670 lines
34 KiB
C#
670 lines
34 KiB
C#
using IRaCIS.Application.Contracts;
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using IRaCIS.Application.Interfaces;
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using IRaCIS.Core.Application.Filter;
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using IRaCIS.Core.Application.Helper;
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using IRaCIS.Core.Domain.Share;
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using IRaCIS.Core.Infrastructure;
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using Microsoft.AspNetCore.Authorization;
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using Microsoft.AspNetCore.Mvc;
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using Microsoft.Extensions.Options;
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using Panda.DynamicWebApi.Attributes;
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using ZiggyCreatures.Caching.Fusion;
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namespace IRaCIS.Core.Application.Service
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{
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[ApiExplorerSettings(GroupName = "Trial")]
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public class TrialService(IRepository<Trial> _trialRepository,
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IRepository<TrialUser> _trialUserRepository,
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IRepository<CRO> _croRepository,
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IRepository<EnrollDetail> _enrollDetailRepository,
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IRepository<Dictionary> _dictionaryRepository,
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IRepository<Enroll> _enrollRepository,
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IRepository<Workload> _workloadRepository,
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IRepository<Sponsor> _sponsorRepository,
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IRepository<VisitStage> _visitStageRepository,
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IRepository<TrialPaymentPrice> _trialPaymentPriceRepository,
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IRepository<TrialDictionary> _trialDictionaryRepository,
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IRepository<TrialBodyPart> _trialBodyPartRepository,
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IOptionsMonitor<ServiceVerifyConfigOption> _verifyConfig,
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IMapper _mapper, IUserInfo _userInfo, IStringLocalizer _localizer, IFusionCache _fusionCache) : BaseService, ITrialService
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{
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public bool TrialExpeditedChange { get; set; } = false;
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/// <summary>
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/// 分页获取临床项目列表 默认后台加急状态为3 查所有的
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/// </summary>
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/// <param name="inQuery"></param>
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/// <returns></returns>
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[HttpPost]
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public async Task<PageOutput<TrialDetailDTO>> GetTrialList(TrialQueryDTO inQuery)
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{
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var multiModalityIdSelectCount = inQuery.ModalityIds.Count;
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var multiCriteriaSelectCount = inQuery.CriterionIds.Count;
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var multiReviewTypeSelectCount = inQuery.ReviewTypeIds.Count;
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Expression<Func<Trial, bool>> trialDeclarationTypeExpression = x => true;
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foreach (var item in inQuery.DeclarationTypeEnumList)
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{
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trialDeclarationTypeExpression = trialDeclarationTypeExpression.And(t => t.DeclarationTypes.Contains($"|{item}|"));
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}
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Expression<Func<Trial, bool>> trialAttendedReviewerTypeExpression = x => true;
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foreach (var item in inQuery.AttendedReviewerTypeEnumList)
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{
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trialAttendedReviewerTypeExpression = trialAttendedReviewerTypeExpression.And(t => t.AttendedReviewerTypes.Contains($"|{item}|"));
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}
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var query = _trialRepository.AsQueryable()
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.WhereIf(!string.IsNullOrEmpty(inQuery.TrialStatusStr), o => o.TrialStatusStr.Contains(inQuery.TrialStatusStr))
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.WhereIf(inQuery.SponsorId != null, o => o.SponsorId == inQuery.SponsorId)
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.WhereIf(inQuery.Expedited != null, o => o.Expedited == inQuery.Expedited)
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.WhereIf(!string.IsNullOrEmpty(inQuery.Code), o => o.TrialCode.Contains(inQuery.Code))
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.WhereIf(!string.IsNullOrWhiteSpace(inQuery.Indication), o => o.Indication.Contains(inQuery.Indication))
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.WhereIf(!string.IsNullOrEmpty(inQuery.ResearchProgramNo), o => o.ResearchProgramNo.Contains(inQuery.ResearchProgramNo))
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.WhereIf(!string.IsNullOrWhiteSpace(inQuery.ExperimentName), o => o.ExperimentName.Contains(inQuery.ExperimentName))
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.WhereIf(inQuery.PhaseId != null, o => o.PhaseId == inQuery.PhaseId)
