diff --git a/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionFormItem.vue b/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionFormItem.vue
index 8889bae9..8a05e509 100644
--- a/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionFormItem.vue
+++ b/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionFormItem.vue
@@ -69,6 +69,10 @@
         :rules="[
           { required: (question.IsRequired === 0 || (question.IsRequired ===1 && question.RelevanceId && (question.RelevanceValueList.includes(isNaN(parseFloat(questionForm[question.RelevanceId])) ? questionForm[question.RelevanceId] : questionForm[question.RelevanceId].toString())))) && question.Type!=='group' && question.Type!=='summary',
             message: $t('common:ruleMessage:specify'), trigger: ['blur', 'change']},
+            {
+              validator: question.Type === 'number' && !question.TypeValue ? validatorNumberInput :(rule,value,callback )=>{callback()},
+              trigger: ['blur', 'change']
+            }
         ]"
         :class="[question.Type==='group'?'mb':question.Type==='upload'?'uploadWrapper':'']"
       >
@@ -228,9 +232,10 @@
           />
         </el-select>
         <el-input
-          type="number"
+          type="text"
           v-if="question.Type === 'number' && !question.TypeValue && question.DataSource !== 1"
           @change="(val) => { formItemNumberChange(val, question) }"
+          @input="numberInput(question.Id)"
           @blur="handleBlur(questionForm[question.Id], questionForm, question.Id)"
           v-model="questionForm[question.Id]"
           :disabled="readingTaskState === 2"
@@ -240,7 +245,8 @@
           <template slot="append" v-else-if="question.ValueType === 2">%</template>
         </el-input>
         <el-input
-          type="number"
+          type="text"
+          @input="numberInput(question.Id)"
           v-if="question.Type === 'number' && !question.TypeValue && question.DataSource === 1"
           @blur="handleBlur(questionForm[question.Id], questionForm, question.Id)"
           :disabled="question.DataSource === 1 || readingTaskState === 2"
@@ -502,6 +508,21 @@ export default {
     }
   },
   methods: {
+    numberInput(id) {
+      this.questionForm[id] = this.questionForm[id].toUpperCase();
+    },
+    validatorNumberInput(rule, value, callback) {
+      let reg = new RegExp(/^(?:-?(?:(?:0|[1-9]\d*)(?:\.\d+)?|\.\d+)|NE)$/, 'g')
+       if (value === '') {
+          callback(new Error(this.$t('common:ruleMessage:specify')));
+        } else {
+          if (!reg.test(value)) {
+            callback(new Error(this.$t('trials:reading:ruleMessage:validatorNumberInput')));
+          }else{
+            callback();
+          }
+        }
+    },
     limitInput(value, a, b) {
       if (value.indexOf('.') > -1) {
         if (value.split('.')[1].length >= this.digitPlaces) {
@@ -510,7 +531,10 @@ export default {
       }
     },
     handleBlur(value, a, b) {
-      this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      let reg = new RegExp(/[a-zA-Z]/, 'ig')
+      if(!reg.test(value)) {
+        this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      }
     },
     deleteTableCol(row, index) {
       this.$confirm(this.$t('trials:uploadNonDicoms:message:msg1')).then(() => {
diff --git a/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionTableFormItem.vue b/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionTableFormItem.vue
index 251666fd..42acda72 100644
--- a/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionTableFormItem.vue
+++ b/src/views/trials/trials-panel/reading/dicoms/customize/CustomizeQuestionTableFormItem.vue
@@ -7,6 +7,10 @@
         :rules="[
           { required: (question.IsRequired === 0 || (question.IsRequired ===1 && question.RelevanceId && !!~question.RelevanceValueList.indexOf(questionForm[question.RelevanceId]))) && question.Type!=='group' && question.Type!=='summary',
             message:  $t('common:ruleMessage:select'), trigger: ['blur', 'change']},
+          {
+            validator: question.Type === 'number' && !question.TypeValue ? validatorNumberInput :(rule,value,callback )=>{callback()},
+            trigger: ['blur', 'change']
+          }
         ]"
         :class="[question.Type==='group'?'mb':question.Type==='upload'?'uploadWrapper':'']"
       >
@@ -144,19 +148,21 @@
         <!-- 数值 -->
         <!-- :precision="2" :step="0.1" :max="10" -->
         <el-input
-          type="number"
+          type="text"
