diff --git a/src/components/Dicom/DicomViewer.vue b/src/components/Dicom/DicomViewer.vue
index 583b303a..82482896 100644
--- a/src/components/Dicom/DicomViewer.vue
+++ b/src/components/Dicom/DicomViewer.vue
@@ -327,14 +327,22 @@
               <el-input v-model.number="formData.RadionuclideHalfLife" :placeholder="$t('trials:halfLife:eg')"
                 style="width: 100%" :disabled="!isEdit"></el-input>
             </el-form-item>
-            <!-- 注射时间（s） Unix 秒 或 相对秒-->
+            <!-- 注射时间 HHMMSS-->
             <el-form-item :label="$t('trials:ptData:label:injectTime')" prop="RadiopharmaceuticalStartTime">
-              <el-input v-model.number="formData.RadiopharmaceuticalStartTime" :placeholder="$t('trials:injectTime:eg')"
+              <el-input 
+                v-model.trim="formData.RadiopharmaceuticalStartTime" 
+                :placeholder="$t('trials:injectTime:eg')"
+                @blur="handleTimeBlur('RadiopharmaceuticalStartTime')"
+                maxlength="6"
                 style="width: 100%" @input="computeTimeRelation" :disabled="!isEdit"></el-input>
             </el-form-item>
-            <!-- 成像时间（s） Unix 秒 或 相对秒-->
+            <!-- 成像时间 HHMMSS-->
             <el-form-item :label="$t('trials:ptData:label:acquisitionTime')" prop="AcquisitionTime">
-              <el-input v-model.number="formData.AcquisitionTime" :placeholder="$t('trials:injectTime:eg')"
+              <el-input 
+                v-model.trim="formData.AcquisitionTime" 
+                @blur="handleTimeBlur('AcquisitionTime')"
+                maxlength="6"
+                :placeholder="$t('trials:injectTime:eg')"
                 style="width: 100%" @input="computeTimeRelation" :disabled="!isEdit"></el-input>
             </el-form-item>
             <!-- 时间一致性检查 -->
@@ -447,8 +455,8 @@ export default {
         PatientWeight: null,
         RadionuclideTotalDose: null,
         RadionuclideHalfLife: null,
-        RadiopharmaceuticalStartTime: null,
-        AcquisitionTime: null,
+        RadiopharmaceuticalStartTime: '',
+        AcquisitionTime: '',
         TimeCheck: ''
       },
       rules: {
@@ -469,11 +477,11 @@ export default {
         ],
         RadiopharmaceuticalStartTime: [
           { required: true, message: this.$t('common:ruleMessage:specify'), trigger: 'blur' },
-          { type: 'number', message: this.$t('trials:ptData:ruleMessage:number2'), trigger: 'blur' }//请输入数字
+          { validator: this.validateDicomTime, trigger: 'blur' }
         ],
         AcquisitionTime: [
           { required: true, message: this.$t('common:ruleMessage:specify'), trigger: 'blur' },
-          { type: 'number', message: this.$t('trials:ptData:ruleMessage:number2'), trigger: 'blur' },//请输入数字
+          { validator: this.validateDicomTime, trigger: 'blur' },
           // 自定义校验：确保成像时间不早于注射时间
           { validator: this.validateTime, trigger: 'blur' }
         ]
@@ -1017,12 +1025,68 @@ export default {
     // 时间一致性校验
     validateTime(rule, value, callback) {
       const { RadiopharmaceuticalStartTime } = this.formData
-      if (value && RadiopharmaceuticalStartTime !== null && value < RadiopharmaceuticalStartTime) {
+      const acquireSeconds = this.timeToSeconds(value)
+      const startSeconds = this.timeToSeconds(RadiopharmaceuticalStartTime)
+      if (acquireSeconds !== null && startSeconds !== null && acquireSeconds < startSeconds) {
         callback(new Error(this.$t('trials:ptData:ruleMessage:number3')))//成像时间不能早于注射时间
       } else {
         callback()
       }
     },
+    validateDicomTime(rule, value, callback) {
+      if (value === undefined || value === null || value === '') {
+        callback()
+        return
+      }
+      const raw = String(value).trim()
+      if (!/^\d{1,6}$/.test(raw)) {
