diff --git a/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue b/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue
index 2dd19acb..634c0b10 100644
--- a/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue
+++ b/src/views/trials/trials-panel/reading/dicoms3D/components/Segmentations.vue
@@ -158,7 +158,8 @@
                             <i class="el-icon-warning-outline" style="color:red;margin-right: 5px;"
                                 :title="$t('trials:reading:Segmentations:tip:segmentationIsNotSave')"
                                 v-if="!curSegmentGroup.isSaved"></i>
-                            <el-button type="success" size="small" @click="saveSegmentGroup([curSegmentGroup])">
+                            <el-button type="success" size="small" :disabled="saveLoading"
+                                @click="saveSegmentGroup([curSegmentGroup])">
                                 {{ $t("trials:reading:Segmentations:button:save") }}
                             </el-button>
                         </div>
@@ -243,7 +244,7 @@
             </el-collapse-item>
         </el-collapse>
         <div class="saveBtnBox">
-            <el-button type="success" size="small" @click="saveSegmentGroup()">
+            <el-button type="success" size="small" :disabled="saveLoading" @click="saveSegmentGroup()">
                 {{ $t("trials:reading:Segmentations:button:saveAll") }}
             </el-button>
         </div>
@@ -367,7 +368,8 @@ export default {
             // isDel: false,
             digitPlaces: 2,
             isloaded: false,
-            popoverId: null
+            popoverId: null,
+            saveLoading: false
         }
     },
     mounted() {
@@ -1249,36 +1251,42 @@ export default {
             this.drawing = true
         },
         async calculateStatistics(indices, segmentationId, mode) {
-            if (!segmentation.state.getSegmentation(segmentationId)) return false
-            const stats = await segmentationUtils.getStatistics({
-                segmentationId,
-                segmentIndices: indices,
-                mode,
-            });
-            console.log(stats)
-            if (mode === 'individual') {
-                const segmentStats = stats;
+            try {
+                if (!segmentation.state.getSegmentation(segmentationId)) return false
+                this.saveLoading = true
+                const stats = await segmentationUtils.getStatistics({
+                    segmentationId,
+                    segmentIndices: indices,
+                    mode,
+                });
+                console.log(stats)
+                if (mode === 'individual') {
+                    const segmentStats = stats;
+
+                    for (const segmentIndex of indices) {
+                        if (segmentStats[segmentIndex]) {
+                            const segmentStat = segmentStats[segmentIndex];
+                            // console.log(segmentStat, 'segmentStat')
+                            segmentStat.count.label = 'Voxels';
+                            let segmentGroup = this.segmentList.find(item => item.segmentationId === segmentationId)
+                            if (segmentGroup) {
+                                let segment = segmentGroup.segments.find(item => item.segmentIndex === segmentIndex)
+                                segment.stats = segmentStat;
+                            }
 
-                for (const segmentIndex of indices) {
-                    if (segmentStats[segmentIndex]) {
-                        const segmentStat = segmentStats[segmentIndex];
-                        // console.log(segmentStat, 'segmentStat')
-                        segmentStat.count.label = 'Voxels';
-                        let segmentGroup = this.segmentList.find(item => item.segmentationId === segmentationId)
-                        if (segmentGroup) {
-                            let segment = segmentGroup.segments.find(item => item.segmentIndex === segmentIndex)
-                            segment.stats = segmentStat;
                         }
-
                     }
+                } else {
+                    const items = [`Statistics on ${indices.join(', ')}`];
+                    const namedStats = stats;
+                    namedStats.count.label = 'Voxels';
+
                 }
-            } else {
-                const items = [`Statistics on ${indices.join(', ')}`];
-                const namedStats = stats;
-                namedStats.count.label = 'Voxels';
-
+                this.saveLoading = false
+            } catch (err) {
+                console.log(err)
+                this.saveLoading = false
             }
-
         },
         createSegmentationRepresentation(segmentationId) {
             this.viewprotIds.forEach(id => {