diff --git a/src/utils/extractPositioningFromDataset.js b/src/utils/extractPositioningFromDataset.js
new file mode 100644
index 00000000..f5bfc02a
--- /dev/null
+++ b/src/utils/extractPositioningFromDataset.js
@@ -0,0 +1,343 @@
+import getNumberValues from "./getNumberValues";
+import isNMReconstructable from "./isNMReconstructable";
+
+/**
+ * Get a subpart of Image Type dicom tag defined by index
+ * @param {*} dataSet
+ * @param {*} index 0 based index of the subtype
+ */
+function getImageTypeSubItemFromDataset(dataSet, index) {
+  const imageType = dataSet.string("x00080008");
+
+  if (imageType) {
+    const subTypes = imageType.split("\\");
+
+    if (subTypes.length > index) {
+      return subTypes[index];
+    }
+  }
+
+  return undefined;
+}
+// DICOM 标准中针对 Enhanced CT/MR/PET 等“增强型多帧”（Enhanced Multi-frame）影像， 强制要求为每一帧显式记录真实的独立空间坐标 。
+
+// - 它们的数据通常存放在： Per-frame Functional Groups Sequence (5200,9230) -> 对应的 Frame Item -> Plane Position Sequence (0020,9113) -> ImagePositionPatient (0020,0032) 。
+function getSharedFunctionalGroupsDataSet(dataSet) {
+  const seq = dataSet?.elements?.x52009229;
+  if (!seq?.items?.length) {
+    return;
+  }
+  return seq.items[0].dataSet;
+}
+
+function getPerFrameFunctionalGroupsDataSet(dataSet, frameIndex) {
+  const seq = dataSet?.elements?.x52009230;
+  if (!seq?.items?.length) {
+    return;
+  }
+  if (
+    !Number.isInteger(frameIndex) ||
+    frameIndex < 0 ||
+    frameIndex >= seq.items.length
+  ) {
+    return;
+  }
+  return seq.items[frameIndex].dataSet;
+}
+
+function getOrientationFromPlaneOrientationSequence(dataSet) {
+  const seq = dataSet?.elements?.x00209116;
+  if (!seq?.items?.length) {
+    return;
+  }
+  return getNumberValues(seq.items[0].dataSet, "x00200037", 6);
+}
+
+function getPositionFromPlanePositionSequence(dataSet) {
+  const seq = dataSet?.elements?.x00209113;
+  if (!seq?.items?.length) {
+    return;
+  }
+  return getNumberValues(seq.items[0].dataSet, "x00200032", 3);
+}
+
+function getPixelSpacingFromPixelMeasuresSequence(dataSet) {
+  const seq = dataSet?.elements?.x00289110;
+  if (!seq?.items?.length) {
+    return;
+  }
+  return getNumberValues(seq.items[0].dataSet, "x00280030", 2);
+}
+
+function getSliceThicknessFromPixelMeasuresSequence(dataSet) {
+  const seq = dataSet?.elements?.x00289110;
+  if (!seq?.items?.length) {
+    return;
+  }
+  if (!seq.items[0]?.dataSet?.elements?.x00180050) {
+    return;
+  }
+  return seq.items[0].dataSet.floatString("x00180050");
+}
+
+/**
+ * Extracts the orientation from NM multiframe dataset, if image type
+ * equal to RECON TOMO or RECON GATED TOMO
+ * @param {*} dataSet
+ * @returns
+ */
+function extractOrientationFromNMMultiframeDataset(dataSet) {
+  let imageOrientationPatient;
+  const modality = dataSet.string("x00080060");
+
+  if (modality?.includes("NM")) {
+    const imageSubType = getImageTypeSubItemFromDataset(dataSet, 2);
+
+    if (imageSubType && isNMReconstructable(imageSubType)) {
+      if (dataSet.elements.x00540022) {
+        imageOrientationPatient = getNumberValues(
+          dataSet.elements.x00540022.items[0].dataSet,
+          "x00200037",
+          6
+        );
+      }
+    }
+  }
+
+  return imageOrientationPatient;
+}
+
+/**
+ * Extracts the position from NM multiframe dataset, if image type
+ * equal to RECON TOMO or RECON GATED TOMO
+ * @param {*} dataSet
+ * @returns
+ */
+function extractPositionFromNMMultiframeDataset(dataSet) {
+  let imagePositionPatient;
+  const modality = dataSet.string("x00080060");
+
+  if (modality?.includes("NM")) {
+    const imageSubType = getImageTypeSubItemFromDataset(dataSet, 2);
+
+    if (imageSubType && isNMReconstructable(imageSubType)) {
+      if (dataSet.elements.x00540022) {
+        imagePositionPatient = getNumberValues(
+          dataSet.elements.x00540022.items[0].dataSet,
+          "x00200032",
+          3
+        );
+      }
+    }
+  }
+
+  return imagePositionPatient;
+}
+
+function isMultiFrame(dataSet) {
+  const numberOfFrames =
+    dataSet.string("x00280008") || dataSet.uint16("x00280008");
+  return numberOfFrames !== undefined && Number(numberOfFrames) > 1;
+}
+
+/**
+ * Extract orientation information from a dataset. It tries to get the orientation
+ * from the Detector Information Sequence (for NM images) if image type equal
+ * to RECON TOMO or RECON GATED TOMO
+ * @param {*} dataSet
+ * @returns
+ */
+function extractOrientationFromDataset(dataSet) {
+  // let imageOrientationPatient;
+
+  // if (isMultiFrame(dataSet)) {
+  //   const perFrameDataSet = getPerFrameFunctionalGroupsDataSet(
+  //     dataSet,
+  //     frameIndex
+  //   );
+  //   imageOrientationPatient =