           v-if="question.Type === 'number' && question.DataSource !== 1"
           :disabled="question.TableQuestionType === 2 || (question.IsCopy && type === 'edit' && !IsBaseline && questionForm.IsCurrentTaskAdd === 'False')"
           @change="((val)=>{formItemNumberChange(val, question)})"
+          @input="numberInput(question.Id)"
           @blur="handleBlur(questionForm[question.Id], questionForm, question.Id)"
           v-model="questionForm[question.Id]"
         >
           <template slot="append" v-if="question.Unit !== 0">{{question.Unit !== 4 ? $fd('ValueUnit', question.Unit) : question.CustomUnit}}</template>
         </el-input>
         <el-input
-          type="number"
+          type="text"
           v-if="question.Type === 'number' && question.DataSource === 1"
           :disabled="question.DataSource === 1"
+          @input="numberInput(question.Id, true )"
           @blur="handleCalculationBlur(calculationValue)"
           v-model="calculationValue"
         >
@@ -342,6 +348,25 @@ export default {
     // }
   },
   methods: {
+    numberInput(id,notId = false) {
+      if(notId ) {
+        this.calculationValue = this.calculationValue.toUpperCase();
+      }else {
+        this.questionForm[id] = this.questionForm[id].toUpperCase();
+      }
+    },
+    validatorNumberInput(rule, value, callback) {
+      let reg = new RegExp(/^(?:-?(?:(?:0|[1-9]\d*)(?:\.\d+)?|\.\d+)|NE)$/, 'g')
+       if (value === '') {
+          callback(new Error(this.$t('common:ruleMessage:specify')));
+        } else {
+          if (!reg.test(value)) {
+            callback(new Error(this.$t('trials:reading:ruleMessage:validatorNumberInput')));
+          }else{
+            callback();
+          }
+        }
+    },
     save() {
     },
     openAddTableCol(row) {
@@ -382,7 +407,11 @@ export default {
       }
     },
     handleBlur(value, a, b) {
-      this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      let reg = new RegExp(/[a-zA-Z]/, 'ig')
+      if(!reg.test(value)) {
+        this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      }
+      // this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
     },
     handleCalculationBlur(v) {
       this.calculationValue = parseFloat(v).toFixed(this.digitPlaces)
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionFormItem.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionFormItem.vue
index df3e2b38..7441a60c 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionFormItem.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionFormItem.vue
@@ -121,6 +121,10 @@
         :rules="[
           { required: (question.IsRequired === 0 || (question.IsRequired ===1 && question.RelevanceId && (question.RelevanceValueList.includes(isNaN(parseFloat(questionForm[question.RelevanceId])) ? questionForm[question.RelevanceId] : questionForm[question.RelevanceId].toString())))) && question.Type!=='group' && question.Type!=='summary',
             message: $t('common:ruleMessage:specify'), trigger: ['blur', 'change']},
+          {
+            validator: question.Type === 'number' && !question.TypeValue ? validatorNumberInput :(rule,value,callback )=>{callback()},
+            trigger: ['blur', 'change']
+          }
         ]"
         :class="[question.Type==='group'?'mb':question.Type==='upload'?'uploadWrapper':'']"
       >
@@ -354,9 +358,10 @@
         </template>
         <template v-else-if="question.Type === 'number'">
           <el-input
-            type="number"
+            type="text"
             v-if="question.Type === 'number' && !question.TypeValue && question.DataSource !== 1"
             @change="(val) => { formItemNumberChange(val, question) }"
+            @input="numberInput(question.Id)"
             @blur="handleBlur(questionForm[question.Id], questionForm, question.Id)"
             v-model="questionForm[question.Id]"
             :disabled="readingTaskState === 2"
@@ -367,7 +372,8 @@
 
           </el-input>
           <el-input
-            type="number"
+            type="text"
+            @input="numberInput(question.Id)"
             v-if="question.Type === 'number' && !question.TypeValue && question.DataSource === 1"
             @blur="handleBlur(questionForm[question.Id], questionForm, question.Id)"
             :disabled="question.DataSource === 1 || readingTaskState === 2"
@@ -648,6 +654,21 @@ export default {
     }
   },
   methods: {
+    numberInput(id) {
+      this.questionForm[id] = this.questionForm[id].toUpperCase();
