diff --git a/src/icons/svg/thresholecircle.svg b/src/icons/svg/thresholecircle.svg
new file mode 100644
index 00000000..545fb0f5
--- /dev/null
+++ b/src/icons/svg/thresholecircle.svg
@@ -0,0 +1 @@
+<svg width="24px" height="24px" viewBox="0 0 24 24" class="h-6 w-6"><g id="tool-seg-threshold" stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"><rect id="Rectangle" x="0" y="0" width="24" height="24"></rect><g id="Group" transform="translate(2.4184, 14.3673)" stroke="currentColor" stroke-width="1.5"><line x1="16.5816327" y1="2.13265306" x2="19.0816327" y2="2.13265306" id="Line-2" stroke-linecap="round"></line><line x1="0.0816326531" y1="2.13265306" x2="12.0816327" y2="2.13265306" id="Line-2" stroke-linecap="round"></line><circle id="Oval" cx="14.2244898" cy="2.09183673" r="2.09183673"></circle></g><g id="Group" transform="translate(11.7092, 7.4592) scale(-1, 1) translate(-11.7092, -7.4592)translate(1.9184, 5.3673)" stroke="currentColor" stroke-width="1.5"><line x1="16" y1="2.13265306" x2="19.0816327" y2="2.13265306" id="Line-2" stroke-linecap="round"></line><line x1="0.0816326531" y1="2.13265306" x2="11" y2="2.13265306" id="Line-2" stroke-linecap="round"></line><circle id="Oval" cx="13.2244898" cy="2.09183673" r="2.09183673"></circle></g></g></svg>
\ No newline at end of file
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
index c09e6c45..4f5bb967 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
@@ -273,11 +273,7 @@
             </div>
             <!-- 伪彩 -->
             <template v-if="readingTool === 2">
-              <colorMap 
-                v-show="isFusion" 
-                ref="colorMap"
-                :modality="fusionOverlayModality" 
-                @setColorMap="setColorMap" 
+              <colorMap v-show="isFusion" ref="colorMap" :modality="fusionOverlayModality" @setColorMap="setColorMap"
                 @voiChange="voiChange" />
             </template>
           </div>
@@ -308,7 +304,7 @@
                 :class="['viewports-box', isFusion || isMPR ? 'viewports-box-down' : '', fullScreenIndex !== null ? 'viewports-box-full-screen' : '']"
                 :style="gridStyle">
                 <div v-for="(v, index) in cellsMax" v-show="index < cells.length" :key="`viewport-${index}`"
-                  :class="['grid-cell', isMPR && index === 2 ? 'grid-cell-3' : '', index === activeViewportIndex ? 'cell_active' : '', index === fullScreenIndex ? 'cell-full-screen' : '']"
+                  :class="['grid-cell', index === activeViewportIndex ? 'cell_active' : '', index === fullScreenIndex ? 'cell-full-screen' : '']"
                   @dblclick="toggleFullScreen($event, index)" @click="activeViewport(index)">
                   <VolumeViewport :ref="`viewport-${index}`" :data-viewport-uid="`viewport-${index}`"
                     :rendering-engine-id="renderingEngineId" :viewport-id="`viewport-${index}`" :viewport-index="index"
@@ -325,7 +321,7 @@
                 :style="gridStyleMPR">
                 <div v-for="(v, index) in 3" :key="`viewport-MPR-${index}`" v-show="index < cells.length"
                   :style="cellStyle"
-                  :class="['grid-cell', isMPR && index === 0 ? 'grid-cell-3' : '', index === activeViewportIndex ? 'cell_active' : '', index === fullScreenIndex ? 'cell-full-screen' : '']"
+                  :class="['grid-cell', index === 0 ? 'grid-cell-3' : '', index === activeViewportIndex ? 'cell_active' : '', index === fullScreenIndex ? 'cell-full-screen' : '']"
                   @dblclick="toggleFullScreen($event, index)" @click="activeViewport(index)">
                   <MPRViewport :ref="`viewport-MPR-${index}`" :data-viewport-uid="`viewport-MPR-${index}`"
                     :rendering-engine-id="renderingEngineId" :viewport-id="`viewport-MPR-${index}`"
@@ -369,10 +365,11 @@
               </el-tab-pane>
               <el-tab-pane :label="$t('trials:reading:dicom3D:tabs:segment')" name="segment">
                 <Segmentations ref="Segmentations" :visitInfo="taskInfo" :isMPR="isMPR"
-                  :volumeToolGroupId="volumeToolGroupId" :viewportKey="viewportKey"
-                  :rendering-engine-id="renderingEngineId" :activeViewportIndex="activeViewportIndex"
-                  :activeTool.sync="activeTool" :actionConfiguration="actionConfiguration"
-                  @setToolsPassive="setToolsPassive" @resetQuestion="resetQuestion" />
+                  :volumeToolGroupId="volumeToolGroupId" :viewportKey="viewportKey" :global-loading.sync="loading"