+  //     getOrientationFromPlaneOrientationSequence(perFrameDataSet);
+
+  //   if (!imageOrientationPatient) {
+  //     const sharedDataSet = getSharedFunctionalGroupsDataSet(dataSet);
+  //     imageOrientationPatient =
+  //       getOrientationFromPlaneOrientationSequence(sharedDataSet);
+  //   }
+  // }
+
+  // if (!imageOrientationPatient) {
+  //   imageOrientationPatient = getNumberValues(dataSet, "x00200037", 6);
+  // }
+  let imageOrientationPatient = getNumberValues(dataSet, "x00200037", 6)
+  // Trying to get the orientation from the Plane Orientation Sequence
+  if (!imageOrientationPatient && dataSet.elements.x00209116) {
+    imageOrientationPatient = getNumberValues(
+      dataSet.elements.x00209116.items[0].dataSet,
+      "x00200037",
+      6
+    );
+  }
+
+  // If orientation not valid to this point, trying to get the orientation
+  // from the Detector Information Sequence (for NM images) with image type
+  // equal to RECON TOMO or RECON GATED TOMO
+
+  if (!imageOrientationPatient) {
+    imageOrientationPatient =
+      extractOrientationFromNMMultiframeDataset(dataSet);
+  }
+
+  return imageOrientationPatient;
+}
+
+/**
+ * Extract position information from a dataset. It tries to get the position
+ * from the Detector Information Sequence (for NM images) if image type equal
+ * to RECON TOMO or RECON GATED TOMO
+ * @param {*} dataSet
+ * @returns
+ */
+function extractPositionFromDataset(dataSet) {
+  // let imagePositionPatient;
+
+  // if (isMultiFrame(dataSet)) {
+  //   const perFrameDataSet = getPerFrameFunctionalGroupsDataSet(
+  //     dataSet,
+  //     frameIndex
+  //   );
+  //   imagePositionPatient =
+  //     getPositionFromPlanePositionSequence(perFrameDataSet);
+
+  //   if (!imagePositionPatient) {
+  //     const sharedDataSet = getSharedFunctionalGroupsDataSet(dataSet);
+  //     imagePositionPatient =
+  //       getPositionFromPlanePositionSequence(sharedDataSet);
+  //   }
+  // }
+
+  // if (!imagePositionPatient) {
+  //   imagePositionPatient = getNumberValues(dataSet, "x00200032", 3);
+  // }
+  let imagePositionPatient = getNumberValues(dataSet, 'x00200032', 3);
+  // Trying to get the position from the Plane Position Sequence
+  if (!imagePositionPatient && dataSet.elements.x00209113) {
+    imagePositionPatient = getNumberValues(
+      dataSet.elements.x00209113.items[0].dataSet,
+      "x00200032",
+      3
+    );
+  }
+
+  // If position not valid to this point, trying to get the position
+  // from the Detector Information Sequence (for NM images)
+  if (!imagePositionPatient) {
+    imagePositionPatient = extractPositionFromNMMultiframeDataset(dataSet);
+  }
+
+  return imagePositionPatient;
+}
+
+/**
+ * Extract the pixelSpacing information. If exists, extracts this information
+ * from Pixel Measures Sequence
+ * @param {*} dataSet
+ * @returns
+ */
+function extractSpacingFromDataset(dataSet) {
+  // let pixelSpacing = getNumberValues(dataSet, 'x00280030', 2);
+
+  // // If pixelSpacing not valid to this point, trying to get the spacing
+  // // from the Pixel Measures Sequence
+  // if (!pixelSpacing && dataSet.elements.x00289110) {
+  //   pixelSpacing = getNumberValues(
+  //     dataSet.elements.x00289110.items[0].dataSet,
+  //     'x00280030',
+  //     2
+  //   );
+  // }
+
+  // return pixelSpacing;
+
+  let rowPixelSpacing = null;
+  let columnPixelSpacing = null;
+  // let pixelSpacing;
+
+  // if (isMultiFrame(dataSet)) {
+  //   const perFrameDataSet = getPerFrameFunctionalGroupsDataSet(
+  //     dataSet,
+  //     frameIndex
+  //   );
+  //   const sharedDataSet = getSharedFunctionalGroupsDataSet(dataSet);
+  //   pixelSpacing =
+  //     getPixelSpacingFromPixelMeasuresSequence(perFrameDataSet) ||
+  //     getPixelSpacingFromPixelMeasuresSequence(sharedDataSet);
+  // }
+
+  // if (!pixelSpacing) {
+  //   pixelSpacing =
+  //     getNumberValues(dataSet, "x00280030", 2) ||
+  //     getPixelSpacingFromPixelMeasuresSequence(dataSet);
+  // }
+  let pixelSpacing = getNumberValues(dataSet, 'x00280030', 2);
+  const imagePixelSpacing = getNumberValues(dataSet, "x00181164", 2);
+  const estimatedRadiographicMagnificationFactor = getNumberValues(
+    dataSet,
+    "x00181114",
+    2
+  );
+  if (pixelSpacing) {
+    rowPixelSpacing = pixelSpacing[0];
+    columnPixelSpacing = pixelSpacing[1];
+  } else if (imagePixelSpacing && estimatedRadiographicMagnificationFactor) {
+    rowPixelSpacing =
+      imagePixelSpacing[0] / estimatedRadiographicMagnificationFactor[0];
+    columnPixelSpacing =
+      imagePixelSpacing[1] / estimatedRadiographicMagnificationFactor[1];
+  } else if (imagePixelSpacing && !estimatedRadiographicMagnificationFactor) {
+    rowPixelSpacing = imagePixelSpacing[0];