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.WhereIf(inQuery.DeclarationTypeEnumList.Count > 0, trialDeclarationTypeExpression)
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.WhereIf(inQuery.AttendedReviewerTypeEnumList.Count > 0, trialAttendedReviewerTypeExpression)
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//.WhereIf(searchParam.AttendedReviewerType != null, o => o.AttendedReviewerType == searchParam.AttendedReviewerType)
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.WhereIf(inQuery.IndicationTypeId != null, o => o.IndicationTypeId == inQuery.IndicationTypeId)
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.WhereIf(inQuery.CROId != null, o => o.CROId == inQuery.CROId)
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.WhereIf(inQuery.BeginDate != null, o => o.CreateTime >= inQuery.BeginDate)
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.WhereIf(inQuery.EndDate != null, o => o.CreateTime <= inQuery.EndDate)
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.WhereIf(multiModalityIdSelectCount > 0, t => t.TrialDicList.Count(t => t.KeyName == StaticData.Modality) == multiModalityIdSelectCount)
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.WhereIf(multiCriteriaSelectCount > 0, t => t.TrialDicList.Count(t => t.KeyName == StaticData.Criterion) == multiCriteriaSelectCount)
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.WhereIf(multiReviewTypeSelectCount > 0, t => t.TrialDicList.Count(t => t.KeyName == StaticData.ReviewType) == multiReviewTypeSelectCount)
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.WhereIf(_userInfo.UserTypeEnumInt != (int)UserTypeEnum.SuperAdmin, t => t.TrialUserList.Any(t => t.UserId == _userInfo.Id && t.IsDeleted == false) && t.IsDeleted == false)
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.ProjectTo<TrialDetailDTO>(_mapper.ConfigurationProvider, new { userTypeEnumInt = _userInfo.UserTypeEnumInt, userId = _userInfo.Id, isEn_Us = _userInfo.IsEn_Us });
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return await query.ToPagedListAsync(inQuery);
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}
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//过滤废除的项目
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public async Task<List<TrialSelectDTO>> GetTrialSelect()
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{
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return await _trialRepository.AsQueryable()
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.WhereIf(_userInfo.UserTypeEnumInt != (int)UserTypeEnum.SuperAdmin && _userInfo.UserTypeEnumInt != (int)UserTypeEnum.Admin && _userInfo.UserTypeEnumInt != (int)UserTypeEnum.OP, t => t.TrialUserList.Any(t => t.UserId == _userInfo.Id) && t.IsDeleted == false)
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.ProjectTo<TrialSelectDTO>(_mapper.ConfigurationProvider).ToListAsync();
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}
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/// <summary>
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/// 获取项目基本信息
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/// </summary>
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/// <param name="projectId"></param>
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/// <returns></returns>
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[HttpGet("{projectId:guid}")]
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public async Task<TrialDetailDTO> GetTrialInfoAndLockState(Guid projectId)
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{
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return (await _trialRepository.Where(o => o.Id == projectId).ProjectTo<TrialDetailDTO>(_mapper.ConfigurationProvider, new { isEn_Us = _userInfo.IsEn_Us }).FirstOrDefaultAsync()).IfNullThrowException();
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}
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[NonDynamicMethod]
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public async Task<int> GetTrialMaxState(Guid trialId)
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{
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return await _enrollDetailRepository.Where(t => t.TrialId == trialId).MaxAsync(u => (int?)u.EnrollStatus) ?? 0;
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}
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[HttpGet("{trialId:guid}")]
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public async Task<TrialAndTrialStateVieModel> GetTrialInfoAndMaxTrialState(Guid trialId)
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{
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return new TrialAndTrialStateVieModel()
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{
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TrialView = await GetTrialInfoAndLockState(trialId),
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TrialMaxState = await GetTrialMaxState(trialId)
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};
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}
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[HttpGet("{trialId:guid}")]
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public async Task<int> GetTrialExpeditedState(Guid trialId)
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{
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var trial = (await _trialRepository.FirstOrDefaultAsync(u => u.Id == trialId)).IfNullThrowException();
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return trial.Expedited;
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}
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/// <summary>
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/// 添加项目
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/// </summary>
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/// <param name="trialAddModel"></param>
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/// <returns></returns>
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[NonDynamicMethod]
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public virtual async Task<IResponseOutput<Trial>> AddOrUpdateTrial(TrialCommand trialAddModel)
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{