+                  :loadingText.sync="loadingText" :rendering-engine-id="renderingEngineId"
+                  :activeViewportIndex="activeViewportIndex" :activeTool.sync="activeTool"
+                  :actionConfiguration="actionConfiguration" @setToolsPassive="setToolsPassive"
+                  @resetQuestion="resetQuestion" />
               </el-tab-pane>
             </el-tabs>
             <template v-else>
@@ -1379,6 +1376,20 @@ export default {
 
             }
           )
+          toolGroup.addToolInstance(
+            'ThresholdCircle',
+            BrushTool.toolName,
+            {
+              activeStrategy: 'THRESHOLD_INSIDE_CIRCLE',
+            }
+          )
+          toolGroup.addToolInstance(
+            'ThresholdSphere',
+            BrushTool.toolName,
+            {
+              activeStrategy: 'THRESHOLD_INSIDE_SPHERE',
+            }
+          )
           toolGroup.addTool(LabelMapEditWithContourTool.toolName);
           toolGroup.addTool(SegmentBidirectionalTool.toolName);
         }
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue
index 7379dc43..22598def 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue
@@ -12,6 +12,12 @@
                         @click.prevent="setToolActive('LabelMapEditWithContour')">
                         <svg-icon icon-class="contour" class="svg-icon" />
                     </div>
+                    <div :title="$t('trials:Segmentations:tools:thresholecircle')"
+                        :class="['tool-item', ThresholdTools.includes(activeTool) && segmentList.length > 0 ? 'tool-item-active' : '']"
+                        :style="{ cursor: segmentList.length <= 0 || (curSegment && curSegment.lock) ? 'not-allowed' : 'pointer' }"
+                        @click.prevent="initThreshold">
+                        <svg-icon icon-class="thresholecircle" class="svg-icon" />
+                    </div>
                     <div :title="$t('trials:Segmentations:tools:circularbrush')"
                         :class="['tool-item', activeTool === 'CircularBrush' && segmentList.length > 0 ? 'tool-item-active' : '']"
                         :style="{ cursor: segmentList.length <= 0 || (curSegment && curSegment.lock) ? 'not-allowed' : 'pointer' }"
@@ -28,11 +34,41 @@
                     </div> -->
                 </div>
                 <div class="ConfigBox">
-                    <div class="EraserConfig" v-if="activeTool === 'CircularEraser' || activeTool === 'CircularBrush'">
+                    <div class="EraserConfig"
+                        v-if="activeTool === 'CircularEraser' || activeTool === 'CircularBrush' || ThresholdTools.includes(activeTool)">
                         <span>{{ $t('trials:reading:Segmentations:title:EraserConfig') }}</span>
                         <el-slider v-model="brushSize" show-input :step="1" :max="100" input-size="mini"
                             :show-input-controls="false" />
                     </div>
+                    <div class="EraserConfig" v-if="ThresholdTools.includes(activeTool)">
+                        <span>{{ $t('trials:reading:Segmentations:title:thresholdType') }}</span>
+                        <el-radio-group v-model="thresholdType" @input="(key) => setToolActive(key)">
+                            <el-radio-button :label="tool" v-for="tool of ThresholdTools" :key="tool" size="mini">
+                                {{ $t(`trials:reading:Segmentations:radioButton:${tool}`) }}
+                            </el-radio-button>
+                        </el-radio-group>
+                    </div>
+                    <div class="EraserConfig" v-if="ThresholdTools.includes(activeTool)">
+                        <span>{{ $t('trials:reading:Segmentations:title:isDynamic') }}</span>
+                        <el-radio-group v-model="brushThreshold.isDynamic">
+                            <el-radio-button :label="true" size="mini">
+                                {{ $t('trials:reading:Segmentations:radioButton:Dynamic') }}
+                            </el-radio-button>
+                            <el-radio-button :label="false" size="mini">
+                                {{ $t('trials:reading:Segmentations:radioButton:Rang') }}
+                            </el-radio-button>
+                        </el-radio-group>
+                    </div>
+                    <div class="EraserConfig" v-if="ThresholdTools.includes(activeTool) && !brushThreshold.isDynamic">