+    },
+    validatorNumberInput(rule, value, callback) {
+      let reg = new RegExp(/^(?:-?(?:(?:0|[1-9]\d*)(?:\.\d+)?|\.\d+)|NE)$/, 'g')
+       if (value === '') {
+          callback(new Error(this.$t('common:ruleMessage:specify')));
+        } else {
+          if (!reg.test(value)) {
+            callback(new Error(this.$t('trials:reading:ruleMessage:validatorNumberInput')));
+          }else{
+            callback();
+          }
+        }
+    },
     limitInput(value, a, b) {
       if (value.indexOf('.') > -1) {
         if (value.split('.')[1].length >= this.digitPlaces) {
@@ -656,7 +677,11 @@ export default {
       }
     },
     handleBlur(value, a, b) {
-      this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      let reg = new RegExp(/[a-zA-Z]/, 'ig')
+      if(!reg.test(value)) {
+        this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      }
+      // this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
     },
     handleMarkedQsBlur(value, a, b, question) {
       this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionTableFormItem.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionTableFormItem.vue
index 12add325..0be8dc0a 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionTableFormItem.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/customize/QuestionTableFormItem.vue
@@ -7,6 +7,10 @@
       :rules="[
         { required: (question.IsRequired === 0 || (question.IsRequired ===1 && question.RelevanceId && !!~question.RelevanceValueList.indexOf(questionForm[question.RelevanceId]))) && question.Type!=='group' && question.Type!=='summary',
           message:  $t('common:ruleMessage:select'), trigger: ['blur', 'change']},
+        {
+          validator: question.Type === 'number' && !question.TypeValue ? validatorNumberInput :(rule,value,callback )=>{callback()},
+          trigger: ['blur', 'change']
+        }
       ]"
       :class="[question.Type==='group'?'mb':question.Type==='upload'?'uploadWrapper':'']"
     >
@@ -217,19 +221,21 @@
       </template>
       <template v-else-if="question.Type === 'number'">
         <el-input
-          type="number"
+          type="text"
           v-if="question.Type === 'number' && question.DataSource !== 1"
           :disabled="question.TableQuestionType === 2 || (question.IsCopy && type === 'edit' && !isBaseline && questionForm.IsCurrentTaskAdd === 'False')"
           @change="((val)=>{formItemNumberChange(val, question)})"
+          @input="numberInput(question.Id)"
           @blur="handleBlur(questionForm[question.Id], questionForm, question.Id)"
           v-model="questionForm[question.Id]"
         >
           <template slot="append" v-if="question.Unit !== 0">{{question.Unit !== 4 ? $fd('ValueUnit', question.Unit) : question.CustomUnit}}</template>
         </el-input>
         <el-input
-          type="number"
+          type="text"
           v-if="question.Type === 'number' && question.DataSource === 1"
           :disabled="question.DataSource === 1"
+          @input="numberInput(question.Id, true )"
           @blur="handleCalculationBlur(calculationValue)"
           v-model="calculationValue"
         >
@@ -420,6 +426,25 @@ export default {
     if (this.type === 'edit') return
   },
   methods: {
+    numberInput(id,notId = false) {
+      if(notId ) {
+        this.calculationValue = this.calculationValue.toUpperCase();
+      }else {
+        this.questionForm[id] = this.questionForm[id].toUpperCase();
+      }
+    },
+    validatorNumberInput(rule, value, callback) {
+      let reg = new RegExp(/^(?:-?(?:(?:0|[1-9]\d*)(?:\.\d+)?|\.\d+)|NE)$/, 'g')
+       if (value === '') {
+          callback(new Error(this.$t('common:ruleMessage:specify')));
+        } else {
+          if (!reg.test(value)) {
+            callback(new Error(this.$t('trials:reading:ruleMessage:validatorNumberInput')));
+          }else{
+            callback();
+          }
+        }
+    },
     save() {
     },
     openAddTableCol(row) {
@@ -449,7 +474,11 @@ export default {
       }
     },
     handleBlur(value, a, b) {
-      this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      let reg = new RegExp(/[a-zA-Z]/, 'ig')
+      if(!reg.test(value)) {
+        this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
+      }
+      // this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))
     },
     handleMarkedQsBlur(value, a, b, question) {
       this.$set(a, b, parseFloat(value).toFixed(this.digitPlaces))