// })
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//});
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JsonSerializerSettings settings = new JsonSerializerSettings();
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settings.PreserveReferencesHandling = PreserveReferencesHandling.Objects;
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settings.ReferenceLoopHandling = ReferenceLoopHandling.Serialize;
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//var jsonData = JsonConvert.SerializeObject(info, settings);
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var visittime = createtime.AddSeconds(1);
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foreach (var item in svlist)
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{
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// 添加访视
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datas.Add(new DataInspection()
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{
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TrialId = subjectCommand.TrialId,
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SiteId = subjectCommand.SiteId,
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SubjectId = mapedSubject.Id,
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SubjectCode = subjectCommand.Code,
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SubjectVisitId = item.Id,
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SubjectVisitName = item.VisitName,
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BlindName = item.BlindName,
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IsSign = false,
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CreateTime = visittime,
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Identification = "Add|Visit|Info|Visit-Image Upload",
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JsonDetail = item.ToJcJson()
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});
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// 初始化访视
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datas.Add(new DataInspection()
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{
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TrialId = subjectCommand.TrialId,
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SiteId = subjectCommand.SiteId,
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SubjectId = mapedSubject.Id,
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SubjectCode = subjectCommand.Code,
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SubjectVisitId = item.Id,
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BlindName = item.BlindName,
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SubjectVisitName = item.VisitName,
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IsSign = false,
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CreateTime = visittime.AddSeconds(1),
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Identification = "Init|Visit|Status|Visit-Image Upload",
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JsonDetail = item.ToJcJson()
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});
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}
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await _inspectionService.AddListInspectionRecordAsync(datas);
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}
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return ResponseOutput.Ok(mapedSubject.Id.ToString());
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}
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[HttpPut("{trialId:guid}")]
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[UnitOfWork]
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public async Task<IResponseOutput> UpdateSubjectStatus(SubjectStatusChangeCommand subjectStatusChangeCommand)
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{
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await _subjectRepository.UpdateFromDTOAsync(subjectStatusChangeCommand, true);
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return ResponseOutput.Ok();
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}
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[HttpDelete("{id:guid}/{trialId:guid}")]
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[TrialAudit(AuditType.SubjectAudit, AuditOptType.DeleteSubject)]
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[TypeFilter(typeof(TrialResourceFilter))]
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public async Task<IResponseOutput> DeleteSubject(Guid id)
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{
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if (await _subjectVisitRepository.AnyAsync(u => u.SubjectId == id && u.VisitExecuted == VisitExecutedEnum.Executed))
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{
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return ResponseOutput.NotOk("This subject has executed a visit with uploading study images,and couldn't be deleted.");
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}
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var isSuccess = await _subjectRepository.BatchDeleteNoTrackingAsync(u => u.Id == id);
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await _subjectVisitRepository.DeleteFromQueryAsync(u => u.SubjectId == id);
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var subvisit = await _subjectVisitRepository.Where(x => x.SubjectId == id).ToListAsync();
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List<DataInspection> datas = new List<DataInspection>();
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foreach (var item in subvisit)
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{
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datas.Add(new DataInspection()
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{
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SiteId = item.SiteId,
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SubjectId = item.SubjectId,
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TrialId = item.TrialId,
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SubjectVisitId = item.Id,
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Identification = "Delete|Visit|Data|Visit-Image Upload",
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JsonDetail = JsonConvert.SerializeObject(item)
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});
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};
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await _inspectionService.AddListInspectionRecordAsync(datas);
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return ResponseOutput.Result(isSuccess);
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}
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/// <summary> 分页获取受试者列表[New] </summary>
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/// /// <param name="param">state:1-访视中，2-出组。0-全部</param>
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[HttpPost]
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public async Task<IResponseOutput<PageOutput<SubjectQueryView>, TrialSubjectConfig>> GetSubjectList(SubjectQueryParam param)
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{
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var subjectQuery = _subjectRepository.Where(u => u.TrialId == param.TrialId)
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.WhereIf(!string.IsNullOrWhiteSpace(param.Code), t => t.Code.Contains(param.Code))
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.WhereIf(!string.IsNullOrWhiteSpace(param.Name), t => t.ShortName.Contains(param.Name))
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.WhereIf(!string.IsNullOrWhiteSpace(param.Sex), t => t.Sex.Contains(param.Sex))
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.WhereIf(param.Status != null, t => t.Status == param.Status)
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.WhereIf(param.SiteId != null, t => t.SiteId == param.SiteId)
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// CRC 只负责他管理site的受试者
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.WhereIf(_userInfo.UserTypeEnumInt == (int)UserTypeEnum.ClinicalResearchCoordinator, t => t.TrialSite.CRCUserList.Any(t => t.UserId == _userInfo.Id))
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.ProjectTo<SubjectQueryView>(_mapper.ConfigurationProvider);
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var pageList = await subjectQuery.ToPagedListAsync(param.PageIndex, param.PageSize, param.SortField == string.Empty ? "Code" : param.SortField, param.Asc);
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var trialConfig = await _repository.Where<Trial>(t => t.Id == param.TrialId).ProjectTo<TrialSubjectConfig>(_mapper.ConfigurationProvider).FirstOrDefaultAsync().IfNullThrowException();
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return ResponseOutput.Ok(pageList, trialConfig);
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}
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/// <summary>
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/// 计划外访视 获取受试者选择下拉框列表
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/// </summary>
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[HttpGet("{siteId:guid}/{trialId:guid}")]
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public List<SubjectSelect> GetSubjectListBySiteId(Guid siteId, Guid trialId)
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{
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var query = _subjectRepository.Where(t => t.SiteId == siteId && t.TrialId == trialId && t.Status == SubjectStatus.OnVisit).Select(u => new SubjectSelect()
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{
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Code = u.Code,
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FirstName = u.FirstName,
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LastName = u.LastName,
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Sex = u.Sex,
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SubjectId = u.Id,
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Age = u.Age,
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MRN = u.MedicalNo,
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Status = u.Status,
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FirstGiveMedicineTime = u.FirstGiveMedicineTime
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});
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return query.ToList();
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}
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[Obsolete]
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[HttpGet("{trialId:guid}/{subjectId:guid}/{finalSubjectVisitId:guid}")]
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public async Task<IResponseOutput> VerifySubjectFinalVisit(Guid subjectId, Guid finalSubjectVisitId)
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{
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if (await _repository.AnyAsync<SubjectVisit>(t => t.SubjectId == subjectId && t.IsFinalVisit))
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{
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return ResponseOutput.NotOk("该受试者已经有访视设置为末次访视，不允许将该访视设置为末次访视");
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}
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var sv = (await _repository.FirstOrDefaultAsync<SubjectVisit>(t => t.Id == finalSubjectVisitId)).IfNullThrowException();
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if (await _repository.AnyAsync<SubjectVisit>(t => t.SubjectId == subjectId && t.VisitNum > sv.VisitNum && t.SubmitState == SubmitStateEnum.ToSubmit))
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{
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return ResponseOutput.NotOk("该受试者此访视后有影像上传，该访视不允许设置为末次访视");
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}
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return ResponseOutput.Ok();
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}
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}
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}
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