+    columnPixelSpacing = imagePixelSpacing[1];
+  }
+  return rowPixelSpacing !== null
+    ? [rowPixelSpacing, columnPixelSpacing]
+    : undefined;
+}
+
+/**
+ * Extract the sliceThickness information. If exists, extracts this information
+ * from Pixel Measures Sequence
+ * @param {*} dataSet
+ * @returns
+ */
+function extractSliceThicknessFromDataset(dataSet) {
+  let sliceThickness;
+  if (dataSet.elements.x00180050) {
+      sliceThickness = dataSet.floatString('x00180050');
+  }
+  else if (dataSet.elements.x00289110 &&
+      dataSet.elements.x00289110.items.length &&
+      dataSet.elements.x00289110.items[0].dataSet.elements.x00180050) {
+      sliceThickness =
+          dataSet.elements.x00289110.items[0].dataSet.floatString('x00180050');
+  }
+
+  // if (sliceThickness === undefined && isMultiFrame(dataSet)) {
+  //   const perFrameDataSet = getPerFrameFunctionalGroupsDataSet(
+  //     dataSet,
+  //     frameIndex
+  //   );
+  //   const sharedDataSet = getSharedFunctionalGroupsDataSet(dataSet);
+  //   sliceThickness =
+  //     getSliceThicknessFromPixelMeasuresSequence(perFrameDataSet) ||
+  //     getSliceThicknessFromPixelMeasuresSequence(sharedDataSet);
+  // }
+
+  return sliceThickness;
+}
+
+export {
+  getImageTypeSubItemFromDataset,
+  extractOrientationFromDataset,
+  extractPositionFromDataset,
+  extractSpacingFromDataset,
+  extractSliceThicknessFromDataset,
+};
diff --git a/src/utils/getNumberValues.js b/src/utils/getNumberValues.js
new file mode 100644
index 00000000..7fcaad24
--- /dev/null
+++ b/src/utils/getNumberValues.js
@@ -0,0 +1,24 @@
+function getNumberValues(
+  dataSet,
+  tag,
+  minimumLength
+){
+  const values = [];
+  const valueAsString = dataSet.string(tag);
+
+  if (!valueAsString) {
+    return;
+  }
+  const split = valueAsString.split('\\');
+
+  if (minimumLength && split.length < minimumLength) {
+    return;
+  }
+  for (let i = 0; i < split.length; i++) {
+    values.push(parseFloat(split[i]));
+  }
+
+  return values;
+}
+
+export default getNumberValues;
diff --git a/src/utils/isNMReconstructable.js b/src/utils/isNMReconstructable.js
new file mode 100644
index 00000000..4a0909d2
--- /dev/null
+++ b/src/utils/isNMReconstructable.js
@@ -0,0 +1,3 @@
+export default function isNMReconstructable(imageSubType) {
+  return imageSubType === 'RECON TOMO' || imageSubType === 'RECON GATED TOMO';
+}
diff --git a/src/utils/metaDataProvider.js b/src/utils/metaDataProvider.js
index b840ddc0..d9c38b06 100644
--- a/src/utils/metaDataProvider.js
+++ b/src/utils/metaDataProvider.js
@@ -1,4 +1,11 @@
 import * as cornerstoneWADOImageLoader from 'cornerstone-wado-image-loader'
+import {
+  getImageTypeSubItemFromDataset,
+  extractOrientationFromDataset,
+  extractPositionFromDataset,
+  extractSpacingFromDataset,
+  extractSliceThicknessFromDataset,
+} from './extractPositioningFromDataset';
 function parseImageId(imageId) {
   // build a url by parsing out the url scheme and frame index from the imageId
   const firstColonIndex = imageId.indexOf(':');
@@ -141,6 +148,19 @@ function populatePaletteColorLut(dataSet, imagePixelModule) {
     imagePixelModule.bluePaletteColorLookupTableDescriptor
   );
 }
+
+function getSpacingBetweenSlices(dataSet) {
+  if (dataSet?.elements?.x00180088) {
+    return dataSet.floatString('x00180088');
+  }
+  const pixelMeasuresSequence = dataSet?.elements?.x00289110;
+  if (
+    pixelMeasuresSequence?.items?.length &&
+    pixelMeasuresSequence.items[0]?.dataSet?.elements?.x00180088
+  ) {
+    return pixelMeasuresSequence.items[0].dataSet.floatString('x00180088');
+  }
+}
 function metaDataProvider(type, imageId) {
   const parsedImageId = parseImageId(imageId);
   const dataSet = cornerstoneWADOImageLoader.wadouri.dataSetCacheManager.get(parsedImageId.url);
@@ -149,10 +169,47 @@ function metaDataProvider(type, imageId) {
     return;
   }
   if (type === 'imagePlaneModule') {
-    const imageOrientationPatient = getNumberValues(dataSet, 'x00200037', 6);
-    const imagePositionPatient = getNumberValues(dataSet, 'x00200032', 3);
-    const pixelSpacing = getNumberValues(dataSet, 'x00280030', 2);
+    // const imageOrientationPatient = getNumberValues(dataSet, 'x00200037', 6);
+    // const imagePositionPatient = getNumberValues(dataSet, 'x00200032', 3);
+    // const pixelSpacing = getNumberValues(dataSet, 'x00280030', 2);
     const imagePixelSpacing = getNumberValues(dataSet, 'x00181164', 2);
+    const frameIndex = parsedImageId.frame !== undefined ? parsedImageId.frame - 1 : undefined;
+    const imageOrientationPatient = extractOrientationFromDataset(dataSet, frameIndex);
+    let imagePositionPatient = extractPositionFromDataset(dataSet, frameIndex);