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//测试用户 只能创建非正式项目
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if (_userInfo.IsTestUser && trialAddModel.TrialType != TrialType.NoneOfficial)
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{
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//---测试用户 只能创建非正式项目
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throw new BusinessValidationFailedException(_localizer["Trial_TestUserCreateOnlyNonFormal"]);
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}
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if (trialAddModel.Id == Guid.Empty || trialAddModel.Id == null)
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{
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if (await _trialRepository.AnyAsync(u => u.TrialCode == trialAddModel.TrialCode))
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{
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//---已经存在相同的项目编号。
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throw new BusinessValidationFailedException(_localizer["Trial_DuplicateProjectNumber"]);
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}
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var dbMaxCode = await _trialRepository.Where(t => t.CreateTime.Year == DateTime.Now.Year && t.TrialType == trialAddModel.TrialType).Select(t => t.Code).DefaultIfEmpty().MaxAsync();
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var currentYearMaxCodeNext = dbMaxCode + 1;
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//var test = _trialRepository.Where(t => t.CreateTime.Year == DateTime.Now.Year + 1).Select(t => t.Code).DefaultIfEmpty(1).ToList();
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var trial = _mapper.Map<Trial>(trialAddModel);
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//trial.Id = NewId.NextGuid();
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var yearStr = DateTime.Now.Year.ToString();
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trial.Code = currentYearMaxCodeNext;
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trial.TrialCode = (trial.TrialType == TrialType.NoneOfficial ? "T0" : yearStr.Substring(yearStr.Length - 2)) + trial.TrialCode + currentYearMaxCodeNext.ToString("D3");
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trial.DeclarationTypes = $"|{string.Join('|', trialAddModel.DeclarationTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";
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trial.AttendedReviewerTypes = $"|{string.Join('|', trialAddModel.AttendedReviewerTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";
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//多选信息
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trialAddModel.ModalityIds.ForEach(modalityId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = modalityId, KeyName = StaticData.Modality, TrialId = trial.Id }));
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trialAddModel.CriterionIds.ForEach(criterionId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = criterionId, KeyName = StaticData.Criterion, TrialId = trial.Id }));
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trialAddModel.ReviewTypeIds.ForEach(ReviewTypeId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = ReviewTypeId, KeyName = StaticData.ReviewType, TrialId = trial.Id }));
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//添加项目后 项目状态变更为申请下载简历
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trial.TrialEnrollStatus = (int)TrialEnrollStatus.ChooseDoctor;
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//trial.TrialStatusStr = StaticData.TrialInitializing;
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//状态变更详细表
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trial.ClinicalTrialProjectDetails.Add(new TrialStatusDetail() { TrialId = trial.Id, TrialStatus = (int)TrialEnrollStatus.ChooseDoctor });
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trial = await _trialRepository.AddAsync(trial);
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//如果是PM， 则需要将该人员添加到 运维人员表
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//添加运维人员PM
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await _trialUserRepository.AddAsync(new TrialUser() { TrialId = trial.Id, UserId = _userInfo.Id, JoinTime = DateTime.Now });
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// 添加扩展信息表记录
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await _trialPaymentPriceRepository.AddAsync(new TrialPaymentPrice() { TrialId = trial.Id });
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//添加访视
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await _visitStageRepository.AddAsync(new VisitStage { TrialId = trial.Id, VisitNum = 0, BlindName = "B" + 0.ToString("D3"), VisitDay = 0, VisitName = "Baseline", IsBaseLine = true, VisitWindowLeft = -28, VisitWindowRight = 0 });
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await _visitStageRepository.AddAsync(new VisitStage { TrialId = trial.Id, VisitNum = 1, BlindName = "B" + 10.ToString("D3"), VisitDay = 30, VisitName = "Visit 1", VisitWindowLeft = -5, VisitWindowRight = 5 });
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var success = await _trialRepository.SaveChangesAsync();
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//维护CRO Sponsor
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await DealSponsorAndCROAsync(trial);
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//维护部位到项目表
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var searchList = await _dictionaryRepository.Where(t => t.Parent.Code == "BodyPart" && t.ParentId != null && t.IsEnable).ProjectTo<BasicDicSelect>(_mapper.ConfigurationProvider).ToListAsync();
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var needAddBodyPartList = searchList.Select(t => new TrialBodyPart() { Code = t.Code, Name = t.Value, NameCN = t.ValueCN }).ToList();
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foreach (var item in needAddBodyPartList)
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{
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item.TrialId = trial.Id;
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}