+        callback(new Error(this.$t('trials:ptData:ruleMessage:number2')))
+        return
+      }
+      const normalized = this.normalizeClinicalTime(raw)
+      if (!this.isValidDicomTime(normalized)) {
+        callback(new Error(this.$t('trials:ptData:ruleMessage:number4')))//请输入有效时间（HHMMSS）
+        return
+      }
+      callback()
+    },
+    normalizeClinicalTime(value) {
+      if (value === undefined || value === null || value === '') return ''
+      const digits = String(value).trim().replace(/[^\d]/g, '')
+      if (!digits) return ''
+      return digits.slice(0, 6).padStart(6, '0')
+    },
+    isValidDicomTime(value) {
+      if (!/^\d{6}$/.test(String(value || ''))) return false
+      const normalized = String(value)
+      const hh = Number(normalized.slice(0, 2))
+      const mm = Number(normalized.slice(2, 4))
+      const ss = Number(normalized.slice(4, 6))
+      return hh >= 0 && hh <= 23 && mm >= 0 && mm <= 59 && ss >= 0 && ss <= 59
+    },
+    timeToSeconds(value) {
+      const normalized = this.normalizeClinicalTime(value)
+      if (!this.isValidDicomTime(normalized)) return null
+      const hh = Number(normalized.slice(0, 2))
+      const mm = Number(normalized.slice(2, 4))
+      const ss = Number(normalized.slice(4, 6))
+      return hh * 3600 + mm * 60 + ss
+    },
+    handleTimeBlur(field) {
+      const value = this.formData[field]
+      if (value === undefined || value === null || value === '') return
+      this.formData[field] = this.normalizeClinicalTime(value)
+      this.computeTimeRelation()
+    },
+    normalizeTimeFields() {
+      this.formData.RadiopharmaceuticalStartTime = this.normalizeClinicalTime(
+        this.formData.RadiopharmaceuticalStartTime
+      )
+      this.formData.AcquisitionTime = this.normalizeClinicalTime(
+        this.formData.AcquisitionTime
+      )
+      this.computeTimeRelation()
+    },
     computeTimeRelation() {
       const startTime = this.formData.RadiopharmaceuticalStartTime
       const acquireTime = this.formData.AcquisitionTime
@@ -1032,7 +1096,14 @@ export default {
         return
       }
 
-      if (startTime <= acquireTime) {
+      const startSeconds = this.timeToSeconds(startTime)
+      const acquireSeconds = this.timeToSeconds(acquireTime)
+      if (startSeconds === null || acquireSeconds === null) {
+        this.formData.TimeCheck = ''
+        return
+      }
+
+      if (startSeconds <= acquireSeconds) {
         this.formData.TimeCheck = this.$t('trials:ptData:timeCheck:val1') //注射时间 ≤ 成像时间
       } else {
         this.formData.TimeCheck = this.$t('trials:ptData:timeCheck:val2') //注射时间 > 成像时间
@@ -1049,8 +1120,8 @@ export default {
           PatientWeight: parseFloat(res.Result.PatientWeight) || null,
           RadionuclideTotalDose: parseFloat(res.Result.RadionuclideTotalDose) || null,
           RadionuclideHalfLife: parseFloat(res.Result.RadionuclideHalfLife) || null,
-          RadiopharmaceuticalStartTime: parseFloat(res.Result.RadiopharmaceuticalStartTime) || '',
-          AcquisitionTime: parseFloat(res.Result.AcquisitionTime) || '',
+          RadiopharmaceuticalStartTime: this.normalizeClinicalTime(res.Result.RadiopharmaceuticalStartTime),
+          AcquisitionTime: this.normalizeClinicalTime(res.Result.AcquisitionTime),
           TimeCheck: ''
         }
         this.computeTimeRelation()
@@ -1140,6 +1211,7 @@ export default {
       try {
         let valid = await this.$refs.patientForm.validate()
         if (!valid) return
+        this.normalizeTimeFields()
         this.formLoading = true
         let res = await editPatientInfo(this.formData)
         this.formLoading = false
diff --git a/src/views/trials/trials-panel/visit/crc-upload/components/uploadPetClinicalData.vue b/src/views/trials/trials-panel/visit/crc-upload/components/uploadPetClinicalData.vue