+    const pixelSpacing = extractSpacingFromDataset(dataSet, frameIndex);
+    const sliceThickness = extractSliceThicknessFromDataset(dataSet, frameIndex);
+
+    const modality = dataSet.string("x00080060");
+    if (modality && modality.includes('NM') && parsedImageId.frame !== undefined && parsedImageId.frame > 1) {
+      const spacingBetweenSlices = getSpacingBetweenSlices(dataSet);
+      const step = spacingBetweenSlices !== undefined ? spacingBetweenSlices : sliceThickness;
+      if (imageOrientationPatient && imagePositionPatient && step !== undefined && frameIndex !== undefined) {
+        const rowCosines = [
+          parseFloat(imageOrientationPatient[0]),
+          parseFloat(imageOrientationPatient[1]),
+          parseFloat(imageOrientationPatient[2]),
+        ];
+        const columnCosines = [
+          parseFloat(imageOrientationPatient[3]),
+          parseFloat(imageOrientationPatient[4]),
+          parseFloat(imageOrientationPatient[5]),
+        ];
+        const normal = [
+          rowCosines[1] * columnCosines[2] - rowCosines[2] * columnCosines[1],
+          rowCosines[2] * columnCosines[0] - rowCosines[0] * columnCosines[2],
+          rowCosines[0] * columnCosines[1] - rowCosines[1] * columnCosines[0],
+        ];
+
+        const offset = frameIndex * parseFloat(step);
+
+        imagePositionPatient = [
+          parseFloat(imagePositionPatient[0]) + normal[0] * offset,
+          parseFloat(imagePositionPatient[1]) + normal[1] * offset,
+          parseFloat(imagePositionPatient[2]) + normal[2] * offset,
+        ];
+      }
+    }
+
     const estimatedRadiographicMagnificationFactor = getNumberValues(dataSet, 'x00181114', 2);
     let columnPixelSpacing = null;
 
@@ -194,7 +251,7 @@ function metaDataProvider(type, imageId) {
       rowCosines,
       columnCosines,
       imagePositionPatient,
-      sliceThickness: dataSet.floatString('x00180050'),
+      sliceThickness,
       sliceLocation: dataSet.floatString('x00201041'),
       pixelSpacing,
       rowPixelSpacing,
@@ -224,6 +281,11 @@ function metaDataProvider(type, imageId) {
     }
     return imagePixelModule;
   }
+  // if (type === "multiframeModule") {
+  //   return {
+  //     NumberOfFrames: dataSet.uint16("x00280008") || dataSet.string("x00280008")
+  //   };
+  // }
   // if (type === 'imagePixelModule') {
   //   return {
   //     samplesPerPixel: dataSet.uint16('x00280002'),
@@ -249,4 +311,4 @@ function metaDataProvider(type, imageId) {
   //   }
   // }
 }
-export default metaDataProvider;
\ No newline at end of file
+export default metaDataProvider;
diff --git a/src/views/trials/trials-panel/reading/dicoms/components/Fusion/js/imagePixelSpacingMetaDataProvider.js b/src/views/trials/trials-panel/reading/dicoms/components/Fusion/js/imagePixelSpacingMetaDataProvider.js
index 6a2f283d..64a75482 100644
--- a/src/views/trials/trials-panel/reading/dicoms/components/Fusion/js/imagePixelSpacingMetaDataProvider.js
+++ b/src/views/trials/trials-panel/reading/dicoms/components/Fusion/js/imagePixelSpacingMetaDataProvider.js
@@ -1,10 +1,31 @@
-import cornerstoneDICOMImageLoader from '@cornerstonejs/dicom-image-loader'
+import cornerstoneDICOMImageLoader from "@cornerstonejs/dicom-image-loader";
+import {
+  getImageTypeSubItemFromDataset,
+  extractOrientationFromDataset,
+  extractPositionFromDataset,
+  extractSpacingFromDataset,
+  extractSliceThicknessFromDataset,
+} from "@/utils/extractPositioningFromDataset";
+import getNumberValues from "@/utils/getNumberValues";
+
+function getSpacingBetweenSlices(dataSet) {
+  if (dataSet?.elements?.x00180088) {
+    return dataSet.floatString("x00180088");
+  }
+  const pixelMeasuresSequence = dataSet?.elements?.x00289110;
+  if (
+    pixelMeasuresSequence?.items?.length &&
+    pixelMeasuresSequence.items[0]?.dataSet?.elements?.x00180088
+  ) {
+    return pixelMeasuresSequence.items[0].dataSet.floatString("x00180088");
+  }
+}
 function parseImageId(imageId) {
   // build a url by parsing out the url scheme and frame index from the imageId
-  const firstColonIndex = imageId.indexOf(':');
+  const firstColonIndex = imageId.indexOf(":");
 
   let url = imageId.substring(firstColonIndex + 1);
-  const frameIndex = url.indexOf('frame=');
+  const frameIndex = url.indexOf("frame=");
 
   let frame;
 
@@ -21,127 +42,112 @@ function parseImageId(imageId) {
     frame,
   };
 }
-function getNumberValues(dataSet, tag, minimumLength) {
-  const values = [];
-  const valueAsString = dataSet.string(tag);
 
-  if (!valueAsString) {
+function metaDataProvider(type, imageId) {
+  const parsedImageId = parseImageId(imageId);
+  const dataSet = cornerstoneDICOMImageLoader.wadouri.dataSetCacheManager.get(