+                        <span>{{ $t('trials:reading:Segmentations:title:range') }}</span>
+                        <div style="display: flex;align-items: center;">
+                            <el-input-number v-model="brushThreshold.range[0]" :controls="false" :step="1"
+                                :max="brushThreshold.range[1]" size="small" />
+                            <span style="margin: 0 10px;">--</span>
+                            <el-input-number v-model="brushThreshold.range[1]" :controls="false" :step="1"
+                                :min="brushThreshold.range[0]" size="small" />
+                        </div>
+                    </div>
                 </div>
             </el-collapse-item>
             <el-collapse-item name="Segment">
@@ -84,7 +120,7 @@
                         </el-switch>
                         <span style="margin-left: 5px;">{{
                             $t('trials:reading:Segmentations:title:InactiveSegmentationsShow')
-                            }}</span>
+                        }}</span>
                     </div>
                     <!-- <div class="SegmentConfig" v-if="SegmentConfig.InactiveSegmentations.show">
                         <span>{{ $t('trials:reading:Segmentations:title:Opacity') }}</span>
@@ -112,7 +148,7 @@
                             <i slot="reference" class="el-icon-more" style="cursor: pointer;color:#fff" />
                         </el-popover>
                         <el-select v-model="segmentationId" placeholder="" @change="selectSegmentGroup">
-                            <el-option v-for="item in segmentList" :key="item.segmentationId" :label="item.name"
+                            <el-option v-for="item in segmentList" :key="`${item.segmentationId}`" :label="item.name"
                                 :value="item.segmentationId">
                             </el-option>
                         </el-select>
@@ -155,7 +191,7 @@
                                         <div v-for="k in statsKey" :key="k" class="statsBox">
                                             <span>{{ k }}</span>
                                             <span v-if="item.stats[k]">{{ Number(item.stats[k].value).toFixed(2)
-                                                }}<i>{{ item.stats[k].unit }}</i></span>
+                                            }}<i>{{ item.stats[k].unit }}</i></span>
                                         </div>
                                     </template>
                                     <div class="serialNum" slot="reference">{{ item.segmentIndex }}</div>
@@ -262,6 +298,14 @@ export default {
             type: String,
             required: true
         },
+        loadingText: {
+            type: String,
+            default: ''
+        },
+        globalLoading: {
+            type: Boolean,
+            default: false
+        }
     },
     data() {
         return {
@@ -269,6 +313,13 @@ export default {
             series: {},
             activeNames: ['tools', 'Segment'],
             brushSize: 10,
+            brushThreshold: {
+                dynamicRadius: 0,
+                isDynamic: false,
+                range: [200, 1000]
+            },
+            ThresholdTools: ['ThresholdCircle', 'ThresholdSphere'],
+            thresholdType: null,
             showSegmentConfig: false,
             SegmentConfig: {
                 renderOutline: true,
@@ -344,12 +395,25 @@ export default {
         },
         brushSize: {
             handler() {
-                this.setBrushSize()
+                this.setBrushSize(this.activeTool)
+            },
+            deep: true
+        },
+        brushThreshold: {
+            handler() {
+                this.setBrushThreshold()
             },
             deep: true
         }
     },
     methods: {
+        initThreshold() {
+            if (!this.ThresholdTools.includes(this.activeTool)) {
+                this.setToolActive(this.ThresholdTools[0])
+                this.thresholdType = this.ThresholdTools[0]
+            }
+
+        },
         createSegmentConfiguration(segmentIndex, segmentationId, otherSegments) {
             const containedSegmentIndices = otherSegments
                 ? { has: (segmentIndex) => otherSegments.indexOf(segmentIndex) !== -1 }
@@ -469,8 +533,12 @@ export default {
                 toolGroup.setToolActive(toolName, {
                     bindings: [{ mouseButton: MouseBindings.Primary }]