index ed6a8c8d..662cb2e7 100644
--- a/src/views/trials/trials-panel/visit/crc-upload/components/uploadPetClinicalData.vue
+++ b/src/views/trials/trials-panel/visit/crc-upload/components/uploadPetClinicalData.vue
@@ -277,23 +277,27 @@
             </el-form-item>
           </div>
           <div class="form-row">
-            <!-- 注射时间（s） Unix 秒 或 相对秒-->
+            <!-- 注射时间 HHMMSS-->
             <el-form-item class="form-item-half" :label="$t('trials:ptData:label:injectTime')" prop="RadiopharmaceuticalStartTime">
               <el-input
-                v-model.number="formData.RadiopharmaceuticalStartTime"
+                v-model.trim="formData.RadiopharmaceuticalStartTime"
                 :placeholder="$t('trials:injectTime:eg')"
                 style="width: 100%"
                 @input="computeTimeRelation"
+                @blur="handleTimeBlur('RadiopharmaceuticalStartTime')"
+                maxlength="6"
                 :disabled="!isPatientFormCanEdit"
               ></el-input>
             </el-form-item>
-            <!-- 成像时间（s） Unix 秒 或 相对秒-->
+            <!-- 成像时间 HHMMSS-->
             <el-form-item class="form-item-half" :label="$t('trials:ptData:label:acquisitionTime')" prop="AcquisitionTime">
               <el-input
-                v-model.number="formData.AcquisitionTime"
+                v-model.trim="formData.AcquisitionTime"
                 :placeholder="$t('trials:injectTime:eg')"
                 style="width: 100%"
                 @input="computeTimeRelation"
+                @blur="handleTimeBlur('AcquisitionTime')"
+                maxlength="6"
                 :disabled="!isPatientFormCanEdit"
               ></el-input>
             </el-form-item>
@@ -469,8 +473,8 @@ export default {
         PatientWeight: null,
         RadionuclideTotalDose: null,
         RadionuclideHalfLife: null,
-        RadiopharmaceuticalStartTime: null,
-        AcquisitionTime: null,
+        RadiopharmaceuticalStartTime: '',
+        AcquisitionTime: '',
         TimeCheck: '',
         Reason: ''
       },
@@ -492,11 +496,11 @@ export default {
         ],
         RadiopharmaceuticalStartTime: [
           { required: true, message: this.$t('common:ruleMessage:specify'), trigger: 'blur' },
-          { type: 'number', message: this.$t('trials:ptData:ruleMessage:number2'), trigger: 'blur' }//请输入数字
+          { validator: this.validateDicomTime, trigger: 'blur' }
         ],
         AcquisitionTime: [
           { required: true, message: this.$t('common:ruleMessage:specify'), trigger: 'blur' },
-          { type: 'number', message: this.$t('trials:ptData:ruleMessage:number2'), trigger: 'blur' },//请输入数字
+          { validator: this.validateDicomTime, trigger: 'blur' },
           // 自定义校验：确保成像时间不早于注射时间
           { validator: this.validateTime, trigger: 'blur' }
         ],
@@ -814,12 +818,68 @@ export default {
     // 时间一致性校验
     validateTime(rule, value, callback) {
       const { RadiopharmaceuticalStartTime } = this.formData
-      if (value && RadiopharmaceuticalStartTime !== null && value < RadiopharmaceuticalStartTime) {
+      const acquireSeconds = this.timeToSeconds(value)
+      const startSeconds = this.timeToSeconds(RadiopharmaceuticalStartTime)
+      if (acquireSeconds !== null && startSeconds !== null && acquireSeconds < startSeconds) {
         callback(new Error(this.$t('trials:ptData:ruleMessage:number3')))//成像时间不能早于注射时间
       } else {
         callback()
       }
     },
+    validateDicomTime(rule, value, callback) {
+      if (value === undefined || value === null || value === '') {
+        callback()
+        return
+      }
+      const raw = String(value).trim()
+      if (!/^\d{1,6}$/.test(raw)) {
+        callback(new Error(this.$t('trials:ptData:ruleMessage:number2')))
+        return
+      }