+    parsedImageId.url
+  );
+  if (!dataSet) {
     return;
   }
-  const split = valueAsString.split('\\');
+  if (type === "imagePlaneModule") {
+    const frameIndex = parsedImageId.frame !== undefined ? parsedImageId.frame - 1 : undefined;
+    // const imageOrientationPatient = extractOrientationFromDataset(dataSet, frameIndex);
+    // let imagePositionPatient = extractPositionFromDataset(dataSet, frameIndex);
+    // const pixelSpacing = extractSpacingFromDataset(dataSet, frameIndex);
+    // const sliceThickness = extractSliceThicknessFromDataset(dataSet, frameIndex);
+    const imageOrientationPatient = extractOrientationFromDataset(dataSet);
+    let imagePositionPatient = extractPositionFromDataset(dataSet);
+    const pixelSpacing = extractSpacingFromDataset(dataSet);
+    const sliceThickness = extractSliceThicknessFromDataset(dataSet);
+ 
+    const modality = dataSet.string("x00080060");
+    if (
+      modality &&
+      modality.includes("NM") &&
+      parsedImageId.frame !== undefined &&
+      parsedImageId.frame > 1
+    ) {
+      // 坐标堆叠 (位置相同) ：NM 多帧 DICOM 的空间位置 ( imagePositionPatient ) 通常只存在于 Detector Information Sequence 序列的第一个 Item 中。原来的代码在提取位置时，所有帧都被赋予了第一帧的位置。因为所有帧都挤在一个坐标上，3D 引擎无法根据厚度和法向量空间展开它们，导致间距 (Spacing) 为 0
+      // 当识别到 NM 多帧图像且属于多帧切片时，通过 RowCosines 与 ColumnCosines 的叉乘计算出切片的 法向量(Normal) ，并结合 帧索引 (frameIndex) 以及 Spacing Between Slices (0018,0088)（层间距） 或者 Slice Thickness (0018,0050)（层厚） ，自动推算补全后续每一帧的 imagePositionPatient 真实三维坐标
+      // 
+      if (
+        imageOrientationPatient &&
+        imagePositionPatient &&
+        sliceThickness !== undefined
+      ) {
+        const spacingBetweenSlices = getSpacingBetweenSlices(dataSet);
+        const step =
+          spacingBetweenSlices !== undefined ? spacingBetweenSlices : sliceThickness;
+        const rowCosines = [
+          parseFloat(imageOrientationPatient[0]),
+          parseFloat(imageOrientationPatient[1]),
+          parseFloat(imageOrientationPatient[2]),
+        ];
+        const columnCosines = [
+          parseFloat(imageOrientationPatient[3]),
+          parseFloat(imageOrientationPatient[4]),
+          parseFloat(imageOrientationPatient[5]),
+        ];
+        const normal = [
+          rowCosines[1] * columnCosines[2] - rowCosines[2] * columnCosines[1],
+          rowCosines[2] * columnCosines[0] - rowCosines[0] * columnCosines[2],
+          rowCosines[0] * columnCosines[1] - rowCosines[1] * columnCosines[0],
+        ];
 
-  if (minimumLength && split.length < minimumLength) {
-    return;
-  }
-  for (let i = 0; i < split.length; i++) {
-    values.push(parseFloat(split[i]));
-  }
+        const offset = frameIndex * parseFloat(step);
 
-  return values;
-}
-function getImageTypeSubItemFromDataset(dataSet, index) {
-  const imageType = dataSet.string('x00080008');
-  if (imageType) {
-      const subTypes = imageType.split('\\');
-      if (subTypes.length > index) {
-          return subTypes[index];
+        imagePositionPatient = [
+          parseFloat(imagePositionPatient[0]) + normal[0] * offset,
+          parseFloat(imagePositionPatient[1]) + normal[1] * offset,
+          parseFloat(imagePositionPatient[2]) + normal[2] * offset,
+        ];
       }
-  }
-  return undefined;
-}
-function isNMReconstructable(imageSubType) {
-  return imageSubType === 'RECON TOMO' || imageSubType === 'RECON GATED TOMO';
-}
-function extractOrientationFromNMMultiframeDataset(dataSet) {
-  let imageOrientationPatient;
-  const modality = dataSet.string('x00080060');
-  if (modality?.includes('NM')) {
-      const imageSubType = getImageTypeSubItemFromDataset(dataSet, 2);
-      if (imageSubType && isNMReconstructable(imageSubType)) {
-          if (dataSet.elements.x00540022) {
-              imageOrientationPatient = getNumberValues(dataSet.elements.x00540022.items[0].dataSet, 'x00200037', 6);
-          }
-      }
-  }
-  return imageOrientationPatient;
-}
-function extractOrientationFromDataset(dataSet) {
-  let imageOrientationPatient = getNumberValues(dataSet, 'x00200037', 6);
-  if (!imageOrientationPatient && dataSet.elements.x00209116) {
-      imageOrientationPatient = getNumberValues(dataSet.elements.x00209116.items[0].dataSet, 'x00200037', 6);
-  }
-  if (!imageOrientationPatient) {
-      imageOrientationPatient =
-          extractOrientationFromNMMultiframeDataset(dataSet);
-  }
-  return imageOrientationPatient;
-}
-function extractPositionFromNMMultiframeDataset(dataSet) {
-  let imagePositionPatient;
-  const modality = dataSet.string('x00080060');
-  if (modality?.includes('NM')) {
-      const imageSubType = getImageTypeSubItemFromDataset(dataSet, 2);
-      if (imageSubType && isNMReconstructable(imageSubType)) {