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await _trialBodyPartRepository.AddRangeAsync(needAddBodyPartList, true);
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await _fusionCache.SetAsync(CacheKeys.Trial(trial.Id.ToString()), StaticData.TrialState.TrialInitializing, TimeSpan.FromDays(7));
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return ResponseOutput.Ok(trial);
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}
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else
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{
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var updateModel = trialAddModel;
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if (!await _trialRepository.AnyAsync(u => u.Id == trialAddModel.Id && (u.TrialStatusStr == StaticData.TrialState.TrialInitializing || u.TrialStatusStr == StaticData.TrialState.TrialOngoing)))
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{
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//---项目状态只有处于：初始化或者进行中时，才允许操作。
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throw new BusinessValidationFailedException(_localizer["Trial_InvalidProjectStatus"]);
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}
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// 判断项目Id 是否已经存在
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if (await _trialRepository.AnyAsync(u => u.TrialCode == updateModel.TrialCode && u.Id != updateModel.Id))
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{
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//---已经存在相同的项目编号。
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throw new BusinessValidationFailedException(_localizer["Trial_DuplicateProjectNumber"]);
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}
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var trial = await _trialRepository.FirstOrDefaultAsync(t => t.Id == updateModel.Id);
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//删除中间表 Title对应的记录
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await _trialDictionaryRepository.BatchDeleteNoTrackingAsync(t => t.TrialId == updateModel.Id);
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//重新插入新的 Title记录
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updateModel.ModalityIds.ForEach(modalityId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = modalityId, KeyName = StaticData.Modality, TrialId = trial.Id }));
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updateModel.CriterionIds.ForEach(criterionId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = criterionId, KeyName = StaticData.Criterion, TrialId = trial.Id }));
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updateModel.ReviewTypeIds.ForEach(ReviewTypeId => trial.TrialDicList.Add(new TrialDictionary() { DictionaryId = ReviewTypeId, KeyName = StaticData.ReviewType, TrialId = trial.Id }));
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if (updateModel.Expedited != trial.Expedited && updateModel.Expedited != null)
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{
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TrialExpeditedChange = true;
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await TrialExpeditedStatusChange(trial.Id, trial.Expedited, (int)updateModel.Expedited);
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}
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_mapper.Map(updateModel, trial);
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trial.DeclarationTypes = $"|{string.Join('|', updateModel.DeclarationTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";
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trial.AttendedReviewerTypes = $"|{string.Join('|', updateModel.AttendedReviewerTypeEnumList.Select(x => ((int)x).ToString()).ToList())}|";
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var success = await _trialRepository.SaveChangesAsync();
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//维护CRO Sponsor
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await DealSponsorAndCROAsync(trial);
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return ResponseOutput.Ok(trial);
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}
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}
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private async Task DealSponsorAndCROAsync(Trial trial)
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{
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if (trial.SponsorId != null)
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{
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if (await _sponsorRepository.AnyAsync(t => t.Id == trial.SponsorId && t.IsTrialLevel))
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{
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await _sponsorRepository.BatchUpdateNoTrackingAsync(t => t.Id == trial.SponsorId, u => new Sponsor() { TrialId = trial.Id });
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}
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}
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if (trial.CROId != null)
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{
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if (await _croRepository.AnyAsync(t => t.Id == trial.CROId && t.IsTrialLevel))
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{
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await _croRepository.BatchUpdateNoTrackingAsync(t => t.Id == trial.CROId, u => new CRO() { TrialId = trial.Id });
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}
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}
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}
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// TODO: 需要优化，嵌套两层 switch case ？
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[NonDynamicMethod]
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private async Task TrialExpeditedStatusChange(Guid trialId, int oldState, int newState)
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{
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switch (oldState)
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{
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case (int)TrialExpedited.None:
