diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue
index e5fda1b2..00e12ca8 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/PetCtViewport.vue
@@ -244,7 +244,7 @@ export default {
         this.imageInfo.size = `${imagePlaneModule.columns}*${imagePlaneModule.rows}`
         this.imageInfo.location = imagePlaneModule.sliceLocation
         this.getOrientationMarker()
-        this.$emit('renderAnnotations', this.series)
+        // this.$emit('renderAnnotations', this.series)
         let properties = viewport.getProperties()
         if (this.isFusion) {
           properties = viewport.getProperties(this.ptVolumeId)
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
index 26d1983c..a94222a9 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
@@ -709,7 +709,8 @@ export default {
       studyList: [],
       volumeData: {},
       fusionSerieId: {},
-      loadingText: null
+      loadingText: null,
+      resetAnnotation: false , // 是否初始化标记 （融合时使用）
     }
   },
   computed: {
@@ -1472,6 +1473,7 @@ export default {
     async customAnnotationRemovedListener(e) {
       const { annotation } = e.detail
       try{
+        if ( this.resetAnnotation && this.isFusion ) return false
         if (!annotation) return false
         if (this.readingTaskState === 2) throw 'annotation Not allowed to operate'
         if (annotation.visitTaskId === this.taskInfo.VisitTaskId && annotation.seriesId) {
@@ -2734,6 +2736,10 @@ export default {
         let { ct, pt } = data
         this.loading = true
         this.loadingText = this.$t('trials:lugano:message:loadVolumes')
+        this.resetAnnotation = true
+        // console.log(cornerstoneTools.annotation.state.getAllAnnotations(),'cornerstoneTools.annotation.state')
+        // cornerstoneTools.annotation.state.removeAllAnnotations()
+        this.renderedTaskIds = []
         if ( this.verifyFusionData(ct, pt) ) {
           this.loading = false
           this.loadingText = null
@@ -2741,6 +2747,7 @@ export default {
           this.$refs[`viewport-1`][0].setSeriesInfo(pt)
           this.$refs[`viewport-2`][0].setSeriesInfo(pt)
           this.$refs[`viewport-3`][0].setSeriesInfo(pt)
+          this.resetAnnotation = false
           return true
         }
         if (!this.fusionSerieId.ct || this.fusionSerieId.ct !== ct.SeriesInstanceUid ) {
@@ -2780,6 +2787,7 @@ export default {
         this.$refs[`viewport-fusion-1`][0].setSeriesInfo(ptData, { colorMap: true})
         this.$refs[`viewport-fusion-2`][0].setSeriesInfo(fusionData, { isFusion: true, colorMap: true })
         this.$refs[`viewport-fusion-3`][0].setSeriesInfo(ptData, { isMip: true, colorMap: true })
+        this.resetAnnotation = false
         this.$nextTick(() => {
           this.$refs[`colorMap`].init()
         })
diff --git a/src/views/trials/trials-panel/visit/crc-upload/components/uploadDicomFiles2.vue b/src/views/trials/trials-panel/visit/crc-upload/components/uploadDicomFiles2.vue
index 6c773385..376b2fcd 100644
--- a/src/views/trials/trials-panel/visit/crc-upload/components/uploadDicomFiles2.vue
+++ b/src/views/trials/trials-panel/visit/crc-upload/components/uploadDicomFiles2.vue
@@ -1459,6 +1459,11 @@ export default {
                                 ) {
                                   dicomInfo.uploadFileSize = dicomInfo.fileSize
                                 }
+                                if (
+                                  Math.abs(dicomInfo.uploadFileSize - dicomInfo.fileSize) < 5000
+                                ) {
+                                  dicomInfo.uploadFileSize = dicomInfo.fileSize
+                                }
                               }
                             )
                             if (!res || !res.url) {