-          if (dataSet.elements.x00540022) {
-              imagePositionPatient = getNumberValues(dataSet.elements.x00540022.items[0].dataSet, 'x00200032', 3);
-          }
-      }
-  }
-  return imagePositionPatient;
-}
-function extractPositionFromDataset(dataSet) {
-  let imagePositionPatient = getNumberValues(dataSet, 'x00200032', 3);
-  if (!imagePositionPatient && dataSet.elements.x00209113) {
-      imagePositionPatient = getNumberValues(dataSet.elements.x00209113.items[0].dataSet, 'x00200032', 3);
-  }
-  if (!imagePositionPatient) {
-      imagePositionPatient = extractPositionFromNMMultiframeDataset(dataSet);
-  }
-  return imagePositionPatient;
-}
-function extractSliceThicknessFromDataset(dataSet) {
-  let sliceThickness;
-  if (dataSet.elements.x00180050) {
-      sliceThickness = dataSet.floatString('x00180050');
-  }
-  else if (dataSet.elements.x00289110 &&
-      dataSet.elements.x00289110.items.length &&
-      dataSet.elements.x00289110.items[0].dataSet.elements.x00180050) {
-      sliceThickness =
-          dataSet.elements.x00289110.items[0].dataSet.floatString('x00180050');
-  }
-  return sliceThickness;
-}
-function extractSpacingFromDataset(dataSet) {
-  let rowPixelSpacing = null
-  let columnPixelSpacing = null
-  let pixelSpacing = getNumberValues(dataSet, 'x00280030', 2);
-  const imagePixelSpacing = getNumberValues(dataSet, 'x00181164', 2);
-  const estimatedRadiographicMagnificationFactor = getNumberValues(dataSet, 'x00181114', 2);
-  if (pixelSpacing) {
-      rowPixelSpacing = pixelSpacing[0]
-      columnPixelSpacing = pixelSpacing[1]
+    }
+
+    // const imageOrientationPatient = getNumberValues(dataSet, 'x00200037', 6);
+    // const imagePositionPatient = getNumberValues(dataSet, 'x00200032', 3);
+    // const pixelSpacing = extractSpacingFromDataset(dataSet);
+    const imagePixelSpacing = getNumberValues(dataSet, "x00181164", 2);
+
+    // let rowCosines = null;
+
+    // let columnCosines = null;
+
+    // if (imageOrientationPatient) {
+    //   rowCosines = [
+    //     parseFloat(imageOrientationPatient[0]),
+    //     parseFloat(imageOrientationPatient[1]),
+    //     parseFloat(imageOrientationPatient[2]),
+    //   ];
+    //   columnCosines = [
+    //     parseFloat(imageOrientationPatient[3]),
+    //     parseFloat(imageOrientationPatient[4]),
+    //     parseFloat(imageOrientationPatient[5]),
+    //   ];
+    // }
+    const estimatedRadiographicMagnificationFactor = getNumberValues(
+      dataSet,
+      "x00181114",
+      2
+    );
+    let columnPixelSpacing = null;
+
+    let rowPixelSpacing = null;
+
+    if (pixelSpacing) {
+      rowPixelSpacing = pixelSpacing[0];
+      columnPixelSpacing = pixelSpacing[1];
     } else if (imagePixelSpacing && estimatedRadiographicMagnificationFactor) {
-      rowPixelSpacing = imagePixelSpacing[0] / estimatedRadiographicMagnificationFactor[0];
-      columnPixelSpacing = imagePixelSpacing[1] / estimatedRadiographicMagnificationFactor[1];
+      rowPixelSpacing =
+        imagePixelSpacing[0] / estimatedRadiographicMagnificationFactor[0];
+      columnPixelSpacing =
+        imagePixelSpacing[1] / estimatedRadiographicMagnificationFactor[1];
     } else if (imagePixelSpacing && !estimatedRadiographicMagnificationFactor) {
       rowPixelSpacing = imagePixelSpacing[0];
       columnPixelSpacing = imagePixelSpacing[1];
     }
-  return rowPixelSpacing !== null ? [rowPixelSpacing, columnPixelSpacing] : undefined
-}
-function metaDataProvider(type, imageId) {
-  const parsedImageId = parseImageId(imageId);
-  const dataSet = cornerstoneDICOMImageLoader.wadouri.dataSetCacheManager.get(parsedImageId.url)
-  
-  
-  if (!dataSet) {
-    return;
-  }
-  if (type === 'imagePlaneModule') {
-    const imageOrientationPatient = getNumberValues(dataSet, 'x00200037', 6);
-    const imagePositionPatient = getNumberValues(dataSet, 'x00200032', 3);
-    const pixelSpacing = extractSpacingFromDataset(dataSet);
 
     let rowCosines = null;
 
@@ -160,34 +166,35 @@ function metaDataProvider(type, imageId) {
       ];
     }
     return {
-      frameOfReferenceUID: dataSet.string('x00200052'),
-      rows: dataSet.uint16('x00280010'),
-      columns: dataSet.uint16('x00280011'),
+      frameOfReferenceUID: dataSet.string("x00200052"),
+      rows: dataSet.uint16("x00280010"),
+      columns: dataSet.uint16("x00280011"),
       imageOrientationPatient,
       rowCosines,
       columnCosines,
       imagePositionPatient,
-      sliceThickness: dataSet.floatString('x00180050'),
-      sliceLocation: dataSet.floatString('x00201041'),
-      pixelSpacing: pixelSpacing,
-      rowPixelSpacing: pixelSpacing ? pixelSpacing[0] : null,