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switch (newState)
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{
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case (int)TrialExpedited.ExpeditedIn24H:
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await _workloadRepository.BatchUpdateNoTrackingAsync(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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{
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TimepointIn24H = u.Timepoint,
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AdjudicationIn24H = u.Adjudication,
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Timepoint = 0,
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Adjudication = 0
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});
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break;
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case (int)TrialExpedited.ExpeditedIn48H:
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await _workloadRepository.BatchUpdateNoTrackingAsync(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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{
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TimepointIn48H = u.Timepoint,
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AdjudicationIn48H = u.Adjudication,
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Timepoint = 0,
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Adjudication = 0
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});
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break;
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}
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//_workloadRepository.Update(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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//{
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// Timepoint = 0,
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// Adjudication = 0
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//});
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break;
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case (int)TrialExpedited.ExpeditedIn24H:
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switch (newState)
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{
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case (int)TrialExpedited.None:
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await _workloadRepository.BatchUpdateNoTrackingAsync(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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{
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Timepoint = u.TimepointIn24H,
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Adjudication = u.AdjudicationIn24H,
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TimepointIn24H = 0,
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AdjudicationIn24H = 0
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});
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break;
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case (int)TrialExpedited.ExpeditedIn48H:
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await _workloadRepository.BatchUpdateNoTrackingAsync(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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{
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TimepointIn48H = u.TimepointIn24H,
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AdjudicationIn48H = u.AdjudicationIn24H,
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TimepointIn24H = 0,
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AdjudicationIn24H = 0
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});
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break;
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}
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//_workloadRepository.Update(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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//{
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// TimepointIn24H = 0,
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// AdjudicationIn24H = 0
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//});
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break;
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case (int)TrialExpedited.ExpeditedIn48H:
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switch (newState)
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{
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case (int)TrialExpedited.None:
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await _workloadRepository.BatchUpdateNoTrackingAsync(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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{
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Timepoint = u.TimepointIn48H,
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Adjudication = u.AdjudicationIn48H,
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TimepointIn48H = 0,
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AdjudicationIn48H = 0
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});
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break;
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case (int)TrialExpedited.ExpeditedIn24H:
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await _workloadRepository.BatchUpdateNoTrackingAsync(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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{
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TimepointIn24H = u.TimepointIn48H,
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AdjudicationIn24H = u.AdjudicationIn48H,
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TimepointIn48H = 0,
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AdjudicationIn48H = 0
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});
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break;
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}
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//_workloadRepository.Update(t => t.IsLock == false && t.TrialId == trialId, u => new Workload()
