diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
index 71a98c29..96a8f1e8 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/ReadPage.vue
@@ -3723,7 +3723,7 @@ export default {
       })
       this.setToolsPassive()
     },
-    async activeSeries(obj) {
+    async activeSeries(obj, isSave = false) {
       if (this.readingTool === 3) {
         let res = await this.changeScreenSave()
         if (!res) return false
@@ -3735,6 +3735,7 @@ export default {
           if (!confirm) return false
           this.$refs[`ecrf_${this.taskInfo.VisitTaskId}`][0].removeAllNoSaveAnnotation()
         } else {
+          if (isSave) return false
           const confirm = await this.$confirm(this.$t('trials:reading:confirm:changeStack'))
           if (!confirm) return false
         }
@@ -4022,7 +4023,7 @@ export default {
           }
           let res = await this.openMPRViewport(series)
           if (!res) {
-            this.$refs[series.TaskInfo.VisitTaskId][0].setSeriesActive(series.StudyIndex, series.SeriesIndex)
+            this.$refs[series.TaskInfo.VisitTaskId][0].setSeriesActive(series.StudyIndex, series.SeriesIndex, true)
             setTimeout(async () => {
               const divForDownloadViewport = document.querySelector(
                 `div[data-viewport-uid="${this.viewportKey}-${this.activeViewportIndex}"]`
@@ -4534,7 +4535,7 @@ export default {
       return new Promise(async (resolve, reject) => {
         this.setToolsPassive()
         if (this.isMPR) {
-          this.activeSeries(this.$refs[`viewport-MPR-0`][0].series)
+          this.activeSeries(this.$refs[`viewport-MPR-0`][0].series, true)
           resolve(false)
           if (!data) return resolve(false)
           let viewportSeries = this.$refs[`viewport-MPR-0`][0].series
diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/StudyList.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/StudyList.vue
index bcd6b3ff..9b176542 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/StudyList.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/StudyList.vue
@@ -14,7 +14,7 @@
     <div class="ps">
       <el-collapse v-model="activeNames">
 
-        <el-collapse-item v-for="(study, index) in studyList" :key="`${study.StudyId}`"  :name="`${study.StudyId}`">
+        <el-collapse-item v-for="(study, index) in studyList" :key="`${study.StudyId}`" :name="`${study.StudyId}`">
           <template slot="title">
             <div v-if="!study.IsCriticalSequence" class="dicom-desc">
               <div style="text-overflow: ellipsis;overflow: hidden;">
@@ -24,7 +24,8 @@
               </div>
               <div>
                 <span class="study-meta-line" :title="study.Modalities">
-                  <span v-if="taskInfo && taskInfo.IsReadingTaskViewInOrder !== 0" class="study-code" :title="study.StudyCode">{{ study.StudyCode }}</span>
+                  <span v-if="taskInfo && taskInfo.IsReadingTaskViewInOrder !== 0" class="study-code"
+                    :title="study.StudyCode">{{ study.StudyCode }}</span>
                   <span class="study-modality">{{ `${study.Modalities}(${study.SeriesCount})` }}</span>
                   <span class="patient-info" v-if="['PT、CT', 'CT、PT', 'PET-CT'].includes(study.Modalities)">
                     <el-popover placement="right-start" trigger="hover" popper-class="patient-info-popper">
@@ -81,8 +82,7 @@
                     style="position: absolute;right: 0;top: 0;">
                     <el-popover placement="right" trigger="hover" popper-class="instance_frame_wrapper">
                       <div class="frame_list">
-                        <div v-for="(instance, idx) in series.InstanceInfoList" :key="instance.Id"
-                          class="frame_content"
+                        <div v-for="(instance, idx) in series.InstanceInfoList" :key="instance.Id" class="frame_content"
                           :class="{ 'frame_content_active': activeInstanceId === instance.Id }"
                           :style="{ 'margin-bottom': idx < series.InstanceInfoList.length - 1 ? '5px' : '0px' }"
                           @click.stop="showMultiFrames(index, series, i, instance)">
@@ -130,7 +130,7 @@
             </div>
           </div>
         </el-collapse-item>
-  
+
 
       </el-collapse>
     </div>
@@ -205,18 +205,19 @@ export default {
       this.activeStudyIndex = studyIndex
       this.activeSeriesIndex = seriesIndex
       this.activeInstanceId = null
-    }, 
+    },
     activeStudy(id) {
       console.log('activeStudy')
       if (this.activeNames.indexOf(id) > -1) return
       this.activeNames.push(id)
     },
-    setSeriesActive(studyIndex, seriesIndex) {
+    setSeriesActive(studyIndex, seriesIndex, isSave = false) {
       this.activeStudyIndex = studyIndex
       this.activeSeriesIndex = seriesIndex
       const studyId = this.studyList[studyIndex].StudyId
       if (!studyId) return
       this.activeStudy(studyId)
+      if (isSave) return false
       DicomEvent.$emit('activeSeries', this.studyList[studyIndex].SeriesList[this.activeSeriesIndex])
     },
     showMultiFrames(studyIndex, series, seriesIndex, instance) {
@@ -482,25 +483,29 @@ export default {
 
 <style lang="scss">
 .study-wrapper {
-  .instance_frame_wrapper{
+  .instance_frame_wrapper {
     min-width: 120px;
     background-color: #2c2c2c;
     border: 1px solid #2c2c2c;
     padding: 5px;
   }
-  .frame_list{
+
+  .frame_list {
     max-height: 500px;
     overflow-y: auto;
   }
+
   .instance_frame_wrapper ::-webkit-scrollbar {
     width: 7px;
     height: 7px;
   }
-  .instance_frame_wrapper  ::-webkit-scrollbar-thumb {
+
+  .instance_frame_wrapper ::-webkit-scrollbar-thumb {
     border-radius: 10px;
     background: #d0d0d0;
   }
-  .frame_content{
+
+  .frame_content {
     height: 50px;
     padding: 5px;
     display: flex;
@@ -509,6 +514,7 @@ export default {
     font-size: 12px;
     border: 1px solid #404040;
   }
+
   .frame_content:hover {
     /* font-weight: bold; */
     /* box-shadow: 0 2px 12px 0 rgba(0, 0, 0, 0.1); */
@@ -517,10 +523,10 @@ export default {
     border-color: #213a54 !important;
     background-color: #213a54;
   }
+
   .frame_content_active {
     border-color: #213a54 !important;
     background-color: #213a54;
   }
 }
-
 </style>