-      columnPixelSpacing: pixelSpacing ? pixelSpacing[1] : null,
+      sliceThickness,
+      sliceLocation: dataSet.floatString("x00201041"),
+      pixelSpacing,
+      rowPixelSpacing,
+      columnPixelSpacing,
     };
   }
-  if (type === 'nmMultiframeGeometryModule') {
-    const modality = dataSet.string('x00080060');
-      const imageSubType = getImageTypeSubItemFromDataset(dataSet, 2);
-      return {
-          modality,
-          imageType: dataSet.string('x00080008'),
-          imageSubType,
-          imageOrientationPatient: extractOrientationFromDataset(dataSet),
-          imagePositionPatient: extractPositionFromDataset(dataSet),
-          sliceThickness: extractSliceThicknessFromDataset(dataSet),
-          pixelSpacing: extractSpacingFromDataset(dataSet),
-          numberOfFrames: dataSet.uint16('x00280008'),
-          isNMReconstructable: isNMReconstructable(imageSubType) && modality.includes('NM'),
-      };
+  if (type === "nmMultiframeGeometryModule") {
+    const modality = dataSet.string("x00080060");
+    const imageSubType = getImageTypeSubItemFromDataset(dataSet, 2);
+    return {
+      modality,
+      imageType: dataSet.string("x00080008"),
+      imageSubType,
+      imageOrientationPatient: extractOrientationFromDataset(dataSet),
+      imagePositionPatient: extractPositionFromDataset(dataSet),
+      sliceThickness: extractSliceThicknessFromDataset(dataSet),
+      pixelSpacing: extractSpacingFromDataset(dataSet),
+      numberOfFrames: dataSet.uint16("x00280008"),
+      isNMReconstructable:
+        isNMReconstructable(imageSubType) && modality.includes("NM"),
+    };
   }
 }
-export default metaDataProvider;
\ No newline at end of file
+export default metaDataProvider;
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue
index a2262c30..c9ce9b8b 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue
@@ -17,7 +17,7 @@
         {{ `${series.TaskInfo.SubjectCode} ${series.TaskInfo.TaskBlindName} ` }}
       </h2>
       <div v-if="!isMip && !isFusion">Series: #{{ series.SeriesNumber }}</div>
-      <div v-if="series.Stack && !isMip">Image: #{{ `${series.SliceIndex + 1}/${series.Stack.length}` }}</div>
+      <div v-if="series.Stack && !isMip">Image: #{{ `${series.SliceIndex + 1}/${imageInfo.total || series.Stack.length}` }}</div>
       <div v-if="!isMip && !isFusion">{{ series.Modality }}</div>
       <div v-if="isFusion">{{ ctSeries.Modality }} / {{ series.Modality }}</div>
       <div v-if="isMip">MIP</div>
@@ -103,7 +103,7 @@ import {
   setMipTransferFunctionForVolumeActor,
   setPetTransferFunctionForVolumeActor
 } from './helpers/index.js'
-const { BlendModes, OrientationAxis } = Enums;
+const { BlendModes, OrientationAxis } = Enums; 
 const { getColormap } = csUtils.colormap;
 import { vec3, mat4 } from 'gl-matrix'
 export default {
@@ -149,7 +149,8 @@ export default {
         size: null,
         location: null,
         sliceThickness: null,
-        wwwc: null
+        wwwc: null,
+        total: null
       },
       digitPlaces: 2,
       orientationMarkers: [],
@@ -224,7 +225,9 @@ export default {
       if (this.series) {
         this.series.SliceIndex = detail.imageIndex
       }
-      this.sliderInfo.height = detail.imageIndex * 100 / detail.numberOfSlices
+      this.imageInfo.total = detail.numberOfSlices
+      const maxIndex = detail.numberOfSlices > 1 ? detail.numberOfSlices - 1 : 1
+      this.sliderInfo.height = detail.imageIndex * 100 / maxIndex
       const renderingEngine = getRenderingEngine(this.renderingEngineId)
       const viewport = renderingEngine.getViewport(this.viewportId)
       const zoom = viewport.getZoom()
@@ -414,9 +417,6 @@ export default {
       const renderingEngine = getRenderingEngine(this.renderingEngineId)
       const voiRange = { lower: 0, upper: v }
       this.currentVoiUpper = v
-      if (this.isFusion) {
-        console.log('voiChange', v)
-      }
       
       const viewport = renderingEngine.getViewport(this.viewportId)
       if (!viewport) return
@@ -476,12 +476,21 @@ export default {
       const renderingEngine = getRenderingEngine(this.renderingEngineId)
       const viewport = renderingEngine.getViewport(this.viewportId)
       if (!viewport) return
-      let volumeId = this.isFusion ? this.ptVolumeId : this.volumeId
 
-      viewport.setProperties(
-        { colormap: { opacity: Number(opacity) } },
-        volumeId
-      )
+      if (this.isFusion) {
+        const ctVolumeId = this.ctSeries?.SeriesInstanceUid
+        const ptVolumeId = this.ptVolumeId
+        const topVolumeId = this.fusionCtOnTop ? ctVolumeId : ptVolumeId
+        const bottomVolumeId = this.fusionCtOnTop ? ptVolumeId : ctVolumeId
+        const topOpacity = Number(opacity)