                 })
-                this.setBrushSize()
                 this.$emit('update:activeTool', toolName)
+                this.setBrushSize(toolName)
+                if (this.ThresholdTools.includes(toolName)) {
+                    this.setBrushThreshold()
+                }
+
             }
         },
         changeShowSegmentConfig() {
@@ -504,12 +572,12 @@ export default {
                 } else {
                     const points = an.data.handles.points;
                     const worldPoint = points[0]; // 取一个点
-                    let imageData = cache.getVolume(this.series.SeriesInstanceUid).imageData
+                    let volume = cache.getVolume(this.series.SeriesInstanceUid)
+                    let { imageData, numFrames } = volume
                     const ijk = imageData.worldToIndex(worldPoint);
                     const sliceIndex = Math.abs(Math.round(ijk[2]));
-                    let imageIds = viewport.getImageIds(this.series.SeriesInstanceUid)
                     // console.log(sliceIndex, 'sliceIndex')
-                    csUtils.jumpToSlice(viewport.element, { imageIndex: imageIds.length - sliceIndex - 1 });
+                    csUtils.jumpToSlice(viewport.element, { imageIndex: numFrames - sliceIndex - 1 });
                 }
 
             }
@@ -1052,9 +1120,30 @@ export default {
                 }
             )
         },
-        setBrushSize() {
+        setBrushSize(toolName = null) {
             const toolGroupId = this.isMPR ? this.volumeToolGroupId : `${this.viewportKey}-${this.activeViewportIndex}`
             CStUtils.segmentation.setBrushSizeForToolGroup(toolGroupId, this.brushSize);
+            if (toolName === 'ThresholdSphere') {
+                this.setDynamicRadius()
+            }
+        },
+        setDynamicRadius() {
+            let volume = cache.getVolume(this.series.SeriesInstanceUid);
+            let { spacing, numFrames } = volume
+            let constant = numFrames * spacing[2] / 100
+            this.brushThreshold.dynamicRadius = Math.ceil(this.brushSize * constant)
+            // console.log(this.brushThreshold.dynamicRadius)
+        },
+        setBrushThreshold() {
+            const toolGroupId = this.isMPR ? this.volumeToolGroupId : `${this.viewportKey}-${this.activeViewportIndex}`
+            let brushThreshold = {
+                isDynamic: this.brushThreshold.isDynamic,
+                dynamicRadius: this.brushThreshold.dynamicRadius,
+            }
+            if (!this.brushThreshold.isDynamic) {
+                brushThreshold.range = this.brushThreshold.range
+            }
+            CStUtils.segmentation.setBrushThresholdForToolGroup(toolGroupId, brushThreshold);
         },
         async createSegmentation(segmentationId) {
             const toolGroupId = this.isMPR ? this.volumeToolGroupId : `${this.viewportKey}-${this.activeViewportIndex}`
@@ -1070,18 +1159,21 @@ export default {
                     }
                 )
             }
-            segmentation.addSegmentations([
-                {
-                    segmentationId,
-                    representation: {
-                        type: cornerstoneTools.Enums.SegmentationRepresentations
-                            .Labelmap,
-                        data: {
-                            volumeId: segmentationId
+            if (!segmentation.state.getSegmentation(segmentationId)) {
+                segmentation.addSegmentations([
+                    {
+                        segmentationId,
+                        representation: {
+                            type: cornerstoneTools.Enums.SegmentationRepresentations
+                                .Labelmap,
+                            data: {
+                                volumeId: segmentationId
+                            }
                         }
                     }
-                }
-            ]);
+                ]);
+            }
+
         },
         segmentationModifiedCallback(evt) {
             const { detail } = evt;
@@ -1097,6 +1189,7 @@ export default {
             this.drawing = true
         },
         async calculateStatistics(indices, segmentationId, mode) {
+            if (!segmentation.state.getSegmentation(segmentationId)) return false
             const stats = await segmentationUtils.getStatistics({
                 segmentationId,
                 segmentIndices: indices,