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//{
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// TimepointIn48H = 0,
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// AdjudicationIn48H = 0
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//});
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break;
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}
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}
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/// <summary>
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/// 标记项目删除
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/// </summary>
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/// <param name="trialId"></param>
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/// <returns></returns>
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[HttpDelete, Route("{trialId:guid}")]
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public async Task<IResponseOutput> MarkTrialDelete(Guid trialId)
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{
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await _trialRepository.BatchUpdateNoTrackingAsync(t => t.Id == trialId, u => new Trial() { IsDeleted = true });
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return ResponseOutput.Ok();
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}
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/// <summary> 真删除项目 方便清理测试数据 </summary>
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/// <param name="trialId">临床试验项目Id</param>
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[AllowAnonymous]
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[HttpDelete, Route("{trialId:guid}")]
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||
public async Task<IResponseOutput> DeleteTrial(Guid trialId, [FromServices] IRepository _repository)
|
||
{
|
||
|
||
|
||
var trial = (await _trialRepository.FirstOrDefaultAsync(u => u.Id == trialId, true)).IfNullThrowException();
|
||
|
||
|
||
if (_verifyConfig.CurrentValue.OpenTrialRelationDelete)
|
||
{
|
||
|
||
|
||
#region 真项目删除
|
||
await _repository.BatchDeleteNoTrackingAsync<CheckChallengeDialog>(o => o.SubjectVisit.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ClinicalDataTrialSet>(o => o.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<InspectionFile>(o => o.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<CriterionNidusSystem>(o => o.TrialReadingCriterion.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<DataInspection>(o => o.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<DicomStudy>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<StudyMonitor>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<DicomSeries>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<DicomInstance>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<EnrollReadingCategory>(t => t.Enroll.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<Enroll>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<EnrollDetail>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<NoneDicomStudyFile>(t => t.NoneDicomStudy.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<NoneDicomStudy>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<OrganTrialInfo>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<PaymentAdjustment>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<PaymentDetail>(t => t.TrialId == trialId);
|
||
|
||
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<PreviousHistory>(t => t.SubjectVisit.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<PreviousOther>(t => t.SubjectVisit.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<PreviousPDF>(t => t.SubjectVisit.TrialId == trialId);
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<QCChallengeDialog>(t => t.QCChallenge.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<QCChallenge>(t => t.TrialId == trialId);
|
||
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingClinicalDataPDF>(t => t.ReadingClinicalData.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingClinicalData>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingGlobalTaskInfo>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingJudgeInfo>(t => t.TrialId == trialId);
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingMedicalReviewDialog>(t => t.TaskMedicalReview.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingMedicineQuestionAnswer>(t => t.TaskMedicalReview.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingMedicineTrialQuestion>(t => t.TrialId == trialId);
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingOncologyTaskInfo>(t => t.VisitTask.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingPeriodPlan>(t => t.ReadingPeriodSet.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingPeriodSet>(t => t.TrialId == trialId);
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingQuestionTrial>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingTableAnswerRowInfo>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingTableQuestionAnswer>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingTableQuestionTrial>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingTaskQuestionAnswer>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingTaskRelation>(t => t.VisitTask.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadModule>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingTaskQuestionAnswer>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<SubjectCanceDoctor>(t => t.Subject.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<SubjectUser>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<Subject>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<SubjectVisit>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TaskAllocationRule>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TaskConsistentRule>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TaskInfluence>(t => t.InfluenceTask.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TaskMedicalReview>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TaskMedicalReviewRule>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialStateChange>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialPaymentPrice>(t => t.TrialId == trialId);