+        const bottomOpacity = 1 - topOpacity
+        if (bottomVolumeId) {
+          viewport.setProperties({ colormap: { opacity: bottomOpacity } }, bottomVolumeId)
+        }
+        if (topVolumeId) {
+          viewport.setProperties({ colormap: { opacity: topOpacity } }, topVolumeId)
+        }
+      }
       viewport.render()
     },
     applyFusionOpacity() {
@@ -512,11 +521,14 @@ export default {
     },
     async createImageIdsAndCacheMetaData(obj) {
       this.loading = true
-      await createImageIdsAndCacheMetaData({
-        modality: obj.Modality,
-        imageIds: obj.ImageIds
-      })
-      this.loading = false
+      try {
+        return await createImageIdsAndCacheMetaData({
+          modality: obj.Modality,
+          imageIds: obj.ImageIds
+        })
+      } finally {
+        this.loading = false
+      }
     },
     getFusionVolumes() {
       const ctVolumeId = this.ctSeries?.SeriesInstanceUid
@@ -531,8 +543,8 @@ export default {
           setCtTransferFunctionForVolumeActor({ ...r, volumeId: ctVolumeId })
           if (this.fusionCtOnTop) {
             this.topFusionVolumeActor = r.volumeActor
-            this.applyFusionOpacity()
           }
+          this.applyFusionOpacity()
           console.log("融合ct渲染成功")
         }
       }
@@ -543,8 +555,8 @@ export default {
           setPetColorMapTransferFunctionForVolumeActor({ ...r, volumeId: ptFusionVolumeId })
           if (!this.fusionCtOnTop) {
             this.topFusionVolumeActor = r.volumeActor
-            this.applyFusionOpacity()
           }
+          this.applyFusionOpacity()
           console.log("融合pet渲染成功")
         }
       }
@@ -709,8 +721,10 @@ export default {
     clickSlider(e) {
       const height = e.offsetY * 100 / this.$refs['sliderBox'].clientHeight
       this.sliderInfo.height = height
-      let sliceIdx = Math.trunc(this.series.Stack.length * height / 100)
-      sliceIdx = sliceIdx >= this.series.Stack.length ? this.series.Stack.length - 1 : sliceIdx < 0 ? 0 : sliceIdx
+      const totalSlices = this.imageInfo.total || this.series.Stack?.length || 1
+      const maxIndex = totalSlices > 1 ? totalSlices - 1 : 0
+      let sliceIdx = Math.round(maxIndex * height / 100)
+      sliceIdx = sliceIdx > maxIndex ? maxIndex : sliceIdx < 0 ? 0 : sliceIdx
       const renderingEngine = getRenderingEngine(this.renderingEngineId)
       const viewport = renderingEngine.getViewport(
         this.viewportId
@@ -725,7 +739,7 @@ export default {
     },
     sliderMousedown(e) {
       const boxHeight = this.$refs['sliderBox'].clientHeight
-      this.sliderInfo.oldB = parseInt(e.srcElement.style.top) * boxHeight / 100
+      this.sliderInfo.oldB = this.sliderInfo.height * boxHeight / 100
       this.sliderInfo.oldM = e.clientY
       this.sliderInfo.isMove = true
       e.stopImmediatePropagation()
@@ -739,8 +753,10 @@ export default {
       if (delta < 0) return
       if (delta > boxHeight) return
       const height = delta * 100 / boxHeight
-      let sliceIdx = Math.trunc(this.series.Stack.length * height / 100)
-      sliceIdx = sliceIdx >= this.series.Stack.length ? this.series.Stack.length - 1 : sliceIdx < 0 ? 0 : sliceIdx
+      const totalSlices = this.imageInfo.total || this.series.Stack?.length || 1
+      const maxIndex = totalSlices > 1 ? totalSlices - 1 : 0
+      let sliceIdx = Math.round(maxIndex * height / 100)
+      sliceIdx = sliceIdx > maxIndex ? maxIndex : sliceIdx < 0 ? 0 : sliceIdx
       this.sliderInfo.height = height
       const renderingEngine = getRenderingEngine(this.renderingEngineId)
       const viewport = renderingEngine.getViewport(
@@ -891,7 +907,9 @@ export default {
 
     .opacity-slider {
       -webkit-appearance: slider-vertical;
-      writing-mode: bt-lr;
+      appearance: slider-vertical;
+      writing-mode: vertical-lr;
+      direction: rtl;
       width: 10px;
       height: 150px;
       padding: 0;
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
index eff2e12c..1c6bc950 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
@@ -3696,8 +3696,8 @@ export default {
         if (cache.getVolume(volumeId)) {
           volume = cache.getVolume(volumeId)
         } else {
-          await this.$refs[`${this.viewportKey}-0`][0].createImageIdsAndCacheMetaData(serie)
-          let imageIds = this.sortImageIdsByImagePositionPatient(serie.ImageIds)
+          let imageIds = await this.$refs[`${this.viewportKey}-0`][0].createImageIdsAndCacheMetaData(serie)
+          // imageIds = this.sortImageIdsByImagePositionPatient(imageIds)
           volume = await volumeLoader.createAndCacheVolume(volumeId, { imageIds: imageIds })
           volume.load()
         }