@@ -1151,16 +1244,19 @@ export default {
                 if (!this.isDel) {
                     this.calculateStatistics([this.segmentIndex], this.segmentationId, 'individual');
                     let segmentGroup = this.segmentList.find(item => item.segmentationId === this.segmentationId)
-                    let segment = segmentGroup.segments.find(item => item.segmentIndex === this.segmentIndex)
-                    this.getBidirectional([segment])
+                    let segment = segmentGroup ? segmentGroup.segments.find(item => item.segmentIndex === this.segmentIndex) : null
+                    if (segment) this.getBidirectional([segment])
                 } else {
                     let segmentGroup = this.segmentList.find(item => item.segmentationId === this.segmentationId)
-                    let segmentIndexs = []
-                    segmentGroup.segments.forEach(item => {
-                        segmentIndexs.push(item.segmentIndex)
-                    })
-                    this.getBidirectional(segmentGroup.segments)
-                    this.calculateStatistics(segmentIndexs, this.segmentationId, 'individual');
+                    if (segmentGroup && segmentGroup.segments && segmentGroup.segments.length > 0) {
+                        let segmentIndexs = []
+                        segmentGroup.segments.forEach(item => {
+                            segmentIndexs.push(item.segmentIndex)
+                        })
+                        this.getBidirectional(segmentGroup.segments)
+                        this.calculateStatistics(segmentIndexs, this.segmentationId, 'individual');
+                    }
+
                 }
                 this.isDel = false
 
@@ -1243,6 +1339,8 @@ export default {
                     let confirm = await this.$confirm(this.$t("segment:confirm:questionNeedChange"))
                     if (!confirm) return false
                 }
+                this.$emit("update:globalLoading", true)
+                this.$emit("update:loadingText", this.$t("segment:loadingText:saveSegmentation"))
                 for (let i = 0; i < this.segmentList.length; i++) {
                     let segmentGroup = this.segmentList[i]
                     // 将所有分割进行锁定
@@ -1266,6 +1364,7 @@ export default {
                     })
                 }
                 if (bindingList.length > 0) this.saveSegmentBindingAndAnswer(bindingList)
+                this.$emit("update:globalLoading", false)
             } catch (err) {
                 this.loading = false
                 console.log(err)
@@ -1310,6 +1409,7 @@ export default {
                 let res = await getSegmentationList(data);
                 this.loading = false;
                 if (res.IsSuccess) {
+                    this.segmentList = []
                     let list = res.Result.CurrentPageData;
                     for (let i = 0; i < list.length; i++) {
                         let item = list[i]
@@ -1356,7 +1456,6 @@ export default {
                         })
                     }
                 }
-                // console.log(segmentation.state.getSegmentations(), 'segmentation.state.getSegmentations()')
             } catch (err) {
                 this.loading = false
                 console.log(err)
@@ -1701,6 +1800,19 @@ export default {
     }
 }
 
+.EraserConfig {
+    margin: 5px 0;
+
+    ::v-deep .el-input-number {
+        width: 50px;
+    }
+
+    ::v-deep .el-input-number.is-without-controls .el-input__inner {
+        padding: 0 5px;
+        width: 50px;
+    }
+}
+
 .SegmentConfig {
     padding: 5px;
 }
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/VolumeViewport.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/VolumeViewport.vue
index e5865567..11ad513f 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/VolumeViewport.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/VolumeViewport.vue
@@ -270,7 +270,8 @@ export default {
             const viewport = renderingEngine.getViewport(this.viewportId)
             const zoom = viewport.getZoom()
             this.imageInfo.zoom = zoom.toFixed(4)
-            let imageId = viewport.getCurrentImageId()
+            let imageIds = viewport.getImageIds(this.volumeId)
+            let imageId = imageIds[0]
             if (imageId) {
                 const imagePlaneModule = metaData.get('imagePlaneModule', imageId)
                 this.imageInfo.imageOrientationPatient = imagePlaneModule.imageOrientationPatient