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<Trial>(o => o.Id == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialClinicalDataSetCriterion>(t => t.TrialReadingCriterion.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialCriterionDictionaryCode>(t => t.TrialReadingCriterion.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<ReadingQuestionCriterionTrial>(t => t.TrialId == trialId);
|
||
await _trialDictionaryRepository.BatchDeleteNoTrackingAsync(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialDocConfirmedUser>(t => t.TrialDocument.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialDocument>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialDocNeedConfirmedUserType>(t => t.TrialDocument.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialEmailNoticeUser>(t => t.TrialEmailNoticeConfig.TrialId == trialId);
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialEmailNoticeConfig>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialExternalUser>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialPaymentPrice>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialQCQuestion>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialQCQuestionAnswer>(t => t.TrialId == trialId);
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialRevenuesPrice>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialRevenuesPriceVerification>(t => t.TrialId == trialId);
|
||
|
||
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialSign>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialSite>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialSiteSurvey>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialSiteUserSurvey>(t => t.TrialSiteSurvey.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialSiteEquipmentSurvey>(t => t.TrialSiteSurvey.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialUser>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialSiteUser>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<VisitStage>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<VisitPlanInfluenceStat>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<VisitPlanInfluenceStudy>(t => t.TrialId == trialId);
|
||
|
||
await _repository.BatchDeleteNoTrackingAsync<VisitTaskReReading>(t => t.OriginalReReadingTask.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<VisitTask>(t => t.TrialId == trialId);
|
||
await _repository.BatchDeleteNoTrackingAsync<TrialStateChange>(t => t.TrialId == trialId);
|
||
#endregion
|
||
|
||
|
||
|
||
|
||
return ResponseOutput.Ok();
|
||
|
||
}
|
||
|
||
else
|
||
{
|
||
//---当前运行环境下，不允许删除项目数据。
|
||
return ResponseOutput.NotOk(_localizer["Trial_CannotDeleteProject"]);
|
||
}
|
||
|
||
|
||
}
|
||
|
||
|
||
|
||
[HttpPost]
|
||
public async Task<PageOutput<TrialDetailDTO>> GetReviewerTrialListByEnrollmentStatus(TrialByStatusQueryDTO inQuery)
|
||
{
|
||
|
||
var query = _trialRepository.AsQueryable()
|
||
.WhereIf(inQuery.Status == 5, t => t.EnrollList.Any(u => u.EnrollStatus == EnrollStatus.HasCommittedToCRO))
|
||
.WhereIf(inQuery.Status == 8, t => t.EnrollList.Any(u => u.EnrollStatus == EnrollStatus.InviteIntoGroup))
|
||
.WhereIf(inQuery.Status == 10, t => t.EnrollList.Any(u => u.EnrollStatus == EnrollStatus.DoctorReading))
|
||
.WhereIf(inQuery.Status == 14, t => t.EnrollList.Any(u => u.EnrollStatus == EnrollStatus.Finished))
|
||
.ProjectTo<TrialDetailDTO>(_mapper.ConfigurationProvider, new { userTypeEnumInt = _userInfo.UserTypeEnumInt, userId = _userInfo.Id, isEn_Us = _userInfo.IsEn_Us });
|
||
|
||
return await query.ToPagedListAsync(inQuery, nameof(TrialDetailDTO.CreateTime));
|
||
|
||
}
|
||
|
||
|
||
|
||
/// <summary>
|
||
/// 根据项目Id 获取医生Id，用于触发计算费用
|
||
/// </summary>
|
||
public async Task<List<Guid>> GetTrialEnrollmentReviewerIds(Guid trialId)
|
||
{
|
||
return await _enrollRepository.Where(u => u.TrialId == trialId &&
|
||
u.EnrollStatus >= EnrollStatus.DoctorReading).Select(u => u.DoctorId).Distinct().ToListAsync();
|
||
}
|
||
|
||
|
||
|
||
|
||
#region 医生用户接口
|
||
|
||
/// <summary> 分页获取医生参与的临床实验项目列表（查询条件）</summary>
|
||
/// <returns></returns>
|
||
[HttpPost]
|
||
public async Task<PageOutput<TrialDetailDTO>> GetTrialListByReviewer(ReviewerTrialQueryDTO inQuery)
|
||
{
|
||
var query = _trialRepository
|
||
.WhereIf(inQuery.EnrollStatus != null, o => (int)inQuery.EnrollStatus! == 10 ?
|
||
o.EnrollList.Any(o => o.EnrollStatus >= EnrollStatus.ConfirmIntoGroup && o.EnrollStatus <= EnrollStatus.DoctorReading && o.DoctorId == _userInfo.Id) :
|
||
o.EnrollList.Any(o => o.EnrollStatus == inQuery.EnrollStatus && o.DoctorId == _userInfo.Id))
|
||
.WhereIf(inQuery.Expedited != null, o => o.Expedited == inQuery.Expedited)
|
||
.WhereIf(!string.IsNullOrEmpty(inQuery.Code), o => o.TrialCode.Contains(inQuery.Code))
|
||
.WhereIf(!string.IsNullOrWhiteSpace(inQuery.Indication), o => o.Indication.Contains(inQuery.Indication))
|
||
.WhereIf(_userInfo.UserTypeEnumInt != (int)UserTypeEnum.SuperAdmin, t => t.TrialUserList.Any(t => t.UserId == _userInfo.Id))
|
||
.ProjectTo<TrialDetailDTO>(_mapper.ConfigurationProvider, new { userTypeEnumInt = _userInfo.UserTypeEnumInt, userId = _userInfo.Id, isEn_Us = _userInfo.IsEn_Us });
|
||
|
||
|
||
return await query.ToPagedListAsync(inQuery, nameof(TrialDetailDTO.CreateTime));
|
||
|
||
|
||
|
||
}
|
||
|
||
|
||
/// <summary>
|
||
/// 医生确认入组或拒绝入组
|
||
/// </summary>
|
||
/// <param name="trialId">项目Id</param>
|
||
/// <param name="status">9-拒绝入组，10-确认入组</param>
|
||
/// <returns></returns>
|
||
[HttpPost("{trialId:guid}/{status:int}")]
|
||
|
||
[TrialGlobalLimit("AfterStopCannNotOpt")]
|
||
public async Task<IResponseOutput> UpdateEnrollStatus(Guid trialId, EnrollStatus status)
|
||
{
|
||
await _enrollDetailRepository.AddAsync(new EnrollDetail()
|
||
{
|
||
DoctorId = _userInfo.Id,
|
||
TrialId = trialId,
|
||
EnrollStatus = status,
|
||
OptUserType = (int)SystemUserType.DoctorUser,
|
||
});
|
||
return ResponseOutput.Result(await _enrollRepository.BatchUpdateNoTrackingAsync(u => u.TrialId == trialId && u.DoctorId == _userInfo.Id, e => new Enroll
|
||
{
|
||
EnrollStatus = status
|
||
}));
|
||
}
|
||
|
||
#endregion
|
||
|
||
|
||
|
||
|
||
|
||
|
||
}
|
||
|
||
}
|