+      const normalized = this.normalizeClinicalTime(raw)
+      if (!this.isValidDicomTime(normalized)) {
+        callback(new Error(this.$t('trials:ptData:ruleMessage:number4')))//请输入有效时间（HHMMSS）
+        return
+      }
+      callback()
+    },
+    normalizeClinicalTime(value) {
+      if (value === undefined || value === null || value === '') return ''
+      const digits = String(value).trim().replace(/[^\d]/g, '')
+      if (!digits) return ''
+      return digits.slice(0, 6).padStart(6, '0')
+    },
+    isValidDicomTime(value) {
+      if (!/^\d{6}$/.test(String(value || ''))) return false
+      const normalized = String(value)
+      const hh = Number(normalized.slice(0, 2))
+      const mm = Number(normalized.slice(2, 4))
+      const ss = Number(normalized.slice(4, 6))
+      return hh >= 0 && hh <= 23 && mm >= 0 && mm <= 59 && ss >= 0 && ss <= 59
+    },
+    timeToSeconds(value) {
+      const normalized = this.normalizeClinicalTime(value)
+      if (!this.isValidDicomTime(normalized)) return null
+      const hh = Number(normalized.slice(0, 2))
+      const mm = Number(normalized.slice(2, 4))
+      const ss = Number(normalized.slice(4, 6))
+      return hh * 3600 + mm * 60 + ss
+    },
+    handleTimeBlur(field) {
+      const value = this.formData[field]
+      if (value === undefined || value === null || value === '') return
+      this.formData[field] = this.normalizeClinicalTime(value)
+      this.computeTimeRelation()
+    },
+    normalizeTimeFields() {
+      this.formData.RadiopharmaceuticalStartTime = this.normalizeClinicalTime(
+        this.formData.RadiopharmaceuticalStartTime
+      )
+      this.formData.AcquisitionTime = this.normalizeClinicalTime(
+        this.formData.AcquisitionTime
+      )
+      this.computeTimeRelation()
+    },
     computeTimeRelation() {
       const startTime = this.formData.RadiopharmaceuticalStartTime
       const acquireTime = this.formData.AcquisitionTime
@@ -829,7 +889,14 @@ export default {
         return
       }
 
-      if (startTime <= acquireTime) {
+      const startSeconds = this.timeToSeconds(startTime)
+      const acquireSeconds = this.timeToSeconds(acquireTime)
+      if (startSeconds === null || acquireSeconds === null) {
+        this.formData.TimeCheck = ''
+        return
+      }
+
+      if (startSeconds <= acquireSeconds) {
         this.formData.TimeCheck = this.$t('trials:ptData:timeCheck:val1') //注射时间 ≤ 成像时间
       } else {
         this.formData.TimeCheck = this.$t('trials:ptData:timeCheck:val2') //注射时间 > 成像时间
@@ -847,8 +914,8 @@ export default {
             PatientWeight: parseFloat(res.Result.PatientWeight) || null,
             RadionuclideTotalDose: parseFloat(res.Result.RadionuclideTotalDose) || null,
             RadionuclideHalfLife: parseFloat(res.Result.RadionuclideHalfLife) || null,
-            RadiopharmaceuticalStartTime: parseFloat(res.Result.RadiopharmaceuticalStartTime) || '',
-            AcquisitionTime: parseFloat(res.Result.AcquisitionTime) || '',
+            RadiopharmaceuticalStartTime: this.normalizeClinicalTime(res.Result.RadiopharmaceuticalStartTime),
+            AcquisitionTime: this.normalizeClinicalTime(res.Result.AcquisitionTime),
             TimeCheck: '',
             Reason: res.Result.Reason
           }
@@ -865,10 +932,12 @@ export default {
         let valid = await this.$refs.patientForm.validate()
         if (!valid) return
         if (this.isAudit) {
+          this.normalizeTimeFields()
           const { CorrectImageExaminationInformation } = const_.processSignature
           this.signCode = CorrectImageExaminationInformation
           this.signVisible = true
         } else {
+          this.normalizeTimeFields()
           this.formLoading = true
           let res = await editPatientInfo(this.formData)
           this.formLoading = false